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The map label for this gene is sohB [H]

Identifier: 62184771

GI number: 62184771

Start: 133198

End: 134205

Strand: Direct

Name: sohB [H]

Synonym: CAB126

Alternate gene names: 62184771

Gene position: 133198-134205 (Clockwise)

Preceding gene: 62184770

Following gene: 62184772

Centisome position: 11.64

GC content: 39.19

Gene sequence:

>1008_bases
GTGTTTATGAAAACGTTTTGGCATTTTATGTCTAAAGGCTTCCTATCAATTCTAGGTTTATCTCTGGGTGTAGTTCTTGC
TTTCTTTGTTACTGTGATGTTGGTTGTTTCTACCTCTGGAATGCACGACTCACAATTTGTGAATATGCCTGATGCTAAGG
GAGAAGTCAAAGATGTAGGCAAAGATGCTCCCATTATTGCTGTATTGGAAATGAAGGATGTGATTGCTTCTAGCAAACAC
ACCGCAAAAATCATTCAAGAGGCAATTACAACATTAGATTCCCCACCATACAAAGATAGAGTGAAGGGCATAATCATCGA
TATGGATTGCCCTGGAGGAGAGGTATTCGAAATTTCTCGAGTCTATTCAACAATTCAGTTTTGGAAACAGCGTACGCAAT
GTCCTGTTTACGTTTTTGTCAACGGTCTGTGTGCTTCCGGTGGGTATTATGTTGCTTGTGCTGCGGACAAAATTTATTCC
ACATCGTCTTCTTTAATAGGGTCTATAGGAGTGCTTTCAGGGCCATATTTTAATGTCAAAGAAGGCTTATCTCGTTATGG
TGTGCAAAGCGATTTGCTTATCGCAGGGAAAGATAAAGCCCCTATGAATCCTTATACAGAGTGGACAGCTAAAGATCGTG
AGATTCGTCAAGAAATTATAGATTATCTTTATGGTCAATTTGTCGATGTTGTGGTCACAAATCGCCCGCTATTAACTAAA
GATAAGCTTGTTAGCGTGTTAGGTGCCCGTCTATATTCACCTGAAAAGGCTTTAGAAGAAGGTTACATTGATGTAACGAA
CGTAACTAAACAACAAGTCTTACAAGATTTAGTCGCCGATTGCAAAATTGAAAATAACTACCGTGTGATTGGTTTAGGCA
GTGATGGCTGGTTGAAAAGAGTTATGTCATCAATAACGAACAGCCCTGTAATCACAGGAAAGATTCAACATGAGTTGCTC
CCAAGCTTAGATAATTCCATAAGTACATTTTACTACTTAGATTCGTGA

Upstream 100 bases:

>100_bases
TAAAGGGCGTTTACGCCCTTTTTATTCATATTCTTTTTGATCTTTAAGCTTTCCCTCACATACCTTATTATATTTGTTCT
ATAAATTTTTGACGTTACGG

Downstream 100 bases:

>100_bases
TTCTGATTCATAGGGCGGAGAGAATTAGTGAGAAAGGTCTTTATTTTAGATGCTTCAGGATTTGTTTTTAGAGCATATTT
TGCTCTCCCTGATATGAAAA

Product: putative exported protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MFMKTFWHFMSKGFLSILGLSLGVVLAFFVTVMLVVSTSGMHDSQFVNMPDAKGEVKDVGKDAPIIAVLEMKDVIASSKH
TAKIIQEAITTLDSPPYKDRVKGIIIDMDCPGGEVFEISRVYSTIQFWKQRTQCPVYVFVNGLCASGGYYVACAADKIYS
TSSSLIGSIGVLSGPYFNVKEGLSRYGVQSDLLIAGKDKAPMNPYTEWTAKDREIRQEIIDYLYGQFVDVVVTNRPLLTK
DKLVSVLGARLYSPEKALEEGYIDVTNVTKQQVLQDLVADCKIENNYRVIGLGSDGWLKRVMSSITNSPVITGKIQHELL
PSLDNSISTFYYLDS

Sequences:

>Translated_335_residues
MFMKTFWHFMSKGFLSILGLSLGVVLAFFVTVMLVVSTSGMHDSQFVNMPDAKGEVKDVGKDAPIIAVLEMKDVIASSKH
TAKIIQEAITTLDSPPYKDRVKGIIIDMDCPGGEVFEISRVYSTIQFWKQRTQCPVYVFVNGLCASGGYYVACAADKIYS
TSSSLIGSIGVLSGPYFNVKEGLSRYGVQSDLLIAGKDKAPMNPYTEWTAKDREIRQEIIDYLYGQFVDVVVTNRPLLTK
DKLVSVLGARLYSPEKALEEGYIDVTNVTKQQVLQDLVADCKIENNYRVIGLGSDGWLKRVMSSITNSPVITGKIQHELL
PSLDNSISTFYYLDS
>Mature_335_residues
MFMKTFWHFMSKGFLSILGLSLGVVLAFFVTVMLVVSTSGMHDSQFVNMPDAKGEVKDVGKDAPIIAVLEMKDVIASSKH
TAKIIQEAITTLDSPPYKDRVKGIIIDMDCPGGEVFEISRVYSTIQFWKQRTQCPVYVFVNGLCASGGYYVACAADKIYS
TSSSLIGSIGVLSGPYFNVKEGLSRYGVQSDLLIAGKDKAPMNPYTEWTAKDREIRQEIIDYLYGQFVDVVVTNRPLLTK
DKLVSVLGARLYSPEKALEEGYIDVTNVTKQQVLQDLVADCKIENNYRVIGLGSDGWLKRVMSSITNSPVITGKIQHELL
PSLDNSISTFYYLDS

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=223, Percent_Identity=30.4932735426009, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 37115; Mature: 37115

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMKTFWHFMSKGFLSILGLSLGVVLAFFVTVMLVVSTSGMHDSQFVNMPDAKGEVKDVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHCC
KDAPIIAVLEMKDVIASSKHTAKIIQEAITTLDSPPYKDRVKGIIIDMDCPGGEVFEISR
CCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCCCCHHHHHH
VYSTIQFWKQRTQCPVYVFVNGLCASGGYYVACAADKIYSTSSSLIGSIGVLSGPYFNVK
HHHHHHHHHHHCCCEEEEEEECEECCCCEEEEEECCHHHCCHHHHHHHHHHCCCCCCCHH
EGLSRYGVQSDLLIAGKDKAPMNPYTEWTAKDREIRQEIIDYLYGQFVDVVVTNRPLLTK
HHHHHHCCCCCEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DKLVSVLGARLYSPEKALEEGYIDVTNVTKQQVLQDLVADCKIENNYRVIGLGSDGWLKR
HHHHHHHHHHHCCHHHHHHCCCEEHHHHHHHHHHHHHHHHCEECCCEEEEEECCCHHHHH
VMSSITNSPVITGKIQHELLPSLDNSISTFYYLDS
HHHHHCCCCEEEEHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MFMKTFWHFMSKGFLSILGLSLGVVLAFFVTVMLVVSTSGMHDSQFVNMPDAKGEVKDVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHCC
KDAPIIAVLEMKDVIASSKHTAKIIQEAITTLDSPPYKDRVKGIIIDMDCPGGEVFEISR
CCCCEEEEEEHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCCCCHHHHHH
VYSTIQFWKQRTQCPVYVFVNGLCASGGYYVACAADKIYSTSSSLIGSIGVLSGPYFNVK
HHHHHHHHHHHCCCEEEEEEECEECCCCEEEEEECCHHHCCHHHHHHHHHHCCCCCCCHH
EGLSRYGVQSDLLIAGKDKAPMNPYTEWTAKDREIRQEIIDYLYGQFVDVVVTNRPLLTK
HHHHHHCCCCCEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DKLVSVLGARLYSPEKALEEGYIDVTNVTKQQVLQDLVADCKIENNYRVIGLGSDGWLKR
HHHHHHHHHHHCCHHHHHHCCCEEHHHHHHHHHHHHHHHHCEECCCEEEEEECCCHHHHH
VMSSITNSPVITGKIQHELLPSLDNSISTFYYLDS
HHHHHCCCCEEEEHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]