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The map label for this gene is gapA [H]

Identifier: 62184760

GI number: 62184760

Start: 120638

End: 121645

Strand: Direct

Name: gapA [H]

Synonym: CAB115

Alternate gene names: 62184760

Gene position: 120638-121645 (Clockwise)

Preceding gene: 62184759

Following gene: 62184761

Centisome position: 10.54

GC content: 38.49

Gene sequence:

>1008_bases
ATGAAAGTTGTAATTAACGGTTTTGGTCGGATAGGAAGATTAGTTTTAAGACAATTTCTGAAAAGAAATTCTTCTATCGA
AGTTGTGGCTGTTAATGATCTTGTCCCAGGAGAAGCGTTAACATACCTGTTTAAATATGATTCTACTCACGGCCGCTTCC
CAGCAGAAGTATCTCATGAAAATGGCTGTCTCGTTGTTGATGGTCGTAGAATTCAATTGTTAGCTCAATCTGACGTTCAA
AAGCTTCCCTGGAAGGATCTAGGTGTAGATATTGTCATCGAAAGTACAGGTTTGTTCACTAAAAAAGAAGATGCAGAAAA
ACATCTCGCTTCTGGTGCTAAACGTGTTTTGATTACAGCTCCTGCAAAAGGTGATGTCCCCACATTTGTCATGGGAGTAA
ATGAACATAAGTTTGATCCTGAAAAAGATCTAATTATTTCTAATGCTTCCTGTACTACAAATTGTCTCGCTCCCTTAGCT
AAGGTTTTATTGGATAGTTTTGGTATAGAAGAAGGTTTAATGACCACCGTGCATGCCGCTACAGCCACACAAAGCGTTGT
AGACGGTCCTTCAAAAAAAGATTGGAGAGGTGGTAGAGGCGCTTTTCAAAATATCATTCCTGCTTCTACTGGAGCTGCGA
AAGCTGTTGCTCTATGTTTGCCTGAACTCAAGAATAAATTAACTGGGATGGCGTTTAGAGTTCCTGTGGCTGATGTTTCT
GTAGTTGACCTTACTGTAAGATTGCAGAAGTCAACCTCATATGAAGAAATATGTAAGGTTGTTAAAGAAGCTTCAGAAGC
TCATTTAAGTGGGATTTTAGGTTATACAGATCAAGAAGTCGTTTCTTCTGATTTTATAGGATGTGAATATTCTTCTATAT
TTGATGCCGGCGCAGGGATAGCCTTAACTGATCGCTTTTTCAAACTAGTTGCTTGGTATGATAATGAGATAGGATATGCA
ACCCGCATAGTTGATTTATTAGAGTATGTAGCAAAGAACTCTAAATAA

Upstream 100 bases:

>100_bases
AAATGCAAAATAGAGTTGGTGATAATGCACGAAAGTGTATTATAGAATTTTTAGCTAATTAGACTGTTTTTTTTGTAACA
CTGACTACTAGGGAATAGCG

Downstream 100 bases:

>100_bases
AAGGTTAAATTCGTGTATTTTACAAGAGATCCAGTTATTGAAACTGTTATTACTTCGAGGGAAGGGTACAAACTGTCAAT
TCGTAACACTAAGCAGCTTT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKVVINGFGRIGRLVLRQFLKRNSSIEVVAVNDLVPGEALTYLFKYDSTHGRFPAEVSHENGCLVVDGRRIQLLAQSDVQ
KLPWKDLGVDIVIESTGLFTKKEDAEKHLASGAKRVLITAPAKGDVPTFVMGVNEHKFDPEKDLIISNASCTTNCLAPLA
KVLLDSFGIEEGLMTTVHAATATQSVVDGPSKKDWRGGRGAFQNIIPASTGAAKAVALCLPELKNKLTGMAFRVPVADVS
VVDLTVRLQKSTSYEEICKVVKEASEAHLSGILGYTDQEVVSSDFIGCEYSSIFDAGAGIALTDRFFKLVAWYDNEIGYA
TRIVDLLEYVAKNSK

Sequences:

>Translated_335_residues
MKVVINGFGRIGRLVLRQFLKRNSSIEVVAVNDLVPGEALTYLFKYDSTHGRFPAEVSHENGCLVVDGRRIQLLAQSDVQ
KLPWKDLGVDIVIESTGLFTKKEDAEKHLASGAKRVLITAPAKGDVPTFVMGVNEHKFDPEKDLIISNASCTTNCLAPLA
KVLLDSFGIEEGLMTTVHAATATQSVVDGPSKKDWRGGRGAFQNIIPASTGAAKAVALCLPELKNKLTGMAFRVPVADVS
VVDLTVRLQKSTSYEEICKVVKEASEAHLSGILGYTDQEVVSSDFIGCEYSSIFDAGAGIALTDRFFKLVAWYDNEIGYA
TRIVDLLEYVAKNSK
>Mature_335_residues
MKVVINGFGRIGRLVLRQFLKRNSSIEVVAVNDLVPGEALTYLFKYDSTHGRFPAEVSHENGCLVVDGRRIQLLAQSDVQ
KLPWKDLGVDIVIESTGLFTKKEDAEKHLASGAKRVLITAPAKGDVPTFVMGVNEHKFDPEKDLIISNASCTTNCLAPLA
KVLLDSFGIEEGLMTTVHAATATQSVVDGPSKKDWRGGRGAFQNIIPASTGAAKAVALCLPELKNKLTGMAFRVPVADVS
VVDLTVRLQKSTSYEEICKVVKEASEAHLSGILGYTDQEVVSSDFIGCEYSSIFDAGAGIALTDRFFKLVAWYDNEIGYA
TRIVDLLEYVAKNSK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=60.8433734939759, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI7657116, Length=336, Percent_Identity=57.7380952380952, Blast_Score=393, Evalue=1e-109,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=59.3373493975904, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1789295, Length=328, Percent_Identity=39.3292682926829, Blast_Score=250, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=59.4029850746269, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=58.5074626865672, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17568413, Length=335, Percent_Identity=59.4029850746269, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=58.5074626865672, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=62.874251497006, Blast_Score=423, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=62.874251497006, Blast_Score=421, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=59.7597597597598, Blast_Score=412, Evalue=1e-116,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=58.1818181818182, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=58.1818181818182, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=58.4848484848485, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=58.4848484848485, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=57.7981651376147, Blast_Score=373, Evalue=1e-103,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36371; Mature: 36371

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVINGFGRIGRLVLRQFLKRNSSIEVVAVNDLVPGEALTYLFKYDSTHGRFPAEVSHE
CEEEEECHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHEEEEEECCCCCCCCCCCCCC
NGCLVVDGRRIQLLAQSDVQKLPWKDLGVDIVIESTGLFTKKEDAEKHLASGAKRVLITA
CCEEEECCCEEEEEECCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEC
PAKGDVPTFVMGVNEHKFDPEKDLIISNASCTTNCLAPLAKVLLDSFGIEEGLMTTVHAA
CCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TATQSVVDGPSKKDWRGGRGAFQNIIPASTGAAKAVALCLPELKNKLTGMAFRVPVADVS
HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCEE
VVDLTVRLQKSTSYEEICKVVKEASEAHLSGILGYTDQEVVSSDFIGCEYSSIFDAGAGI
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHCCCCCE
ALTDRFFKLVAWYDNEIGYATRIVDLLEYVAKNSK
EHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVVINGFGRIGRLVLRQFLKRNSSIEVVAVNDLVPGEALTYLFKYDSTHGRFPAEVSHE
CEEEEECHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHEEEEEECCCCCCCCCCCCCC
NGCLVVDGRRIQLLAQSDVQKLPWKDLGVDIVIESTGLFTKKEDAEKHLASGAKRVLITA
CCEEEECCCEEEEEECCCHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEC
PAKGDVPTFVMGVNEHKFDPEKDLIISNASCTTNCLAPLAKVLLDSFGIEEGLMTTVHAA
CCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TATQSVVDGPSKKDWRGGRGAFQNIIPASTGAAKAVALCLPELKNKLTGMAFRVPVADVS
HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCEE
VVDLTVRLQKSTSYEEICKVVKEASEAHLSGILGYTDQEVVSSDFIGCEYSSIFDAGAGI
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHCCCCCE
ALTDRFFKLVAWYDNEIGYATRIVDLLEYVAKNSK
EHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]