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The map label for this gene is hemA

Identifier: 62184675

GI number: 62184675

Start: 38121

End: 39137

Strand: Direct

Name: hemA

Synonym: CAB028

Alternate gene names: 62184675

Gene position: 38121-39137 (Clockwise)

Preceding gene: 62184665

Following gene: 62184676

Centisome position: 3.33

GC content: 37.46

Gene sequence:

>1017_bases
ATGGTTCTAGGAGTTGTTGGAATTAGCTATCGAGAGGCTGCTTTAAAAGAAAGGGAAGCAGTAATTAATATCTTGAAGGA
TTTTGAAGCTAATTCTTTTTTTTCTCAGCATTTTTTCGGTGATGACGGATCTTTCGTTTTATTGCTAACATGTCATAGAG
CGGAAATTTACTATTTTTCTAAAAGTAATCGTCATATTCAATCAAAGTTACTGTCGCGGATTTCTTCGTTAGGAGCACGT
CCTTATTGTTATCAAGGACTCGCGTGCTTTACGCATTTATTTACCGTAACTAGTGGTATGGATAGCTTAATTTCTGGAGA
GACCGAAATACAAGGCCAAGTAAAACGCGCGTATATAAAAGCAAAAACAGATCGAGACTTACCCTTCGCTCTACATTTTT
TATTTCAGAAGGCTTTAAAAGAAGGAAAGGATTTTCGTTCTCAAGTCTCTTTGTCTCATCCTGTTGTAACGATTGAGTCT
GTCGTTGAAGAAACTCTAGACTTGCATGGTAAATCAACAAAAGACAAACTTTTATTTATCGGTTACTCCGAGATTAATCG
GAAGATCGCAAAGGGGTTGAGTGCGAAAGGTTACCGAAATCTAATTTTTTGCTCTCGAAAAAATATTTCCATACCATACG
ATACAGTGGCTCGTAGTCAACTTTCTTTTAGGGAACCCTATGATGTCATTTTCTTCGGATCATCGGAATCAGCTAAAGAT
TTTTCCGGGTTATCTTTAGAAAGTTTGGCCAGCATCCCCAGCCGTGTGATTTTTGATTTTAATGTTCCGCGTACCTTTAC
TTTGGCGGAAAGTCCGAAAGATATCATATGTTTGGATATGGATTTTATTAGCGAGCGTGTGCAGAAAAAACTCCAAATTA
GTAAGCAATGTACAAATAAAGAAAAACCATTTTTAGCTCTAGCAGCAAGAAAACAATGGGAAGTTTATGAAAAAAAGAGC
TCACATATACCTTCGAGCCAGGTTCGAGCTTCTCGTCCTAAGCTGTTGATTCTTTAG

Upstream 100 bases:

>100_bases
ATTTTGTCTTGGGCTATACACCTAGATTACTTTCGCTCTCCATTCTCTATTATTTTTCTCATGTTTAGAGGATAAGCGGA
AAACTTATTGCAACGTGCTT

Downstream 100 bases:

>100_bases
CGTCTAATTCATCTCTTGACATATACAGCTATCGAAAATACTCTAGGCTTTCATCGTTAACTCCGATGAATTTGTATGCA
AGTGTGGTCTAGTACTGGCA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVLGVVGISYREAALKEREAVINILKDFEANSFFSQHFFGDDGSFVLLLTCHRAEIYYFSKSNRHIQSKLLSRISSLGAR
PYCYQGLACFTHLFTVTSGMDSLISGETEIQGQVKRAYIKAKTDRDLPFALHFLFQKALKEGKDFRSQVSLSHPVVTIES
VVEETLDLHGKSTKDKLLFIGYSEINRKIAKGLSAKGYRNLIFCSRKNISIPYDTVARSQLSFREPYDVIFFGSSESAKD
FSGLSLESLASIPSRVIFDFNVPRTFTLAESPKDIICLDMDFISERVQKKLQISKQCTNKEKPFLALAARKQWEVYEKKS
SHIPSSQVRASRPKLLIL

Sequences:

>Translated_338_residues
MVLGVVGISYREAALKEREAVINILKDFEANSFFSQHFFGDDGSFVLLLTCHRAEIYYFSKSNRHIQSKLLSRISSLGAR
PYCYQGLACFTHLFTVTSGMDSLISGETEIQGQVKRAYIKAKTDRDLPFALHFLFQKALKEGKDFRSQVSLSHPVVTIES
VVEETLDLHGKSTKDKLLFIGYSEINRKIAKGLSAKGYRNLIFCSRKNISIPYDTVARSQLSFREPYDVIFFGSSESAKD
FSGLSLESLASIPSRVIFDFNVPRTFTLAESPKDIICLDMDFISERVQKKLQISKQCTNKEKPFLALAARKQWEVYEKKS
SHIPSSQVRASRPKLLIL
>Mature_338_residues
MVLGVVGISYREAALKEREAVINILKDFEANSFFSQHFFGDDGSFVLLLTCHRAEIYYFSKSNRHIQSKLLSRISSLGAR
PYCYQGLACFTHLFTVTSGMDSLISGETEIQGQVKRAYIKAKTDRDLPFALHFLFQKALKEGKDFRSQVSLSHPVVTIES
VVEETLDLHGKSTKDKLLFIGYSEINRKIAKGLSAKGYRNLIFCSRKNISIPYDTVARSQLSFREPYDVIFFGSSESAKD
FSGLSLESLASIPSRVIFDFNVPRTFTLAESPKDIICLDMDFISERVQKKLQISKQCTNKEKPFLALAARKQWEVYEKKS
SHIPSSQVRASRPKLLIL

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HEM1_CHLAB (Q5L782)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_219460.1
- ProteinModelPortal:   Q5L782
- SMR:   Q5L782
- GeneID:   3337916
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB028
- HOGENOM:   HBG413932
- OMA:   IFFGSSE
- ProtClustDB:   PRK00676
- BioCyc:   CABO218497:CAB028-MONOMER
- HAMAP:   MF_00087
- InterPro:   IPR000343
- InterPro:   IPR015895
- InterPro:   IPR018214

Pfam domain/function: PF05201 GlutR_N; SSF69742 GlutR

EC number: =1.2.1.70

Molecular weight: Translated: 38301; Mature: 38301

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00747 GLUTR

Important sites: ACT_SITE 51-51 BINDING 102-102 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLGVVGISYREAALKEREAVINILKDFEANSFFSQHFFGDDGSFVLLLTCHRAEIYYFS
CEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCEEEEEEEECEEEEEEE
KSNRHIQSKLLSRISSLGARPYCYQGLACFTHLFTVTSGMDSLISGETEIQGQVKRAYIK
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHEE
AKTDRDLPFALHFLFQKALKEGKDFRSQVSLSHPVVTIESVVEETLDLHGKSTKDKLLFI
ECCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCEEEE
GYSEINRKIAKGLSAKGYRNLIFCSRKNISIPYDTVARSQLSFREPYDVIFFGSSESAKD
EHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCC
FSGLSLESLASIPSRVIFDFNVPRTFTLAESPKDIICLDMDFISERVQKKLQISKQCTNK
CCCCCHHHHHCCCCCEEEECCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC
EKPFLALAARKQWEVYEKKSSHIPSSQVRASRPKLLIL
CCCEEEEHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEC
>Mature Secondary Structure
MVLGVVGISYREAALKEREAVINILKDFEANSFFSQHFFGDDGSFVLLLTCHRAEIYYFS
CEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCEEEEEEEECEEEEEEE
KSNRHIQSKLLSRISSLGARPYCYQGLACFTHLFTVTSGMDSLISGETEIQGQVKRAYIK
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHEE
AKTDRDLPFALHFLFQKALKEGKDFRSQVSLSHPVVTIESVVEETLDLHGKSTKDKLLFI
ECCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCEEEE
GYSEINRKIAKGLSAKGYRNLIFCSRKNISIPYDTVARSQLSFREPYDVIFFGSSESAKD
EHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCC
FSGLSLESLASIPSRVIFDFNVPRTFTLAESPKDIICLDMDFISERVQKKLQISKQCTNK
CCCCCHHHHHCCCCCEEEECCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC
EKPFLALAARKQWEVYEKKSSHIPSSQVRASRPKLLIL
CCCEEEEHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA