Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 161501897

GI number: 161501897

Start: 124503

End: 125126

Strand: Direct

Name: ruvA

Synonym: CAB119

Alternate gene names: 161501897

Gene position: 124503-125126 (Clockwise)

Preceding gene: 161501898

Following gene: 62184765

Centisome position: 10.88

GC content: 40.87

Gene sequence:

>624_bases
ATGTACGACTATATTCGTGGTGTGCTTACTTATATCAGTTCAAGCACTATGGTGATTGAAAGTCAGGGATTGGGATTTAG
TATTTTTGCTCCTGAGAGATGGCTGATCGAACTGTCAAGTCAACTACACCGAGAGCTTATAGTGTATACGTATACTGTTG
TTCGTGAAACTGAGCATGTTCTCTATGGATTTCATACTCGTGGAGAACGCGAGTGTTTCCGTATGTTAATCTCCTTTTCA
GGAGTGGGACCTAAGACAGGTTTAGCGATTTTAAATACATTTTCTCTTAGCCAATTGTGTTCTATAGCTCGTGCTGAAGA
TATAAAAGCTATAGCTTCTGTTCCGGGCATAGGTAAGAAAACTGCTGAGAAGCTTATGGTCGATTTAAAGCAAAAGCTTG
CAGACTTACTCCCTTTAGATGCACAAATACTCGCTTCTTGGGAACCAGCAAAACCTTCTTGTATGGAAGAAGGAATACAA
GCTTTAGCAGCATTAGGCTATCCAAAATCCTCGGCAGAGAGAATGATCGCCGAAGCTATGAGCGAGCTTCCAGATCATGC
GTCAGTAGCAGAAATTCTTCCTATTGCTTTAAAAAAGAATTTACAGGGGTTGAACAAGATCTAG

Upstream 100 bases:

>100_bases
CTGATGTTTTAAATTCGGATTGTGAGGATATTGCAGATGCATTTGCATTAGCGATATGCCACGCGCATACTTCTGCATAT
ACTTGTTTGGGAGTTCGATA

Downstream 100 bases:

>100_bases
ACTTTCCTGAAGATCGTGGTATAATTTCCTCCACCATTTACTACATGTTGTTTAAGGAGATTATATATACATGGAACAAA
CGCTATCAATTATCAAACCT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MYDYIRGVLTYISSSTMVIESQGLGFSIFAPERWLIELSSQLHRELIVYTYTVVRETEHVLYGFHTRGERECFRMLISFS
GVGPKTGLAILNTFSLSQLCSIARAEDIKAIASVPGIGKKTAEKLMVDLKQKLADLLPLDAQILASWEPAKPSCMEEGIQ
ALAALGYPKSSAERMIAEAMSELPDHASVAEILPIALKKNLQGLNKI

Sequences:

>Translated_207_residues
MYDYIRGVLTYISSSTMVIESQGLGFSIFAPERWLIELSSQLHRELIVYTYTVVRETEHVLYGFHTRGERECFRMLISFS
GVGPKTGLAILNTFSLSQLCSIARAEDIKAIASVPGIGKKTAEKLMVDLKQKLADLLPLDAQILASWEPAKPSCMEEGIQ
ALAALGYPKSSAERMIAEAMSELPDHASVAEILPIALKKNLQGLNKI
>Mature_207_residues
MYDYIRGVLTYISSSTMVIESQGLGFSIFAPERWLIELSSQLHRELIVYTYTVVRETEHVLYGFHTRGERECFRMLISFS
GVGPKTGLAILNTFSLSQLCSIARAEDIKAIASVPGIGKKTAEKLMVDLKQKLADLLPLDAQILASWEPAKPSCMEEGIQ
ALAALGYPKSSAERMIAEAMSELPDHASVAEILPIALKKNLQGLNKI

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=194, Percent_Identity=36.0824742268041, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_CHLAB (Q5L6Z3)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_219549.2
- ProteinModelPortal:   Q5L6Z3
- SMR:   Q5L6Z3
- GeneID:   3338123
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB119
- HOGENOM:   HBG635309
- PhylomeDB:   Q5L6Z3
- ProtClustDB:   PRK00116
- BioCyc:   CABO218497:CAB119-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 22833; Mature: 22833

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDYIRGVLTYISSSTMVIESQGLGFSIFAPERWLIELSSQLHRELIVYTYTVVRETEHV
CHHHHHHHHHHHCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGFHTRGERECFRMLISFSGVGPKTGLAILNTFSLSQLCSIARAEDIKAIASVPGIGKK
HEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TAEKLMVDLKQKLADLLPLDAQILASWEPAKPSCMEEGIQALAALGYPKSSAERMIAEAM
HHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SELPDHASVAEILPIALKKNLQGLNKI
HHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYDYIRGVLTYISSSTMVIESQGLGFSIFAPERWLIELSSQLHRELIVYTYTVVRETEHV
CHHHHHHHHHHHCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGFHTRGERECFRMLISFSGVGPKTGLAILNTFSLSQLCSIARAEDIKAIASVPGIGKK
HEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TAEKLMVDLKQKLADLLPLDAQILASWEPAKPSCMEEGIQALAALGYPKSSAERMIAEAM
HHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SELPDHASVAEILPIALKKNLQGLNKI
HHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA