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The map label for this gene is menC [H]

Identifier: 28572892

GI number: 28572892

Start: 847917

End: 849119

Strand: Direct

Name: menC [H]

Synonym: TW751

Alternate gene names: 28572892

Gene position: 847917-849119 (Clockwise)

Preceding gene: 28572891

Following gene: 28572893

Centisome position: 91.57

GC content: 44.47

Gene sequence:

>1203_bases
TTGATGGATTATCCGTCAATCGACACCCTCTTAGAATCTGCCCATATTGTTACTCTGCCCATGAAGTACCCTTTCATGGG
GCTTAGCGAACGTCAAGCTGTTCTGTTTGAAGGACCCAATTCTTGGGCCGAGTACTCCCCGTTCATGGGGTGCAATGATA
CAAGGATGTGGCTTGCGTCTGCAATTGAATATGGCTGGGGTAACACCAATGTGCTTTCTGTGCCAAATCTAGATTTGGAC
AACACTAATTTTGCGAGTAGATCAAAATACGGGTACATAGCAAATCCTCAAACGAGTAATAAGGACCATTCTGACAACAA
ACGGTTTTACACACAGACCAAAAACCACCGAGAGATCCCCGTTAACGCAATCCTTCCAGATATTCCTGCGAGTAAGATGT
CAGAGATTCTCGGCAAAGATCTGCAGGGGTGCAAATGCGTAAAAATAAAGGTCGGAAAGCATTTTCAAGATCGAGATATT
CACAGAATACGTGCGGTCCTAGATTTTATGGGAGCGGATACAATGCTCAGGCTGGACGCAAATTGCAAATGGAATGTTTC
AGAAACGCTCAACAATCTGGATGTACTAGAAGATAATGACCTTCTTGAAAATGTGTCCTACATCGAACAACCGTGCAGAA
CTACACGGGAGCTTATTACACTTAAGCAGAAGATGGATACCCGTGGATATGTAACTAAAATTGCGATCGATGAAAGCCTT
AGAGATCTGCTATTGCATTGGCAGAAAAATCGTAAATGGAGCAACAACTCGGGTATAACATACACAACAGAGCTTCGCGA
AACCCTATCAGCGTGTGACATGCTGGTTTTGAAGTTACAACCCATGGGTGGAATGCGCGCGGTGGCGGATTTACTCGAGA
GTATAAAAAACAATATCAAGGTGAATGTTGGATATACCGTATCATCATCCTTGGAAACTTCGCTCGGTATAGAAATGGGC
CTAGCTCTTGCTCTCAATTTGCCAAATATTACCCTGCCAGTAGGACTTGCAACCGCAGGTCTGTTGGATGCTGACATAAC
AGATGACCCACTTTTGCCAAACAAAGGGTACATAACCCCAAGAAAGATTGAGGTAAACAAAAAACTCCTTAACAGGTACG
CGGCCGATAAAAGGCACGTGGTATGGTGGCATCGACGAATTAGGGCAGCCCATAGAGCCCTTTTTCAGGATCTTTCCGAC
TGA

Upstream 100 bases:

>100_bases
AGTCACACAAATTTGCCGAGTCTATGGAAATACTGTTTGATGTAAAGACAGATTGTACGGAAGGCACACAATATCAATCA
TCCTGCGGGAAATCTTTCGA

Downstream 100 bases:

>100_bases
GAGAAGCTTTGTATGTCTGATACAAAACAACCACCATGTGACATAAATGCCGAGCGGGCACTGCTTGGCAGTGTCTTACT
CAGTAAAGACGCAGCGGCAG

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMDYPSIDTLLESAHIVTLPMKYPFMGLSERQAVLFEGPNSWAEYSPFMGCNDTRMWLASAIEYGWGNTNVLSVPNLDLD
NTNFASRSKYGYIANPQTSNKDHSDNKRFYTQTKNHREIPVNAILPDIPASKMSEILGKDLQGCKCVKIKVGKHFQDRDI
HRIRAVLDFMGADTMLRLDANCKWNVSETLNNLDVLEDNDLLENVSYIEQPCRTTRELITLKQKMDTRGYVTKIAIDESL
RDLLLHWQKNRKWSNNSGITYTTELRETLSACDMLVLKLQPMGGMRAVADLLESIKNNIKVNVGYTVSSSLETSLGIEMG
LALALNLPNITLPVGLATAGLLDADITDDPLLPNKGYITPRKIEVNKKLLNRYAADKRHVVWWHRRIRAAHRALFQDLSD

Sequences:

>Translated_400_residues
MMDYPSIDTLLESAHIVTLPMKYPFMGLSERQAVLFEGPNSWAEYSPFMGCNDTRMWLASAIEYGWGNTNVLSVPNLDLD
NTNFASRSKYGYIANPQTSNKDHSDNKRFYTQTKNHREIPVNAILPDIPASKMSEILGKDLQGCKCVKIKVGKHFQDRDI
HRIRAVLDFMGADTMLRLDANCKWNVSETLNNLDVLEDNDLLENVSYIEQPCRTTRELITLKQKMDTRGYVTKIAIDESL
RDLLLHWQKNRKWSNNSGITYTTELRETLSACDMLVLKLQPMGGMRAVADLLESIKNNIKVNVGYTVSSSLETSLGIEMG
LALALNLPNITLPVGLATAGLLDADITDDPLLPNKGYITPRKIEVNKKLLNRYAADKRHVVWWHRRIRAAHRALFQDLSD
>Mature_400_residues
MMDYPSIDTLLESAHIVTLPMKYPFMGLSERQAVLFEGPNSWAEYSPFMGCNDTRMWLASAIEYGWGNTNVLSVPNLDLD
NTNFASRSKYGYIANPQTSNKDHSDNKRFYTQTKNHREIPVNAILPDIPASKMSEILGKDLQGCKCVKIKVGKHFQDRDI
HRIRAVLDFMGADTMLRLDANCKWNVSETLNNLDVLEDNDLLENVSYIEQPCRTTRELITLKQKMDTRGYVTKIAIDESL
RDLLLHWQKNRKWSNNSGITYTTELRETLSACDMLVLKLQPMGGMRAVADLLESIKNNIKVNVGYTVSSSLETSLGIEMG
LALALNLPNITLPVGLATAGLLDADITDDPLLPNKGYITPRKIEVNKKLLNRYAADKRHVVWWHRRIRAAHRALFQDLSD

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 45362; Mature: 45362

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDYPSIDTLLESAHIVTLPMKYPFMGLSERQAVLFEGPNSWAEYSPFMGCNDTRMWLAS
CCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCHHCCCCCCCCHHHHHHHH
AIEYGWGNTNVLSVPNLDLDNTNFASRSKYGYIANPQTSNKDHSDNKRFYTQTKNHREIP
HHHCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCC
VNAILPDIPASKMSEILGKDLQGCKCVKIKVGKHFQDRDIHRIRAVLDFMGADTMLRLDA
HHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECC
NCKWNVSETLNNLDVLEDNDLLENVSYIEQPCRTTRELITLKQKMDTRGYVTKIAIDESL
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHH
RDLLLHWQKNRKWSNNSGITYTTELRETLSACDMLVLKLQPMGGMRAVADLLESIKNNIK
HHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCEE
VNVGYTVSSSLETSLGIEMGLALALNLPNITLPVGLATAGLLDADITDDPLLPNKGYITP
EEEEEEECCCCHHHHCHHCCEEEEEECCCEEEEHHHHHHCCEECCCCCCCCCCCCCCCCC
RKIEVNKKLLNRYAADKRHVVWWHRRIRAAHRALFQDLSD
CEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMDYPSIDTLLESAHIVTLPMKYPFMGLSERQAVLFEGPNSWAEYSPFMGCNDTRMWLAS
CCCCCCHHHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCHHCCCCCCCCHHHHHHHH
AIEYGWGNTNVLSVPNLDLDNTNFASRSKYGYIANPQTSNKDHSDNKRFYTQTKNHREIP
HHHCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCC
VNAILPDIPASKMSEILGKDLQGCKCVKIKVGKHFQDRDIHRIRAVLDFMGADTMLRLDA
HHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECC
NCKWNVSETLNNLDVLEDNDLLENVSYIEQPCRTTRELITLKQKMDTRGYVTKIAIDESL
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHH
RDLLLHWQKNRKWSNNSGITYTTELRETLSACDMLVLKLQPMGGMRAVADLLESIKNNIK
HHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCEE
VNVGYTVSSSLETSLGIEMGLALALNLPNITLPVGLATAGLLDADITDDPLLPNKGYITP
EEEEEEECCCCHHHHCHHCCEEEEEECCCEEEEHHHHHHCCEECCCCCCCCCCCCCCCCC
RKIEVNKKLLNRYAADKRHVVWWHRRIRAAHRALFQDLSD
CEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]