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The map label for this gene is engD [H]

Identifier: 28572802

GI number: 28572802

Start: 752772

End: 753806

Strand: Reverse

Name: engD [H]

Synonym: TW661

Alternate gene names: 28572802

Gene position: 753806-752772 (Counterclockwise)

Preceding gene: 28572804

Following gene: 28572801

Centisome position: 81.41

GC content: 46.18

Gene sequence:

>1035_bases
ATGGGTCTTACTGTTGGAATTGTGGGTCTGCCTAATGTTGGCAAGTCCACCCTATTTAACGCACTAACGCGCGGAAAGGC
TCTTGCAGCAAACTATCCTTTTGCAACGATAGAGCCAAATGTTGGAATTGCCCCCCTTGCAGATGCCCGGCTGGAAAAAT
TATCAACGATATTTGCTTCGGAAAAGATAATTTTTGCAACAGTTAGTTTCGTTGATATTGCAGGACTTGTTGAGGGCGCG
AGTAGGGGTGAAGGTCTTGGAAGTAAGTTTTTGGCGAATATACGTGAAGTAGACGCTATAGCACATGTCGTGAGAGTGTT
TTCTGATTCACAAGTTGTGCGTGCACAAGACACACTCGGTCCGGCTGCGGATGTTGACATAGTGAATACAGAACTTGCCT
TGGCTGATATGCAGACCCTTGAGAAAGTACTTGCAAAAAAACATCCACAGCCAACTTCCTCGCAGCCTGACCGAGTGCAG
CTACAAAAGGCTTATGATGCACTAGCGTCAAATCTTGTACCAGAGAAAATAAGCGGGTTAAATCTTTTGAGAGCAAAACC
TGTTATTTATGTGATAAACGCTGATCAGGAAGTTCTGTCGGATACTGCAGCCCGTGCGCAGATTGAGTCTGCCTTTAGTC
CATGCGTGTTTCTTGATGCTAAATTTGAATCTGACCTAGCGGAGCTTGATGACAAAACCGCACTTGAGTTGCGCGAACTT
TCAGGTAACGAGTCATGTCTTGATACATTTGTTGCGGCGAGTTTTTCTGCCCTGCAACTTCAGACCTTTTTTACCGCTGG
ACCGAAGGAAGCAAGGGCATGGACCATAAAACAGCTAACAAAGGCCCCTCAGGCTGCGGGTGTTATACACAGTGATTTTG
AAAAGAAGTTTATTAGGGCAGAAATTATTTCATGCACCGACCTGTTTGAATGCGGTTCAATGAATGCTGCGCGTGCCCTC
GGCAAGGTCAGGCTTGAAGGAAGAGATTACGTCATGCATGATGGTGATGTTGTTGAGTTCCGTCACGCCGCGTGA

Upstream 100 bases:

>100_bases
TAAGACGGTTAAGATAAACAGCCAAATATCCACAAAGGTATTTTTCCAGAAGGTTTCATGAAAGGTTGTATTACCGCTCT
TTCGTTCTAGTATTTTACTG

Downstream 100 bases:

>100_bases
TTTGTGTGAAATTCTAAGTATTTGACTGCTTTTGCATTAACTGTCTGTCTGCCTAGCATTTTTGTTGCACAAAACACTGT
CTAAAACACTATTTATACGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGLTVGIVGLPNVGKSTLFNALTRGKALAANYPFATIEPNVGIAPLADARLEKLSTIFASEKIIFATVSFVDIAGLVEGA
SRGEGLGSKFLANIREVDAIAHVVRVFSDSQVVRAQDTLGPAADVDIVNTELALADMQTLEKVLAKKHPQPTSSQPDRVQ
LQKAYDALASNLVPEKISGLNLLRAKPVIYVINADQEVLSDTAARAQIESAFSPCVFLDAKFESDLAELDDKTALELREL
SGNESCLDTFVAASFSALQLQTFFTAGPKEARAWTIKQLTKAPQAAGVIHSDFEKKFIRAEIISCTDLFECGSMNAARAL
GKVRLEGRDYVMHDGDVVEFRHAA

Sequences:

>Translated_344_residues
MGLTVGIVGLPNVGKSTLFNALTRGKALAANYPFATIEPNVGIAPLADARLEKLSTIFASEKIIFATVSFVDIAGLVEGA
SRGEGLGSKFLANIREVDAIAHVVRVFSDSQVVRAQDTLGPAADVDIVNTELALADMQTLEKVLAKKHPQPTSSQPDRVQ
LQKAYDALASNLVPEKISGLNLLRAKPVIYVINADQEVLSDTAARAQIESAFSPCVFLDAKFESDLAELDDKTALELREL
SGNESCLDTFVAASFSALQLQTFFTAGPKEARAWTIKQLTKAPQAAGVIHSDFEKKFIRAEIISCTDLFECGSMNAARAL
GKVRLEGRDYVMHDGDVVEFRHAA
>Mature_343_residues
GLTVGIVGLPNVGKSTLFNALTRGKALAANYPFATIEPNVGIAPLADARLEKLSTIFASEKIIFATVSFVDIAGLVEGAS
RGEGLGSKFLANIREVDAIAHVVRVFSDSQVVRAQDTLGPAADVDIVNTELALADMQTLEKVLAKKHPQPTSSQPDRVQL
QKAYDALASNLVPEKISGLNLLRAKPVIYVINADQEVLSDTAARAQIESAFSPCVFLDAKFESDLAELDDKTALELRELS
GNESCLDTFVAASFSALQLQTFFTAGPKEARAWTIKQLTKAPQAAGVIHSDFEKKFIRAEIISCTDLFECGSMNAARALG
KVRLEGRDYVMHDGDVVEFRHAA

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=364, Percent_Identity=38.1868131868132, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI58761502, Length=168, Percent_Identity=39.8809523809524, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI111955139, Length=187, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787454, Length=359, Percent_Identity=44.0111420612813, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789574, Length=104, Percent_Identity=33.6538461538462, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=36.8852459016393, Blast_Score=219, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17508313, Length=101, Percent_Identity=33.6633663366337, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552324, Length=188, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=36.7292225201072, Blast_Score=214, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=32.3759791122715, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6321649, Length=172, Percent_Identity=35.4651162790698, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=37.940379403794, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=37.940379403794, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=37.940379403794, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=35.1681957186544, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24585318, Length=138, Percent_Identity=34.7826086956522, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 36995; Mature: 36863

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTVGIVGLPNVGKSTLFNALTRGKALAANYPFATIEPNVGIAPLADARLEKLSTIFAS
CCEEEEEEECCCCCHHHHHHHHHCCCEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
EKIIFATVSFVDIAGLVEGASRGEGLGSKFLANIREVDAIAHVVRVFSDSQVVRAQDTLG
CCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCC
PAADVDIVNTELALADMQTLEKVLAKKHPQPTSSQPDRVQLQKAYDALASNLVPEKISGL
CCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCC
NLLRAKPVIYVINADQEVLSDTAARAQIESAFSPCVFLDAKFESDLAELDDKTALELREL
EEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHC
SGNESCLDTFVAASFSALQLQTFFTAGPKEARAWTIKQLTKAPQAAGVIHSDFEKKFIRA
CCCHHHHHHHHHHHHHHHEEHHHHCCCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
EIISCTDLFECGSMNAARALGKVRLEGRDYVMHDGDVVEFRHAA
HHHHHHHHHHCCCCHHHHHHHHEEECCCEEEEECCCEEEEECCC
>Mature Secondary Structure 
GLTVGIVGLPNVGKSTLFNALTRGKALAANYPFATIEPNVGIAPLADARLEKLSTIFAS
CEEEEEEECCCCCHHHHHHHHHCCCEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
EKIIFATVSFVDIAGLVEGASRGEGLGSKFLANIREVDAIAHVVRVFSDSQVVRAQDTLG
CCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCC
PAADVDIVNTELALADMQTLEKVLAKKHPQPTSSQPDRVQLQKAYDALASNLVPEKISGL
CCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCC
NLLRAKPVIYVINADQEVLSDTAARAQIESAFSPCVFLDAKFESDLAELDDKTALELREL
EEEECCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCHHHHHHHHC
SGNESCLDTFVAASFSALQLQTFFTAGPKEARAWTIKQLTKAPQAAGVIHSDFEKKFIRA
CCCHHHHHHHHHHHHHHHEEHHHHCCCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHH
EIISCTDLFECGSMNAARALGKVRLEGRDYVMHDGDVVEFRHAA
HHHHHHHHHHCCCCHHHHHHHHEEECCCEEEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]