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The map label for this gene is pdtaS [H]

Identifier: 28572795

GI number: 28572795

Start: 743942

End: 745456

Strand: Reverse

Name: pdtaS [H]

Synonym: TW651

Alternate gene names: 28572795

Gene position: 745456-743942 (Counterclockwise)

Preceding gene: 28572796

Following gene: 28572794

Centisome position: 80.51

GC content: 44.55

Gene sequence:

>1515_bases
ATGCCACTTCCTGATAATTTGTCCAAGGAGTGCAAGCTAGGTAAGCTCGAGGCTGAGTGGATAGGTCTTATCCTGAACGA
GGGTAATCTCCTTGCCGGCCTTGCAAATTCTGATGTGATCTTTTGGCTCTACAAACCTAATGGTCAATTTATTTCAGTCG
AGCATATAAGACCTCAGGGTGTATTTACCTTATTTCACAGAGATTTCGTCGGAAAAACCTGTCCAGAGACATGGGCAGGT
GCCCTGAATAAAGCCTATAGTTCTTGCAAAATGATTGATCTTGTTGAAAGCACAGACTATGGCCCTGTAAAAATTGTTGT
TACCCCTGTAAAAATGAATTACTTAGGCAGAGAAAAAAAGATAGTTCCCTTTGTGGTGACAAGCCATGGTGTTATAAGTG
ATTTTAATCAGAGTATTCAGTATGTTTACACGGAATGTGCACAGGAATTGTTTGGAATGCTTACCCGCGGCGATTTTCCC
AGATCAGACTTTCCGATCGGTTCTCACTTTGGCCTTCCAAGGCCCAATGACGGGCTTATACGACTCAATCAGGATGGCGA
TGTTATACACGCCAGCCCTAAGGCTGTGTCGGTCTTCAAAACACTTGGCATTCTGAATGAGATTGAAGGTGAGAATCTAT
CAAAGTTGGTTCTGAGTCTTGTTGAGGATAATTTCAAAACAGATGAGGCGCTTCCACTTGTTGTTTCAGGAAGAGCAGAT
TGGATTTCTGAGATCCAGGTAAGTGGAGCAAATGTTGTTTTCCGGTCAGTGCCAATCCGTGATGGAAATCGAAGAAATGG
CGCAATTGTCCTTTGTAGAGATGTAACCGCTCAGAGGTTTCAGCACACCCAATTGATGACCCGCGATGCCACAATCCGCG
AAATTCATCACAGAATCAAAAACAGCCTCCAAACAGTTGCTTCAATCCTTCGCTTACAATCCAGGCGGAGTGATTCAGAA
ATTGTCCGTGCCGAATTTGCCGATGCGGTACGCAGGATCCTCGGCGTTTCTGAAGTACATGATGCTCTTTCAAGGGATCT
TAGTGAGAATCTAAATTTTGACGATTTTTTCCCGAAGCTTGTCAAGCTAATAATAAGCCTGGCAGAACTAGACAAAAATG
GTATAGACCTCAGAATAAAAGGGAGGTTCGGCTTTCTTGACAGCAAGTATGCTGTTCCACTTATGCTTGTCCTGACGGAA
TTGGTGGCAAACGCTGTAGAGCACGGCTTTTCTGGCACACATGATCAGCTCGTTATCTACGGGCAGCGGACAGATGATGC
TATGCATGTGCTTGTGTCAGATAATGGGGTTGGAATAGATCTATCCCGTCTCGGTAAGGGCCTGGGGACTAGAATTGTAA
ATTCCATAGTTGATGCTGAATTTTCTGGGCGGATCTCATGGCATAGAAATCCGTACACTTCTGATATACCTGAGGTGTCT
GATTTACTGCCAGCTCGAGGAACAACGGTCACCCTGAGCATCCCATTTGGGCAATTGACGAGAAGTACAATCTAA

Upstream 100 bases:

>100_bases
CGTGACTCAGGTTATACCCCACACGTAACATCTGCGCAACTTTGCTTACCCACGCAGTAAGGATCATATTCAACTGCCTC
AACACGATACACTGAGGTGT

Downstream 100 bases:

>100_bases
TGCTGCTGAGTGCCCTGACCCCTTCAGTTGGTTTGCAGATTACCCTGAATACTGGCGTGGCACTAACTGTCTGTCAGTCA
AGCATGCAACCAGTGCTGTA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MPLPDNLSKECKLGKLEAEWIGLILNEGNLLAGLANSDVIFWLYKPNGQFISVEHIRPQGVFTLFHRDFVGKTCPETWAG
ALNKAYSSCKMIDLVESTDYGPVKIVVTPVKMNYLGREKKIVPFVVTSHGVISDFNQSIQYVYTECAQELFGMLTRGDFP
RSDFPIGSHFGLPRPNDGLIRLNQDGDVIHASPKAVSVFKTLGILNEIEGENLSKLVLSLVEDNFKTDEALPLVVSGRAD
WISEIQVSGANVVFRSVPIRDGNRRNGAIVLCRDVTAQRFQHTQLMTRDATIREIHHRIKNSLQTVASILRLQSRRSDSE
IVRAEFADAVRRILGVSEVHDALSRDLSENLNFDDFFPKLVKLIISLAELDKNGIDLRIKGRFGFLDSKYAVPLMLVLTE
LVANAVEHGFSGTHDQLVIYGQRTDDAMHVLVSDNGVGIDLSRLGKGLGTRIVNSIVDAEFSGRISWHRNPYTSDIPEVS
DLLPARGTTVTLSIPFGQLTRSTI

Sequences:

>Translated_504_residues
MPLPDNLSKECKLGKLEAEWIGLILNEGNLLAGLANSDVIFWLYKPNGQFISVEHIRPQGVFTLFHRDFVGKTCPETWAG
ALNKAYSSCKMIDLVESTDYGPVKIVVTPVKMNYLGREKKIVPFVVTSHGVISDFNQSIQYVYTECAQELFGMLTRGDFP
RSDFPIGSHFGLPRPNDGLIRLNQDGDVIHASPKAVSVFKTLGILNEIEGENLSKLVLSLVEDNFKTDEALPLVVSGRAD
WISEIQVSGANVVFRSVPIRDGNRRNGAIVLCRDVTAQRFQHTQLMTRDATIREIHHRIKNSLQTVASILRLQSRRSDSE
IVRAEFADAVRRILGVSEVHDALSRDLSENLNFDDFFPKLVKLIISLAELDKNGIDLRIKGRFGFLDSKYAVPLMLVLTE
LVANAVEHGFSGTHDQLVIYGQRTDDAMHVLVSDNGVGIDLSRLGKGLGTRIVNSIVDAEFSGRISWHRNPYTSDIPEVS
DLLPARGTTVTLSIPFGQLTRSTI
>Mature_503_residues
PLPDNLSKECKLGKLEAEWIGLILNEGNLLAGLANSDVIFWLYKPNGQFISVEHIRPQGVFTLFHRDFVGKTCPETWAGA
LNKAYSSCKMIDLVESTDYGPVKIVVTPVKMNYLGREKKIVPFVVTSHGVISDFNQSIQYVYTECAQELFGMLTRGDFPR
SDFPIGSHFGLPRPNDGLIRLNQDGDVIHASPKAVSVFKTLGILNEIEGENLSKLVLSLVEDNFKTDEALPLVVSGRADW
ISEIQVSGANVVFRSVPIRDGNRRNGAIVLCRDVTAQRFQHTQLMTRDATIREIHHRIKNSLQTVASILRLQSRRSDSEI
VRAEFADAVRRILGVSEVHDALSRDLSENLNFDDFFPKLVKLIISLAELDKNGIDLRIKGRFGFLDSKYAVPLMLVLTEL
VANAVEHGFSGTHDQLVIYGQRTDDAMHVLVSDNGVGIDLSRLGKGLGTRIVNSIVDAEFSGRISWHRNPYTSDIPEVSD
LLPARGTTVTLSIPFGQLTRSTI

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55994; Mature: 55863

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPDNLSKECKLGKLEAEWIGLILNEGNLLAGLANSDVIFWLYKPNGQFISVEHIRPQG
CCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCEEEEEECCCCCEEEEEEECCCC
VFTLFHRDFVGKTCPETWAGALNKAYSSCKMIDLVESTDYGPVKIVVTPVKMNYLGREKK
EEEEHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCC
IVPFVVTSHGVISDFNQSIQYVYTECAQELFGMLTRGDFPRSDFPIGSHFGLPRPNDGLI
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
RLNQDGDVIHASPKAVSVFKTLGILNEIEGENLSKLVLSLVEDNFKTDEALPLVVSGRAD
EECCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCH
WISEIQVSGANVVFRSVPIRDGNRRNGAIVLCRDVTAQRFQHTQLMTRDATIREIHHRIK
HHHHHEECCCEEEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHH
NSLQTVASILRLQSRRSDSEIVRAEFADAVRRILGVSEVHDALSRDLSENLNFDDFFPKL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHH
VKLIISLAELDKNGIDLRIKGRFGFLDSKYAVPLMLVLTELVANAVEHGFSGTHDQLVIY
HHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GQRTDDAMHVLVSDNGVGIDLSRLGKGLGTRIVNSIVDAEFSGRISWHRNPYTSDIPEVS
ECCCCCEEEEEECCCCCEEEHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHH
DLLPARGTTVTLSIPFGQLTRSTI
HHCCCCCCEEEEECCHHHHHHCCC
>Mature Secondary Structure 
PLPDNLSKECKLGKLEAEWIGLILNEGNLLAGLANSDVIFWLYKPNGQFISVEHIRPQG
CCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEECCCCEEEEEECCCCCEEEEEEECCCC
VFTLFHRDFVGKTCPETWAGALNKAYSSCKMIDLVESTDYGPVKIVVTPVKMNYLGREKK
EEEEHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCC
IVPFVVTSHGVISDFNQSIQYVYTECAQELFGMLTRGDFPRSDFPIGSHFGLPRPNDGLI
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
RLNQDGDVIHASPKAVSVFKTLGILNEIEGENLSKLVLSLVEDNFKTDEALPLVVSGRAD
EECCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCH
WISEIQVSGANVVFRSVPIRDGNRRNGAIVLCRDVTAQRFQHTQLMTRDATIREIHHRIK
HHHHHEECCCEEEEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHH
NSLQTVASILRLQSRRSDSEIVRAEFADAVRRILGVSEVHDALSRDLSENLNFDDFFPKL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHH
VKLIISLAELDKNGIDLRIKGRFGFLDSKYAVPLMLVLTELVANAVEHGFSGTHDQLVIY
HHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GQRTDDAMHVLVSDNGVGIDLSRLGKGLGTRIVNSIVDAEFSGRISWHRNPYTSDIPEVS
ECCCCCEEEEEECCCCCEEEHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHH
DLLPARGTTVTLSIPFGQLTRSTI
HHCCCCCCEEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]