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The map label for this gene is pyc [H]

Identifier: 28572792

GI number: 28572792

Start: 738673

End: 742068

Strand: Reverse

Name: pyc [H]

Synonym: TW647

Alternate gene names: 28572792

Gene position: 742068-738673 (Counterclockwise)

Preceding gene: 28572794

Following gene: 28572791

Centisome position: 80.14

GC content: 46.58

Gene sequence:

>3396_bases
GTGTTTAAAAAGATTCTCATAGCAAACCGCGGTGAAATAGCGATCCGTATCTCCAGAGCCGCATTTGAGCGGCAGATACA
AACGGTTGCGATATATGCCCATGAGGATCGTAATAGTCTACACAGACTAAAAGCTGATGAAGCCTATCAAATAGGGCAAG
TTGGCAGCCCTGTTGCGGCTTATCTTGATGTTCACGAGATTATTCGTGTGGCACTTATGTCAAACTCTGATGCAATTCAT
CCGGGATATGGATTCTTATCAGAAAGCTATCTCCTTGCCGATGAAGCCGAAAAGAACGGAATAACTTTTATAGGCCCACC
AAAGGATGTCCTAAAAAGTGCAGGGGATAAGGTTCTGGCAAAACATATGGCGCAGGCAGCAGGCTTGCCAACCCTGAGAT
CCAGCACCGCAAGTAGCAATTATGACGAGTTACTCCGTGAGGCTGAATTATTTGAATATCCGATTTTTGTCAAGGCTGCG
AGTGGCGGTGGTGGCCGTGGAATGCGCATTGTCGAGAACAGGACGGCCTTAAAGAACTCTCTTGAGAGTGCGATTCAAGA
AGCGGCGGCATCATTTGGTGACCCGCGCGTTTTCCTGGAAACAGCTTTGGACAAACCCCGTCATATAGAAGTTCAGGTTT
TGGCAGACAAATTCGGTAACATTGTGCACTTGTTTGAGAGGGATTGCTCGCTGCAAAGGCGACATCAAAAAGTTATTGAG
ATTGCTCCCGCTCCAAATATTCCAGAATTACTCAGAACCACTCTCTATCGTGATGCAATTGCATTTGCAAAAAGCGTGAA
GTATGAAAATGCAGGCACAGTTGAATTTCTTGTTGACTCAAAGATGAATCATTACTTCATTGAAATGAACCCCAGGATTC
AGGTTGAGCATACTGTTACCGAAGAAATAACCGATATTGATATAGTTCAGAGTCAAATTCGTATTGCTGCCGGCGCCAGT
CTTGACGATATTGGGCTTGTTCAAGACAAAATAGAACGAAGGGGCTTTGCACTGCAATGCAGAATTACAACAGAAGATCC
CCATGCAAACTTTAGACCGGACACTGGGCGTATAACCTCTTATCAATCTCCCGGCGGCGCGGGGATTCGTCTTGATGCCA
GTGCTGTAAATCCAGGGGTAGAGATAACACCTTATTTTGACTCGATGCTTGTCAAAATGACTTGCCGAGGCAATAGCTTT
GCGGATGCAACAAACAGAGCTCGTAGAGGTCTTGCCGAGTTTAGAGTTGGTGGCGTTGCAACAAATATCTCCTTCTTACG
CACATTGCTTGATAGCAGTAATTTTCTGAATGCAGATTTTGACACAACATTTATAGAGAAGAATGGATATTTACTACAAC
AATCTTTTTTGCTTGATAAGCATGATAGGTTGGTGTCTTACCTGGGACATGTAACAGTAAATAAACCGTACGGAGATCGC
CCAGAGCTTGTTGACCCGTGTTCCAAAATTGCCAACTTTTTACCTGACTCATCTGAGGTCAAGAAAAGTGTGGAGGGAAG
CAGAGATGTTCTTTTACGCCTTGGACCCCAAGGGTTTGCAAAATGGCTTTTATGCCGCAAGGGTTTAGCTGTAACTGATA
CAACATTTCGTGATGCACATCAATCCCTCCTGGCAACCCGGGTTAGAACAATAGATCTCTCCCGCGCCGCTGAGTGCACA
TCTGCCGCTTTGCCTGAACTGTTTTCTATGGAGGTCTGGGGTGGTGCTACATATGATGTAGCTCTTCGTTTTTTGTATGA
AGATCCATGGGAGAGACTTTCAAAAATACGTGAAAAGGTCGGAAGCATATGTCTGCAGATGCTTCTTCGAGGGCGCAACA
CGGTTGGATATACCCCTTACCCAGACCAGGTTACTCGCGCTTTTGTAGACGAGGCATCGGACTTGGGGATTGATATATTC
CGTATATTTGATGCGCTAAATGATGTAGACCAGATGCGCATAGCTATAGATGCGGTACAACAGACGAACAGCGTTGCCGA
AGTGGCAATCTGTTATACAGGTGACCTCCTTGATAAGCGTGAAACAGTGTACACAATTGACTATTATCTCGAGATAGCCA
AGAAAATTGTTGATGCGGGTGCGCATATTTTAGCTATAAAAGATATGGCCGGCGTCCTGCGCCCTCGCGCTGCGACACTT
CTCGTAAGCGCCCTGAAAAGGGAATTTGCCCTTCCGGTTCATTTACACACACACGATACTCCTGGAGGACAGCTTGCTAC
CCTTTTGGCGGCTGCGGATTCGGGTGTCGATGCGGTAGATGTTGCCAGTGGCCCCATGTCTGGCACAACCAGTCAACCCT
CCATGTCGTCCCTTGTTGCCGCCACAGATAATACAGAGCATGAAACAGGCCTTTCCCTGAGTCGTGTGAATGAATTGGAG
CCATACTGGGAAGCGGTGCGCCGGCTGTATGTTCCTTTTGAATCTGGTTTACTATCCCCAACAGGTCGCGTATACATCCA
TGAAATTCCCGGAGGTCAGCTCTCTAATCTAAAACAACAGGCAATTGCACTAGGACTTTCTGATCGATTTGAGATTATTG
AGGAAATGTATGCCTATGTCAACACACTCTTTGGGCGTATACCAAAAGTTACCCCCTCCTCCAAGGTCGTTGGGGATTTG
GCGCTTTATTTGGCTTCTGTCAATCCCGATTTGGGTGATTTTGAAATGAATCCGAAAAAATATGATATCCCGGATTCTGT
TATTTCTTTTTTAGCCGGCGAACTGGGCACTCCTCCAGCTGGTTGGCCCGATTTTAGAGACCGGGTACTGGCCGAAAGAG
AAATTAGCATTGAACAACACCCACTGAGCAGTGATGATTCAAAGAATCTTGCCACCTCGGGCAAAATACGGCAGCAAACC
CTAAGTAAACTACTTTTCCCAGAACCTTACCGCGCATTTGAAGCAAATAGGGCGGAATACGGCGACCTATCAATCTTGAG
GAGTGAAGAGTTTTTCTATGGACTTGATTTTGGCATTGAGTACAAAATAGCCGTTTCTTCATCAGTTGGCATCCTTGTGC
GTCTTGAGGCAATCGGCGGAGTTGATAGCAAGGGTGAACGATCGCTTGTACTATCAGTCAATGGTGAACTGCGCCCCATA
CAGGTAAGGGATGAATCTGCCAATGTCGAGGTCTCCCGCGCAGAAAAAGCCGACCCGAATAACCCGGGTCATATTGCCTC
CCCTTTTGCTGGGCAGGTTACAATTAAGGTCGACGTTGGCGATGAGGTTGTTTCCGGACAGGCTGTTGCGATACTTGAAG
CTATGAAGATGACCACTGTGGTCAATGCGCCAGTCTCCGGGCAGGTTATTCGCATTTCAATTCCACCGGGTCGTCAGGTG
GATATTGGCGATCTGATTATGGAAATAAGGGTCTGA

Upstream 100 bases:

>100_bases
CCCCACCCTTCAGCGAGCTAATGCTTACAACATACACTTATACAATCCAACAACACAGATTTGGTAAAACTCCAGAATGC
TTTGAGGATATCATCTAGAA

Downstream 100 bases:

>100_bases
AACATTGGAAGAATACGATCTAATCGTTGTTGGTGCTGGCAGTGGTAACAGTATTCTTGATCAGCGTTTTGATTCCCTTA
AAATCGCCCTTCTCGATGAT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1131; Mature: 1131

Protein sequence:

>1131_residues
MFKKILIANRGEIAIRISRAAFERQIQTVAIYAHEDRNSLHRLKADEAYQIGQVGSPVAAYLDVHEIIRVALMSNSDAIH
PGYGFLSESYLLADEAEKNGITFIGPPKDVLKSAGDKVLAKHMAQAAGLPTLRSSTASSNYDELLREAELFEYPIFVKAA
SGGGGRGMRIVENRTALKNSLESAIQEAAASFGDPRVFLETALDKPRHIEVQVLADKFGNIVHLFERDCSLQRRHQKVIE
IAPAPNIPELLRTTLYRDAIAFAKSVKYENAGTVEFLVDSKMNHYFIEMNPRIQVEHTVTEEITDIDIVQSQIRIAAGAS
LDDIGLVQDKIERRGFALQCRITTEDPHANFRPDTGRITSYQSPGGAGIRLDASAVNPGVEITPYFDSMLVKMTCRGNSF
ADATNRARRGLAEFRVGGVATNISFLRTLLDSSNFLNADFDTTFIEKNGYLLQQSFLLDKHDRLVSYLGHVTVNKPYGDR
PELVDPCSKIANFLPDSSEVKKSVEGSRDVLLRLGPQGFAKWLLCRKGLAVTDTTFRDAHQSLLATRVRTIDLSRAAECT
SAALPELFSMEVWGGATYDVALRFLYEDPWERLSKIREKVGSICLQMLLRGRNTVGYTPYPDQVTRAFVDEASDLGIDIF
RIFDALNDVDQMRIAIDAVQQTNSVAEVAICYTGDLLDKRETVYTIDYYLEIAKKIVDAGAHILAIKDMAGVLRPRAATL
LVSALKREFALPVHLHTHDTPGGQLATLLAAADSGVDAVDVASGPMSGTTSQPSMSSLVAATDNTEHETGLSLSRVNELE
PYWEAVRRLYVPFESGLLSPTGRVYIHEIPGGQLSNLKQQAIALGLSDRFEIIEEMYAYVNTLFGRIPKVTPSSKVVGDL
ALYLASVNPDLGDFEMNPKKYDIPDSVISFLAGELGTPPAGWPDFRDRVLAEREISIEQHPLSSDDSKNLATSGKIRQQT
LSKLLFPEPYRAFEANRAEYGDLSILRSEEFFYGLDFGIEYKIAVSSSVGILVRLEAIGGVDSKGERSLVLSVNGELRPI
QVRDESANVEVSRAEKADPNNPGHIASPFAGQVTIKVDVGDEVVSGQAVAILEAMKMTTVVNAPVSGQVIRISIPPGRQV
DIGDLIMEIRV

Sequences:

>Translated_1131_residues
MFKKILIANRGEIAIRISRAAFERQIQTVAIYAHEDRNSLHRLKADEAYQIGQVGSPVAAYLDVHEIIRVALMSNSDAIH
PGYGFLSESYLLADEAEKNGITFIGPPKDVLKSAGDKVLAKHMAQAAGLPTLRSSTASSNYDELLREAELFEYPIFVKAA
SGGGGRGMRIVENRTALKNSLESAIQEAAASFGDPRVFLETALDKPRHIEVQVLADKFGNIVHLFERDCSLQRRHQKVIE
IAPAPNIPELLRTTLYRDAIAFAKSVKYENAGTVEFLVDSKMNHYFIEMNPRIQVEHTVTEEITDIDIVQSQIRIAAGAS
LDDIGLVQDKIERRGFALQCRITTEDPHANFRPDTGRITSYQSPGGAGIRLDASAVNPGVEITPYFDSMLVKMTCRGNSF
ADATNRARRGLAEFRVGGVATNISFLRTLLDSSNFLNADFDTTFIEKNGYLLQQSFLLDKHDRLVSYLGHVTVNKPYGDR
PELVDPCSKIANFLPDSSEVKKSVEGSRDVLLRLGPQGFAKWLLCRKGLAVTDTTFRDAHQSLLATRVRTIDLSRAAECT
SAALPELFSMEVWGGATYDVALRFLYEDPWERLSKIREKVGSICLQMLLRGRNTVGYTPYPDQVTRAFVDEASDLGIDIF
RIFDALNDVDQMRIAIDAVQQTNSVAEVAICYTGDLLDKRETVYTIDYYLEIAKKIVDAGAHILAIKDMAGVLRPRAATL
LVSALKREFALPVHLHTHDTPGGQLATLLAAADSGVDAVDVASGPMSGTTSQPSMSSLVAATDNTEHETGLSLSRVNELE
PYWEAVRRLYVPFESGLLSPTGRVYIHEIPGGQLSNLKQQAIALGLSDRFEIIEEMYAYVNTLFGRIPKVTPSSKVVGDL
ALYLASVNPDLGDFEMNPKKYDIPDSVISFLAGELGTPPAGWPDFRDRVLAEREISIEQHPLSSDDSKNLATSGKIRQQT
LSKLLFPEPYRAFEANRAEYGDLSILRSEEFFYGLDFGIEYKIAVSSSVGILVRLEAIGGVDSKGERSLVLSVNGELRPI
QVRDESANVEVSRAEKADPNNPGHIASPFAGQVTIKVDVGDEVVSGQAVAILEAMKMTTVVNAPVSGQVIRISIPPGRQV
DIGDLIMEIRV
>Mature_1131_residues
MFKKILIANRGEIAIRISRAAFERQIQTVAIYAHEDRNSLHRLKADEAYQIGQVGSPVAAYLDVHEIIRVALMSNSDAIH
PGYGFLSESYLLADEAEKNGITFIGPPKDVLKSAGDKVLAKHMAQAAGLPTLRSSTASSNYDELLREAELFEYPIFVKAA
SGGGGRGMRIVENRTALKNSLESAIQEAAASFGDPRVFLETALDKPRHIEVQVLADKFGNIVHLFERDCSLQRRHQKVIE
IAPAPNIPELLRTTLYRDAIAFAKSVKYENAGTVEFLVDSKMNHYFIEMNPRIQVEHTVTEEITDIDIVQSQIRIAAGAS
LDDIGLVQDKIERRGFALQCRITTEDPHANFRPDTGRITSYQSPGGAGIRLDASAVNPGVEITPYFDSMLVKMTCRGNSF
ADATNRARRGLAEFRVGGVATNISFLRTLLDSSNFLNADFDTTFIEKNGYLLQQSFLLDKHDRLVSYLGHVTVNKPYGDR
PELVDPCSKIANFLPDSSEVKKSVEGSRDVLLRLGPQGFAKWLLCRKGLAVTDTTFRDAHQSLLATRVRTIDLSRAAECT
SAALPELFSMEVWGGATYDVALRFLYEDPWERLSKIREKVGSICLQMLLRGRNTVGYTPYPDQVTRAFVDEASDLGIDIF
RIFDALNDVDQMRIAIDAVQQTNSVAEVAICYTGDLLDKRETVYTIDYYLEIAKKIVDAGAHILAIKDMAGVLRPRAATL
LVSALKREFALPVHLHTHDTPGGQLATLLAAADSGVDAVDVASGPMSGTTSQPSMSSLVAATDNTEHETGLSLSRVNELE
PYWEAVRRLYVPFESGLLSPTGRVYIHEIPGGQLSNLKQQAIALGLSDRFEIIEEMYAYVNTLFGRIPKVTPSSKVVGDL
ALYLASVNPDLGDFEMNPKKYDIPDSVISFLAGELGTPPAGWPDFRDRVLAEREISIEQHPLSSDDSKNLATSGKIRQQT
LSKLLFPEPYRAFEANRAEYGDLSILRSEEFFYGLDFGIEYKIAVSSSVGILVRLEAIGGVDSKGERSLVLSVNGELRPI
QVRDESANVEVSRAEKADPNNPGHIASPFAGQVTIKVDVGDEVVSGQAVAILEAMKMTTVVNAPVSGQVIRISIPPGRQV
DIGDLIMEIRV

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1143, Percent_Identity=45.2318460192476, Blast_Score=948, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1143, Percent_Identity=45.2318460192476, Blast_Score=948, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1143, Percent_Identity=45.2318460192476, Blast_Score=948, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=446, Percent_Identity=44.1704035874439, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI189095269, Length=463, Percent_Identity=41.036717062635, Blast_Score=330, Evalue=5e-90,
Organism=Homo sapiens, GI65506442, Length=463, Percent_Identity=41.036717062635, Blast_Score=329, Evalue=7e-90,
Organism=Homo sapiens, GI295821183, Length=463, Percent_Identity=41.036717062635, Blast_Score=329, Evalue=8e-90,
Organism=Homo sapiens, GI134142062, Length=523, Percent_Identity=30.2103250478011, Blast_Score=212, Evalue=2e-54,
Organism=Homo sapiens, GI38679974, Length=504, Percent_Identity=30.3571428571429, Blast_Score=208, Evalue=2e-53,
Organism=Homo sapiens, GI38679960, Length=510, Percent_Identity=30.5882352941176, Blast_Score=208, Evalue=2e-53,
Organism=Homo sapiens, GI38679977, Length=504, Percent_Identity=30.3571428571429, Blast_Score=208, Evalue=2e-53,
Organism=Homo sapiens, GI38679967, Length=504, Percent_Identity=30.3571428571429, Blast_Score=208, Evalue=2e-53,
Organism=Homo sapiens, GI38679971, Length=504, Percent_Identity=30.3571428571429, Blast_Score=208, Evalue=2e-53,
Organism=Escherichia coli, GI1789654, Length=450, Percent_Identity=43.7777777777778, Blast_Score=329, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI17562816, Length=1149, Percent_Identity=44.7345517841601, Blast_Score=957, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=447, Percent_Identity=42.5055928411633, Blast_Score=334, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17567343, Length=448, Percent_Identity=41.7410714285714, Blast_Score=332, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI133931226, Length=489, Percent_Identity=32.9243353783231, Blast_Score=234, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71997163, Length=446, Percent_Identity=31.6143497757848, Blast_Score=216, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI71997168, Length=446, Percent_Identity=31.6143497757848, Blast_Score=216, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1158, Percent_Identity=46.027633851468, Blast_Score=971, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1158, Percent_Identity=46.8911917098446, Blast_Score=969, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=451, Percent_Identity=38.8026607538803, Blast_Score=320, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6323863, Length=474, Percent_Identity=31.2236286919831, Blast_Score=205, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6324343, Length=520, Percent_Identity=30, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24652212, Length=1148, Percent_Identity=43.815331010453, Blast_Score=913, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1148, Percent_Identity=43.815331010453, Blast_Score=913, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1148, Percent_Identity=43.815331010453, Blast_Score=913, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1148, Percent_Identity=43.815331010453, Blast_Score=913, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1148, Percent_Identity=43.815331010453, Blast_Score=913, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1159, Percent_Identity=43.4857635893011, Blast_Score=907, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1159, Percent_Identity=43.4857635893011, Blast_Score=907, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1159, Percent_Identity=43.4857635893011, Blast_Score=907, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1159, Percent_Identity=43.4857635893011, Blast_Score=907, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1159, Percent_Identity=43.4857635893011, Blast_Score=907, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=447, Percent_Identity=42.9530201342282, Blast_Score=351, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24651759, Length=411, Percent_Identity=42.3357664233577, Blast_Score=318, Evalue=2e-86,
Organism=Drosophila melanogaster, GI161076407, Length=498, Percent_Identity=30.1204819277108, Blast_Score=208, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24586460, Length=498, Percent_Identity=30.1204819277108, Blast_Score=208, Evalue=2e-53,
Organism=Drosophila melanogaster, GI161076409, Length=498, Percent_Identity=30.1204819277108, Blast_Score=207, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24586458, Length=498, Percent_Identity=30.1204819277108, Blast_Score=207, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 124345; Mature: 124345

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50975 ATP_GRASP ; PS00141 ASP_PROTEASE ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKILIANRGEIAIRISRAAFERQIQTVAIYAHEDRNSLHRLKADEAYQIGQVGSPVAA
CCCEEEEECCCCEEEEEEHHHHHHCEEEEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHH
YLDVHEIIRVALMSNSDAIHPGYGFLSESYLLADEAEKNGITFIGPPKDVLKSAGDKVLA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCHHHHHCCCHHHHH
KHMAQAAGLPTLRSSTASSNYDELLREAELFEYPIFVKAASGGGGRGMRIVENRTALKNS
HHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHH
LESAIQEAAASFGDPRVFLETALDKPRHIEVQVLADKFGNIVHLFERDCSLQRRHQKVIE
HHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEHHHCCCEEEHHHHCHHHHHHHHHHEE
IAPAPNIPELLRTTLYRDAIAFAKSVKYENAGTVEFLVDSKMNHYFIEMNPRIQVEHTVT
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCEEEEEEEHH
EEITDIDIVQSQIRIAAGASLDDIGLVQDKIERRGFALQCRITTEDPHANFRPDTGRITS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCEEE
YQSPGGAGIRLDASAVNPGVEITPYFDSMLVKMTCRGNSFADATNRARRGLAEFRVGGVA
ECCCCCCCEEEEHHCCCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHCHHHHHCCCHH
TNISFLRTLLDSSNFLNADFDTTFIEKNGYLLQQSFLLDKHDRLVSYLGHVTVNKPYGDR
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCEEECCCCCCC
PELVDPCSKIANFLPDSSEVKKSVEGSRDVLLRLGPQGFAKWLLCRKGLAVTDTTFRDAH
CCHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEECCHHHHHH
QSLLATRVRTIDLSRAAECTSAALPELFSMEVWGGATYDVALRFLYEDPWERLSKIREKV
HHHHHHHHHHEEHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHH
GSICLQMLLRGRNTVGYTPYPDQVTRAFVDEASDLGIDIFRIFDALNDVDQMRIAIDAVQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHH
QTNSVAEVAICYTGDLLDKRETVYTIDYYLEIAKKIVDAGAHILAIKDMAGVLRPRAATL
HCCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCHHHHH
LVSALKREFALPVHLHTHDTPGGQLATLLAAADSGVDAVDVASGPMSGTTSQPSMSSLVA
HHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHEE
ATDNTEHETGLSLSRVNELEPYWEAVRRLYVPFESGLLSPTGRVYIHEIPGGQLSNLKQQ
ECCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCCEEEEECCCCHHHHHHHH
AIALGLSDRFEIIEEMYAYVNTLFGRIPKVTPSSKVVGDLALYLASVNPDLGDFEMNPKK
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
YDIPDSVISFLAGELGTPPAGWPDFRDRVLAEREISIEQHPLSSDDSKNLATSGKIRQQT
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
LSKLLFPEPYRAFEANRAEYGDLSILRSEEFFYGLDFGIEYKIAVSSSVGILVRLEAIGG
HHHHCCCCCHHHHCCCCCCCCCEEEEECCCEEEEECCCEEEEEEECCCCCEEEEEEECCC
VDSKGERSLVLSVNGELRPIQVRDESANVEVSRAEKADPNNPGHIASPFAGQVTIKVDVG
CCCCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECC
DEVVSGQAVAILEAMKMTTVVNAPVSGQVIRISIPPGRQVDIGDLIMEIRV
CHHHCCCHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCHHHHHHEECC
>Mature Secondary Structure
MFKKILIANRGEIAIRISRAAFERQIQTVAIYAHEDRNSLHRLKADEAYQIGQVGSPVAA
CCCEEEEECCCCEEEEEEHHHHHHCEEEEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHH
YLDVHEIIRVALMSNSDAIHPGYGFLSESYLLADEAEKNGITFIGPPKDVLKSAGDKVLA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCHHHHHCCCHHHHH
KHMAQAAGLPTLRSSTASSNYDELLREAELFEYPIFVKAASGGGGRGMRIVENRTALKNS
HHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHH
LESAIQEAAASFGDPRVFLETALDKPRHIEVQVLADKFGNIVHLFERDCSLQRRHQKVIE
HHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEHHHCCCEEEHHHHCHHHHHHHHHHEE
IAPAPNIPELLRTTLYRDAIAFAKSVKYENAGTVEFLVDSKMNHYFIEMNPRIQVEHTVT
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEECCEEEEEEEHH
EEITDIDIVQSQIRIAAGASLDDIGLVQDKIERRGFALQCRITTEDPHANFRPDTGRITS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCEEE
YQSPGGAGIRLDASAVNPGVEITPYFDSMLVKMTCRGNSFADATNRARRGLAEFRVGGVA
ECCCCCCCEEEEHHCCCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHCHHHHHCCCHH
TNISFLRTLLDSSNFLNADFDTTFIEKNGYLLQQSFLLDKHDRLVSYLGHVTVNKPYGDR
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCEEECCCCCCC
PELVDPCSKIANFLPDSSEVKKSVEGSRDVLLRLGPQGFAKWLLCRKGLAVTDTTFRDAH
CCHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEECCHHHHHH
QSLLATRVRTIDLSRAAECTSAALPELFSMEVWGGATYDVALRFLYEDPWERLSKIREKV
HHHHHHHHHHEEHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHH
GSICLQMLLRGRNTVGYTPYPDQVTRAFVDEASDLGIDIFRIFDALNDVDQMRIAIDAVQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHH
QTNSVAEVAICYTGDLLDKRETVYTIDYYLEIAKKIVDAGAHILAIKDMAGVLRPRAATL
HCCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCHHHHH
LVSALKREFALPVHLHTHDTPGGQLATLLAAADSGVDAVDVASGPMSGTTSQPSMSSLVA
HHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHEE
ATDNTEHETGLSLSRVNELEPYWEAVRRLYVPFESGLLSPTGRVYIHEIPGGQLSNLKQQ
ECCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCCEEEEECCCCHHHHHHHH
AIALGLSDRFEIIEEMYAYVNTLFGRIPKVTPSSKVVGDLALYLASVNPDLGDFEMNPKK
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
YDIPDSVISFLAGELGTPPAGWPDFRDRVLAEREISIEQHPLSSDDSKNLATSGKIRQQT
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
LSKLLFPEPYRAFEANRAEYGDLSILRSEEFFYGLDFGIEYKIAVSSSVGILVRLEAIGG
HHHHCCCCCHHHHCCCCCCCCCEEEEECCCEEEEECCCEEEEEEECCCCCEEEEEEECCC
VDSKGERSLVLSVNGELRPIQVRDESANVEVSRAEKADPNNPGHIASPFAGQVTIKVDVG
CCCCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECC
DEVVSGQAVAILEAMKMTTVVNAPVSGQVIRISIPPGRQVDIGDLIMEIRV
CHHHCCCHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]