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The map label for this gene is upk

Identifier: 28572607

GI number: 28572607

Start: 494619

End: 495458

Strand: Reverse

Name: upk

Synonym: TW457

Alternate gene names: 28572607

Gene position: 495458-494619 (Counterclockwise)

Preceding gene: 28572608

Following gene: 28572606

Centisome position: 53.51

GC content: 40.71

Gene sequence:

>840_bases
TTGGTGCTTGAGGCGGTTTTGCTTGGAATTGTTCAGGGTATTACAGAATTCCTGCCTATATCCTCAACTGCCCATATGTA
CATTTTGGCGAAACTTCTAAACCTTCATGTTCCGGGGCGTTTCTTTCTTTCTTCAGTCCAGCTCGGTACTAGCTTTGCGC
TTATTTTGTATTTTTTCAAAGATGTAAAGGGCATTATTTCTGAGACCTCTAGATCTATTTATTCTTTTATTCAATTCGGT
ATTAGACAAAAACAAGAAAAACGTAATGAATACACACGATTGGGCCTTCTCCTTGTCACTGGCACAATTCCAGTTGTGCT
ATTAGGTTTTCTGCTTGTGCGCTTTGTGCCAGATGGTTTCTTCTCAGCAGCGAGAAATTTATTTACAATGGGTGTTGCAC
TTATTGTTTTCGGTCTTTTGCTTGGCTTTGCCGACGCCCTTTTTCGGCGAAAAAAGGGAAATATTTTTCAGATAACTTTT
ATCGAGTCTGTTTTAATAGGTGCGGCGCAGATTTTTGCAATCATTCCCGGAGTCAGTCGTTCCGGCATAACGATAACAAC
CGCCAGGTTCTTGAATTTTGATAGACAACTTGCGGTTCGCTTCTCTTTTTTGTTATCCCTACCAGTTACTTTTATTGGAG
GGATGTATGGGCTTGTAGCCGGCCCTGACACGGATTATTACTCCTTGGGTTATTCTCTGATTGGGGCGATTGTATCATTC
GTTGTTGGATTATTAGTTGTTAGCGCACTGTTGAGGATTATCTCAAAGACCACCTTTGTTTTGTTTGTGTATTATAGGGT
TTTGTTCGGGCTGTTTCTGGTAATTGTTTCCTTCTTTTAG

Upstream 100 bases:

>100_bases
TAGGGGTTCAAGTCCCCTCTCGCGCACGTGCGTGCCGGTGTTATTCGGATTACCGGCAGACGATGATCTTTTAGAATAAT
CTATCGGCTGGAAGGATCGA

Downstream 100 bases:

>100_bases
TTGTTTTTCCGGCGCATTCCATGGAAGCCAATTGGCCGTATACGGGGTAGCATTTGTACACATTTGAGGTGTTTGATTCA
CGGACCAGGTCTATTGTAAA

Product: undecaprenol kinase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MVLEAVLLGIVQGITEFLPISSTAHMYILAKLLNLHVPGRFFLSSVQLGTSFALILYFFKDVKGIISETSRSIYSFIQFG
IRQKQEKRNEYTRLGLLLVTGTIPVVLLGFLLVRFVPDGFFSAARNLFTMGVALIVFGLLLGFADALFRRKKGNIFQITF
IESVLIGAAQIFAIIPGVSRSGITITTARFLNFDRQLAVRFSFLLSLPVTFIGGMYGLVAGPDTDYYSLGYSLIGAIVSF
VVGLLVVSALLRIISKTTFVLFVYYRVLFGLFLVIVSFF

Sequences:

>Translated_279_residues
MVLEAVLLGIVQGITEFLPISSTAHMYILAKLLNLHVPGRFFLSSVQLGTSFALILYFFKDVKGIISETSRSIYSFIQFG
IRQKQEKRNEYTRLGLLLVTGTIPVVLLGFLLVRFVPDGFFSAARNLFTMGVALIVFGLLLGFADALFRRKKGNIFQITF
IESVLIGAAQIFAIIPGVSRSGITITTARFLNFDRQLAVRFSFLLSLPVTFIGGMYGLVAGPDTDYYSLGYSLIGAIVSF
VVGLLVVSALLRIISKTTFVLFVYYRVLFGLFLVIVSFF
>Mature_279_residues
MVLEAVLLGIVQGITEFLPISSTAHMYILAKLLNLHVPGRFFLSSVQLGTSFALILYFFKDVKGIISETSRSIYSFIQFG
IRQKQEKRNEYTRLGLLLVTGTIPVVLLGFLLVRFVPDGFFSAARNLFTMGVALIVFGLLLGFADALFRRKKGNIFQITF
IESVLIGAAQIFAIIPGVSRSGITITTARFLNFDRQLAVRFSFLLSLPVTFIGGMYGLVAGPDTDYYSLGYSLIGAIVSF
VVGLLVVSALLRIISKTTFVLFVYYRVLFGLFLVIVSFF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=277, Percent_Identity=31.7689530685921, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_TROW8 (Q83HQ7)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789387.1
- STRING:   Q83HQ7
- GeneID:   1064298
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW457
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   VHVGTLI
- ProtClustDB:   CLSK229775
- BioCyc:   TWHI218496:TW0432-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30898; Mature: 30898

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc611054)-; HASH(0xbed606c)-; HASH(0xaefabe0)-; HASH(0xc55ab98)-; HASH(0xcb1f2ac)-; HASH(0xc5acbb0)-; HASH(0xb08347c)-; HASH(0xcba89dc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLEAVLLGIVQGITEFLPISSTAHMYILAKLLNLHVPGRFFLSSVQLGTSFALILYFFK
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DVKGIISETSRSIYSFIQFGIRQKQEKRNEYTRLGLLLVTGTIPVVLLGFLLVRFVPDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FSAARNLFTMGVALIVFGLLLGFADALFRRKKGNIFQITFIESVLIGAAQIFAIIPGVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCC
SGITITTARFLNFDRQLAVRFSFLLSLPVTFIGGMYGLVAGPDTDYYSLGYSLIGAIVSF
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VVGLLVVSALLRIISKTTFVLFVYYRVLFGLFLVIVSFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MVLEAVLLGIVQGITEFLPISSTAHMYILAKLLNLHVPGRFFLSSVQLGTSFALILYFFK
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DVKGIISETSRSIYSFIQFGIRQKQEKRNEYTRLGLLLVTGTIPVVLLGFLLVRFVPDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FSAARNLFTMGVALIVFGLLLGFADALFRRKKGNIFQITFIESVLIGAAQIFAIIPGVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCC
SGITITTARFLNFDRQLAVRFSFLLSLPVTFIGGMYGLVAGPDTDYYSLGYSLIGAIVSF
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VVGLLVVSALLRIISKTTFVLFVYYRVLFGLFLVIVSFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12606174