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The map label for this gene is argS [H]

Identifier: 28572571

GI number: 28572571

Start: 456981

End: 458633

Strand: Direct

Name: argS [H]

Synonym: TW419

Alternate gene names: 28572571

Gene position: 456981-458633 (Clockwise)

Preceding gene: 28572570

Following gene: 28572572

Centisome position: 49.35

GC content: 42.04

Gene sequence:

>1653_bases
GTGGAAGATCTGAAGAAATCCGTAACCAATATTGTGCACTCAATGTATAACTTTGATTGTTCAGAAATTGTTTCACTAAC
TCGCCCACCGAAGCCTGAATACGGTGACTGGGCTTTGAGTTTACCTCTAAAACTGGCAAGCCTTCTGAAAAGTCCCGCTA
TTGATATCGCACAAAGCATCGCTTCGGCATTATTAGAGCTTGATGGGGTGCAAGATGTATATGTTGCAAAGCCTGGTTTT
ATAAATTTAAAACTCAGCCGCGAACACACTACTGGTATCATCTCAGAAGTTCTAGAGCAGGGTAGTTCTTTTGGGCGCAA
CACAACCCAGTCTAGTAAAAAAATAAATCTTGAATTCGTTTCCGGAAATCCAACCGGTCCGCTCCATCTGGCACATACTA
GATGGGCAGCTGTTGGTGATTCAATAGCTCGTATCCTTATAAACTGTGGTGCTGATGTTACGCGGGAGTATTACATCAAT
AATGTCGGCAATCAAATACATCTTTTTTCTGAGTCAGTGTACGCCCGGGCACTTTCTAAGTCTCTACCTAAAGATGGGTA
TCCGGGTGAGTATGTAAAAGATATTGCAAGAAGAATACAGTGTGAATTTCCGAATATTATTGATCTGTCATATGAAGATG
CAATCAAGATTTTTCGCAAGAGATCATGGCAGATACAAATAGAGGAAATTAAAAAGTCTTGTATAGCCTTTAGGGTCAAT
TTCGATGTTTGGTTTAGCGAGGAGTCTCTGCATGAGCCAGATCGTTTTGGAAAAAGTCAAATTGATAAGGCGCTTGCTAG
GTGTAAACAGAACGGATACCTTTTTCAAAAAAATGGGGCGTTTTTTATTCGCACAACTGAATTTGGTGATGATAAGGATC
GCGCAGTCTTGCGCTCTGACACTTCCTATACCTATTATGCTGCGGATTGCGCATATTACCTGAACAAGATCAATAGGGGC
TTTTCGGACCTTGTCATCCTGGTGGGTGCAGATCATCATGGGTATGTTAAACGTTTTCAAGCAATGTCAAACATATTTCA
TGTAGATTCTGAAAATAACCGAAAAAATGTGCAGGTTTTATTGGGACAAATGGTTTCACTAAAGAATAAACGTCAATCAA
AGAGGGAGGGTAATGTAATTGGATTATCCGAGATTATCCAATCGGTTGGCGTCGATCCACTGCGTTTTTGGTTTTGTCGT
TATCCAATAGACACACCAATTGACTTGGATGAGCAGCATCTCAAAAAGCGCAGTAATGACAATCCGGTTTACTATGTACA
GTACGCTTATGCCCGCACTCGTTCTCTTATTCGTAGCGCAAACCTATTGCAAATGGAGAAATTTGGGTTTTTTCCGGAGC
TACTGGTGCATGAAACGGAAACCGCGCTTGTGAGTTTATTGTATGATTACAAAACTGTTGTTATCGACGCGGCACGATTC
TTGCAGCCTCACAGGGTTGTGAGATATCTTGAGAGTCTTGCAGGTGCGTATCACAAATGGTACGACAAATGTAGAATAAT
CCCAAGAAAAGGTATTCTCGATAAGAGCGAGGCGGAGCTTGTAAACACCCGTCTGGAGCTCAATAGGGCAGTGGGTCAGG
TCTTATACAATGCCTTGGATTTGATTGGAGTTTCGGCGCCCGAACGCATGTGA

Upstream 100 bases:

>100_bases
AGTCTTTTTAGACCATTTTGGGTAAGCTCTTTCGTGGAGATGACAAATACTGAGGCAATTTACATAAGATGTCGAAATAA
ATAGGTTTTAGACGATGAAT

Downstream 100 bases:

>100_bases
GGGTTTTGACTCTTCCTGCGTAATATATTTGTAGTCCGGGAATTCGCTACTCAAGACGGGGGCGATAACCTTCTTTATGC
TGGTCTTGGAAGACAGTGTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MEDLKKSVTNIVHSMYNFDCSEIVSLTRPPKPEYGDWALSLPLKLASLLKSPAIDIAQSIASALLELDGVQDVYVAKPGF
INLKLSREHTTGIISEVLEQGSSFGRNTTQSSKKINLEFVSGNPTGPLHLAHTRWAAVGDSIARILINCGADVTREYYIN
NVGNQIHLFSESVYARALSKSLPKDGYPGEYVKDIARRIQCEFPNIIDLSYEDAIKIFRKRSWQIQIEEIKKSCIAFRVN
FDVWFSEESLHEPDRFGKSQIDKALARCKQNGYLFQKNGAFFIRTTEFGDDKDRAVLRSDTSYTYYAADCAYYLNKINRG
FSDLVILVGADHHGYVKRFQAMSNIFHVDSENNRKNVQVLLGQMVSLKNKRQSKREGNVIGLSEIIQSVGVDPLRFWFCR
YPIDTPIDLDEQHLKKRSNDNPVYYVQYAYARTRSLIRSANLLQMEKFGFFPELLVHETETALVSLLYDYKTVVIDAARF
LQPHRVVRYLESLAGAYHKWYDKCRIIPRKGILDKSEAELVNTRLELNRAVGQVLYNALDLIGVSAPERM

Sequences:

>Translated_550_residues
MEDLKKSVTNIVHSMYNFDCSEIVSLTRPPKPEYGDWALSLPLKLASLLKSPAIDIAQSIASALLELDGVQDVYVAKPGF
INLKLSREHTTGIISEVLEQGSSFGRNTTQSSKKINLEFVSGNPTGPLHLAHTRWAAVGDSIARILINCGADVTREYYIN
NVGNQIHLFSESVYARALSKSLPKDGYPGEYVKDIARRIQCEFPNIIDLSYEDAIKIFRKRSWQIQIEEIKKSCIAFRVN
FDVWFSEESLHEPDRFGKSQIDKALARCKQNGYLFQKNGAFFIRTTEFGDDKDRAVLRSDTSYTYYAADCAYYLNKINRG
FSDLVILVGADHHGYVKRFQAMSNIFHVDSENNRKNVQVLLGQMVSLKNKRQSKREGNVIGLSEIIQSVGVDPLRFWFCR
YPIDTPIDLDEQHLKKRSNDNPVYYVQYAYARTRSLIRSANLLQMEKFGFFPELLVHETETALVSLLYDYKTVVIDAARF
LQPHRVVRYLESLAGAYHKWYDKCRIIPRKGILDKSEAELVNTRLELNRAVGQVLYNALDLIGVSAPERM
>Mature_550_residues
MEDLKKSVTNIVHSMYNFDCSEIVSLTRPPKPEYGDWALSLPLKLASLLKSPAIDIAQSIASALLELDGVQDVYVAKPGF
INLKLSREHTTGIISEVLEQGSSFGRNTTQSSKKINLEFVSGNPTGPLHLAHTRWAAVGDSIARILINCGADVTREYYIN
NVGNQIHLFSESVYARALSKSLPKDGYPGEYVKDIARRIQCEFPNIIDLSYEDAIKIFRKRSWQIQIEEIKKSCIAFRVN
FDVWFSEESLHEPDRFGKSQIDKALARCKQNGYLFQKNGAFFIRTTEFGDDKDRAVLRSDTSYTYYAADCAYYLNKINRG
FSDLVILVGADHHGYVKRFQAMSNIFHVDSENNRKNVQVLLGQMVSLKNKRQSKREGNVIGLSEIIQSVGVDPLRFWFCR
YPIDTPIDLDEQHLKKRSNDNPVYYVQYAYARTRSLIRSANLLQMEKFGFFPELLVHETETALVSLLYDYKTVVIDAARF
LQPHRVVRYLESLAGAYHKWYDKCRIIPRKGILDKSEAELVNTRLELNRAVGQVLYNALDLIGVSAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1788184, Length=578, Percent_Identity=21.280276816609, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71985061, Length=577, Percent_Identity=22.7036395147314, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71985068, Length=536, Percent_Identity=22.9477611940299, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320548, Length=506, Percent_Identity=23.9130434782609, Blast_Score=97, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6321883, Length=621, Percent_Identity=22.866344605475, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62760; Mature: 62760

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLKKSVTNIVHSMYNFDCSEIVSLTRPPKPEYGDWALSLPLKLASLLKSPAIDIAQSI
CCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHH
ASALLELDGVQDVYVAKPGFINLKLSREHTTGIISEVLEQGSSFGRNTTQSSKKINLEFV
HHHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
SGNPTGPLHLAHTRWAAVGDSIARILINCGADVTREYYINNVGNQIHLFSESVYARALSK
CCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHH
SLPKDGYPGEYVKDIARRIQCEFPNIIDLSYEDAIKIFRKRSWQIQIEEIKKSCIAFRVN
HCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCEEEHHHHHHHHEEEEEE
FDVWFSEESLHEPDRFGKSQIDKALARCKQNGYLFQKNGAFFIRTTEFGDDKDRAVLRSD
EEEEECCCCCCCCHHCCHHHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCCEEEECC
TSYTYYAADCAYYLNKINRGFSDLVILVGADHHGYVKRFQAMSNIFHVDSENNRKNVQVL
CCEEEEHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHEECCCCCCCHHHHHH
LGQMVSLKNKRQSKREGNVIGLSEIIQSVGVDPLRFWFCRYPIDTPIDLDEQHLKKRSND
HHHHHHHHHHHHHHHCCCEECHHHHHHHHCCCHHHHHHEECCCCCCCCCCHHHHHHCCCC
NPVYYVQYAYARTRSLIRSANLLQMEKFGFFPELLVHETETALVSLLYDYKTVVIDAARF
CCEEEEEEHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQPHRVVRYLESLAGAYHKWYDKCRIIPRKGILDKSEAELVNTRLELNRAVGQVLYNALD
HCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIGVSAPERM
HHCCCCCCCC
>Mature Secondary Structure
MEDLKKSVTNIVHSMYNFDCSEIVSLTRPPKPEYGDWALSLPLKLASLLKSPAIDIAQSI
CCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHH
ASALLELDGVQDVYVAKPGFINLKLSREHTTGIISEVLEQGSSFGRNTTQSSKKINLEFV
HHHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
SGNPTGPLHLAHTRWAAVGDSIARILINCGADVTREYYINNVGNQIHLFSESVYARALSK
CCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHH
SLPKDGYPGEYVKDIARRIQCEFPNIIDLSYEDAIKIFRKRSWQIQIEEIKKSCIAFRVN
HCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCEEEHHHHHHHHEEEEEE
FDVWFSEESLHEPDRFGKSQIDKALARCKQNGYLFQKNGAFFIRTTEFGDDKDRAVLRSD
EEEEECCCCCCCCHHCCHHHHHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCCEEEECC
TSYTYYAADCAYYLNKINRGFSDLVILVGADHHGYVKRFQAMSNIFHVDSENNRKNVQVL
CCEEEEHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHEECCCCCCCHHHHHH
LGQMVSLKNKRQSKREGNVIGLSEIIQSVGVDPLRFWFCRYPIDTPIDLDEQHLKKRSND
HHHHHHHHHHHHHHHCCCEECHHHHHHHHCCCHHHHHHEECCCCCCCCCCHHHHHHCCCC
NPVYYVQYAYARTRSLIRSANLLQMEKFGFFPELLVHETETALVSLLYDYKTVVIDAARF
CCEEEEEEHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQPHRVVRYLESLAGAYHKWYDKCRIIPRKGILDKSEAELVNTRLELNRAVGQVLYNALD
HCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LIGVSAPERM
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12902375 [H]