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The map label for this gene is aroE [H]

Identifier: 28572549

GI number: 28572549

Start: 432281

End: 433228

Strand: Direct

Name: aroE [H]

Synonym: TW396

Alternate gene names: 28572549

Gene position: 432281-433228 (Clockwise)

Preceding gene: 28572548

Following gene: 28572550

Centisome position: 46.69

GC content: 45.46

Gene sequence:

>948_bases
TTGCTGTTTACAAATGCTGTTTTGGGCCTTCCGGTCTCCCATTCTTTGTCTCCAAAAATTCATTCTTTGGCATATGACCT
GTTAGGTTTACCCTTCCGGTATGTCGCAAAAGAAATGACAATCGATGGGTTCCGTGATTTTGTTTCTAAAATTATTGATG
AAGATTATCGGGGGCTTTCGGTGACCATGCCCTTGAAATTCCTCGCAGCGACCTGTGCCGATCGCCTGTCTAATCTGGTA
CGGCGCTGTGGGGCTGCAAATACTCTTGTTTTTGAGTCACACAGTGAAGAACGTGTAGGTCTTACAGATCAATATCTTTC
CAGGATCAGTCCGGATCAAAAAACATTTTTTGGCAAGTCACAGTTACTTGACCCGAACACGCAAATCCCGTCTGACTCAG
AACATATGCCAGACCCCCGGGGTTTATCCTCAAGGATCCTTGCTGCGTATAACACAGATGTGTACGGCATAATTAGGACT
ATTTTTCACTACGGCCTTGATTGCTCCGAAGTTGCTATACTGGGCTGCGGGGCAACTGCCGCATCTGTTCTGCTTGCCCT
GGAAGAGCTGTCTTGTATTGGTAACACGGTTATTTATGCAAGGAATCTATCTGCAGCAAAAAGCATGCAAAAAAAGCTTT
GCCTTGATCTTGACATTCTGCCAATTAGCACATTCAAAGGTAACTTTTCCTGTGTAATAAGCACTCTGCCATCTGACGTG
GTGTTGCCAATTCCGCGATCTGTCCGTGGCACCTTGTTTGATGTAAATTACAATCCTTGGCCGACCGGTATTGCACGCTC
TTGGCCGACCGACAGGGTGGTTTCTGGGCGTCTTATGCTTGTTGAACAAGCTATTGCCCAAATTAGCCTTTTTTGTTTTA
CTCAACTCACTCAGGAGATGGAATGTCTTCTAAGAGACACATTGTACGCAAGGATTGTGACTTGCTAG

Upstream 100 bases:

>100_bases
CACCGGCGAGACAATTTTTTCTGAAACATTTTCTGAGCATCAAAAAGGGGTTGACAAATGGCTTAGATGGCGCAAAAATC
ACCCGGATGGTAAGTGCTGA

Downstream 100 bases:

>100_bases
AGTTTCCTTTCAATGCTAGGTCCAGGTTTATTCATCCCAGGATTGCAAGTATTTTTATGACTCACTCTGAATTACCAAAT
ATCTTCGCCGGATAAGTTAC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MLFTNAVLGLPVSHSLSPKIHSLAYDLLGLPFRYVAKEMTIDGFRDFVSKIIDEDYRGLSVTMPLKFLAATCADRLSNLV
RRCGAANTLVFESHSEERVGLTDQYLSRISPDQKTFFGKSQLLDPNTQIPSDSEHMPDPRGLSSRILAAYNTDVYGIIRT
IFHYGLDCSEVAILGCGATAASVLLALEELSCIGNTVIYARNLSAAKSMQKKLCLDLDILPISTFKGNFSCVISTLPSDV
VLPIPRSVRGTLFDVNYNPWPTGIARSWPTDRVVSGRLMLVEQAIAQISLFCFTQLTQEMECLLRDTLYARIVTC

Sequences:

>Translated_315_residues
MLFTNAVLGLPVSHSLSPKIHSLAYDLLGLPFRYVAKEMTIDGFRDFVSKIIDEDYRGLSVTMPLKFLAATCADRLSNLV
RRCGAANTLVFESHSEERVGLTDQYLSRISPDQKTFFGKSQLLDPNTQIPSDSEHMPDPRGLSSRILAAYNTDVYGIIRT
IFHYGLDCSEVAILGCGATAASVLLALEELSCIGNTVIYARNLSAAKSMQKKLCLDLDILPISTFKGNFSCVISTLPSDV
VLPIPRSVRGTLFDVNYNPWPTGIARSWPTDRVVSGRLMLVEQAIAQISLFCFTQLTQEMECLLRDTLYARIVTC
>Mature_315_residues
MLFTNAVLGLPVSHSLSPKIHSLAYDLLGLPFRYVAKEMTIDGFRDFVSKIIDEDYRGLSVTMPLKFLAATCADRLSNLV
RRCGAANTLVFESHSEERVGLTDQYLSRISPDQKTFFGKSQLLDPNTQIPSDSEHMPDPRGLSSRILAAYNTDVYGIIRT
IFHYGLDCSEVAILGCGATAASVLLALEELSCIGNTVIYARNLSAAKSMQKKLCLDLDILPISTFKGNFSCVISTLPSDV
VLPIPRSVRGTLFDVNYNPWPTGIARSWPTDRVVSGRLMLVEQAIAQISLFCFTQLTQEMECLLRDTLYARIVTC

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 34832; Mature: 34832

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTNAVLGLPVSHSLSPKIHSLAYDLLGLPFRYVAKEMTIDGFRDFVSKIIDEDYRGLS
CCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VTMPLKFLAATCADRLSNLVRRCGAANTLVFESHSEERVGLTDQYLSRISPDQKTFFGKS
EEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCHHHHCCCC
QLLDPNTQIPSDSEHMPDPRGLSSRILAAYNTDVYGIIRTIFHYGLDCSEVAILGCGATA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHEEEEECCHHH
ASVLLALEELSCIGNTVIYARNLSAAKSMQKKLCLDLDILPISTFKGNFSCVISTLPSDV
HHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCE
VLPIPRSVRGTLFDVNYNPWPTGIARSWPTDRVVSGRLMLVEQAIAQISLFCFTQLTQEM
EECCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ECLLRDTLYARIVTC
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLFTNAVLGLPVSHSLSPKIHSLAYDLLGLPFRYVAKEMTIDGFRDFVSKIIDEDYRGLS
CCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VTMPLKFLAATCADRLSNLVRRCGAANTLVFESHSEERVGLTDQYLSRISPDQKTFFGKS
EEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHCCCCHHHHCCCC
QLLDPNTQIPSDSEHMPDPRGLSSRILAAYNTDVYGIIRTIFHYGLDCSEVAILGCGATA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHEEEEECCHHH
ASVLLALEELSCIGNTVIYARNLSAAKSMQKKLCLDLDILPISTFKGNFSCVISTLPSDV
HHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCE
VLPIPRSVRGTLFDVNYNPWPTGIARSWPTDRVVSGRLMLVEQAIAQISLFCFTQLTQEM
EECCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ECLLRDTLYARIVTC
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA