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The map label for this gene is nadD

Identifier: 28572452

GI number: 28572452

Start: 333790

End: 334350

Strand: Direct

Name: nadD

Synonym: TW296

Alternate gene names: 28572452

Gene position: 333790-334350 (Clockwise)

Preceding gene: 28572451

Following gene: 28572453

Centisome position: 36.05

GC content: 46.17

Gene sequence:

>561_bases
ATGGGTGGAACGTTTGATCCCATACATCACGGTCACCTTGTTGTTGCCAGTGAAGTAGCCAGTAGGTTTTGTCTTGATGA
GGTAATATTCGTCCCGACCGGTCGTCCGCCACATAAGAAGGAAGTATCTGACCCCTGGCACCGTTATCTAATGGCAGTTA
TTGCTACTGCCTCAAATCAACGTTTTTCTGTTAGCAAGATTGATATAGAAAGAACTGGACCCACTTTTACAGTTGATACC
TTGAGAGAGTTACGTGAACAACTGCAATCATCAGACCTATTCTTTATAACCGGAACAGATGCCCTCGCCAGGATTTTTTC
CTGGAAAGACGCTGATACACTTTGGTCTCTTGCGCATTTTGTAGCCGTTAGCCGCCCGGGGCATGAAGTTGTGGATATTC
CGAATGACAGGATAAGCTTCCTAGAAGTGCCCGCCATGGCGATTTCATCTTCTAATTGTCGTGAGAGGGTCAGATCCGGA
TTGCCAATTTGGTACCTTGTTCCTGAAGGGGTCGTCCAGTACATAGCAAAACACGGTTTGTATAGGAGCTTGTATGGATG
A

Upstream 100 bases:

>100_bases
TATAGAGAAACGTATGATCAGGTGTGTTCCGCTGTAAAGCGGTACGAGAGTCTCTATGACAAGCACACCAAAGACTGATA
GGGGAGCCCGGATAGGTGTT

Downstream 100 bases:

>100_bases
TAATAAGCACCTCACAAGGCGTCAGTTGAGAGAGATTTTACGCTCCACGCGCAGTGAACAGATTGATGTGCCATCTGTAA
CGCACGACTCGCCCCTGCCC

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MGGTFDPIHHGHLVVASEVASRFCLDEVIFVPTGRPPHKKEVSDPWHRYLMAVIATASNQRFSVSKIDIERTGPTFTVDT
LRELREQLQSSDLFFITGTDALARIFSWKDADTLWSLAHFVAVSRPGHEVVDIPNDRISFLEVPAMAISSSNCRERVRSG
LPIWYLVPEGVVQYIAKHGLYRSLYG

Sequences:

>Translated_186_residues
MGGTFDPIHHGHLVVASEVASRFCLDEVIFVPTGRPPHKKEVSDPWHRYLMAVIATASNQRFSVSKIDIERTGPTFTVDT
LRELREQLQSSDLFFITGTDALARIFSWKDADTLWSLAHFVAVSRPGHEVVDIPNDRISFLEVPAMAISSSNCRERVRSG
LPIWYLVPEGVVQYIAKHGLYRSLYG
>Mature_185_residues
GGTFDPIHHGHLVVASEVASRFCLDEVIFVPTGRPPHKKEVSDPWHRYLMAVIATASNQRFSVSKIDIERTGPTFTVDTL
RELREQLQSSDLFFITGTDALARIFSWKDADTLWSLAHFVAVSRPGHEVVDIPNDRISFLEVPAMAISSSNCRERVRSGL
PIWYLVPEGVVQYIAKHGLYRSLYG

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=205, Percent_Identity=32.1951219512195, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_TROW8 (Q83I10)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789232.1
- ProteinModelPortal:   Q83I10
- SMR:   Q83I10
- STRING:   Q83I10
- GeneID:   1064585
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW296
- eggNOG:   COG1057
- HOGENOM:   HBG739448
- OMA:   IFMPAGN
- PhylomeDB:   Q83I10
- ProtClustDB:   PRK00071
- BioCyc:   TWHI218496:TW0277-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 20938; Mature: 20807

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGTFDPIHHGHLVVASEVASRFCLDEVIFVPTGRPPHKKEVSDPWHRYLMAVIATASNQ
CCCCCCCCCCCCEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
RFSVSKIDIERTGPTFTVDTLRELREQLQSSDLFFITGTDALARIFSWKDADTLWSLAHF
EEEEEEEEEECCCCEEEHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCHHHHHHHHHH
VAVSRPGHEVVDIPNDRISFLEVPAMAISSSNCRERVRSGLPIWYLVPEGVVQYIAKHGL
HHHCCCCCEEEECCCCCCHHEECCHHHHCCHHHHHHHHCCCCEEEECHHHHHHHHHHHCH
YRSLYG
HHHHCC
>Mature Secondary Structure 
GGTFDPIHHGHLVVASEVASRFCLDEVIFVPTGRPPHKKEVSDPWHRYLMAVIATASNQ
CCCCCCCCCCCEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
RFSVSKIDIERTGPTFTVDTLRELREQLQSSDLFFITGTDALARIFSWKDADTLWSLAHF
EEEEEEEEEECCCCEEEHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCHHHHHHHHHH
VAVSRPGHEVVDIPNDRISFLEVPAMAISSSNCRERVRSGLPIWYLVPEGVVQYIAKHGL
HHHCCCCCEEEECCCCCCHHEECCHHHHCCHHHHHHHHCCCCEEEECHHHHHHHHHHHCH
YRSLYG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174