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The map label for this gene is ileS

Identifier: 28572443

GI number: 28572443

Start: 324081

End: 327251

Strand: Direct

Name: ileS

Synonym: TW287

Alternate gene names: 28572443

Gene position: 324081-327251 (Clockwise)

Preceding gene: 28572441

Following gene: 28572444

Centisome position: 35.0

GC content: 46.17

Gene sequence:

>3171_bases
ATGTGTGATCAAGGCGAGGTTTCTTCGCAGAACAGTTCGGATTATAAAGAACAGCGCCCTACACCACGGCCAAATCTTCC
GAAAATTGAGGAGAGTGTATTGGCCTTTTGGTCGAGCGATAAGACCTTTGAAGCCTCGCTTGAGCAAAGACAACACGGTA
AGCGGTGGGTGTTCTATGATGGCCCTCCATTTGCCAATGGCCTTCCACATTTCGGGCATTTGTTGACAGGTTATATAAAG
GATGCTATCCCTCGATATCAAACAATGCGTGGTCAGTATGTTCCACGAGTGTTCGGGTGGGACACCCACGGTTTGCCGGC
AGAGCTTGAGGCAATGAAGCGTCTCGGCATAACCGAGAAATCTCAGATTGAATCTATGGGAATTGCGAGCTTTAACGAAG
CGGCCAGAAAGTCAGTACTGACATATGTTGATCAATGGGAAGAATATGTTAACCGTCAGGCGCGATGGGTTGATTTTAAA
AACGGATACAAAACTCTCGATCTTGATTACATGGAGTCAGTTCTATGGGCTTTTAAAACCCTTTACAAAAAGGGGGTTAT
ATACGAGGGATACAAGGTTTTACCGTATTGCTGGAATGATCAAACACCCCTTAGCAACCACGAATTGCGCATGGATGATG
AAGTGTATAAACAACGCTTGGATGATTCCCTTACGGTTACTTTCCCCCTTATTGGCCAGAAGGCTAAAACGTGTGGACTC
GACGGTGTTGCAGCCCTTGCCTGGACGACAACGCCATGGACTTTACCGAGCAATATGGCTCTTATTGTTTCCCCGAATGT
CGAGTATGTTGTTGTTTCTTCTGCTCGGCAGAATTCTAATTCTGATTTTTTACTCTGCAAGTCTTCTCTTGATTCATACG
CAGAGTGTCTCGGTTATGAATCAGGGCAAGATGCCCGTGCATCAATTAGACGCACTCTCCTTGGAAAAGAAATTGAGGGT
ATCCATTACAAGCCCCTGTTTGACTATTATGCCGACTTGCATAATGCCTTCACGATACTTTCTGACAATTATGTAGATGT
TACAGAGGGAACAGGAATTGTCCATGCATCCCCAGCGCACGGTGAAGATGATAAACGAGTGTGTGATGCCTTTGGTGTGC
CAACAGTTGTGTCAATCAATGACGCTGCGTGCTTCACGGATGTTATTAGTAACTATGCGGGGATGCATATCTTTGATGCT
AATGCGGTTATACGTTCGGATTTATCACGGGATGGTCGTATTCTGCGTCACGAGTCCTATAAGCATTCGTATCCGCATTG
CTGGCGCTGCCGCAGCCCCCTTATATACAAAGCGGTTACGAGCTGGTTTTTTAGGATAACCGATTCGGTGAACAGAATGC
TTGAATTAAATCAGCAAATTAATTGGGTGCCAAAGAGTGTGAAGAACGGTCAATTTGCAAAATGGCTCTCTTCTGCAAAG
GATTGGTCAATATCTCGTACAAGATATTGGGGCACCCCTATTCCTGTTTGGAAGAGTGATAACCCAGAATATCCCAGGAT
AGATTGCTACGGATCCTTGAAAGAGTTGGAAGATGATTTTGGTATAAAGCTTACAGATTTGCATCGCCCAGAGATAGATC
GGTTAACCAGACCCAATCCCGATGATCCAACTGGCGCGTCTACCATGCGCCGTGTTCCTGACGTGCTCGATGTGTGGTTT
GATGCTGCATCAATGCCATTTGCCCAATTGCATTATCCGTTCGAAAATATCGAGCGATTCGAGGCAAACAAGAGCGCTGA
TTTTATTGTCGAATATGCTGGCCAGATAAGAGGATGGTTTTATCTTTTGCATGCCATGTCAACAGCGCTTTTTGACGGCG
TGGCGTTTAAAAACGCGATTTGTCACGGCATTGTCCTCGGCGACGATGGGCAGAAGGCATCCAAAAGCCTGCGTAATTAT
CCTGATGTTTATGACGTATTTGAGAATGAAGGGTCAGACGCCGTTCGCTGGTATCTAATTTCTAGCTCAATTTTACGCGG
CGGAAGTCTGATTGTTAGTCGAAAAAAAATTCAGGATGCGATCCGGCAGTACATTACGCCACTGTGGAGCAGCTGGTATT
TCTTTCACATTTATTCTGAGGCTGCCCGGCCAGGAGGCTATAAGGCCAGGTTTTCGGTCGACTCTCAGGATATTCTGGAT
CGCTACATTCTGTCCAAAACGGGGCTTCTGGTAGAAGATGTTACACGCTTTATGGATTCTTTTGATATGGCATCAGCCGC
ACTGCAGCTTCGTGATTTTGTTGCTGTTTTGACTAATTGGTATATCCGCCGCAGCCGTGATAGGTTCTGGGATGGCAGTG
ATACAGGTGCTTTTGACACCTTGTATACGGTGCTTGAGACTTTATGTCGGTTAGGGGCAGTATTTGTTCCGATGGTTTCT
GAGCATGTCTATAAGTGTCTTACCAACAGTCGATCCGTGCATTTGTCTGATTGGCCCGATGTGGCGACTTTTCCTAATGA
GACCGGTCTTGTTGAGACTATGGATAGGGTTCGAAAAATTTGTTCAACAGGCTTGAGCCTTAGAAAGCGCCTGGGCATAA
AGGCCCGGCAACCACTTTCCTCAGCACATATCAGGGTCGCTCAAGTGGGATCTTTGGCTCAATACAAAGACATAATATCC
GGAGAGCTAAACGTAAAAACCGTTTCAATTGAGGAGGGGTCCTGCACTCAGCGAATGCTAAAAATATTACCCCGTGTAGC
AGGTCCCAGGCTTGCAGGGGATGTTCAGACTGTTATTGCCGCGGCCCGACGTGGTGACTGGACTGACCACGACGGGCATG
TCACCGCGGGTGGTATTCCTTTGCTTGAAAATGAATACCAACTTGTTGCAGGTGCGCAAGACTCAAAAAATTCACAGCCC
TTGCCGTTTGGCGGGAGTGTAACTCTTGATACGCGTATAGACGAAACGCTGAGGTCGGAAGGTGTTGCGCGTGATACTGT
ACGACAGATCCAAATTGCACGAAAAGAAAAAGATCTGAATATTACCGATCGCATTTCCTTAGAGGTATGCGTGCCCGATG
AGCAAGTAAAGAACAATCTTCTAGCTTTCAGTGAGTTGATCTGCAAGGAGACTCTTTGCGACCGTCTTGATATTCTTGTG
AAAAAGGGTATAGACGGAATTACAGTTTCGCTGGAAAAATTTAGACAATAG

Upstream 100 bases:

>100_bases
TAGCTCTGTTGGTGCTTTGCTGAACATGTCATTGTCATAATAATGACATTGCTATGGGGATCTCATAGTATTGATCTCGA
TAGAGAAAGGTTTTCTTCAG

Downstream 100 bases:

>100_bases
CTGTGTGATACATCTATTCGGCTCGATAGCCTATTCAGTTTGTCCGCCTGAGTTTCCCTTACTGGATGATTGGAGCCTGT
AGGCCGTGTCAGAGTTTTAC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1056; Mature: 1056

Protein sequence:

>1056_residues
MCDQGEVSSQNSSDYKEQRPTPRPNLPKIEESVLAFWSSDKTFEASLEQRQHGKRWVFYDGPPFANGLPHFGHLLTGYIK
DAIPRYQTMRGQYVPRVFGWDTHGLPAELEAMKRLGITEKSQIESMGIASFNEAARKSVLTYVDQWEEYVNRQARWVDFK
NGYKTLDLDYMESVLWAFKTLYKKGVIYEGYKVLPYCWNDQTPLSNHELRMDDEVYKQRLDDSLTVTFPLIGQKAKTCGL
DGVAALAWTTTPWTLPSNMALIVSPNVEYVVVSSARQNSNSDFLLCKSSLDSYAECLGYESGQDARASIRRTLLGKEIEG
IHYKPLFDYYADLHNAFTILSDNYVDVTEGTGIVHASPAHGEDDKRVCDAFGVPTVVSINDAACFTDVISNYAGMHIFDA
NAVIRSDLSRDGRILRHESYKHSYPHCWRCRSPLIYKAVTSWFFRITDSVNRMLELNQQINWVPKSVKNGQFAKWLSSAK
DWSISRTRYWGTPIPVWKSDNPEYPRIDCYGSLKELEDDFGIKLTDLHRPEIDRLTRPNPDDPTGASTMRRVPDVLDVWF
DAASMPFAQLHYPFENIERFEANKSADFIVEYAGQIRGWFYLLHAMSTALFDGVAFKNAICHGIVLGDDGQKASKSLRNY
PDVYDVFENEGSDAVRWYLISSSILRGGSLIVSRKKIQDAIRQYITPLWSSWYFFHIYSEAARPGGYKARFSVDSQDILD
RYILSKTGLLVEDVTRFMDSFDMASAALQLRDFVAVLTNWYIRRSRDRFWDGSDTGAFDTLYTVLETLCRLGAVFVPMVS
EHVYKCLTNSRSVHLSDWPDVATFPNETGLVETMDRVRKICSTGLSLRKRLGIKARQPLSSAHIRVAQVGSLAQYKDIIS
GELNVKTVSIEEGSCTQRMLKILPRVAGPRLAGDVQTVIAAARRGDWTDHDGHVTAGGIPLLENEYQLVAGAQDSKNSQP
LPFGGSVTLDTRIDETLRSEGVARDTVRQIQIARKEKDLNITDRISLEVCVPDEQVKNNLLAFSELICKETLCDRLDILV
KKGIDGITVSLEKFRQ

Sequences:

>Translated_1056_residues
MCDQGEVSSQNSSDYKEQRPTPRPNLPKIEESVLAFWSSDKTFEASLEQRQHGKRWVFYDGPPFANGLPHFGHLLTGYIK
DAIPRYQTMRGQYVPRVFGWDTHGLPAELEAMKRLGITEKSQIESMGIASFNEAARKSVLTYVDQWEEYVNRQARWVDFK
NGYKTLDLDYMESVLWAFKTLYKKGVIYEGYKVLPYCWNDQTPLSNHELRMDDEVYKQRLDDSLTVTFPLIGQKAKTCGL
DGVAALAWTTTPWTLPSNMALIVSPNVEYVVVSSARQNSNSDFLLCKSSLDSYAECLGYESGQDARASIRRTLLGKEIEG
IHYKPLFDYYADLHNAFTILSDNYVDVTEGTGIVHASPAHGEDDKRVCDAFGVPTVVSINDAACFTDVISNYAGMHIFDA
NAVIRSDLSRDGRILRHESYKHSYPHCWRCRSPLIYKAVTSWFFRITDSVNRMLELNQQINWVPKSVKNGQFAKWLSSAK
DWSISRTRYWGTPIPVWKSDNPEYPRIDCYGSLKELEDDFGIKLTDLHRPEIDRLTRPNPDDPTGASTMRRVPDVLDVWF
DAASMPFAQLHYPFENIERFEANKSADFIVEYAGQIRGWFYLLHAMSTALFDGVAFKNAICHGIVLGDDGQKASKSLRNY
PDVYDVFENEGSDAVRWYLISSSILRGGSLIVSRKKIQDAIRQYITPLWSSWYFFHIYSEAARPGGYKARFSVDSQDILD
RYILSKTGLLVEDVTRFMDSFDMASAALQLRDFVAVLTNWYIRRSRDRFWDGSDTGAFDTLYTVLETLCRLGAVFVPMVS
EHVYKCLTNSRSVHLSDWPDVATFPNETGLVETMDRVRKICSTGLSLRKRLGIKARQPLSSAHIRVAQVGSLAQYKDIIS
GELNVKTVSIEEGSCTQRMLKILPRVAGPRLAGDVQTVIAAARRGDWTDHDGHVTAGGIPLLENEYQLVAGAQDSKNSQP
LPFGGSVTLDTRIDETLRSEGVARDTVRQIQIARKEKDLNITDRISLEVCVPDEQVKNNLLAFSELICKETLCDRLDILV
KKGIDGITVSLEKFRQ
>Mature_1056_residues
MCDQGEVSSQNSSDYKEQRPTPRPNLPKIEESVLAFWSSDKTFEASLEQRQHGKRWVFYDGPPFANGLPHFGHLLTGYIK
DAIPRYQTMRGQYVPRVFGWDTHGLPAELEAMKRLGITEKSQIESMGIASFNEAARKSVLTYVDQWEEYVNRQARWVDFK
NGYKTLDLDYMESVLWAFKTLYKKGVIYEGYKVLPYCWNDQTPLSNHELRMDDEVYKQRLDDSLTVTFPLIGQKAKTCGL
DGVAALAWTTTPWTLPSNMALIVSPNVEYVVVSSARQNSNSDFLLCKSSLDSYAECLGYESGQDARASIRRTLLGKEIEG
IHYKPLFDYYADLHNAFTILSDNYVDVTEGTGIVHASPAHGEDDKRVCDAFGVPTVVSINDAACFTDVISNYAGMHIFDA
NAVIRSDLSRDGRILRHESYKHSYPHCWRCRSPLIYKAVTSWFFRITDSVNRMLELNQQINWVPKSVKNGQFAKWLSSAK
DWSISRTRYWGTPIPVWKSDNPEYPRIDCYGSLKELEDDFGIKLTDLHRPEIDRLTRPNPDDPTGASTMRRVPDVLDVWF
DAASMPFAQLHYPFENIERFEANKSADFIVEYAGQIRGWFYLLHAMSTALFDGVAFKNAICHGIVLGDDGQKASKSLRNY
PDVYDVFENEGSDAVRWYLISSSILRGGSLIVSRKKIQDAIRQYITPLWSSWYFFHIYSEAARPGGYKARFSVDSQDILD
RYILSKTGLLVEDVTRFMDSFDMASAALQLRDFVAVLTNWYIRRSRDRFWDGSDTGAFDTLYTVLETLCRLGAVFVPMVS
EHVYKCLTNSRSVHLSDWPDVATFPNETGLVETMDRVRKICSTGLSLRKRLGIKARQPLSSAHIRVAQVGSLAQYKDIIS
GELNVKTVSIEEGSCTQRMLKILPRVAGPRLAGDVQTVIAAARRGDWTDHDGHVTAGGIPLLENEYQLVAGAQDSKNSQP
LPFGGSVTLDTRIDETLRSEGVARDTVRQIQIARKEKDLNITDRISLEVCVPDEQVKNNLLAFSELICKETLCDRLDILV
KKGIDGITVSLEKFRQ

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1034, Percent_Identity=36.2669245647969, Blast_Score=652, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1034, Percent_Identity=36.2669245647969, Blast_Score=652, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=823, Percent_Identity=27.8250303766707, Blast_Score=288, Evalue=3e-77,
Organism=Homo sapiens, GI268370297, Length=909, Percent_Identity=21.7821782178218, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI268370293, Length=909, Percent_Identity=21.7821782178218, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI268370295, Length=849, Percent_Identity=22.6148409893993, Blast_Score=139, Evalue=2e-32,
Organism=Escherichia coli, GI2367096, Length=837, Percent_Identity=26.5232974910394, Blast_Score=271, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17541896, Length=1032, Percent_Identity=36.8217054263566, Blast_Score=627, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI71980946, Length=805, Percent_Identity=25.0931677018634, Blast_Score=193, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17510661, Length=802, Percent_Identity=21.6957605985037, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1033, Percent_Identity=35.4307841239109, Blast_Score=641, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=804, Percent_Identity=25.4975124378109, Blast_Score=203, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6321531, Length=821, Percent_Identity=22.1680876979294, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574730, Length=1033, Percent_Identity=35.8180058083253, Blast_Score=626, Evalue=1e-179,
Organism=Drosophila melanogaster, GI24668547, Length=1033, Percent_Identity=35.8180058083253, Blast_Score=626, Evalue=1e-179,
Organism=Drosophila melanogaster, GI24668543, Length=1033, Percent_Identity=35.8180058083253, Blast_Score=626, Evalue=1e-179,
Organism=Drosophila melanogaster, GI281366294, Length=774, Percent_Identity=27.2609819121447, Blast_Score=239, Evalue=9e-63,
Organism=Drosophila melanogaster, GI17864482, Length=867, Percent_Identity=21.6839677047289, Blast_Score=121, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24653289, Length=867, Percent_Identity=21.6839677047289, Blast_Score=121, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355675, Length=600, Percent_Identity=21.6666666666667, Blast_Score=106, Evalue=1e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_TROW8 (Q83I16)

Other databases:

- EMBL:   BX251411
- RefSeq:   NP_789223.1
- ProteinModelPortal:   Q83I16
- SMR:   Q83I16
- STRING:   Q83I16
- GeneID:   1064576
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW287
- eggNOG:   COG0060
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- PhylomeDB:   Q83I16
- ProtClustDB:   PRK06039
- BioCyc:   TWHI218496:TW0268-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 119752; Mature: 119752

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 635-635

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDQGEVSSQNSSDYKEQRPTPRPNLPKIEESVLAFWSSDKTFEASLEQRQHGKRWVFYD
CCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEC
GPPFANGLPHFGHLLTGYIKDAIPRYQTMRGQYVPRVFGWDTHGLPAELEAMKRLGITEK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHCCCCCH
SQIESMGIASFNEAARKSVLTYVDQWEEYVNRQARWVDFKNGYKTLDLDYMESVLWAFKT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECHHHHHHHHHHHHH
LYKKGVIYEGYKVLPYCWNDQTPLSNHELRMDDEVYKQRLDDSLTVTFPLIGQKAKTCGL
HHHCCCEECCEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHCCC
DGVAALAWTTTPWTLPSNMALIVSPNVEYVVVSSARQNSNSDFLLCKSSLDSYAECLGYE
CCCEEEEEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCC
SGQDARASIRRTLLGKEIEGIHYKPLFDYYADLHNAFTILSDNYVDVTEGTGIVHASPAH
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCEEEECCCCCEEECCCCC
GEDDKRVCDAFGVPTVVSINDAACFTDVISNYAGMHIFDANAVIRSDLSRDGRILRHESY
CCCHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCEEEECCC
KHSYPHCWRCRSPLIYKAVTSWFFRITDSVNRMLELNQQINWVPKSVKNGQFAKWLSSAK
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCC
DWSISRTRYWGTPIPVWKSDNPEYPRIDCYGSLKELEDDFGIKLTDLHRPEIDRLTRPNP
CCCCCCEEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCEEEEECCCCCHHHCCCCCC
DDPTGASTMRRVPDVLDVWFDAASMPFAQLHYPFENIERFEANKSADFIVEYAGQIRGWF
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
YLLHAMSTALFDGVAFKNAICHGIVLGDDGQKASKSLRNYPDVYDVFENEGSDAVRWYLI
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCEEEEEEE
SSSILRGGSLIVSRKKIQDAIRQYITPLWSSWYFFHIYSEAARPGGYKARFSVDSQDILD
EHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCEEEEECCHHHHHH
RYILSKTGLLVEDVTRFMDSFDMASAALQLRDFVAVLTNWYIRRSRDRFWDGSDTGAFDT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
LYTVLETLCRLGAVFVPMVSEHVYKCLTNSRSVHLSDWPDVATFPNETGLVETMDRVRKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
CSTGLSLRKRLGIKARQPLSSAHIRVAQVGSLAQYKDIISGELNVKTVSIEEGSCTQRML
HHHHHHHHHHCCCCCCCCCHHHCEEHHHHCCHHHHHHHHCCCCEEEEEEECCCCHHHHHH
KILPRVAGPRLAGDVQTVIAAARRGDWTDHDGHVTAGGIPLLENEYQLVAGAQDSKNSQP
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEECCCEEEEECCCCCCCCCC
LPFGGSVTLDTRIDETLRSEGVARDTVRQIQIARKEKDLNITDRISLEVCVPDEQVKNNL
CCCCCCEEECCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHH
LAFSELICKETLCDRLDILVKKGIDGITVSLEKFRQ
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCC
>Mature Secondary Structure
MCDQGEVSSQNSSDYKEQRPTPRPNLPKIEESVLAFWSSDKTFEASLEQRQHGKRWVFYD
CCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEC
GPPFANGLPHFGHLLTGYIKDAIPRYQTMRGQYVPRVFGWDTHGLPAELEAMKRLGITEK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHCCCCCH
SQIESMGIASFNEAARKSVLTYVDQWEEYVNRQARWVDFKNGYKTLDLDYMESVLWAFKT
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECHHHHHHHHHHHHH
LYKKGVIYEGYKVLPYCWNDQTPLSNHELRMDDEVYKQRLDDSLTVTFPLIGQKAKTCGL
HHHCCCEECCEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHCCC
DGVAALAWTTTPWTLPSNMALIVSPNVEYVVVSSARQNSNSDFLLCKSSLDSYAECLGYE
CCCEEEEEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCC
SGQDARASIRRTLLGKEIEGIHYKPLFDYYADLHNAFTILSDNYVDVTEGTGIVHASPAH
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCEEEECCCCCEEECCCCC
GEDDKRVCDAFGVPTVVSINDAACFTDVISNYAGMHIFDANAVIRSDLSRDGRILRHESY
CCCHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCEEEECCC
KHSYPHCWRCRSPLIYKAVTSWFFRITDSVNRMLELNQQINWVPKSVKNGQFAKWLSSAK
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCC
DWSISRTRYWGTPIPVWKSDNPEYPRIDCYGSLKELEDDFGIKLTDLHRPEIDRLTRPNP
CCCCCCEEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCEEEEECCCCCHHHCCCCCC
DDPTGASTMRRVPDVLDVWFDAASMPFAQLHYPFENIERFEANKSADFIVEYAGQIRGWF
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
YLLHAMSTALFDGVAFKNAICHGIVLGDDGQKASKSLRNYPDVYDVFENEGSDAVRWYLI
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCEEEEEEE
SSSILRGGSLIVSRKKIQDAIRQYITPLWSSWYFFHIYSEAARPGGYKARFSVDSQDILD
EHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCEEEEECCHHHHHH
RYILSKTGLLVEDVTRFMDSFDMASAALQLRDFVAVLTNWYIRRSRDRFWDGSDTGAFDT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
LYTVLETLCRLGAVFVPMVSEHVYKCLTNSRSVHLSDWPDVATFPNETGLVETMDRVRKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
CSTGLSLRKRLGIKARQPLSSAHIRVAQVGSLAQYKDIISGELNVKTVSIEEGSCTQRML
HHHHHHHHHHCCCCCCCCCHHHCEEHHHHCCHHHHHHHHCCCCEEEEEEECCCCHHHHHH
KILPRVAGPRLAGDVQTVIAAARRGDWTDHDGHVTAGGIPLLENEYQLVAGAQDSKNSQP
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEECCCEEEEECCCCCCCCCC
LPFGGSVTLDTRIDETLRSEGVARDTVRQIQIARKEKDLNITDRISLEVCVPDEQVKNNL
CCCCCCEEECCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHH
LAFSELICKETLCDRLDILVKKGIDGITVSLEKFRQ
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12606174