| Definition | Tropheryma whipplei TW08/27, complete genome. |
|---|---|
| Accession | NC_004551 |
| Length | 925,938 |
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The map label for this gene is skfE [H]
Identifier: 28572339
GI number: 28572339
Start: 219552
End: 220313
Strand: Direct
Name: skfE [H]
Synonym: TW177
Alternate gene names: 28572339
Gene position: 219552-220313 (Clockwise)
Preceding gene: 28572338
Following gene: 28572340
Centisome position: 23.71
GC content: 47.77
Gene sequence:
>762_bases GTGGCAAAGCTTTTGGATTATATTGCCGAGTCGCGTGTAAAAAAAGGCGAGCTTCTGTTTGCTGCGGATGGCCTTTCAAA GTTCTACGGAAAAGATGCCGCCATAGAAGGTGTGAGTTTCGAGGTTAGGGCGGGTGACTGTGTCGGCCTTATAGGTCCAA ACGGTGGTGGTAAAACCACCCTCATCAACCTGATTCTCGGCTTTATGCCACCGTCCTCCGGGGCAATAGCCTTTCACTCG GTTCTAAGCACACCGACCCAGCGCGGTCTCAATACTGGGATTATGCTTGATATCCCGGCTGTTCCCTATGGCCTTAGCGT TATTCGTTATTTCTCACTTGAGGCGAGGCATAGGCAACTGAATGACAGTGATGTCTATAGGTACATAAATGATTTTGATC TTGCTTCCAAGAGAAAGAAGAGCTTCAAGTCGCTTTCCCAGGGTTGGAAGCGAAGGGTTCTTCTTGTTTGTCTTCTGATG CTGTCTCCAGAGTTCTTGGTTCTTGATGAGCCAACGAACAGTCTTGATATTGAGGGTATTACTTGGCTTAGGGAAATTAT AAAAGCCAGGACGCAGCGCGGTCTTACAACTTTTGTATCGAGCCATAATCATCATGAGCTCTCCCAGGTTGTAACCCGCA CTCTGATCCTGAAGAGGCAGCTTCGTTACAATGGTGATCTTGCAGACCTGGCCAAGGATGGTGGGGATCTTGAGAAGGCT TATTTCCGTCTTACAGATGATAGTGCGGTTCAGTATGGATAA
Upstream 100 bases:
>100_bases TTTTTGAGATTTTCTTATACAATTTGATCATTCGGTGGAACCCAGGTATGCATCTGAATTGCTATTTGGTTCGTCCGTTT GTGAATGGCAGGGGAGTGAA
Downstream 100 bases:
>100_bases TTTTAGATTTTTGTATATAGATTTCCTTAGATCTCTCAGATCTGCGTATCTTTGGGTATTCTTTTCAATCAACATTGCTC TCGTCATTTTGACCGCATTG
Product: ABC transporter ATP-binding subunit
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MAKLLDYIAESRVKKGELLFAADGLSKFYGKDAAIEGVSFEVRAGDCVGLIGPNGGGKTTLINLILGFMPPSSGAIAFHS VLSTPTQRGLNTGIMLDIPAVPYGLSVIRYFSLEARHRQLNDSDVYRYINDFDLASKRKKSFKSLSQGWKRRVLLVCLLM LSPEFLVLDEPTNSLDIEGITWLREIIKARTQRGLTTFVSSHNHHELSQVVTRTLILKRQLRYNGDLADLAKDGGDLEKA YFRLTDDSAVQYG
Sequences:
>Translated_253_residues MAKLLDYIAESRVKKGELLFAADGLSKFYGKDAAIEGVSFEVRAGDCVGLIGPNGGGKTTLINLILGFMPPSSGAIAFHS VLSTPTQRGLNTGIMLDIPAVPYGLSVIRYFSLEARHRQLNDSDVYRYINDFDLASKRKKSFKSLSQGWKRRVLLVCLLM LSPEFLVLDEPTNSLDIEGITWLREIIKARTQRGLTTFVSSHNHHELSQVVTRTLILKRQLRYNGDLADLAKDGGDLEKA YFRLTDDSAVQYG >Mature_252_residues AKLLDYIAESRVKKGELLFAADGLSKFYGKDAAIEGVSFEVRAGDCVGLIGPNGGGKTTLINLILGFMPPSSGAIAFHSV LSTPTQRGLNTGIMLDIPAVPYGLSVIRYFSLEARHRQLNDSDVYRYINDFDLASKRKKSFKSLSQGWKRRVLLVCLLML SPEFLVLDEPTNSLDIEGITWLREIIKARTQRGLTTFVSSHNHHELSQVVTRTLILKRQLRYNGDLADLAKDGGDLEKAY FRLTDDSAVQYG
Specific function: Part of the ABC transporter SkfEF involved in the export of the bacteriocin SkfA. Responsible for energy coupling to the transport system (Probable) [H]
COG id: COG1131
COG function: function code V; ABC-type multidrug transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI153792144, Length=217, Percent_Identity=28.110599078341, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI27262624, Length=221, Percent_Identity=27.6018099547511, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI27262626, Length=221, Percent_Identity=27.6018099547511, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI27477115, Length=216, Percent_Identity=28.7037037037037, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI47078218, Length=227, Percent_Identity=27.7533039647577, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI45446740, Length=227, Percent_Identity=27.7533039647577, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI27881501, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI30795238, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI105990541, Length=221, Percent_Identity=26.6968325791855, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI27436953, Length=213, Percent_Identity=26.2910798122066, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI27881506, Length=195, Percent_Identity=30.2564102564103, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI10947137, Length=195, Percent_Identity=30.2564102564103, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI31657092, Length=227, Percent_Identity=27.3127753303965, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI87081782, Length=248, Percent_Identity=30.6451612903226, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789593, Length=216, Percent_Identity=28.2407407407407, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1786319, Length=201, Percent_Identity=29.3532338308458, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1788002, Length=195, Percent_Identity=31.2820512820513, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788165, Length=212, Percent_Identity=27.3584905660377, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1787712, Length=208, Percent_Identity=27.4038461538462, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1788761, Length=214, Percent_Identity=27.1028037383178, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI2367384, Length=206, Percent_Identity=30.0970873786408, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1787041, Length=232, Percent_Identity=25, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI87081791, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI48994943, Length=255, Percent_Identity=23.921568627451, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI87082268, Length=212, Percent_Identity=27.3584905660377, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI48995001, Length=225, Percent_Identity=26.2222222222222, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1789864, Length=249, Percent_Identity=23.6947791164659, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1790190, Length=204, Percent_Identity=26.9607843137255, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789751, Length=230, Percent_Identity=27.8260869565217, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1786563, Length=153, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1790739, Length=209, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1789991, Length=232, Percent_Identity=25.8620689655172, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17565586, Length=223, Percent_Identity=28.2511210762332, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17555318, Length=219, Percent_Identity=29.2237442922374, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17559834, Length=161, Percent_Identity=31.6770186335404, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI115533608, Length=213, Percent_Identity=27.2300469483568, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17510237, Length=213, Percent_Identity=27.6995305164319, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193202349, Length=181, Percent_Identity=29.8342541436464, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI25146777, Length=181, Percent_Identity=27.6243093922652, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193211017, Length=213, Percent_Identity=27.6995305164319, Blast_Score=64, Evalue=9e-11, Organism=Caenorhabditis elegans, GI212646699, Length=184, Percent_Identity=27.1739130434783, Blast_Score=64, Evalue=9e-11, Organism=Caenorhabditis elegans, GI193209708, Length=221, Percent_Identity=27.6018099547511, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6325030, Length=226, Percent_Identity=26.5486725663717, Blast_Score=69, Evalue=8e-13, Organism=Drosophila melanogaster, GI24666092, Length=217, Percent_Identity=30.4147465437788, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI28573573, Length=200, Percent_Identity=26.5, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI28573571, Length=200, Percent_Identity=26.5, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24666836, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI221512771, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24642252, Length=222, Percent_Identity=27.9279279279279, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI18859989, Length=222, Percent_Identity=27.9279279279279, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24643674, Length=206, Percent_Identity=28.6407766990291, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: =3.6.3.25 [H]
Molecular weight: Translated: 28101; Mature: 27970
Theoretical pI: Translated: 9.24; Mature: 9.24
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKLLDYIAESRVKKGELLFAADGLSKFYGKDAAIEGVSFEVRAGDCVGLIGPNGGGKTT CHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCEECCCEEEEECCCEEEEECCCCCCHHH LINLILGFMPPSSGAIAFHSVLSTPTQRGLNTGIMLDIPAVPYGLSVIRYFSLEARHRQL HHHHHHHHCCCCCCCHHHHHHHCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCC NDSDVYRYINDFDLASKRKKSFKSLSQGWKRRVLLVCLLMLSPEFLVLDEPTNSLDIEGI CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH TWLREIIKARTQRGLTTFVSSHNHHELSQVVTRTLILKRQLRYNGDLADLAKDGGDLEKA HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHH YFRLTDDSAVQYG HEEECCCCCCCCC >Mature Secondary Structure AKLLDYIAESRVKKGELLFAADGLSKFYGKDAAIEGVSFEVRAGDCVGLIGPNGGGKTT HHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCEECCCEEEEECCCEEEEECCCCCCHHH LINLILGFMPPSSGAIAFHSVLSTPTQRGLNTGIMLDIPAVPYGLSVIRYFSLEARHRQL HHHHHHHHCCCCCCCHHHHHHHCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCC NDSDVYRYINDFDLASKRKKSFKSLSQGWKRRVLLVCLLMLSPEFLVLDEPTNSLDIEGI CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH TWLREIIKARTQRGLTTFVSSHNHHELSQVVTRTLILKRQLRYNGDLADLAKDGGDLEKA HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHH YFRLTDDSAVQYG HEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]