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The map label for this gene is glmM

Identifier: 28572318

GI number: 28572318

Start: 179181

End: 180542

Strand: Direct

Name: glmM

Synonym: TW155

Alternate gene names: 28572318

Gene position: 179181-180542 (Clockwise)

Preceding gene: 28572317

Following gene: 28572320

Centisome position: 19.35

GC content: 49.12

Gene sequence:

>1362_bases
TTGGCCAGGCTGTTTGGAACAGATGGCATACGGGCGCTGGCAAATGGTGATTTGCTCACCCCAGAACTGGCCATGGCCGT
CGCCCGCGCCGCCGCCGTCGTCTTTACCCATGGCCGCGTTGCAAAAAGAAGGCAGGTCTTAGGCAAGCGACCGGTAGCTA
TTGTTGCGCGCGATCCCAGGATATCGGGTGATTTTTTGGTAGCGGCAATTTCCGCGGGTCTTGCCAGCTCTGGGGTAGAT
GTTCTCGACGCTGGGGTTATTCCAACTCCAGCCGTAGCCTTTTTGGTAAAAAACGCAAATGCTGACTTTGGATTTATGAT
ATCCGCATCTCACAACCCGGGTTACGACAATGGTGTAAAGATATTTGCCCATGGTGGGGTGAAACTGCCCGATGTAGTTG
AAGACCGCATTGAATATTTCCTGGATAAACAGAAACTGTCACCGATTGGTTCAAAGGTTGGCCGGATAACACGTTTTGTT
GATGCAGAGGATCGATACCAAATGCATTTACTGTCAACCTTGTTCACCAGAATAGACGGCGTGAAAGTAGTAATAGATTG
TGCCAATGGCGCAGCGTCTGGTGTTTCACCAGATGTATTTAAGTCTGCTGGTGCTGCGGTGAAGGTTATTTGCGCAGACC
CGAACGGCGTTAACATAAACGATGGTGTTGGCTCGGCATACCCAGAAAGACTTAGGGCAGAAGTTATTCGTAACTCCGCC
ACTCTCGGCCTTGCTTTTGACGGCGATGCTGATCGCTGCATCGCGGTTGATTCAAACGGCAACACGGTCGACGGGGATCA
GATAATGGCAATTTTGGCCAGATCAATGCAACAGCGCGGCACACTACGGAATAAAACCCTCGTTACAACCATTATGAGCA
ATATTGGCCTTGATCGCGCCATGAAAAAACTCGGTATCAACCTTAAAAGAACGCAGGTTGGCGATAGATACGTCATTGAG
GCCATGACCCAAGGGGGATTCAATATTGGCGGGGAGCAAAGCGGCCATATAATCCTATCTGATTATTCAACCGCCGGTGA
CGGCATTCTTGCGGGCCTGCATCTATGTGCGGAAATCATTCGAACCGGTAAAAGCTTGACGGATCTAGCTAGCATCATGG
AGATTGTCCCGCAGGTCACGGCAAACATAGAAACAGATGATCCAACAACCCTGCTGAACAACAAAAAAATTCGCCATGAG
ATATCACGCATTGAAAAATCTCTAAAGGGTAGAGTTGTAATTCGTCCAAGTGGCACAGAACCTCTTATCCGTATTATGGT
CGAGGATTTAAATCCGGAGAAAGCGGAGCGCGCCTGCTCGCATTTAGCAGATTTTTTCAAACAGGAAATCCAGAAGAGCT
AG

Upstream 100 bases:

>100_bases
GTCTGCCGGTTTTCTAACCCGTGACAGTCGGGTGAAAGAGCGCAAAAAAGCCGGCCTGAAAAAGGCCCGCAAGGCACCTC
AGTATTCGAAGCGTTAGATA

Downstream 100 bases:

>100_bases
CTTCATTTCTGTAAAGTGTCATTTTATGTCTCGGATTTTTATACACAATAAAGTCTGCCGTATGTTTCACTGGCAAAATA
TTTTCCGTGAAGTTTTTTCG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MARLFGTDGIRALANGDLLTPELAMAVARAAAVVFTHGRVAKRRQVLGKRPVAIVARDPRISGDFLVAAISAGLASSGVD
VLDAGVIPTPAVAFLVKNANADFGFMISASHNPGYDNGVKIFAHGGVKLPDVVEDRIEYFLDKQKLSPIGSKVGRITRFV
DAEDRYQMHLLSTLFTRIDGVKVVIDCANGAASGVSPDVFKSAGAAVKVICADPNGVNINDGVGSAYPERLRAEVIRNSA
TLGLAFDGDADRCIAVDSNGNTVDGDQIMAILARSMQQRGTLRNKTLVTTIMSNIGLDRAMKKLGINLKRTQVGDRYVIE
AMTQGGFNIGGEQSGHIILSDYSTAGDGILAGLHLCAEIIRTGKSLTDLASIMEIVPQVTANIETDDPTTLLNNKKIRHE
ISRIEKSLKGRVVIRPSGTEPLIRIMVEDLNPEKAERACSHLADFFKQEIQKS

Sequences:

>Translated_453_residues
MARLFGTDGIRALANGDLLTPELAMAVARAAAVVFTHGRVAKRRQVLGKRPVAIVARDPRISGDFLVAAISAGLASSGVD
VLDAGVIPTPAVAFLVKNANADFGFMISASHNPGYDNGVKIFAHGGVKLPDVVEDRIEYFLDKQKLSPIGSKVGRITRFV
DAEDRYQMHLLSTLFTRIDGVKVVIDCANGAASGVSPDVFKSAGAAVKVICADPNGVNINDGVGSAYPERLRAEVIRNSA
TLGLAFDGDADRCIAVDSNGNTVDGDQIMAILARSMQQRGTLRNKTLVTTIMSNIGLDRAMKKLGINLKRTQVGDRYVIE
AMTQGGFNIGGEQSGHIILSDYSTAGDGILAGLHLCAEIIRTGKSLTDLASIMEIVPQVTANIETDDPTTLLNNKKIRHE
ISRIEKSLKGRVVIRPSGTEPLIRIMVEDLNPEKAERACSHLADFFKQEIQKS
>Mature_452_residues
ARLFGTDGIRALANGDLLTPELAMAVARAAAVVFTHGRVAKRRQVLGKRPVAIVARDPRISGDFLVAAISAGLASSGVDV
LDAGVIPTPAVAFLVKNANADFGFMISASHNPGYDNGVKIFAHGGVKLPDVVEDRIEYFLDKQKLSPIGSKVGRITRFVD
AEDRYQMHLLSTLFTRIDGVKVVIDCANGAASGVSPDVFKSAGAAVKVICADPNGVNINDGVGSAYPERLRAEVIRNSAT
LGLAFDGDADRCIAVDSNGNTVDGDQIMAILARSMQQRGTLRNKTLVTTIMSNIGLDRAMKKLGINLKRTQVGDRYVIEA
MTQGGFNIGGEQSGHIILSDYSTAGDGILAGLHLCAEIIRTGKSLTDLASIMEIVPQVTANIETDDPTTLLNNKKIRHEI
SRIEKSLKGRVVIRPSGTEPLIRIMVEDLNPEKAERACSHLADFFKQEIQKS

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=453, Percent_Identity=43.7086092715232, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=26.2557077625571, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_TROW8 (Q83NS5)

Other databases:

- EMBL:   BX251410
- RefSeq:   NP_789098.1
- ProteinModelPortal:   Q83NS5
- SMR:   Q83NS5
- STRING:   Q83NS5
- GeneID:   1064450
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW155
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q83NS5
- ProtClustDB:   PRK14318
- BioCyc:   TWHI218496:TW0143-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48455; Mature: 48324

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLFGTDGIRALANGDLLTPELAMAVARAAAVVFTHGRVAKRRQVLGKRPVAIVARDPR
CCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCEEEEEECCC
ISGDFLVAAISAGLASSGVDVLDAGVIPTPAVAFLVKNANADFGFMISASHNPGYDNGVK
CCCHHHHHHHHHHHCCCCCHHHCCCCCCCCHHEEEEECCCCCEEEEEECCCCCCCCCCEE
IFAHGGVKLPDVVEDRIEYFLDKQKLSPIGSKVGRITRFVDAEDRYQMHLLSTLFTRIDG
EEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VKVVIDCANGAASGVSPDVFKSAGAAVKVICADPNGVNINDGVGSAYPERLRAEVIRNSA
EEEEEECCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
TLGLAFDGDADRCIAVDSNGNTVDGDQIMAILARSMQQRGTLRNKTLVTTIMSNIGLDRA
EEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHH
MKKLGINLKRTQVGDRYVIEAMTQGGFNIGGEQSGHIILSDYSTAGDGILAGLHLCAEII
HHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
RTGKSLTDLASIMEIVPQVTANIETDDPTTLLNNKKIRHEISRIEKSLKGRVVIRPSGTE
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEECCCCC
PLIRIMVEDLNPEKAERACSHLADFFKQEIQKS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARLFGTDGIRALANGDLLTPELAMAVARAAAVVFTHGRVAKRRQVLGKRPVAIVARDPR
CCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCEEEEEECCC
ISGDFLVAAISAGLASSGVDVLDAGVIPTPAVAFLVKNANADFGFMISASHNPGYDNGVK
CCCHHHHHHHHHHHCCCCCHHHCCCCCCCCHHEEEEECCCCCEEEEEECCCCCCCCCCEE
IFAHGGVKLPDVVEDRIEYFLDKQKLSPIGSKVGRITRFVDAEDRYQMHLLSTLFTRIDG
EEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VKVVIDCANGAASGVSPDVFKSAGAAVKVICADPNGVNINDGVGSAYPERLRAEVIRNSA
EEEEEECCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
TLGLAFDGDADRCIAVDSNGNTVDGDQIMAILARSMQQRGTLRNKTLVTTIMSNIGLDRA
EEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHH
MKKLGINLKRTQVGDRYVIEAMTQGGFNIGGEQSGHIILSDYSTAGDGILAGLHLCAEII
HHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
RTGKSLTDLASIMEIVPQVTANIETDDPTTLLNNKKIRHEISRIEKSLKGRVVIRPSGTE
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEECCCCC
PLIRIMVEDLNPEKAERACSHLADFFKQEIQKS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12606174