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The map label for this gene is fepG [H]

Identifier: 28572239

GI number: 28572239

Start: 59903

End: 60937

Strand: Reverse

Name: fepG [H]

Synonym: TW069

Alternate gene names: 28572239

Gene position: 60937-59903 (Counterclockwise)

Preceding gene: 28572240

Following gene: 28572238

Centisome position: 6.58

GC content: 45.51

Gene sequence:

>1035_bases
ATGCCACAGCGGGTGGCGCTGAGAACGTATTGGACAAGTTGCAATCTCGACACTCGTGCTTTGGTGGTCGGGTCTGTTTT
TGCATCTCTATGCGTGGGATTACTGTTTCTATCAGTCAGCGTTGGCTATACGCAAACCAGCTTTGCGGATATGTGGAGTG
CATTAACTGGCAACGGAGATATCGAATTACGGCAAACAATTCTTGAATGGAGACTTCCGCGGGTGTTATCAGCAATTTTC
GTTGGATCCTCTGTTGCCCTAGCCGGAGCACTGTTTCAGTCTCTAACGAGAAACCCTCTTTGCAGTCCAGATATTATTGG
ATTCAATGCGGGTGCATTTGCCGGGGTAATAATAGCTGCAGAGCTTTTTGGTGGAGAAAGAACACCGTCAACACTTTCAG
CGCTAGCCGGTGGGTTTATTGTTGCCATTCTTGTATATTTCCTGAGCTTGACAAGAACATTTCGCGGGTTACGTTTAGTT
ATAGTCGGCATTAGCCTTAACGCAATAATCTCATCGTTCAATACCTACATGAAGTCAATTATCAATGTTGAAATCAGTCA
GAACATAAGCATATGGGGTGTTGGAAGCCTGAGCCTAATAACGTGGAGTGACGCACTGCTCTTATACCTGACCTTGATTG
CATGCGTCAGTTTGGCCGTTATTGTTATTCCTAAAATGCGAGTTCTTGAAATGGGCGATGACAATGCCGCAAGCCTGGGC
GTTTCAGCAAGAAGTACATTGACAATGATGATTGTCATTGCGGTTGTATTGACTGCGGTTTCAACGACAGTGGTTGGCCC
AATCAGTTTTGTGGCCCTTACCGCTCCGCATATCGCAAAGTTTCTTGTTGGCAGTAAGGCAATTAATATTTTCCCAACTA
TAGCTGTTGGAGGGTTCTTATTGGCCGCATCAGATCTAATTGCAAGAACAATTATCGCACCGTCGCAATTACCAACCGGG
GTCGTGACAATTGTATTTGGCGGGGCGTATCTGCTTTATCTATCTATCAGGGGAGCAAATGATTACCGTCGATAA

Upstream 100 bases:

>100_bases
TTCTAACACCAACCGGACTAGACGCTGGAGTGGTTGTGCCTTTCTTGGGTGCGCCCATTCTGATTTTCCTGTCAAGAAAG
GTAAAAGTCTTTTGAGGATC

Downstream 100 bases:

>100_bases
GCTTTCGTTTTCTTACGGAAAAAACAAGGTTCTGCACGACATAAGCATAGAGATAAAACGGGGCTCTTTTATCGCAATTA
TTGGCGCTAATGGCTGTGGC

Product: iron-siderophore uptake system integral membrane component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPQRVALRTYWTSCNLDTRALVVGSVFASLCVGLLFLSVSVGYTQTSFADMWSALTGNGDIELRQTILEWRLPRVLSAIF
VGSSVALAGALFQSLTRNPLCSPDIIGFNAGAFAGVIIAAELFGGERTPSTLSALAGGFIVAILVYFLSLTRTFRGLRLV
IVGISLNAIISSFNTYMKSIINVEISQNISIWGVGSLSLITWSDALLLYLTLIACVSLAVIVIPKMRVLEMGDDNAASLG
VSARSTLTMMIVIAVVLTAVSTTVVGPISFVALTAPHIAKFLVGSKAINIFPTIAVGGFLLAASDLIARTIIAPSQLPTG
VVTIVFGGAYLLYLSIRGANDYRR

Sequences:

>Translated_344_residues
MPQRVALRTYWTSCNLDTRALVVGSVFASLCVGLLFLSVSVGYTQTSFADMWSALTGNGDIELRQTILEWRLPRVLSAIF
VGSSVALAGALFQSLTRNPLCSPDIIGFNAGAFAGVIIAAELFGGERTPSTLSALAGGFIVAILVYFLSLTRTFRGLRLV
IVGISLNAIISSFNTYMKSIINVEISQNISIWGVGSLSLITWSDALLLYLTLIACVSLAVIVIPKMRVLEMGDDNAASLG
VSARSTLTMMIVIAVVLTAVSTTVVGPISFVALTAPHIAKFLVGSKAINIFPTIAVGGFLLAASDLIARTIIAPSQLPTG
VVTIVFGGAYLLYLSIRGANDYRR
>Mature_343_residues
PQRVALRTYWTSCNLDTRALVVGSVFASLCVGLLFLSVSVGYTQTSFADMWSALTGNGDIELRQTILEWRLPRVLSAIFV
GSSVALAGALFQSLTRNPLCSPDIIGFNAGAFAGVIIAAELFGGERTPSTLSALAGGFIVAILVYFLSLTRTFRGLRLVI
VGISLNAIISSFNTYMKSIINVEISQNISIWGVGSLSLITWSDALLLYLTLIACVSLAVIVIPKMRVLEMGDDNAASLGV
SARSTLTMMIVIAVVLTAVSTTVVGPISFVALTAPHIAKFLVGSKAINIFPTIAVGGFLLAASDLIARTIIAPSQLPTGV
VTIVFGGAYLLYLSIRGANDYRR

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=327, Percent_Identity=39.4495412844037, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1790740, Length=295, Percent_Identity=32.2033898305085, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786347, Length=305, Percent_Identity=29.1803278688525, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790741, Length=277, Percent_Identity=28.158844765343, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786805, Length=276, Percent_Identity=30.7971014492754, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788004, Length=272, Percent_Identity=28.6764705882353, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36435; Mature: 36303

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQRVALRTYWTSCNLDTRALVVGSVFASLCVGLLFLSVSVGYTQTSFADMWSALTGNGD
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
IELRQTILEWRLPRVLSAIFVGSSVALAGALFQSLTRNPLCSPDIIGFNAGAFAGVIIAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
ELFGGERTPSTLSALAGGFIVAILVYFLSLTRTFRGLRLVIVGISLNAIISSFNTYMKSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHH
INVEISQNISIWGVGSLSLITWSDALLLYLTLIACVSLAVIVIPKMRVLEMGDDNAASLG
HCEEEECCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHCC
VSARSTLTMMIVIAVVLTAVSTTVVGPISFVALTAPHIAKFLVGSKAINIFPTIAVGGFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHH
LAASDLIARTIIAPSQLPTGVVTIVFGGAYLLYLSIRGANDYRR
HHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
PQRVALRTYWTSCNLDTRALVVGSVFASLCVGLLFLSVSVGYTQTSFADMWSALTGNGD
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
IELRQTILEWRLPRVLSAIFVGSSVALAGALFQSLTRNPLCSPDIIGFNAGAFAGVIIAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
ELFGGERTPSTLSALAGGFIVAILVYFLSLTRTFRGLRLVIVGISLNAIISSFNTYMKSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHH
INVEISQNISIWGVGSLSLITWSDALLLYLTLIACVSLAVIVIPKMRVLEMGDDNAASLG
HCEEEECCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHCC
VSARSTLTMMIVIAVVLTAVSTTVVGPISFVALTAPHIAKFLVGSKAINIFPTIAVGGFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHH
LAASDLIARTIIAPSQLPTGVVTIVFGGAYLLYLSIRGANDYRR
HHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]