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The map label for this gene is leuO [H]

Identifier: 326423745

GI number: 326423745

Start: 671412

End: 672371

Strand: Reverse

Name: leuO [H]

Synonym: NA

Alternate gene names: 326423745

Gene position: 672371-671412 (Counterclockwise)

Preceding gene: 27364108

Following gene: 27364106

Centisome position: 20.49

GC content: 47.19

Gene sequence:

>960_bases
ATGTTAGATAAAAAAGATGCGATGAGCGCGATTGCCAGCTATCGAATGGAAAGTACTTTACGCGGAGTGGATCTCAACCT
ACTGACGGTATTTGATGCCGTTATGCAAGAGCAAAATATTACTCGCGCAGCACATAATTTAGGCATGTCACAGCCTGCAG
TGAGCAACGCGGTTGCTCGCTTAAAAGTGATGTTTAATGATGAGCTTTTCATGCGTCAAGGGCGTGGTATTCAACCGACC
CAGCGTGCTCGTCAATTATTTGGTCCAGTCCGCCAAGCGCTGCAATTGATCCGCAATGAATTACCAAGTTCTGTATTCCA
GCCTGAGTCTTCAACTCGTCTGTTCAAACTGGCGATTTGCAGCCCATGTGATATGCGTTTTGCACCACGCATTATGGCAG
ACATTCATAACAAAGCGCCTAATGTACAATTGCATTTGGATGCAGAGTTTGATCGCATGCTCTCTGAGCGTATGCGCTAT
CAAGAAATCGACTTTGTGATTGATTACGCACGTTTTGACGAGCAAGGCTTCTCAAGCACAGAGATCTTCAAAGATGAACT
CGTGGTTGTGACGTCTAAGCAGCATCCTCGTATTCAAGGTAAAGTGACAGAAGCGCAGTTGATGCAAGAGCGTCACGCGA
AACTGTCTCGCATTCACGGCCAACGCAGCTTCTCTGAGCAAGCGTATCGCGATCTGGATGTGGCAGCGTATTTCGAAGGC
ACAAGCTTGAGCAACGTTCTGTATGTGGTTGGTCAATCTGAGCTTGTGACGATCGCTCCTCGCTGGATTGTGGAAAATGC
GGCAAACAACGCGCAGCTACAGATTCTTGACTTCCCATTTGAAAATCGTGAAATCAGCGGTTTCTTAAGCTGGCACGAAT
CATCAGAAAAAGACAAAGGCCACATTTGGCTGCGTGATCTGCTGATGGTGACATGTGGCGAAGTGGTTGCTGCGGTATAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:
NA

Sequences:

>Translated_319_residues
MLDKKDAMSAIASYRMESTLRGVDLNLLTVFDAVMQEQNITRAAHNLGMSQPAVSNAVARLKVMFNDELFMRQGRGIQPT
QRARQLFGPVRQALQLIRNELPSSVFQPESSTRLFKLAICSPCDMRFAPRIMADIHNKAPNVQLHLDAEFDRMLSERMRY
QEIDFVIDYARFDEQGFSSTEIFKDELVVVTSKQHPRIQGKVTEAQLMQERHAKLSRIHGQRSFSEQAYRDLDVAAYFEG
TSLSNVLYVVGQSELVTIAPRWIVENAANNAQLQILDFPFENREISGFLSWHESSEKDKGHIWLRDLLMVTCGEVVAAV
>Mature_319_residues
MLDKKDAMSAIASYRMESTLRGVDLNLLTVFDAVMQEQNITRAAHNLGMSQPAVSNAVARLKVMFNDELFMRQGRGIQPT
QRARQLFGPVRQALQLIRNELPSSVFQPESSTRLFKLAICSPCDMRFAPRIMADIHNKAPNVQLHLDAEFDRMLSERMRY
QEIDFVIDYARFDEQGFSSTEIFKDELVVVTSKQHPRIQGKVTEAQLMQERHAKLSRIHGQRSFSEQAYRDLDVAAYFEG
TSLSNVLYVVGQSELVTIAPRWIVENAANNAQLQILDFPFENREISGFLSWHESSEKDKGHIWLRDLLMVTCGEVVAAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=295, Percent_Identity=52.5423728813559, Blast_Score=310, Evalue=9e-86,
Organism=Escherichia coli, GI87081766, Length=290, Percent_Identity=24.4827586206897, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786820, Length=288, Percent_Identity=23.2638888888889, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789204, Length=219, Percent_Identity=26.9406392694064, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36399; Mature: 36399

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKKDAMSAIASYRMESTLRGVDLNLLTVFDAVMQEQNITRAAHNLGMSQPAVSNAVAR
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LKVMFNDELFMRQGRGIQPTQRARQLFGPVRQALQLIRNELPSSVFQPESSTRLFKLAIC
HHHEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEC
SPCDMRFAPRIMADIHNKAPNVQLHLDAEFDRMLSERMRYQEIDFVIDYARFDEQGFSST
CCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EIFKDELVVVTSKQHPRIQGKVTEAQLMQERHAKLSRIHGQRSFSEQAYRDLDVAAYFEG
HHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEECC
TSLSNVLYVVGQSELVTIAPRWIVENAANNAQLQILDFPFENREISGFLSWHESSEKDKG
CCCCCEEEEECCCCEEEECHHHHHHCCCCCCEEEEEECCCCCCCHHHEEEECCCCCCCCC
HIWLRDLLMVTCGEVVAAV
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDKKDAMSAIASYRMESTLRGVDLNLLTVFDAVMQEQNITRAAHNLGMSQPAVSNAVAR
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LKVMFNDELFMRQGRGIQPTQRARQLFGPVRQALQLIRNELPSSVFQPESSTRLFKLAIC
HHHEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEC
SPCDMRFAPRIMADIHNKAPNVQLHLDAEFDRMLSERMRYQEIDFVIDYARFDEQGFSST
CCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EIFKDELVVVTSKQHPRIQGKVTEAQLMQERHAKLSRIHGQRSFSEQAYRDLDVAAYFEG
HHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEECC
TSLSNVLYVVGQSELVTIAPRWIVENAANNAQLQILDFPFENREISGFLSWHESSEKDKG
CCCCCEEEEECCCCEEEECHHHHHHCCCCCCEEEEEECCCCCCCHHHEEEECCCCCCCCC
HIWLRDLLMVTCGEVVAAV
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609; 3519576 [H]