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The map label for this gene is pabC [H]

Identifier: 27366277

GI number: 27366277

Start: 3071513

End: 3072316

Strand: Reverse

Name: pabC [H]

Synonym: VV1_3005

Alternate gene names: 27366277

Gene position: 3072316-3071513 (Counterclockwise)

Preceding gene: 27366279

Following gene: 326424115

Centisome position: 93.61

GC content: 46.27

Gene sequence:

>804_bases
ATGTATTGGGTCAATGGCGTTGTAGCAACGGAAGTTTCTCTCTCAGACCGATCATTCCAGTATGGTGATGGCTGCTTTAC
CACCATGAAAACATTGAATGGCCAAATCGAGCATTGGCCATTACATATTGAACGTATGGAAGCGTGCTTACAGGTTCTTT
CTATTCCTCTCCCTGATTGGGCATTGGTTGAACAGTGGCTACACCAGGCCGCGTTACCAGATGCACGAGGTGGGTTGAAA
TTGCACATTAGCCGCGGAGAAGGCGGTCGCGGTTACAGCCCCAGTGGTGTTGCTACGCCAAATGTTACCATCTCGAGTTT
TTCCTATCCTGTTCATTATTCCCAATGGCAACAACATGGTGTAGAGCTCGGTGTGTGTCAAACACCTCTCGGTATCAATC
CTATTCTTGCAGGACACAAGCATAATAATCGTCTTGAGCAAGTTCTTTGCAAAGGGGAACTCGATGCGTTGGGTTACCTA
GATGGGGTGACGATTAATGTGCAAAACCATGTGATTGAAACTACAATAGCCAATCTTTTTTGGGTTAAGAATGGTGTACT
TTTTACTCCCGATCTCACTTTGAGTGGAGTGTCCGGTGTGATGCGTCGCTTGGTGATGGGCGAAGCACAACGTCGTGCGA
TAGCGTGTCAGGAAATCAAAGCAGACTTGTCCTCTTTATTGGCGGCTGAGGAAGTATTCATGACCAACTCTTTGCTGGGT
GTTGCTCCTATCAATCAGATTCTCGAAACCCGTTACCCAATTGGTACCACAACACGATATTTTGAAGGAATTTTTAACTC
GTGA

Upstream 100 bases:

>100_bases
TTTAAGAAAATCTAACACTCATTTAGGTTTCTGAAACTTGTATTTAAACGGCTTGATGCTTAGCATTAAGCCGTTTTGTT
TTTATTGGGATATAGATAGC

Downstream 100 bases:

>100_bases
TAAAAAAAATAATAGGGCTGCTCTTTATTGCCGCGTTGATGATAGGCGTTGCTACTTTTTGGGCATATTCGCAAACCAAA
ACCTACGTTAACCAACCGCT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDWALVEQWLHQAALPDARGGLK
LHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHGVELGVCQTPLGINPILAGHKHNNRLEQVLCKGELDALGYL
DGVTINVQNHVIETTIANLFWVKNGVLFTPDLTLSGVSGVMRRLVMGEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
VAPINQILETRYPIGTTTRYFEGIFNS

Sequences:

>Translated_267_residues
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDWALVEQWLHQAALPDARGGLK
LHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHGVELGVCQTPLGINPILAGHKHNNRLEQVLCKGELDALGYL
DGVTINVQNHVIETTIANLFWVKNGVLFTPDLTLSGVSGVMRRLVMGEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
VAPINQILETRYPIGTTTRYFEGIFNS
>Mature_267_residues
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDWALVEQWLHQAALPDARGGLK
LHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHGVELGVCQTPLGINPILAGHKHNNRLEQVLCKGELDALGYL
DGVTINVQNHVIETTIANLFWVKNGVLFTPDLTLSGVSGVMRRLVMGEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
VAPINQILETRYPIGTTTRYFEGIFNS

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=261, Percent_Identity=34.8659003831418, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI48994963, Length=165, Percent_Identity=28.4848484848485, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29448; Mature: 29448

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDW
CEEECEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCH
ALVEQWLHQAALPDARGGLKLHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHG
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECEECCCCHHHHHHCC
VELGVCQTPLGINPILAGHKHNNRLEQVLCKGELDALGYLDGVTINVQNHVIETTIANLF
CEEEEECCCCCCCCEECCCCCCCHHHHHHHCCCCCHHHCCCCEEEEECHHHHHHHHHHHH
WVKNGVLFTPDLTLSGVSGVMRRLVMGEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
HHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAPINQILETRYPIGTTTRYFEGIFNS
HHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MYWVNGVVATEVSLSDRSFQYGDGCFTTMKTLNGQIEHWPLHIERMEACLQVLSIPLPDW
CEEECEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCCH
ALVEQWLHQAALPDARGGLKLHISRGEGGRGYSPSGVATPNVTISSFSYPVHYSQWQQHG
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEECEECCCCHHHHHHCC
VELGVCQTPLGINPILAGHKHNNRLEQVLCKGELDALGYLDGVTINVQNHVIETTIANLF
CEEEEECCCCCCCCEECCCCCCCHHHHHHHCCCCCHHHCCCCEEEEECHHHHHHHHHHHH
WVKNGVLFTPDLTLSGVSGVMRRLVMGEAQRRAIACQEIKADLSSLLAAEEVFMTNSLLG
HHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAPINQILETRYPIGTTTRYFEGIFNS
HHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]