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The map label for this gene is ycbL [H]

Identifier: 27366238

GI number: 27366238

Start: 3024000

End: 3024656

Strand: Reverse

Name: ycbL [H]

Synonym: VV1_2962

Alternate gene names: 27366238

Gene position: 3024656-3024000 (Counterclockwise)

Preceding gene: 326424106

Following gene: 27366236

Centisome position: 92.16

GC content: 47.79

Gene sequence:

>657_bases
ATGGCACTTAAATATCAGATTGTTCCCGTTACTCCATTTGCACAAAACTGTTCGATTGTTTGGTGTGATGACACCATGAA
AGGTATCGTCATCGACCCTGGTGGTGATGAAAAGCAACTTGCCGTGATCATCAAAGAACTGGGTGTGGAAGTGGTCAATT
TGGTATTAACCCATGGTCATTTGGATCACGTTGGCGGAACCGAGCGTCTGGCTGAAATGCTTGATGGTATCGAGATTGTT
GGTCCTCATAAGGCAGACAACTTTTGGCTACAAGGTCTGGAAGGACAAAGTCAAATGTTTGGCTTTCCGTTGACAGAGGC
GTTTGAACCAAACCAATGGCTCAATGATGGTGACGAAGTGTGTTTTGGCAATCAAGTGCTGCAAGTGCTTCATACACCTG
GGCATACTCCTGGTCACGTGGTGTTGTACAGTGAAGAAGCGCGTCGTGCGTTTGTCGGGGATGTGCTATTTAATGGCAGT
ATTGGTCGAACGGATTTCCCTCAAGGCGATTTCAATACGCTGATCGCGTCAATCAAGAATAAGCTATGGCCGCTGGGCAA
TGACGTCACCTTTATCCCAGGTCATGGCCCTGAGTCGACATTCGGGCACGAGCGTCGTACCAATCCATTCGTGGCTGACG
AAATGCCACTGTACTAA

Upstream 100 bases:

>100_bases
TATCGACACGGGTCCGGTTCGCTCTTGGTGATGGCTCACCTTGTTTTTCGACGCTTCCGGTGTCATAGTTTCGCCCAGTT
CGAAATTGACCGAGGTTGCT

Downstream 100 bases:

>100_bases
CGGTTTGTAACGTGTAAGCCAGCTAAGGAGACAACTCGTCGTGTTTCTTTGGTTGGCTTTATTGATCGGGCTCCGCCGCC
GCCAAGTAGCGCCTTGCTAG

Product: hydroxyacylglutathione hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MALKYQIVPVTPFAQNCSIVWCDDTMKGIVIDPGGDEKQLAVIIKELGVEVVNLVLTHGHLDHVGGTERLAEMLDGIEIV
GPHKADNFWLQGLEGQSQMFGFPLTEAFEPNQWLNDGDEVCFGNQVLQVLHTPGHTPGHVVLYSEEARRAFVGDVLFNGS
IGRTDFPQGDFNTLIASIKNKLWPLGNDVTFIPGHGPESTFGHERRTNPFVADEMPLY

Sequences:

>Translated_218_residues
MALKYQIVPVTPFAQNCSIVWCDDTMKGIVIDPGGDEKQLAVIIKELGVEVVNLVLTHGHLDHVGGTERLAEMLDGIEIV
GPHKADNFWLQGLEGQSQMFGFPLTEAFEPNQWLNDGDEVCFGNQVLQVLHTPGHTPGHVVLYSEEARRAFVGDVLFNGS
IGRTDFPQGDFNTLIASIKNKLWPLGNDVTFIPGHGPESTFGHERRTNPFVADEMPLY
>Mature_217_residues
ALKYQIVPVTPFAQNCSIVWCDDTMKGIVIDPGGDEKQLAVIIKELGVEVVNLVLTHGHLDHVGGTERLAEMLDGIEIVG
PHKADNFWLQGLEGQSQMFGFPLTEAFEPNQWLNDGDEVCFGNQVLQVLHTPGHTPGHVVLYSEEARRAFVGDVLFNGSI
GRTDFPQGDFNTLIASIKNKLWPLGNDVTFIPGHGPESTFGHERRTNPFVADEMPLY

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1787158, Length=216, Percent_Identity=52.7777777777778, Blast_Score=256, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17538952, Length=196, Percent_Identity=29.0816326530612, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221330176, Length=194, Percent_Identity=27.8350515463918, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24064; Mature: 23932

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKYQIVPVTPFAQNCSIVWCDDTMKGIVIDPGGDEKQLAVIIKELGVEVVNLVLTHGH
CCEEEEEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LDHVGGTERLAEMLDGIEIVGPHKADNFWLQGLEGQSQMFGFPLTEAFEPNQWLNDGDEV
CCCCCCHHHHHHHHCCEEEECCCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCE
CFGNQVLQVLHTPGHTPGHVVLYSEEARRAFVGDVLFNGSIGRTDFPQGDFNTLIASIKN
EHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHH
KLWPLGNDVTFIPGHGPESTFGHERRTNPFVADEMPLY
HCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALKYQIVPVTPFAQNCSIVWCDDTMKGIVIDPGGDEKQLAVIIKELGVEVVNLVLTHGH
CEEEEEEECCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LDHVGGTERLAEMLDGIEIVGPHKADNFWLQGLEGQSQMFGFPLTEAFEPNQWLNDGDEV
CCCCCCHHHHHHHHCCEEEECCCCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCE
CFGNQVLQVLHTPGHTPGHVVLYSEEARRAFVGDVLFNGSIGRTDFPQGDFNTLIASIKN
EHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHH
KLWPLGNDVTFIPGHGPESTFGHERRTNPFVADEMPLY
HCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]