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The map label for this gene is htpX [H]

Identifier: 27366214

GI number: 27366214

Start: 3001915

End: 3002691

Strand: Reverse

Name: htpX [H]

Synonym: VV1_2938

Alternate gene names: 27366214

Gene position: 3002691-3001915 (Counterclockwise)

Preceding gene: 27366216

Following gene: 27366213

Centisome position: 91.49

GC content: 50.19

Gene sequence:

>777_bases
ATGCAGCCAGGAAGCCTCTCAGGTTTATTGGTGATGGCTGCGGTATTTGGTTTTGGTGGTGCATTTATCTCCTTGATGAT
GTCAAAGGGAATGGCACTACGCTCTGTCGGTGGAATGGTGATCGAGAGCCCTCGTAACGAGACAGAGCACTGGTTATTGG
AAACGGTGAGTCGCCAAGCTCAGCAAGCGGGCATTGGTATGCCAACCGTTGCCATTTATGATTCGCCGGATATCAACGCG
TTTGCAACTGGGGCAAAGCGTGACGATTCGCTGGTCGCGGTTTCTACGGGTCTGCTGCACAACATGACACGTGATGAAGC
AGAAGCGGTGCTGGCGCATGAGGTGAGCCATATCGCCAATGGTGACATGGTGACCATGACGTTGATGCAGGGTGTTGTGA
ACACCTTCGTTATCTTCTTGTCTCGCTTTATTGCCAACATGGTGGCTTCTAATAACAGCGATGAAGAAGGTGAAGGTTCA
AACATGATGGTGTATTTCGCGGTTTCTATCGCGCTTGAGCTGGTGTTTGGTTTCCTCGCGAGCTTCATCACCATGTGGTA
TAGCCGTCATCGTGAATTCCATGCCGATGCGGGAGCCGCCCGTCTAGTTGGTAAAGAGAAAATGATAGCGGCTCTAGAGC
GTCTAAAAATGAGCCAAGAATCAAAACTGGATGGCACCATGATGGCATTTGGTATCAACGGTAAGCAATCTCTAACGGAA
CTGCTTATGAGCCACCCGCCACTCGATAAGCGTATCGCTGCCCTTCGCAATTTCTAA

Upstream 100 bases:

>100_bases
GGAGAAAAGTAATGAAGCGAGTCATGTGTTTTTAATTACCAACCTAGCTGTGGTTCTAGTCCTCAGCGTTGTGTTGAACA
TTGTTTATGCTGTAACTGGA

Downstream 100 bases:

>100_bases
TGATGCGACAAGTGAATCGCGAATCGATGCAAAGGTGAGTCAACTCATCAGCGAATTGGATTCGAAACAGAAAGCCTGGA
GAACTCTCTCTGGGCTTTTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEHWLLETVSRQAQQAGIGMPTVAIYDSPDINA
FATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANMVASNNSDEEGEGS
NMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIAALERLKMSQESKLDGTMMAFGINGKQSLTE
LLMSHPPLDKRIAALRNF

Sequences:

>Translated_258_residues
MQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEHWLLETVSRQAQQAGIGMPTVAIYDSPDINA
FATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANMVASNNSDEEGEGS
NMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIAALERLKMSQESKLDGTMMAFGINGKQSLTE
LLMSHPPLDKRIAALRNF
>Mature_258_residues
MQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEHWLLETVSRQAQQAGIGMPTVAIYDSPDINA
FATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANMVASNNSDEEGEGS
NMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIAALERLKMSQESKLDGTMMAFGINGKQSLTE
LLMSHPPLDKRIAALRNF

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=262, Percent_Identity=69.0839694656488, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 28005; Mature: 28005

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.8 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.8 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEHWLLETVSRQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
QQAGIGMPTVAIYDSPDINAFATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIAN
HHCCCCCCEEEEECCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
GDMVTMTLMQGVVNTFVIFLSRFIANMVASNNSDEEGEGSNMMVYFAVSIALELVFGFLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
SFITMWYSRHREFHADAGAARLVGKEKMIAALERLKMSQESKLDGTMMAFGINGKQSLTE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
LLMSHPPLDKRIAALRNF
HHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEHWLLETVSRQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
QQAGIGMPTVAIYDSPDINAFATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIAN
HHCCCCCCEEEEECCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
GDMVTMTLMQGVVNTFVIFLSRFIANMVASNNSDEEGEGSNMMVYFAVSIALELVFGFLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
SFITMWYSRHREFHADAGAARLVGKEKMIAALERLKMSQESKLDGTMMAFGINGKQSLTE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
LLMSHPPLDKRIAALRNF
HHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA