Click here to switch to the map view.

The map label for this gene is yheS [H]

Identifier: 27364722

GI number: 27364722

Start: 1309883

End: 1311805

Strand: Reverse

Name: yheS [H]

Synonym: VV1_1323

Alternate gene names: 27364722

Gene position: 1311805-1309883 (Counterclockwise)

Preceding gene: 161501828

Following gene: 27364721

Centisome position: 39.97

GC content: 49.25

Gene sequence:

>1923_bases
ATGATTACCTTTTCAGATATCCAGCTGCTGCGCGGCGGCTCTCCTCTCCTTGACCAAGCATCCGCAACGATTCATCCGGG
TGATAAAATCGGCCTTGTCGGCAAAAATGGCTGTGGTAAATCCACCCTGTTTGCCTTAATTAAAGACGAACTTTCGATTG
ATGCGGGCTCATTTAGCTCTCCTCAACATTGGGAGTTAGCTTGGGTCGCACAGGAAACGCCCGCTTTAGAACGCAGCGCC
ATTGAATATGTGATTGATGGCGATCGTGAATATCGTCAGCTTGAACGCCAGTTGGCGGAAGCCGAAGCACAAGAACAAGG
GACTCGCATTGCTGAATTGCACGGTAAAATTGAAACCATTGGCGGCTACAGCATTCGTGCACGCGCTTCAGAGCTTTTGG
ATGGTTTAGGTTTTAGCCAAGAGCAGATGCATTGGAACCTGACCCAGTTTTCGGGTGGCTGGCGCATGCGTCTCAACCTT
GCTCAAGCCCTGCTGTGTCGTTCTGATCTGTTGCTGCTTGACGAACCAACCAACCACTTAGACCTTGATGCTGTCATGTG
GCTAGAACGTTGGCTACAAAGCTACCCAGGTACTTTGATGCTGATCTCGCACGACCGTGATTTTCTCGACCCAATCGTGA
ACCGCATCGTTCACATTGAAAACCAGAAACTCAATGAGTACACCGGTAACTACTCATCATTTGAAAACCAGCGCGCTCAG
AAACTGATCCTGCAACAATCGATGTTTGAGAAGCAGCAGAAGCAGATGGCGCACATGCAAAGCTACATCGATCGTTTCCG
CTACAAGGCGTCCAAAGCACGCCAAGCGCAAAGCCGCATCAAAGCGCTGGAGAAGTTAGAAAAAGTGCTCCCCGCACAGT
TTGATAACCCATTTAGCTTTGAATTTCGTGAACCTGCCGCGCTGCCAAATCCGATCATGATGATGGATGACGTTTCTGCC
GGTTACGGTGACAACCTCATCCTCGATAAAATTCGTCTTAATCTGGTGCCAGGCAGCCGCATTGGTTTGCTCGGCCGCAA
CGGCGCTGGTAAATCAACGCTGATCAAGCTCCTCTCCGGAGAGTTGAAAGCCCAAGGTGGCGATTTGACTTACTCGCAAG
GCGTCAAAATTGGTTACTTTGCTCAACACCAATTGGAAACCTTGCATCCCGAAGAAACGCCACTGCAACACATGATGCAG
ATCGCGCCAGATAAAACCGAACAAGAACTGCGTAATTATCTGGGTAGTTTTGGTTTTCACGGTGACAAAGCACTGGAGAA
AGTGGCGCCATTTTCAGGCGGAGAAAAAGCTCGCTTAGTGTTAGCGTTGATCGTCTGGCAAAAACCAAACTTACTGCTGC
TCGACGAACCGACCAACCACCTAGACTTAGATATGCGCCAAGCGCTGACACTGGCACTGCAAACCTTTGAAGGCGCGATG
GTGATCGTCTCACACGATCGCTATTTGATCCGCGCGACCACCGATGATCTTTACCTAGTGCACGATCGCCAAGTGGCTCC
ATTTGATGGTGATCTCAATGACTACTACAAATGGCTCACTGAACAGCAAAAAGCGGAGCGTCGCGAAGCGGCCGCAGAAA
TGCCTGCCAAAGACAGCAGCAACAGTGCCGCAGCGAAAAAAGAGCAAAAGCGTCGTGAAGCCGATTTTCGTAAGTTAACC
GCACCAATTCGCAAAAAACTGACACAGTTAGAAGCGAAAATGGATAAGTTGGGCGAAGCGTTGGCAGAAGCAGAGCAGCA
ATTGTCTGATAACTCACTGTATGATGCCGAAAATAAAGCTAAACTTACTCAAGTACTGGCGCTGCAAGCACAAAGTAAAT
CCGCTCTCGAAGAGATTGAAATGGAGTGGATGGCAGAACAGGAAGTACTGGAACAGATGGAACAGGAGTTCAATAGCCAA
TGA

Upstream 100 bases:

>100_bases
CTCATATTTGCATAATGATCGACATTTATCCTCTTTCCTCCTACTATGCGCAGCAAGAAAGTGCACGAATAAACAGCATT
GATAAACTAAGCAGAACGAC

Downstream 100 bases:

>100_bases
GTTCAGAGCACGTCCAACCTTCACTTACCCTCGAAAGGCTGTGGCAATTCAGCCTACAATATTATTCGATTCGAGAAGTG
AAAGAGGCGTGCCTTGCTTT

Product: glutathione-regulated potassium-efflux system ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MITFSDIQLLRGGSPLLDQASATIHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSSPQHWELAWVAQETPALERSA
IEYVIDGDREYRQLERQLAEAEAQEQGTRIAELHGKIETIGGYSIRARASELLDGLGFSQEQMHWNLTQFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVMWLERWLQSYPGTLMLISHDRDFLDPIVNRIVHIENQKLNEYTGNYSSFENQRAQ
KLILQQSMFEKQQKQMAHMQSYIDRFRYKASKARQAQSRIKALEKLEKVLPAQFDNPFSFEFREPAALPNPIMMMDDVSA
GYGDNLILDKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELKAQGGDLTYSQGVKIGYFAQHQLETLHPEETPLQHMMQ
IAPDKTEQELRNYLGSFGFHGDKALEKVAPFSGGEKARLVLALIVWQKPNLLLLDEPTNHLDLDMRQALTLALQTFEGAM
VIVSHDRYLIRATTDDLYLVHDRQVAPFDGDLNDYYKWLTEQQKAERREAAAEMPAKDSSNSAAAKKEQKRREADFRKLT
APIRKKLTQLEAKMDKLGEALAEAEQQLSDNSLYDAENKAKLTQVLALQAQSKSALEEIEMEWMAEQEVLEQMEQEFNSQ

Sequences:

>Translated_640_residues
MITFSDIQLLRGGSPLLDQASATIHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSSPQHWELAWVAQETPALERSA
IEYVIDGDREYRQLERQLAEAEAQEQGTRIAELHGKIETIGGYSIRARASELLDGLGFSQEQMHWNLTQFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVMWLERWLQSYPGTLMLISHDRDFLDPIVNRIVHIENQKLNEYTGNYSSFENQRAQ
KLILQQSMFEKQQKQMAHMQSYIDRFRYKASKARQAQSRIKALEKLEKVLPAQFDNPFSFEFREPAALPNPIMMMDDVSA
GYGDNLILDKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELKAQGGDLTYSQGVKIGYFAQHQLETLHPEETPLQHMMQ
IAPDKTEQELRNYLGSFGFHGDKALEKVAPFSGGEKARLVLALIVWQKPNLLLLDEPTNHLDLDMRQALTLALQTFEGAM
VIVSHDRYLIRATTDDLYLVHDRQVAPFDGDLNDYYKWLTEQQKAERREAAAEMPAKDSSNSAAAKKEQKRREADFRKLT
APIRKKLTQLEAKMDKLGEALAEAEQQLSDNSLYDAENKAKLTQVLALQAQSKSALEEIEMEWMAEQEVLEQMEQEFNSQ
>Mature_640_residues
MITFSDIQLLRGGSPLLDQASATIHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSSPQHWELAWVAQETPALERSA
IEYVIDGDREYRQLERQLAEAEAQEQGTRIAELHGKIETIGGYSIRARASELLDGLGFSQEQMHWNLTQFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVMWLERWLQSYPGTLMLISHDRDFLDPIVNRIVHIENQKLNEYTGNYSSFENQRAQ
KLILQQSMFEKQQKQMAHMQSYIDRFRYKASKARQAQSRIKALEKLEKVLPAQFDNPFSFEFREPAALPNPIMMMDDVSA
GYGDNLILDKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELKAQGGDLTYSQGVKIGYFAQHQLETLHPEETPLQHMMQ
IAPDKTEQELRNYLGSFGFHGDKALEKVAPFSGGEKARLVLALIVWQKPNLLLLDEPTNHLDLDMRQALTLALQTFEGAM
VIVSHDRYLIRATTDDLYLVHDRQVAPFDGDLNDYYKWLTEQQKAERREAAAEMPAKDSSNSAAAKKEQKRREADFRKLT
APIRKKLTQLEAKMDKLGEALAEAEQQLSDNSLYDAENKAKLTQVLALQAQSKSALEEIEMEWMAEQEVLEQMEQEFNSQ

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=535, Percent_Identity=37.3831775700935, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI10947137, Length=531, Percent_Identity=37.4764595103578, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI27881506, Length=531, Percent_Identity=37.4764595103578, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI10947135, Length=544, Percent_Identity=34.5588235294118, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI69354671, Length=544, Percent_Identity=34.5588235294118, Blast_Score=265, Evalue=1e-70,
Organism=Escherichia coli, GI1789751, Length=633, Percent_Identity=65.7187993680885, Blast_Score=870, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=33.4593572778828, Blast_Score=306, Evalue=3e-84,
Organism=Escherichia coli, GI1787182, Length=636, Percent_Identity=27.8301886792453, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI2367384, Length=526, Percent_Identity=30.9885931558935, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=30.0518134715026, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787758, Length=224, Percent_Identity=27.6785714285714, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787029, Length=216, Percent_Identity=26.8518518518519, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789891, Length=208, Percent_Identity=29.3269230769231, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788506, Length=207, Percent_Identity=26.5700483091787, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=536, Percent_Identity=39.1791044776119, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17559834, Length=533, Percent_Identity=35.8348968105066, Blast_Score=334, Evalue=9e-92,
Organism=Caenorhabditis elegans, GI17555318, Length=510, Percent_Identity=35.6862745098039, Blast_Score=322, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17541710, Length=255, Percent_Identity=27.0588235294118, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=542, Percent_Identity=35.6088560885609, Blast_Score=346, Evalue=6e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=527, Percent_Identity=34.1555977229602, Blast_Score=310, Evalue=4e-85,
Organism=Saccharomyces cerevisiae, GI6325030, Length=402, Percent_Identity=30.3482587064677, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324314, Length=399, Percent_Identity=27.3182957393484, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6323278, Length=397, Percent_Identity=26.9521410579345, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24666836, Length=535, Percent_Identity=37.9439252336449, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24642252, Length=543, Percent_Identity=35.7274401473296, Blast_Score=348, Evalue=9e-96,
Organism=Drosophila melanogaster, GI18859989, Length=543, Percent_Identity=35.7274401473296, Blast_Score=348, Evalue=9e-96,
Organism=Drosophila melanogaster, GI24641342, Length=535, Percent_Identity=34.9532710280374, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI116007184, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221500365, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72492; Mature: 72492

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFSDIQLLRGGSPLLDQASATIHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSS
CCCCHHHHHHCCCCCCHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PQHWELAWVAQETPALERSAIEYVIDGDREYRQLERQLAEAEAQEQGTRIAELHGKIETI
CCCEEEEEEECCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEC
GGYSIRARASELLDGLGFSQEQMHWNLTQFSGGWRMRLNLAQALLCRSDLLLLDEPTNHL
CCCCHHHHHHHHHHHCCCCHHHHEEEHEEECCCEEEHHHHHHHHHHHCCEEEEECCCCCC
DLDAVMWLERWLQSYPGTLMLISHDRDFLDPIVNRIVHIENQKLNEYTGNYSSFENQRAQ
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEECCCCHHHHHCCCHHHHHHHHHH
KLILQQSMFEKQQKQMAHMQSYIDRFRYKASKARQAQSRIKALEKLEKVLPAQFDNPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EFREPAALPNPIMMMDDVSAGYGDNLILDKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSG
CCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELKAQGGDLTYSQGVKIGYFAQHQLETLHPEETPLQHMMQIAPDKTEQELRNYLGSFGFH
HHHCCCCCEEHHCCCEEEEEHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCC
GDKALEKVAPFSGGEKARLVLALIVWQKPNLLLLDEPTNHLDLDMRQALTLALQTFEGAM
CHHHHHHHCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRYLIRATTDDLYLVHDRQVAPFDGDLNDYYKWLTEQQKAERREAAAEMPAKDSS
EEEECCCEEEEECCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSAAAKKEQKRREADFRKLTAPIRKKLTQLEAKMDKLGEALAEAEQQLSDNSLYDAENKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KLTQVLALQAQSKSALEEIEMEWMAEQEVLEQMEQEFNSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITFSDIQLLRGGSPLLDQASATIHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSS
CCCCHHHHHHCCCCCCHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PQHWELAWVAQETPALERSAIEYVIDGDREYRQLERQLAEAEAQEQGTRIAELHGKIETI
CCCEEEEEEECCCCCHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEC
GGYSIRARASELLDGLGFSQEQMHWNLTQFSGGWRMRLNLAQALLCRSDLLLLDEPTNHL
CCCCHHHHHHHHHHHCCCCHHHHEEEHEEECCCEEEHHHHHHHHHHHCCEEEEECCCCCC
DLDAVMWLERWLQSYPGTLMLISHDRDFLDPIVNRIVHIENQKLNEYTGNYSSFENQRAQ
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEECCCCHHHHHCCCHHHHHHHHHH
KLILQQSMFEKQQKQMAHMQSYIDRFRYKASKARQAQSRIKALEKLEKVLPAQFDNPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EFREPAALPNPIMMMDDVSAGYGDNLILDKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSG
CCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELKAQGGDLTYSQGVKIGYFAQHQLETLHPEETPLQHMMQIAPDKTEQELRNYLGSFGFH
HHHCCCCCEEHHCCCEEEEEHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCC
GDKALEKVAPFSGGEKARLVLALIVWQKPNLLLLDEPTNHLDLDMRQALTLALQTFEGAM
CHHHHHHHCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRYLIRATTDDLYLVHDRQVAPFDGDLNDYYKWLTEQQKAERREAAAEMPAKDSS
EEEECCCEEEEECCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSAAAKKEQKRREADFRKLTAPIRKKLTQLEAKMDKLGEALAEAEQQLSDNSLYDAENKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KLTQVLALQAQSKSALEEIEMEWMAEQEVLEQMEQEFNSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]