| Definition | Vibrio vulnificus CMCP6 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_004459 |
| Length | 3,281,866 |
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The map label for this gene is thiE [H]
Identifier: 27364402
GI number: 27364402
Start: 967687
End: 969021
Strand: Reverse
Name: thiE [H]
Synonym: VV1_0963
Alternate gene names: 27364402
Gene position: 969021-967687 (Counterclockwise)
Preceding gene: 27364403
Following gene: 27364401
Centisome position: 29.53
GC content: 46.74
Gene sequence:
>1335_bases ATGAGACTGCTGATTCCTTCTGCCATTATTGAGCTGACGGGAGAAATTCAGCAGTGTTTGCTCTTGGCAAAGCAGCAAGG TTTTGCCATTGACCATATAGAGTTGGGCGTCAGCCCAACTCGTACACTGCAACTGATTTCTTCAGCCAAAACAGTCGTAT TCGAGACGGATCTTATCCATAACGATAGTCGTCATCTCGGAGCGCATGACTTTGCGCTTCACTACCATCATTCGCTTGCT CTGACAGAGGTATCCAGTTATTTGGGCTCAGAGTGCAAGGCCAAGACGCTGTTGATCAATTTGCAAGGGGAGCAAGGTGA GGCGTTTGATGTTTGGCAACATCCTTTAGCCGATGAAACTCGCGCACTACGATTTTTATCACGACAAAACCACTCTCAAA ACGAGAGCGTAGAATCGATTTATCGACATTTAGCGTGGGTGGTCACGCTCAGTGCTCTTGATTTCCCAATCGAAGATTGC CTTACTTTGGCGCGTGCGATGTTGAATGTTTCACGTGAAACATGGGTGTCGGATTTTGCTTTGTTTCCTACACCAGTGTT GCATTTGGATGAGTTCGGCATCTTACCAAGCCACAATCTAGAAGGGCTAACAAAAGCGTTTCCGCGGGTTATCGCTCAAC AGTTAGGGCTCTATCCGGTGGTTGATGATGTCAGTTGGATTGAGAAGTTATTGCCTTTGGGGATTAAAACGGTCCAATTG CGGATTAAAGATCCAAACCAAGTCGATTTGGAGCAACAGATTGTGCGTGCGATCCAGCTAGGTCGTGACTATGGCGCGAA AGTCTATATCAACGACTACTGGCAGTTAGCTATTCAGTATCAAGCCTATGGCGTACATCTAGGGCAGGAAGATTTGCAGG TGGCTGATTTAGCCGCCCTGACGAATGCAGGCATTGCGTTAGGGTTATCTACGCATGGTTATTATGAGCTGTTACGCATT GTTCAACTCCAGCCAAGTTACATCGCATTGGGGCACATTTTCCCGACCACCACAAAACAAATGCCTTCATTACCGCAAGG GCTGGTGAGATTAAAACTCTATCAGCAATTGATTGATACCATACCTTATGATGAGTCCATCACCGGCGTTCCCACGGTAG CCATTGGTGGTATTGATCAAAGCAATGCGGCGACAGTATGGCAATGTGGTGTCTCTTCATTAGCGGTAGTGAGAGCGATT ACCTTGGCGAAAGATGTGAAAGCGGTAATAGAGTACTTCAAGCAAGTGATGGCACCTAACACAACACTGCTGCGTTTAGA CTCAGTATCCACACATAGTCTTGAGCCAACAAGTGAGGCCAATCATGTTGGTTGA
Upstream 100 bases:
>100_bases CATTGGAAGGAATGAAGCAAAAGTCCGCGGAATTCAAAGCGTCGGGTTCGGAGTTGTACCATCCTGCAGTGAGTCACGAA GAAGTGGCAGAGGGTTAAGT
Downstream 100 bases:
>100_bases TCGGCTCTTTACTCGTTATCAAAGACAAATTGCATTAACGGAATTTGGTGAGTCAGGGCAAGCCAACTTACTTCAAGCAC ATGTGCTGATCATCGGTTGC
Product: thiamine-phosphate pyrophosphorylase
Products: NA
Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]
Number of amino acids: Translated: 444; Mature: 444
Protein sequence:
>444_residues MRLLIPSAIIELTGEIQQCLLLAKQQGFAIDHIELGVSPTRTLQLISSAKTVVFETDLIHNDSRHLGAHDFALHYHHSLA LTEVSSYLGSECKAKTLLINLQGEQGEAFDVWQHPLADETRALRFLSRQNHSQNESVESIYRHLAWVVTLSALDFPIEDC LTLARAMLNVSRETWVSDFALFPTPVLHLDEFGILPSHNLEGLTKAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQL RIKDPNQVDLEQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYGVHLGQEDLQVADLAALTNAGIALGLSTHGYYELLRI VQLQPSYIALGHIFPTTTKQMPSLPQGLVRLKLYQQLIDTIPYDESITGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAI TLAKDVKAVIEYFKQVMAPNTTLLRLDSVSTHSLEPTSEANHVG
Sequences:
>Translated_444_residues MRLLIPSAIIELTGEIQQCLLLAKQQGFAIDHIELGVSPTRTLQLISSAKTVVFETDLIHNDSRHLGAHDFALHYHHSLA LTEVSSYLGSECKAKTLLINLQGEQGEAFDVWQHPLADETRALRFLSRQNHSQNESVESIYRHLAWVVTLSALDFPIEDC LTLARAMLNVSRETWVSDFALFPTPVLHLDEFGILPSHNLEGLTKAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQL RIKDPNQVDLEQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYGVHLGQEDLQVADLAALTNAGIALGLSTHGYYELLRI VQLQPSYIALGHIFPTTTKQMPSLPQGLVRLKLYQQLIDTIPYDESITGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAI TLAKDVKAVIEYFKQVMAPNTTLLRLDSVSTHSLEPTSEANHVG >Mature_444_residues MRLLIPSAIIELTGEIQQCLLLAKQQGFAIDHIELGVSPTRTLQLISSAKTVVFETDLIHNDSRHLGAHDFALHYHHSLA LTEVSSYLGSECKAKTLLINLQGEQGEAFDVWQHPLADETRALRFLSRQNHSQNESVESIYRHLAWVVTLSALDFPIEDC LTLARAMLNVSRETWVSDFALFPTPVLHLDEFGILPSHNLEGLTKAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQL RIKDPNQVDLEQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYGVHLGQEDLQVADLAALTNAGIALGLSTHGYYELLRI VQLQPSYIALGHIFPTTTKQMPSLPQGLVRLKLYQQLIDTIPYDESITGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAI TLAKDVKAVIEYFKQVMAPNTTLLRLDSVSTHSLEPTSEANHVG
Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]
COG id: COG0352
COG function: function code H; Thiamine monophosphate synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TMP-PPase family [H]
Homologues:
Organism=Escherichia coli, GI1790426, Length=190, Percent_Identity=55.7894736842105, Blast_Score=203, Evalue=2e-53, Organism=Saccharomyces cerevisiae, GI6325042, Length=216, Percent_Identity=26.8518518518519, Blast_Score=64, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR022998 - InterPro: IPR003733 [H]
Pfam domain/function: PF02581 TMP-TENI [H]
EC number: =2.5.1.3 [H]
Molecular weight: Translated: 49291; Mature: 49291
Theoretical pI: Translated: 5.79; Mature: 5.79
Prosite motif: PS00012 PHOSPHOPANTETHEINE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLLIPSAIIELTGEIQQCLLLAKQQGFAIDHIELGVSPTRTLQLISSAKTVVFETDLIH CCEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEHHEE NDSRHLGAHDFALHYHHSLALTEVSSYLGSECKAKTLLINLQGEQGEAFDVWQHPLADET CCCCCCCCHHEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHCCCCCHHH RALRFLSRQNHSQNESVESIYRHLAWVVTLSALDFPIEDCLTLARAMLNVSRETWVSDFA HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH LFPTPVLHLDEFGILPSHNLEGLTKAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQL HCCCCCEEHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCEEEEE RIKDPNQVDLEQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYGVHLGQEDLQVADLAAL EECCCCCCCHHHHHHHHHHHCCCCCCEEEEECEEEEEEEEEEEEEECCHHHHHHHHHHHH TNAGIALGLSTHGYYELLRIVQLQPSYIALGHIFPTTTKQMPSLPQGLVRLKLYQQLIDT HCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHH IPYDESITGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAITLAKDVKAVIEYFKQVMAPN CCCCCCCCCCCEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC TTLLRLDSVSTHSLEPTSEANHVG CEEEEEECCCCCCCCCCCCCCCCC >Mature Secondary Structure MRLLIPSAIIELTGEIQQCLLLAKQQGFAIDHIELGVSPTRTLQLISSAKTVVFETDLIH CCEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEHHEE NDSRHLGAHDFALHYHHSLALTEVSSYLGSECKAKTLLINLQGEQGEAFDVWQHPLADET CCCCCCCCHHEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHCCCCCHHH RALRFLSRQNHSQNESVESIYRHLAWVVTLSALDFPIEDCLTLARAMLNVSRETWVSDFA HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH LFPTPVLHLDEFGILPSHNLEGLTKAFPRVIAQQLGLYPVVDDVSWIEKLLPLGIKTVQL HCCCCCEEHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCEEEEE RIKDPNQVDLEQQIVRAIQLGRDYGAKVYINDYWQLAIQYQAYGVHLGQEDLQVADLAAL EECCCCCCCHHHHHHHHHHHCCCCCCEEEEECEEEEEEEEEEEEEECCHHHHHHHHHHHH TNAGIALGLSTHGYYELLRIVQLQPSYIALGHIFPTTTKQMPSLPQGLVRLKLYQQLIDT HCCCEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHH IPYDESITGVPTVAIGGIDQSNAATVWQCGVSSLAVVRAITLAKDVKAVIEYFKQVMAPN CCCCCCCCCCCEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC TTLLRLDSVSTHSLEPTSEANHVG CEEEEEECCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA