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The map label for this gene is 27364257

Identifier: 27364257

GI number: 27364257

Start: 816263

End: 817264

Strand: Reverse

Name: 27364257

Synonym: VV1_0808

Alternate gene names: NA

Gene position: 817264-816263 (Counterclockwise)

Preceding gene: 27364258

Following gene: 27364256

Centisome position: 24.9

GC content: 47.41

Gene sequence:

>1002_bases
ATGACAAACAAGACATTTATCATCGCTGAGGCCGGTGTAAACCATAATGGTGATATTCGTTTAGCCAAACAGTTGATTGA
TGCGGCGGCGGATGCGGGCGTCGATGCGGTGAAGTTCCAGACTTGGAAAACCGAATTACTGGTAACAGAAGACGCAAAAA
TGGCGGAATATCAAGTTGAAAACACTCAACGTGAAGAAACGCAATTTGAAATGCTGAAGCGTTTGGAATTGAGCTACGAT
GATTTTACAGAATTAAAGTCGTACTGTGATGATAAAGGTATTACCTTTATGTCAACGCCAGACGAAGAGCAAAGCGCCAC
ATTTTTAGATGGCTTACAAGCCGTATTCAAAATTGGCTCGGGAGAGCTCACCAACACACCATTTCTACGCCATATAGCGA
GCTTTGCCAAGCCAGTGATCTTGTCAACGGGGATGGGCTATTTGTCGGAAGTGGAGCATGCGGTGGTGACGTTGCGCGAC
GCGGGCTTATCACTCGACATGATCACGGTTTTACACGCGACAACCGATTATCCAACCGCGCCAGAAGACGTTAACTTGTT
GGCGATGAAGACGATCGAACAAGCGTTCCCGGGCATTATTGTCGGCTACTCTGATCATACGTTGGGTACTGAAATACCAG
TAGCAGCGGTGGCGCTAGGCGCGAAAGTGATTGAAAAACATTTCACGCTAGATAAAACCATGTCTGGGCCGGATCATAAA
GCTAGCCTCGAGCCACAAGAGCTCGCCGACATGGTCACTGCGATCCGCAATATTGAACAAGCTCTGGGTAATGGCTGGAA
GGTACCCACTAAAACCGAACAGGAAAACCGTAACATTGTGCGCAAGAGCTTAGTGGCTGGCAAGCCGATCATGGCGGGCA
GCATCATCTGTGCAGATATGTTAGAAATTAAACGTCCAGGTAATGGTATTTCTCCAACGCGTTGGGATGAAGTGGTTGGC
TCTATAGCGAAGAAAGATTACCAGATTGGAGAGCTGATCTAA

Upstream 100 bases:

>100_bases
TACCAGAGAAGAGGCACCAGTTGAATCAGTTGTGGATTGAGCAAAACCCGCAACGCCAAGCACCAAAGTTATTCCAGTTA
TACCGAGCTTAGAGGTACTT

Downstream 100 bases:

>100_bases
TGCGTAAAATCTGTGTAGTCACCGCCACGCGAGCGGAATATGGCTTACTGAAATGTTTGCTGGATGATATTCAAAATGAT
CCGCAACTTGAGTTACAAAT

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTNKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVENTQREETQFEMLKRLELSYD
DFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVFKIGSGELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRD
AGLSLDMITVLHATTDYPTAPEDVNLLAMKTIEQAFPGIIVGYSDHTLGTEIPVAAVALGAKVIEKHFTLDKTMSGPDHK
ASLEPQELADMVTAIRNIEQALGNGWKVPTKTEQENRNIVRKSLVAGKPIMAGSIICADMLEIKRPGNGISPTRWDEVVG
SIAKKDYQIGELI

Sequences:

>Translated_333_residues
MTNKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVENTQREETQFEMLKRLELSYD
DFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVFKIGSGELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRD
AGLSLDMITVLHATTDYPTAPEDVNLLAMKTIEQAFPGIIVGYSDHTLGTEIPVAAVALGAKVIEKHFTLDKTMSGPDHK
ASLEPQELADMVTAIRNIEQALGNGWKVPTKTEQENRNIVRKSLVAGKPIMAGSIICADMLEIKRPGNGISPTRWDEVVG
SIAKKDYQIGELI
>Mature_332_residues
TNKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVENTQREETQFEMLKRLELSYDD
FTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVFKIGSGELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRDA
GLSLDMITVLHATTDYPTAPEDVNLLAMKTIEQAFPGIIVGYSDHTLGTEIPVAAVALGAKVIEKHFTLDKTMSGPDHKA
SLEPQELADMVTAIRNIEQALGNGWKVPTKTEQENRNIVRKSLVAGKPIMAGSIICADMLEIKRPGNGISPTRWDEVVGS
IAKKDYQIGELI

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=301, Percent_Identity=38.8704318936877, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI21357081, Length=260, Percent_Identity=38.4615384615385, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 36505; Mature: 36374

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVE
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECEEEEEECCCHHHHHHHH
NTQREETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVFKIGS
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCC
GELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRDAGLSLDMITVLHATTDYPTA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCCCCC
PEDVNLLAMKTIEQAFPGIIVGYSDHTLGTEIPVAAVALGAKVIEKHFTLDKTMSGPDHK
CCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ASLEPQELADMVTAIRNIEQALGNGWKVPTKTEQENRNIVRKSLVAGKPIMAGSIICADM
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEIKRPGNGISPTRWDEVVGSIAKKDYQIGELI
HHHCCCCCCCCCCHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
TNKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVE
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECEEEEEECCCHHHHHHHH
NTQREETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVFKIGS
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCC
GELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRDAGLSLDMITVLHATTDYPTA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHCCCCCCC
PEDVNLLAMKTIEQAFPGIIVGYSDHTLGTEIPVAAVALGAKVIEKHFTLDKTMSGPDHK
CCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ASLEPQELADMVTAIRNIEQALGNGWKVPTKTEQENRNIVRKSLVAGKPIMAGSIICADM
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LEIKRPGNGISPTRWDEVVGSIAKKDYQIGELI
HHHCCCCCCCCCCHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]