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The map label for this gene is wzb [C]

Identifier: 27364232

GI number: 27364232

Start: 794512

End: 794952

Strand: Reverse

Name: wzb [C]

Synonym: VV1_0783

Alternate gene names: 27364232

Gene position: 794952-794512 (Counterclockwise)

Preceding gene: 27364233

Following gene: 27364231

Centisome position: 24.22

GC content: 45.35

Gene sequence:

>441_bases
ATGTTTAACAAAATCTTAGTCGTTTGTGTCGGTAACATTTGCCGCTCTCCAACTGGTGAGCGTGTGCTACAAAAACTACT
TCCGAATAAAACCGTTGCTTCTGCCGGTATTGCAGCAGAGAAAAGCCGTTTAATTGGTAAGCCAGCCGATGCAATGGCGA
TAGAAGTGGCAAAAGAGAATGGTGTTGATGTAGAAAACCATCAATCACAGCAACTTACCTCTGCGCTGTGTAGCCAATAT
GATCTGATCCTAGTCATGGAAAAAGGCCATATGGAAGCATTAACACAAATCGCCCCAGAAGCTCGCGGAAAAACTATGCT
ATTCGGCCAATGGATCGGGCAAAAAGATATCCCCGATCCGTACCGTCAAAGCAAAGAAGCCTTCGTGCACGCTTATCAGT
TGATTGACGAAGCCGCACAAGCCTGGGCAAAGAAATTGTAA

Upstream 100 bases:

>100_bases
AGGACCACAGGACCACAGGACCACAGGACCACAGGACCACAGGACCACAGGACCACAGGACCACAGGACCACAGGACCAA
TAATTCAATAGGCATTACTC

Downstream 100 bases:

>100_bases
TAAAAGGAAAAACTGACCTAGACGCTTGTATTCCTTTGCAATGCTTTTAGCCTTGACCACAGGACCACAGGACCACAGGA
CCACAGGACCACAGGACCAC

Product: low molecular weight protein-tyrosine-phosphatase wzb

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKENGVDVENHQSQQLTSALCSQY
DLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDPYRQSKEAFVHAYQLIDEAAQAWAKKL

Sequences:

>Translated_146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKENGVDVENHQSQQLTSALCSQY
DLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDPYRQSKEAFVHAYQLIDEAAQAWAKKL
>Mature_146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKENGVDVENHQSQQLTSALCSQY
DLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDPYRQSKEAFVHAYQLIDEAAQAWAKKL

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=149, Percent_Identity=29.5302013422819, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI6005988, Length=149, Percent_Identity=27.5167785234899, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788375, Length=146, Percent_Identity=54.1095890410959, Blast_Score=169, Evalue=7e-44,
Organism=Escherichia coli, GI87081812, Length=145, Percent_Identity=55.8620689655172, Blast_Score=163, Evalue=4e-42,
Organism=Drosophila melanogaster, GI78706766, Length=152, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI78706768, Length=152, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16064; Mature: 16064

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKEN
CCCCEEHEEHHHHHCCCCHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCCHHHEEECCCC
GVDVENHQSQQLTSALCSQYDLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDP
CCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
YRQSKEAFVHAYQLIDEAAQAWAKKL
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKEN
CCCCEEHEEHHHHHCCCCHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCCHHHEEECCCC
GVDVENHQSQQLTSALCSQYDLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDP
CCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
YRQSKEAFVHAYQLIDEAAQAWAKKL
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896702 [H]