Click here to switch to the map view.

The map label for this gene is ugd [H]

Identifier: 27364223

GI number: 27364223

Start: 775591

End: 776757

Strand: Reverse

Name: ugd [H]

Synonym: VV1_0774

Alternate gene names: 27364223

Gene position: 776757-775591 (Counterclockwise)

Preceding gene: 27364224

Following gene: 326423759

Centisome position: 23.67

GC content: 45.07

Gene sequence:

>1167_bases
ATGCGAATCACCGTCGTTGGGGCTGGCTACGTCGGCCTGGCTAATGCTGCACTTTTGGCACAGTACCATTCCATTATTCT
GCTCGATGTAGACTCTAAAAGAGTCGAACAAATCAATGCCAAAAGTAGCCCTATCGTAGATGTGGATATTGAGCGGTTCT
TATCGTCGGGGGCACTTCAGCTTACGGCCACCACATCACCACAGATTGCCTACCACGATGCGCAGCTGATTATTGTTGCT
ACTCCTACAAACTACGATCCCATTACCAATGGTTTTGATACGACTTCTGTTGAACAGGTGATTCAAGATGCGATTCAAAT
TAGCCCGAATGCCACGATTCTTATCCGTTCAACTGTGCCAGTCGGGTTTACAGAAAGAATGCGCACTCAAGTGGAAAGGC
GCAATATTCTCTTTGCTCCTGAGTTTCTGCGTGAGGGTAAGGCGCTGTACGACAATCTTTTTCCTTCTCGTATTGTCATC
GGAGAACAAAGTGAGCGTGGGCAGCAAATAGCGGAATTATTTGCCAACGCTGCCGAGAAAAGGGATGTGCCCATTTTGCT
GACTAACCCAACCGAAGCTGAAGCGATCAAGTTGTTTTCAAACACTTATTTGGCGATGCGCATCGCTTACTTCAACGAGT
TGGACTCCTATGCCGAAGCGCATGGTTTAGATGCTCGCCAGATCATTGAAGGGGTTGGCTTAGACCCTCGTATTGGCAAT
CACTACAACAACCCATCATTTGGTTATGGTGGATATTGCCTACCTAAAGATACCAAACAGCTGTTGGCGAATTACCAAGA
TGTACCCAACAACATTATTGGTGCCATTGTTGATGCTAACCGTACTCGCAAAGATTTTGTTGCTGAGTCGATTTTGAAGC
GCGAGCCCAAAGTCGTAGGTATTTATCGTTTAATCATGAAAGCAGGGTCGGATAATTTTCGCGCTTCCTCGATTCAAGGA
ATCATGAAACGCATCAAGGCCAAAGGCATTGAAGTTGTGGTTTATGAGCCTGTTTTGAAAGAGGCTGAATTTTTCCATTC
TCGTGTAATCAAAGATTTGAATGAGTTTAAGCAAACAGCGGACGTGATAGTCTCAAATCGCATGGTGAAAGAATTAACTG
ACGTTGCAGATAAAGTTTACACCCGTGATTTGTTTGGTAGTGACTGA

Upstream 100 bases:

>100_bases
ATATCGGCCTTTATCTTCCTTTCTTGTTATCTTAGCGTCTTAGAGGTGTAACATTCAGTTGTTGATATAGCGTGTAACGT
TGTCAATGACAGGAAATGTT

Downstream 100 bases:

>100_bases
AGCATTTGACTAGATAGCGAGCATGGTTGTCGGTGGCATGTCTGTATTTGTTGGTTGTGGTGAGTGCATTTTCAAACGCG
GCATCCGGCGCGTGTGGATG

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRITVVGAGYVGLANAALLAQYHSIILLDVDSKRVEQINAKSSPIVDVDIERFLSSGALQLTATTSPQIAYHDAQLIIVA
TPTNYDPITNGFDTTSVEQVIQDAIQISPNATILIRSTVPVGFTERMRTQVERRNILFAPEFLREGKALYDNLFPSRIVI
GEQSERGQQIAELFANAAEKRDVPILLTNPTEAEAIKLFSNTYLAMRIAYFNELDSYAEAHGLDARQIIEGVGLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQDVPNNIIGAIVDANRTRKDFVAESILKREPKVVGIYRLIMKAGSDNFRASSIQG
IMKRIKAKGIEVVVYEPVLKEAEFFHSRVIKDLNEFKQTADVIVSNRMVKELTDVADKVYTRDLFGSD

Sequences:

>Translated_388_residues
MRITVVGAGYVGLANAALLAQYHSIILLDVDSKRVEQINAKSSPIVDVDIERFLSSGALQLTATTSPQIAYHDAQLIIVA
TPTNYDPITNGFDTTSVEQVIQDAIQISPNATILIRSTVPVGFTERMRTQVERRNILFAPEFLREGKALYDNLFPSRIVI
GEQSERGQQIAELFANAAEKRDVPILLTNPTEAEAIKLFSNTYLAMRIAYFNELDSYAEAHGLDARQIIEGVGLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQDVPNNIIGAIVDANRTRKDFVAESILKREPKVVGIYRLIMKAGSDNFRASSIQG
IMKRIKAKGIEVVVYEPVLKEAEFFHSRVIKDLNEFKQTADVIVSNRMVKELTDVADKVYTRDLFGSD
>Mature_388_residues
MRITVVGAGYVGLANAALLAQYHSIILLDVDSKRVEQINAKSSPIVDVDIERFLSSGALQLTATTSPQIAYHDAQLIIVA
TPTNYDPITNGFDTTSVEQVIQDAIQISPNATILIRSTVPVGFTERMRTQVERRNILFAPEFLREGKALYDNLFPSRIVI
GEQSERGQQIAELFANAAEKRDVPILLTNPTEAEAIKLFSNTYLAMRIAYFNELDSYAEAHGLDARQIIEGVGLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQDVPNNIIGAIVDANRTRKDFVAESILKREPKVVGIYRLIMKAGSDNFRASSIQG
IMKRIKAKGIEVVVYEPVLKEAEFFHSRVIKDLNEFKQTADVIVSNRMVKELTDVADKVYTRDLFGSD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=365, Percent_Identity=27.9452054794521, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI296040443, Length=352, Percent_Identity=24.7159090909091, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI296040438, Length=266, Percent_Identity=29.3233082706767, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=68.0412371134021, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI48994968, Length=398, Percent_Identity=25.8793969849246, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560350, Length=393, Percent_Identity=28.2442748091603, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI17136908, Length=367, Percent_Identity=28.6103542234332, Blast_Score=125, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43191; Mature: 43191

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITVVGAGYVGLANAALLAQYHSIILLDVDSKRVEQINAKSSPIVDVDIERFLSSGALQ
CEEEEEECCHHHHHHHHHHHHHCEEEEEECCHHHHHHHCCCCCCEEEEEHHHHHCCCCEE
LTATTSPQIAYHDAQLIIVATPTNYDPITNGFDTTSVEQVIQDAIQISPNATILIRSTVP
EEECCCCCEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCC
VGFTERMRTQVERRNILFAPEFLREGKALYDNLFPSRIVIGEQSERGQQIAELFANAAEK
CCHHHHHHHHHHHCCEEECHHHHHCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
RDVPILLTNPTEAEAIKLFSNTYLAMRIAYFNELDSYAEAHGLDARQIIEGVGLDPRIGN
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQDVPNNIIGAIVDANRTRKDFVAESILKREPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHHHHHHHCCCCHHH
IYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVVYEPVLKEAEFFHSRVIKDLNEFKQTA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
DVIVSNRMVKELTDVADKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRITVVGAGYVGLANAALLAQYHSIILLDVDSKRVEQINAKSSPIVDVDIERFLSSGALQ
CEEEEEECCHHHHHHHHHHHHHCEEEEEECCHHHHHHHCCCCCCEEEEEHHHHHCCCCEE
LTATTSPQIAYHDAQLIIVATPTNYDPITNGFDTTSVEQVIQDAIQISPNATILIRSTVP
EEECCCCCEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCC
VGFTERMRTQVERRNILFAPEFLREGKALYDNLFPSRIVIGEQSERGQQIAELFANAAEK
CCHHHHHHHHHHHCCEEECHHHHHCCHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
RDVPILLTNPTEAEAIKLFSNTYLAMRIAYFNELDSYAEAHGLDARQIIEGVGLDPRIGN
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQDVPNNIIGAIVDANRTRKDFVAESILKREPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHCCCCHHHEEEECCCCCHHHHHHHHHHHCCCCHHH
IYRLIMKAGSDNFRASSIQGIMKRIKAKGIEVVVYEPVLKEAEFFHSRVIKDLNEFKQTA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
DVIVSNRMVKELTDVADKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]