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The map label for this gene is plsC [H]

Identifier: 27364135

GI number: 27364135

Start: 701102

End: 701827

Strand: Reverse

Name: plsC [H]

Synonym: VV1_0678

Alternate gene names: 27364135

Gene position: 701827-701102 (Counterclockwise)

Preceding gene: 27364136

Following gene: 27364130

Centisome position: 21.38

GC content: 46.97

Gene sequence:

>726_bases
ATGATTGCTCTAGTGCGTTTGTTAGCAACGGCGTTGTTTGCTGTTGTGATGTTCGTCTTTGGTTGTGGCTACTGTTTACT
TAGCCCTAGAAACCCTAAGCATGTGTTCACCTTTGGCCGTCTGTTTGCCAAAATGTCGCGTGTATTTGGCATTAAGCTGG
AACTGCGTCTTCCTGAAGATGCCTACCAACGTGGCCAACATATCTACATTGCCAACCACCAAAATAACTGGGACCTCTTT
ACCGTTTCTGCGGCAGTGACACCCAAAGTTGTCACGGTAGGCAAAAAGAGCCTAGCGTGGTTACCGCTGTTTGGACAGCT
TTACTGGCTGACGGGTAACATCTTGATTGACCGTGCGAATAAGACCAAAGCCAAAGGGACGATTGATCAGGTAGTGGCAA
GCATGAAAGCAAGTGAAGTTTCGGTATGGATGTTTCCTGAAGGCACACGCTCACGCGGTCGTGGTCTCATGCCTTTCAAA
ACGGGCGCTTTTCACGCTGCGATTGGCGCTGGCGTACCGATTATCCCGATCGTATGTAGTTCAACAGATCAACTGAAATT
GAATCGTTGGAATAATGGCCACGTGATTGTCGAAATGTTGGATCCCATTAGCACCGAAGGTTATGGCAAAGAGCATATTC
GCGAGCTTGCAGAAATCTGTCGCGCAAAGATGAAAGCCAAATTAGAAAGTTTGGATGAAGAAGTGAAGTTACGTAATCAG
CAATGA

Upstream 100 bases:

>100_bases
CTTTTTTATATTTTAGAAGCTGTTTTTGTCAGAGAAGTAGAGCGTGGCTTTCAATATCTTGGGAGTGCAATGCCTATCTG
AATGAATACCGGAGTTATAA

Downstream 100 bases:

>100_bases
TTCACTTAAAAATCGATGATTAAAATAAAAAGGATGTCATATGACATCCTTTTTTTGTTCCGGCTTAACTGAGTAAAATT
CGGGACTAAGCTTGCGGTTT

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIALVRLLATALFAVVMFVFGCGYCLLSPRNPKHVFTFGRLFAKMSRVFGIKLELRLPEDAYQRGQHIYIANHQNNWDLF
TVSAAVTPKVVTVGKKSLAWLPLFGQLYWLTGNILIDRANKTKAKGTIDQVVASMKASEVSVWMFPEGTRSRGRGLMPFK
TGAFHAAIGAGVPIIPIVCSSTDQLKLNRWNNGHVIVEMLDPISTEGYGKEHIRELAEICRAKMKAKLESLDEEVKLRNQ
Q

Sequences:

>Translated_241_residues
MIALVRLLATALFAVVMFVFGCGYCLLSPRNPKHVFTFGRLFAKMSRVFGIKLELRLPEDAYQRGQHIYIANHQNNWDLF
TVSAAVTPKVVTVGKKSLAWLPLFGQLYWLTGNILIDRANKTKAKGTIDQVVASMKASEVSVWMFPEGTRSRGRGLMPFK
TGAFHAAIGAGVPIIPIVCSSTDQLKLNRWNNGHVIVEMLDPISTEGYGKEHIRELAEICRAKMKAKLESLDEEVKLRNQ
Q
>Mature_241_residues
MIALVRLLATALFAVVMFVFGCGYCLLSPRNPKHVFTFGRLFAKMSRVFGIKLELRLPEDAYQRGQHIYIANHQNNWDLF
TVSAAVTPKVVTVGKKSLAWLPLFGQLYWLTGNILIDRANKTKAKGTIDQVVASMKASEVSVWMFPEGTRSRGRGLMPFK
TGAFHAAIGAGVPIIPIVCSSTDQLKLNRWNNGHVIVEMLDPISTEGYGKEHIRELAEICRAKMKAKLESLDEEVKLRNQ
Q

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=203, Percent_Identity=32.0197044334975, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI15100175, Length=203, Percent_Identity=32.0197044334975, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI6041665, Length=180, Percent_Identity=29.4444444444444, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1789395, Length=239, Percent_Identity=59.8326359832636, Blast_Score=307, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI17564032, Length=185, Percent_Identity=34.5945945945946, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17568319, Length=208, Percent_Identity=33.1730769230769, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320151, Length=231, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=7e-30,
Organism=Drosophila melanogaster, GI281364648, Length=228, Percent_Identity=28.9473684210526, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24582856, Length=228, Percent_Identity=28.9473684210526, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24582854, Length=228, Percent_Identity=28.9473684210526, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24641614, Length=188, Percent_Identity=37.2340425531915, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24641612, Length=188, Percent_Identity=37.2340425531915, Blast_Score=118, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26961; Mature: 26961

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALVRLLATALFAVVMFVFGCGYCLLSPRNPKHVFTFGRLFAKMSRVFGIKLELRLPED
CHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCHH
AYQRGQHIYIANHQNNWDLFTVSAAVTPKVVTVGKKSLAWLPLFGQLYWLTGNILIDRAN
HHHCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCEEEHHHHHEEEEEECEEEEECCC
KTKAKGTIDQVVASMKASEVSVWMFPEGTRSRGRGLMPFKTGAFHAAIGAGVPIIPIVCS
CCCCCCCHHHHHHHHHHCCEEEEECCCCCHHCCCCCCCCCCCCHHHHHCCCCCEEEEEEC
STDQLKLNRWNNGHVIVEMLDPISTEGYGKEHIRELAEICRAKMKAKLESLDEEVKLRNQ
CCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Q
C
>Mature Secondary Structure
MIALVRLLATALFAVVMFVFGCGYCLLSPRNPKHVFTFGRLFAKMSRVFGIKLELRLPED
CHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCHH
AYQRGQHIYIANHQNNWDLFTVSAAVTPKVVTVGKKSLAWLPLFGQLYWLTGNILIDRAN
HHHCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCEEEHHHHHEEEEEECEEEEECCC
KTKAKGTIDQVVASMKASEVSVWMFPEGTRSRGRGLMPFKTGAFHAAIGAGVPIIPIVCS
CCCCCCCHHHHHHHHHHCCEEEEECCCCCHHCCCCCCCCCCCCHHHHHCCCCCEEEEEEC
STDQLKLNRWNNGHVIVEMLDPISTEGYGKEHIRELAEICRAKMKAKLESLDEEVKLRNQ
CCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]