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The map label for this gene is ydiD [C]

Identifier: 27364106

GI number: 27364106

Start: 669419

End: 671224

Strand: Reverse

Name: ydiD [C]

Synonym: VV1_0649

Alternate gene names: 27364106

Gene position: 671224-669419 (Counterclockwise)

Preceding gene: 326423745

Following gene: 27364105

Centisome position: 20.45

GC content: 46.51

Gene sequence:

>1806_bases
ATGGCCAATTTAGATTTTCACATCGTAAAACGAATTCGTAAGCAGATTGCACAAGGTGCGGAGCGAGTTGCGCTCAAGCA
TAAAGTTGGTGCAGTTTGGCAAGGTATTAGCTGGAAGCAATTTGGTCAGCAAATTGATGAATTATCCCTAGCGTTGCTTG
CGCAGGGCATTGAAGTCCAAGATAAGATCGCTATCTTTTCTAATAACATGCCGCAGTGGACGGTGGCCGATTTTGCGGCC
CTACAATTACGTGCTGTCACGGTCCCGATTTATCCAACCAATACGGCAGCTCAAGCGGCTTATATTCTGCAAAATGCCGA
CGTTAAAGTTCTGTTTGTGGGTGAACAGCCACAATTTGACGCCGCAGTGAAAATCTTCGATGAGTGTGAGCAACTGAACC
TGATTGTCGCCATGTCAGACGATATTGATTTAGGCGAACATCACTTTGCGATCCATTGGAAAGCCTTCATTCAACAAGGT
CAACAAGAGGCCCGTGCTGAGCTCGAACGACGTTTAGAACAGGCAAATTTTGAGGATTTGCTGACGCTAATCTATACCTC
TGGCACCACGGGGCAGCCGAAAGGGGTGATGTTAGATTATGCCAACATTGCCGCTCAATTAGAGGGACATGATCGACGCT
TAAGCCTGACAGAAAACGACGTTTCGCTTTGTTTCTTGCCGTTATCACACGTTTTTGAGCGCGCTTGGACCTTTTACGTT
CTTTATAAAGGCGGTACGAACTGTTATTTGCAAGATACCATGCAAGTTCGTGACGCTCTGAGTGATATCAAGCCAACAGT
GATGTGCGCCGTGCCGCGCTTTTACGAGAAGATCTTCTCTGCCATCCATGAGAAAGTCTCTCGTGCGCCGCTGATGCGCA
AAATCATGTTTACCTGGGCGGTGAACATGGGCGCGAAGATGTCCGTGTGTCACCAAGAAGGTCGCCAGCCTTCATTGATG
CTGAAAAAAGCCCATGCGTTGGCGGATAAGCTGGTGTTGTCAAAACTGCGTGCCCTGCTGGGTGGCAACATCAACTTTAT
GCCATGTGGTGGTGCAAAACTGGATGAAACCATTGGTCGTTTCTTCCATGCGATTGGTATCAACGTGAAGCTGGGCTACG
GCATGACCGAAACCACAGCAACGATTTCATGCTGGGATGACAAGTGCTTTAACCCTGATTCTATCGGCATGTCGATGCCG
GGCGCACAAGTAAAGATTGGCGAAAACAACGAAATTTTGGTTCGTGGTCCGATGGTGATGCGTGGTTACTACAAGCTCCC
AGAAGAAACGGAGAAAACGTTTGATGAACACGGTTTCCTTAAAACGGGCGACGCGGGTCACATTGATGAGCACGGCAACC
TGTTCATTACCGATCGTATCAAAGAGCTGATGAAAACGTCTGGAGGAAAATACATTGCCCCGCAGATGATTGAAGGTGCG
ATTGGTAAAGATCATTTTATTGAGCAAATCGCGGTGATTGCTGATACACGCAAATTCGTTTCAGCGTTGATAGTGCCTTG
TTTTGACTCTTTGGAAGAGTACGCCAAAGAGCTCAATATTAAGTATCACGATCGCGTTGAACTGATTAAGCATCACCAAG
TTGTTGAAATGCTGGAGAAGCGCGTTAACGATCTGCAGAAAGAGCTGGCGAAATTTGAACAAGTGAAGAAGTTCAAGTTG
CTACCAAAAGCGTTTTCTATGGATGAAGGTGAGTTGACGCCAACGCAGAAATTGCGCCGTAAGGTGATCAACGACAAGTA
TCAAGACGAAATCGAAGAAATGTATTCAGAAAAGAAAGAAAAATAA

Upstream 100 bases:

>100_bases
ATTGAGCATAAGTTTGACCCTCATCAGTTGCGTTTTTTGTTCCCACCGCTACACTGTGCCCGCAAATAGAGCTTACATGT
GTAAGCCAAAGGTAAGAGAC

Downstream 100 bases:

>100_bases
GCTTTTCTGTCGAACATTGACGTCACATTGATCCTTGATGAACCTCACTGAGTGTGAAACACCAGTGAGGTTTTTCCGTC
TTTGACGCCTGTAGGCAAGC

Product: long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MANLDFHIVKRIRKQIAQGAERVALKHKVGAVWQGISWKQFGQQIDELSLALLAQGIEVQDKIAIFSNNMPQWTVADFAA
LQLRAVTVPIYPTNTAAQAAYILQNADVKVLFVGEQPQFDAAVKIFDECEQLNLIVAMSDDIDLGEHHFAIHWKAFIQQG
QQEARAELERRLEQANFEDLLTLIYTSGTTGQPKGVMLDYANIAAQLEGHDRRLSLTENDVSLCFLPLSHVFERAWTFYV
LYKGGTNCYLQDTMQVRDALSDIKPTVMCAVPRFYEKIFSAIHEKVSRAPLMRKIMFTWAVNMGAKMSVCHQEGRQPSLM
LKKAHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATISCWDDKCFNPDSIGMSMP
GAQVKIGENNEILVRGPMVMRGYYKLPEETEKTFDEHGFLKTGDAGHIDEHGNLFITDRIKELMKTSGGKYIAPQMIEGA
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRVELIKHHQVVEMLEKRVNDLQKELAKFEQVKKFKL
LPKAFSMDEGELTPTQKLRRKVINDKYQDEIEEMYSEKKEK

Sequences:

>Translated_601_residues
MANLDFHIVKRIRKQIAQGAERVALKHKVGAVWQGISWKQFGQQIDELSLALLAQGIEVQDKIAIFSNNMPQWTVADFAA
LQLRAVTVPIYPTNTAAQAAYILQNADVKVLFVGEQPQFDAAVKIFDECEQLNLIVAMSDDIDLGEHHFAIHWKAFIQQG
QQEARAELERRLEQANFEDLLTLIYTSGTTGQPKGVMLDYANIAAQLEGHDRRLSLTENDVSLCFLPLSHVFERAWTFYV
LYKGGTNCYLQDTMQVRDALSDIKPTVMCAVPRFYEKIFSAIHEKVSRAPLMRKIMFTWAVNMGAKMSVCHQEGRQPSLM
LKKAHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATISCWDDKCFNPDSIGMSMP
GAQVKIGENNEILVRGPMVMRGYYKLPEETEKTFDEHGFLKTGDAGHIDEHGNLFITDRIKELMKTSGGKYIAPQMIEGA
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRVELIKHHQVVEMLEKRVNDLQKELAKFEQVKKFKL
LPKAFSMDEGELTPTQKLRRKVINDKYQDEIEEMYSEKKEK
>Mature_600_residues
ANLDFHIVKRIRKQIAQGAERVALKHKVGAVWQGISWKQFGQQIDELSLALLAQGIEVQDKIAIFSNNMPQWTVADFAAL
QLRAVTVPIYPTNTAAQAAYILQNADVKVLFVGEQPQFDAAVKIFDECEQLNLIVAMSDDIDLGEHHFAIHWKAFIQQGQ
QEARAELERRLEQANFEDLLTLIYTSGTTGQPKGVMLDYANIAAQLEGHDRRLSLTENDVSLCFLPLSHVFERAWTFYVL
YKGGTNCYLQDTMQVRDALSDIKPTVMCAVPRFYEKIFSAIHEKVSRAPLMRKIMFTWAVNMGAKMSVCHQEGRQPSLML
KKAHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGRFFHAIGINVKLGYGMTETTATISCWDDKCFNPDSIGMSMPG
AQVKIGENNEILVRGPMVMRGYYKLPEETEKTFDEHGFLKTGDAGHIDEHGNLFITDRIKELMKTSGGKYIAPQMIEGAI
GKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRVELIKHHQVVEMLEKRVNDLQKELAKFEQVKKFKLL
PKAFSMDEGELTPTQKLRRKVINDKYQDEIEEMYSEKKEK

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI27477105, Length=635, Percent_Identity=27.244094488189, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI42794760, Length=594, Percent_Identity=29.4612794612795, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI42794758, Length=594, Percent_Identity=29.4612794612795, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI42794756, Length=594, Percent_Identity=29.4612794612795, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI40807491, Length=606, Percent_Identity=28.5478547854785, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI57165412, Length=594, Percent_Identity=28.7878787878788, Blast_Score=219, Evalue=7e-57,
Organism=Homo sapiens, GI57165410, Length=594, Percent_Identity=28.7878787878788, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI83745141, Length=613, Percent_Identity=26.1011419249592, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI42794754, Length=586, Percent_Identity=28.3276450511945, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI42794752, Length=586, Percent_Identity=28.3276450511945, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI12669909, Length=605, Percent_Identity=23.801652892562, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI4758332, Length=605, Percent_Identity=23.801652892562, Blast_Score=161, Evalue=2e-39,
Organism=Escherichia coli, GI145693145, Length=463, Percent_Identity=25.9179265658747, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788107, Length=485, Percent_Identity=23.7113402061856, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786810, Length=461, Percent_Identity=22.9934924078091, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17556552, Length=614, Percent_Identity=28.3387622149837, Blast_Score=238, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17541856, Length=597, Percent_Identity=30.6532663316583, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17510401, Length=598, Percent_Identity=28.0936454849498, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI193204819, Length=633, Percent_Identity=29.0679304897314, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17553312, Length=622, Percent_Identity=25.7234726688103, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17564090, Length=545, Percent_Identity=26.7889908256881, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25147511, Length=631, Percent_Identity=24.7226624405705, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17558820, Length=537, Percent_Identity=24.5810055865922, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17531443, Length=326, Percent_Identity=26.9938650306748, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17559526, Length=342, Percent_Identity=28.0701754385965, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32563687, Length=477, Percent_Identity=23.6897274633124, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133901848, Length=215, Percent_Identity=28.8372093023256, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=346, Percent_Identity=24.8554913294798, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324893, Length=447, Percent_Identity=28.8590604026846, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6320852, Length=584, Percent_Identity=25.6849315068493, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322182, Length=465, Percent_Identity=28.8172043010753, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323903, Length=602, Percent_Identity=25.9136212624585, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281366413, Length=591, Percent_Identity=30.9644670050761, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24666501, Length=591, Percent_Identity=30.9644670050761, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24666497, Length=591, Percent_Identity=30.9644670050761, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI17933690, Length=625, Percent_Identity=25.92, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI19921316, Length=620, Percent_Identity=27.741935483871, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI62471679, Length=592, Percent_Identity=27.7027027027027, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI62471683, Length=592, Percent_Identity=27.7027027027027, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI62471685, Length=592, Percent_Identity=27.7027027027027, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24586636, Length=592, Percent_Identity=27.7027027027027, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI62471689, Length=592, Percent_Identity=27.7027027027027, Blast_Score=185, Evalue=9e-47,
Organism=Drosophila melanogaster, GI62471681, Length=615, Percent_Identity=27.479674796748, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI62471687, Length=615, Percent_Identity=27.479674796748, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24586634, Length=615, Percent_Identity=27.479674796748, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI22026970, Length=615, Percent_Identity=27.479674796748, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21355181, Length=498, Percent_Identity=25.3012048192771, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24653035, Length=190, Percent_Identity=33.1578947368421, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24648260, Length=125, Percent_Identity=33.6, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281365686, Length=204, Percent_Identity=29.9019607843137, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356947, Length=220, Percent_Identity=26.3636363636364, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076582, Length=190, Percent_Identity=32.6315789473684, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358303, Length=207, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 68130; Mature: 67998

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLDFHIVKRIRKQIAQGAERVALKHKVGAVWQGISWKQFGQQIDELSLALLAQGIEVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
DKIAIFSNNMPQWTVADFAALQLRAVTVPIYPTNTAAQAAYILQNADVKVLFVGEQPQFD
HEEEEEECCCCCCHHHHHHHEEEEEEEEEEECCCHHHHHHHHEECCCEEEEEECCCCCHH
AAVKIFDECEQLNLIVAMSDDIDLGEHHFAIHWKAFIQQGQQEARAELERRLEQANFEDL
HHHHHHHHHHHCEEEEEECCCCCCCCCEEEEHHHHHHHHCHHHHHHHHHHHHHHCCHHHH
LTLIYTSGTTGQPKGVMLDYANIAAQLEGHDRRLSLTENDVSLCFLPLSHVFERAWTFYV
HHHHEECCCCCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHHEEEEE
LYKGGTNCYLQDTMQVRDALSDIKPTVMCAVPRFYEKIFSAIHEKVSRAPLMRKIMFTWA
EEECCCCEEEHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNMGAKMSVCHQEGRQPSLMLKKAHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGR
HCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FFHAIGINVKLGYGMTETTATISCWDDKCFNPDSIGMSMPGAQVKIGENNEILVRGPMVM
HHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHC
RGYYKLPEETEKTFDEHGFLKTGDAGHIDEHGNLFITDRIKELMKTSGGKYIAPQMIEGA
CCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHCC
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRVELIKHHQVVEMLEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RVNDLQKELAKFEQVKKFKLLPKAFSMDEGELTPTQKLRRKVINDKYQDEIEEMYSEKKE
HHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
ANLDFHIVKRIRKQIAQGAERVALKHKVGAVWQGISWKQFGQQIDELSLALLAQGIEVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHH
DKIAIFSNNMPQWTVADFAALQLRAVTVPIYPTNTAAQAAYILQNADVKVLFVGEQPQFD
HEEEEEECCCCCCHHHHHHHEEEEEEEEEEECCCHHHHHHHHEECCCEEEEEECCCCCHH
AAVKIFDECEQLNLIVAMSDDIDLGEHHFAIHWKAFIQQGQQEARAELERRLEQANFEDL
HHHHHHHHHHHCEEEEEECCCCCCCCCEEEEHHHHHHHHCHHHHHHHHHHHHHHCCHHHH
LTLIYTSGTTGQPKGVMLDYANIAAQLEGHDRRLSLTENDVSLCFLPLSHVFERAWTFYV
HHHHEECCCCCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHHEEEEE
LYKGGTNCYLQDTMQVRDALSDIKPTVMCAVPRFYEKIFSAIHEKVSRAPLMRKIMFTWA
EEECCCCEEEHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNMGAKMSVCHQEGRQPSLMLKKAHALADKLVLSKLRALLGGNINFMPCGGAKLDETIGR
HCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FFHAIGINVKLGYGMTETTATISCWDDKCFNPDSIGMSMPGAQVKIGENNEILVRGPMVM
HHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHC
RGYYKLPEETEKTFDEHGFLKTGDAGHIDEHGNLFITDRIKELMKTSGGKYIAPQMIEGA
CCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHCC
IGKDHFIEQIAVIADTRKFVSALIVPCFDSLEEYAKELNIKYHDRVELIKHHQVVEMLEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RVNDLQKELAKFEQVKKFKLLPKAFSMDEGELTPTQKLRRKVINDKYQDEIEEMYSEKKE
HHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]