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The map label for this gene is betA [C]

Identifier: 23502890

GI number: 23502890

Start: 1965405

End: 1967039

Strand: Reverse

Name: betA [C]

Synonym: BR2042

Alternate gene names: 23502890

Gene position: 1967039-1965405 (Counterclockwise)

Preceding gene: 23502891

Following gene: 23502887

Centisome position: 93.32

GC content: 58.47

Gene sequence:

>1635_bases
ATGCATTACGATTATATCATCGTTGGAGGCGGGCCTGCCGGTTGCGTTCTCGCCAATCGCCTGAGCGAAGATGCATCGAT
AAAAGTGTTGCTGCTGGAAGCCGGTGGAAGCGACTGGAATCCGCTGTTCCACATGCCTGCCGGTTTTGCCAAGATGACCA
AGGGGGTGGCAAGCTGGGGCTGGCAAACCGTGCCGCAAAAGCACATGAAGAACCGTGTGCTGCGCTATACGCAGGCGAAA
GTCATCGGTGGCGGCTCCTCGATCAATGCGCAGATTTATACGCGCGGCAATGCCGCCGATTACGATCTGTGGACCGATGA
AGAGGGCTGTACCGGCTGGGATTATCGCAGCGTGCTGCCCTATTTCAAACGCGCCGAGGACAATCAGCGTTTCAACGACG
ATTATCATGCCTATGGCGGGCCGCTTGGCGTTTCCATGCCATCCGCGCCGCTGCCGATCTGCGATGCCTATATCCGCGCC
GGGCAGGAGCTGGGCATCCCGTATAATCCGGATTTCAATGGCCGCGAGCAGCCAGGCATCGGCTTTTATCAGCTTACCCA
GCGCAACCGCCGCCGTTCTTCTGCTTCGCTTGCCTATCTTGCGCCGATCAGGGATCGCCGGAACCTGACAATCCGTATGA
ATGCGCAGGTAGCCACTATCGTGCTGGAAAAGACACGCGCCATCGGCGTTGCACTGATGAGCGGCGAGGTCTTGCGGGCG
AGCCGTGAGGTGATTGTTTCGTCCGGCGCCATCGGCTCGCCGAAACTTTTGCTGCAATCGGGCATCGGCCCGGCCGATCA
TTTGAAAAAGGTTGGCATTGCAGTGAAACACGATCTACCGGGCGTCGGTGAAAACATGCAGGATCACCTTGACCTGTTTG
TCATTGCCGAATGCACCGGCGACCACACCTATGACGGCGTGGCAAAGCTGCATCGCACGCTTGCCGCCGGCCTGCAATAT
GTGCTGCTACGCTCCGGCCCGGTGGCATCGAGCCTGTTTGAAACCGGCGGCTTCTGGTATGCCGACCCGGATGCCCGCTC
GCCGGATATCCAGTTTCATCTGGGGTTGGGGTCGGGCATTGAGGCAGGTGTCGAGAAGCTCAAGAATGCTGGCGTGACAC
TCAACTCCGCCTATTTGCATCCGCGCTCGCGCGGGACGGTGCGGCTTGCTTCCAATGATCCGGCATTGCCTCCCCTGATA
GACCCCAATTACTGGAGCGATCCGCATGATCGAAAAATGTCGCTTGAAGGATTGAAGATCGCGCGCGAAATCATGCAGCA
GGATGCATTGAAGCCCTATGTCATGGCCGAACGCCTGCCGGGGCCGAAGGTGGTTACAGACGATGATCTGTTCGATTATG
CCTGCGCCAATGCCAAGACCGACCATCATCCGGTCGGCACCTGCAAGATGGGCGGCGATGCCATGGCTGTGGTTGATCTC
GACCTCAAGGTGCGCGGTCTTGAGGGCCTGCGCGTCTGCGACAGCTCGGTCATGCCGCGTGTTCCTTCCTGCAACACCAA
TGCGCCGACCATCATGATCGGCGAAAAGGGAGCAGACATTATTCGCGGCCTCGATCCGCTGCCGCCAGCCGTATTTTCCT
GGGAGAGAAATGAAAAATATCGCCCGGCAGGATGA

Upstream 100 bases:

>100_bases
ATCGTGGCCGGGCTTGCCGGTGGCGATTTCATCTTTGCGACCGGCTCGGCAATCCATGCCGATGGCGGCCTGTCGATTGC
AAAATTATAAGGGTAGCGCG

Downstream 100 bases:

>100_bases
ACAAGCAGGATGAACAACTTCGCCGGAACGTATTGCCGCTTCGGCGAAGTTGTTGTGTCTGTGATCGGTTTACTTGCAGC
TTTCCGACGCTTTTACAATT

Product: L-sorbose dehydrogenase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MHYDYIIVGGGPAGCVLANRLSEDASIKVLLLEAGGSDWNPLFHMPAGFAKMTKGVASWGWQTVPQKHMKNRVLRYTQAK
VIGGGSSINAQIYTRGNAADYDLWTDEEGCTGWDYRSVLPYFKRAEDNQRFNDDYHAYGGPLGVSMPSAPLPICDAYIRA
GQELGIPYNPDFNGREQPGIGFYQLTQRNRRRSSASLAYLAPIRDRRNLTIRMNAQVATIVLEKTRAIGVALMSGEVLRA
SREVIVSSGAIGSPKLLLQSGIGPADHLKKVGIAVKHDLPGVGENMQDHLDLFVIAECTGDHTYDGVAKLHRTLAAGLQY
VLLRSGPVASSLFETGGFWYADPDARSPDIQFHLGLGSGIEAGVEKLKNAGVTLNSAYLHPRSRGTVRLASNDPALPPLI
DPNYWSDPHDRKMSLEGLKIAREIMQQDALKPYVMAERLPGPKVVTDDDLFDYACANAKTDHHPVGTCKMGGDAMAVVDL
DLKVRGLEGLRVCDSSVMPRVPSCNTNAPTIMIGEKGADIIRGLDPLPPAVFSWERNEKYRPAG

Sequences:

>Translated_544_residues
MHYDYIIVGGGPAGCVLANRLSEDASIKVLLLEAGGSDWNPLFHMPAGFAKMTKGVASWGWQTVPQKHMKNRVLRYTQAK
VIGGGSSINAQIYTRGNAADYDLWTDEEGCTGWDYRSVLPYFKRAEDNQRFNDDYHAYGGPLGVSMPSAPLPICDAYIRA
GQELGIPYNPDFNGREQPGIGFYQLTQRNRRRSSASLAYLAPIRDRRNLTIRMNAQVATIVLEKTRAIGVALMSGEVLRA
SREVIVSSGAIGSPKLLLQSGIGPADHLKKVGIAVKHDLPGVGENMQDHLDLFVIAECTGDHTYDGVAKLHRTLAAGLQY
VLLRSGPVASSLFETGGFWYADPDARSPDIQFHLGLGSGIEAGVEKLKNAGVTLNSAYLHPRSRGTVRLASNDPALPPLI
DPNYWSDPHDRKMSLEGLKIAREIMQQDALKPYVMAERLPGPKVVTDDDLFDYACANAKTDHHPVGTCKMGGDAMAVVDL
DLKVRGLEGLRVCDSSVMPRVPSCNTNAPTIMIGEKGADIIRGLDPLPPAVFSWERNEKYRPAG
>Mature_544_residues
MHYDYIIVGGGPAGCVLANRLSEDASIKVLLLEAGGSDWNPLFHMPAGFAKMTKGVASWGWQTVPQKHMKNRVLRYTQAK
VIGGGSSINAQIYTRGNAADYDLWTDEEGCTGWDYRSVLPYFKRAEDNQRFNDDYHAYGGPLGVSMPSAPLPICDAYIRA
GQELGIPYNPDFNGREQPGIGFYQLTQRNRRRSSASLAYLAPIRDRRNLTIRMNAQVATIVLEKTRAIGVALMSGEVLRA
SREVIVSSGAIGSPKLLLQSGIGPADHLKKVGIAVKHDLPGVGENMQDHLDLFVIAECTGDHTYDGVAKLHRTLAAGLQY
VLLRSGPVASSLFETGGFWYADPDARSPDIQFHLGLGSGIEAGVEKLKNAGVTLNSAYLHPRSRGTVRLASNDPALPPLI
DPNYWSDPHDRKMSLEGLKIAREIMQQDALKPYVMAERLPGPKVVTDDDLFDYACANAKTDHHPVGTCKMGGDAMAVVDL
DLKVRGLEGLRVCDSSVMPRVPSCNTNAPTIMIGEKGADIIRGLDPLPPAVFSWERNEKYRPAG

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=536, Percent_Identity=40.8582089552239, Blast_Score=373, Evalue=1e-103,
Organism=Escherichia coli, GI1786503, Length=538, Percent_Identity=40.1486988847584, Blast_Score=368, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17532301, Length=551, Percent_Identity=37.7495462794918, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24642055, Length=576, Percent_Identity=38.3680555555556, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24642042, Length=563, Percent_Identity=40.1420959147425, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24642048, Length=568, Percent_Identity=36.9718309859155, Blast_Score=313, Evalue=3e-85,
Organism=Drosophila melanogaster, GI45551458, Length=570, Percent_Identity=36.6666666666667, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=36.6666666666667, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24642059, Length=567, Percent_Identity=37.5661375661376, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI17137792, Length=558, Percent_Identity=37.0967741935484, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24642037, Length=572, Percent_Identity=36.3636363636364, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24642039, Length=564, Percent_Identity=35.8156028368794, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24650267, Length=569, Percent_Identity=34.4463971880492, Blast_Score=275, Evalue=7e-74,
Organism=Drosophila melanogaster, GI18859995, Length=565, Percent_Identity=34.5132743362832, Blast_Score=268, Evalue=7e-72,
Organism=Drosophila melanogaster, GI24642035, Length=572, Percent_Identity=34.965034965035, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24642051, Length=564, Percent_Identity=33.6879432624113, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI18859993, Length=565, Percent_Identity=34.5132743362832, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24645930, Length=571, Percent_Identity=27.4956217162872, Blast_Score=158, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24642057, Length=575, Percent_Identity=30.7826086956522, Blast_Score=158, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 59294; Mature: 59294

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYDYIIVGGGPAGCVLANRLSEDASIKVLLLEAGGSDWNPLFHMPAGFAKMTKGVASWG
CCEEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHCC
WQTVPQKHMKNRVLRYTQAKVIGGGSSINAQIYTRGNAADYDLWTDEEGCTGWDYRSVLP
CCCCCHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
YFKRAEDNQRFNDDYHAYGGPLGVSMPSAPLPICDAYIRAGQELGIPYNPDFNGREQPGI
HHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GFYQLTQRNRRRSSASLAYLAPIRDRRNLTIRMNAQVATIVLEKTRAIGVALMSGEVLRA
CHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCEEEEEEEEHHHEEEEEEECCHHHHH
SREVIVSSGAIGSPKLLLQSGIGPADHLKKVGIAVKHDLPGVGENMQDHLDLFVIAECTG
CCCEEEECCCCCCCHHHHHCCCCHHHHHHHHCEEEECCCCCCCCCHHHCCEEEEEEECCC
DHTYDGVAKLHRTLAAGLQYVLLRSGPVASSLFETGGFWYADPDARSPDIQFHLGLGSGI
CCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCEEEECCCCCCCCEEEEEECCCCH
EAGVEKLKNAGVTLNSAYLHPRSRGTVRLASNDPALPPLIDPNYWSDPHDRKMSLEGLKI
HHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AREIMQQDALKPYVMAERLPGPKVVTDDDLFDYACANAKTDHHPVGTCKMGGDAMAVVDL
HHHHHHHHCCCCHHHHHCCCCCCEECCCCHHHHHHCCCCCCCCCCEEEEECCCEEEEEEE
DLKVRGLEGLRVCDSSVMPRVPSCNTNAPTIMIGEKGADIIRGLDPLPPAVFSWERNEKY
EEEEECCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCHHEECCCCCCC
RPAG
CCCC
>Mature Secondary Structure
MHYDYIIVGGGPAGCVLANRLSEDASIKVLLLEAGGSDWNPLFHMPAGFAKMTKGVASWG
CCEEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHCC
WQTVPQKHMKNRVLRYTQAKVIGGGSSINAQIYTRGNAADYDLWTDEEGCTGWDYRSVLP
CCCCCHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
YFKRAEDNQRFNDDYHAYGGPLGVSMPSAPLPICDAYIRAGQELGIPYNPDFNGREQPGI
HHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GFYQLTQRNRRRSSASLAYLAPIRDRRNLTIRMNAQVATIVLEKTRAIGVALMSGEVLRA
CHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCEEEEEEEEHHHEEEEEEECCHHHHH
SREVIVSSGAIGSPKLLLQSGIGPADHLKKVGIAVKHDLPGVGENMQDHLDLFVIAECTG
CCCEEEECCCCCCCHHHHHCCCCHHHHHHHHCEEEECCCCCCCCCHHHCCEEEEEEECCC
DHTYDGVAKLHRTLAAGLQYVLLRSGPVASSLFETGGFWYADPDARSPDIQFHLGLGSGI
CCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHCCCEEEECCCCCCCCEEEEEECCCCH
EAGVEKLKNAGVTLNSAYLHPRSRGTVRLASNDPALPPLIDPNYWSDPHDRKMSLEGLKI
HHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AREIMQQDALKPYVMAERLPGPKVVTDDDLFDYACANAKTDHHPVGTCKMGGDAMAVVDL
HHHHHHHHCCCCHHHHHCCCCCCEECCCCHHHHHHCCCCCCCCCCEEEEECCCEEEEEEE
DLKVRGLEGLRVCDSSVMPRVPSCNTNAPTIMIGEKGADIIRGLDPLPPAVFSWERNEKY
EEEEECCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCHHEECCCCCCC
RPAG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]