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The map label for this gene is etfA [H]

Identifier: 23502818

GI number: 23502818

Start: 1899776

End: 1900705

Strand: Reverse

Name: etfA [H]

Synonym: BR1970

Alternate gene names: 23502818

Gene position: 1900705-1899776 (Counterclockwise)

Preceding gene: 23502819

Following gene: 23502817

Centisome position: 90.18

GC content: 60.65

Gene sequence:

>930_bases
ATGGCTATTCTTCTTATTGCCGAACATGACAATGCAACCCTTTCCGACCAGACCGCCAAGGCGCTGACTGCGGCTGCCCA
GATCGGCGGCGACGTGGACGTTCTGGTTGCAGGCAAGGGCGCTAAGGCTGCCGCCGATGCAGCCGCCAAGCTCAAAGGCG
TGCGCAAGGTTCTGCTTGCTGAAAGCGATGCGCTGGAAAACCGTCTGGCCGAGCCGACGGCAGAGCTCATCGTTGCTCTG
GCAGGCAATTACGATACGATCATCGCACCGGCGACGACGTCGGCCAAGAACATCCTGCCGCGCGTGGCAGCCCTTCTCGA
TGTGATGCAACTGTCCGAAATCATGGAAGTGGTTTCCGCCGACACGTTCAAGCGCCCGATCTATGCGGGCAATGCGATCC
AGACCGTGCAGTCCACCGACGCCAAGAAGGTTATCACGGTTCGCACCGCTTCCTTCCAGGCGACCGGCGAAGGCGGTTCG
GCTTCGGTTGAAAGCGTCAATGCACCAGCCGATCCGGCGCTGTCGAGCTTTGTCGAAAACGCGCTTTCGGGCGGCGACCG
CCCGGAACTGACCTCGGCCAAGATCATCATCTCCGGTGGCCGTGCGCTGGGTTCTGCTGAAAAGTTCCAGGAAGTGATCC
TGCCGGTTGCCGATAAGCTGGGTGCCGCGGTTGGTGCAAGCCGTGCGGCGGTCGATGCGGGCTACGCGCCAAACGACTGG
CAGGTTGGCCAGACGGGCAAGGTGGTCGCGCCAGACCTTTATATCGCCGTTGGCATTTCCGGCGCGATCCAGCATCTGGC
TGGCATGAAGGACAGCCGCATCATCGTCGCTATCAACAAGGATGAAGAAGCGCCGATCTTCCAGGTCGCCGATTACGGCC
TCGTCGGTGATCTCTTCACCGTTCTGCCTGAGCTTGAAAAGGCTCTCTGA

Upstream 100 bases:

>100_bases
CTCACGTACGAAAGGTACGCTCCGCTCCGGTTCTCGCACCCCACCATTTTCGCCAGGGCCTGACAGGTTTCCGGCACCGG
ATGAATTAAGGACAGAAACA

Downstream 100 bases:

>100_bases
TCAAGTTTGCGAGGCGGCGGGTTAAACCGCCGCTTCCAGCGTTTACGGCCCGTTCCTATTCAGCGGGACAATATATATCG
CTTCGGATATGACGAAAATG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAILLIAEHDNATLSDQTAKALTAAAQIGGDVDVLVAGKGAKAAADAAAKLKGVRKVLLAESDALENRLAEPTAELIVAL
AGNYDTIIAPATTSAKNILPRVAALLDVMQLSEIMEVVSADTFKRPIYAGNAIQTVQSTDAKKVITVRTASFQATGEGGS
ASVESVNAPADPALSSFVENALSGGDRPELTSAKIIISGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSRIIVAINKDEEAPIFQVADYGLVGDLFTVLPELEKAL

Sequences:

>Translated_309_residues
MAILLIAEHDNATLSDQTAKALTAAAQIGGDVDVLVAGKGAKAAADAAAKLKGVRKVLLAESDALENRLAEPTAELIVAL
AGNYDTIIAPATTSAKNILPRVAALLDVMQLSEIMEVVSADTFKRPIYAGNAIQTVQSTDAKKVITVRTASFQATGEGGS
ASVESVNAPADPALSSFVENALSGGDRPELTSAKIIISGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSRIIVAINKDEEAPIFQVADYGLVGDLFTVLPELEKAL
>Mature_308_residues
AILLIAEHDNATLSDQTAKALTAAAQIGGDVDVLVAGKGAKAAADAAAKLKGVRKVLLAESDALENRLAEPTAELIVALA
GNYDTIIAPATTSAKNILPRVAALLDVMQLSEIMEVVSADTFKRPIYAGNAIQTVQSTDAKKVITVRTASFQATGEGGSA
SVESVNAPADPALSSFVENALSGGDRPELTSAKIIISGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDWQ
VGQTGKVVAPDLYIAVGISGAIQHLAGMKDSRIIVAINKDEEAPIFQVADYGLVGDLFTVLPELEKAL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=309, Percent_Identity=54.0453074433657, Blast_Score=308, Evalue=4e-84,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=54.9090909090909, Blast_Score=279, Evalue=2e-75,
Organism=Escherichia coli, GI1786226, Length=197, Percent_Identity=35.5329949238579, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787990, Length=118, Percent_Identity=40.6779661016949, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082157, Length=119, Percent_Identity=40.3361344537815, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=53.6977491961415, Blast_Score=311, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6325261, Length=313, Percent_Identity=41.5335463258786, Blast_Score=243, Evalue=3e-65,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=57.0512820512821, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=57.0512820512821, Blast_Score=317, Evalue=9e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31682; Mature: 31551

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILLIAEHDNATLSDQTAKALTAAAQIGGDVDVLVAGKGAKAAADAAAKLKGVRKVLLA
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
ESDALENRLAEPTAELIVALAGNYDTIIAPATTSAKNILPRVAALLDVMQLSEIMEVVSA
CCHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DTFKRPIYAGNAIQTVQSTDAKKVITVRTASFQATGEGGSASVESVNAPADPALSSFVEN
HHHCCCCCCCCHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
ALSGGDRPELTSAKIIISGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSRIIVAINKDEEAPIFQVADYGLVGDLFT
CCCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
VLPELEKAL
HHHHHHHCC
>Mature Secondary Structure 
AILLIAEHDNATLSDQTAKALTAAAQIGGDVDVLVAGKGAKAAADAAAKLKGVRKVLLA
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
ESDALENRLAEPTAELIVALAGNYDTIIAPATTSAKNILPRVAALLDVMQLSEIMEVVSA
CCHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DTFKRPIYAGNAIQTVQSTDAKKVITVRTASFQATGEGGSASVESVNAPADPALSSFVEN
HHHCCCCCCCCHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
ALSGGDRPELTSAKIIISGGRALGSAEKFQEVILPVADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPDLYIAVGISGAIQHLAGMKDSRIIVAINKDEEAPIFQVADYGLVGDLFT
CCCCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
VLPELEKAL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]