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The map label for this gene is clpB [H]

Identifier: 23502717

GI number: 23502717

Start: 1800024

End: 1802648

Strand: Reverse

Name: clpB [H]

Synonym: BR1864

Alternate gene names: 23502717

Gene position: 1802648-1800024 (Counterclockwise)

Preceding gene: 23502718

Following gene: 23502715

Centisome position: 85.52

GC content: 58.78

Gene sequence:

>2625_bases
ATGAATATCGAAAAATATACAGAACGGGTCCGCGGCTTCATCCAGTCTGCCCAGACCTTCGCGCTTTCCTCCGGCAATCA
GCAATTCACTCCAGAACATATCCTGAAGGTTCTCATCGACGACGATGAGGGGTTGGCGGCGTCGCTGGTCGAGCGGGCTG
GCGGACGGGTTGGCGATGTGCGCATGGGCCTGCAAAGCGCGCTTGAAAAACTGCCGAAAGTTTCGGGTGGCAATGACCAG
CTCTATCTTTCGCAGCCTCTTGCCAAGGTGTTCTCGCTTGCCGAGGAACTGGCCAGCAAGGCGGGTGACAGCTTCGTCAC
CGTCGAGCGCCTCCTGACGGCGCTGGCGATGGAAAAATCCGCCAAAACCTCCGAGATACTTTCTGCTGCGGGCGTCACCC
CGACGGCATTGAACAGGGTTATCAACGATATGCGCAAAGGCCGCACCGCCGATTCCGCCTCAGCCGAAAGCAATTATGAT
GCTTTGAAGAAATATGCGCGCGATCTGACGGAAGACGCACGCGCGGGCAAGCTTGATCCGGTCATCGGCCGCGATGAGGA
AATCCGCCGCACGATCCAGGTTCTGTCACGCCGCACCAAGAACAATCCGGTGCTGATCGGTGAGCCGGGCGTGGGCAAGA
CCGCAATCGCGGAAGGTCTGGCGCTGCGCATCGTCAATGGCGACGTGCCCGAATCGCTGAAGGACAAGCAATTGATGGCG
CTCGACATGGGCGCGCTGATTGCGGGCGCCAAATATCGCGGCGAATTCGAGGAACGCCTGAAGGCCGTTCTCTCGGAAGT
GCAGACGGCTGCCGGGCAGATCATCCTCTTCATCGACGAAATGCACACATTGGTCGGCGCGGGCAAGACGGATGGCGCAA
TGGATGCGTCGAACCTTTTGAAGCCTGCTCTGGCGCGCGGTGAATTGCATTGCGTCGGCGCCACCACGCTTGAGGAATAT
CGCAAATATGTGGAGAAGGACGCCGCCCTTGCGCGCCGTTTCCAGCCCGTTTTTGTCGATGAGCCAACAGTGGAGGACAC
AATCTCCATTCTGCGTGGCCTGAAGGAGAAATACGAGCAGCACCATAAGGTGCGCGTGTCGGACTCCGCGCTGGTGGCTG
CGGCAACGCTCTCAAACCGCTATATCACCGACCGTTTCCTGCCGGACAAGGCCATCGACCTTGTGGATGAGGCTGCATCG
CGCCTGCGTATGCACGTCGATTCCAAGCCGGAAGAACTGGACGAGATCGATCGCCGCATCATGCAGCTCAAGATCGAGCG
CGAAGCACTGAAGGTGGAAACGGACGCCGCTTCCAAGGACCGCTTGCAGCGCATTGAAAAGGAACTGAGCGATCTTGAGG
AAGAATCAGCCGAACTGACCGCCAAGTGGCAGGCGGAAAAGCAGAAGCTTGGGCTTGCTGCCGATCTCAAGCGTCAGCTT
GAAGAGGCACGCAATGCACTTGCCATTGCGCAGCGCAATGGTGAGTTTCAGAAAGCGGGCGAGCTTGCCTATGGCACGAT
CCCGCAACTGGAAAAGCAACTTGCTGATGCGGAAAGTCAGGAAAACAAGGGTTCCCTCCTGGAAGAAACCGTGACGCCGG
ACCATGTGGCGCAGGTCATTTCGCGCTGGACCGGCATTCCGGTTGACCGGATGCTGGAAGGTGAGCGCGAAAAGCTGTTG
CGCATGGAAGACGAGATCGGCAAGCGCGTCGTCGGCCAGGGCGAGGCGGTGCAGGCCATATCCAAGGCGGTGCGCCGTGC
CCGTGCCGGTCTGCAGGACCCGAACCGGCCCATCGGCTCGTTCATCTTCCTCGGCCCCACTGGCGTCGGCAAGACGGAAC
TCACCAAGGCGCTCGCCTCGTTCCTGTTCCAGGATGATACCGCAATGGTGCGTATCGATATGTCGGAATTCATGGAAAAG
CATTCCGTGAGCCGCCTTATCGGTGCTCCTCCCGGCTATGTCGGCTATGAAGAGGGTGGTGTGCTGACCGAAGCTGTCCG
GCGCAGGCCCTATCAGGTGATCCTGTTCGACGAGATTGAAAAGGCGCACCCGGATGTCTTCAATGTTCTGTTGCAGGTGC
TGGACGACGGACGCCTGACGGACGGCCAGGGCCGCACGGTTGATTTCCGCAATACGGTCATCATCATGACGTCAAACCTC
GGCGCGGAATATCTCGTCAATCTGGGCGAAAACGATGATGTCGAGACTGTTCGCGATGATGTGATGGGCGTGGTCCGTGC
TTCGTTCCGGCCGGAATTCCTCAACCGTGTTGATGAAATCATCCTGTTCCACCGGCTGCGCCGCGAAGACATGGGTGCAA
TTGTCGATATCCAGATGCAGCGTCTCCAATATCTGCTTTCCGATCGCAAGATCACCTTGCAGCTTGAGGACGACGCCCGC
GAATGGCTCGCCAACAAGGGGTATGACCCGGCCTATGGCGCGCGCCCGCTGAAGCGCGTAATCCAGAAGGAAGTGCAGGA
TCCGCTGGCCGAACGTATCCTGCTTGGTGATATTCTCGACGGTTCCCTCGTCAAGATCACTGCCGGTTCGGATCGGCTCA
ATTTCCGTCCGATCAGCGGTGCGTTCAGCGCGGCGGAGCCGGAAAGAGAAGACGAGAAAGCCTGA

Upstream 100 bases:

>100_bases
ATTCCCATATGCACTTTTGAGAAGAGCCCGCCCTTGTGGGGGGTCGTCACCCAACATCTCTCGGTGCCGCGGGACGGACC
GAGAGGCAAACGGAGACATT

Downstream 100 bases:

>100_bases
CAAAACAAACCTGCCCGGCTTCCTGTCGGGGGGCATCGGCGCTGCGACCTAGCCGGTCGCGGCGCTTTTTCTTTTGGAAG
CTGCATCTTTCCCGCCATCT

Product: ATP-dependent Clp protease, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MNIEKYTERVRGFIQSAQTFALSSGNQQFTPEHILKVLIDDDEGLAASLVERAGGRVGDVRMGLQSALEKLPKVSGGNDQ
LYLSQPLAKVFSLAEELASKAGDSFVTVERLLTALAMEKSAKTSEILSAAGVTPTALNRVINDMRKGRTADSASAESNYD
ALKKYARDLTEDARAGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
LDMGALIAGAKYRGEFEERLKAVLSEVQTAAGQIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLEEY
RKYVEKDAALARRFQPVFVDEPTVEDTISILRGLKEKYEQHHKVRVSDSALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMHVDSKPEELDEIDRRIMQLKIEREALKVETDAASKDRLQRIEKELSDLEEESAELTAKWQAEKQKLGLAADLKRQL
EEARNALAIAQRNGEFQKAGELAYGTIPQLEKQLADAESQENKGSLLEETVTPDHVAQVISRWTGIPVDRMLEGEREKLL
RMEDEIGKRVVGQGEAVQAISKAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALASFLFQDDTAMVRIDMSEFMEK
HSVSRLIGAPPGYVGYEEGGVLTEAVRRRPYQVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GAEYLVNLGENDDVETVRDDVMGVVRASFRPEFLNRVDEIILFHRLRREDMGAIVDIQMQRLQYLLSDRKITLQLEDDAR
EWLANKGYDPAYGARPLKRVIQKEVQDPLAERILLGDILDGSLVKITAGSDRLNFRPISGAFSAAEPEREDEKA

Sequences:

>Translated_874_residues
MNIEKYTERVRGFIQSAQTFALSSGNQQFTPEHILKVLIDDDEGLAASLVERAGGRVGDVRMGLQSALEKLPKVSGGNDQ
LYLSQPLAKVFSLAEELASKAGDSFVTVERLLTALAMEKSAKTSEILSAAGVTPTALNRVINDMRKGRTADSASAESNYD
ALKKYARDLTEDARAGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
LDMGALIAGAKYRGEFEERLKAVLSEVQTAAGQIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLEEY
RKYVEKDAALARRFQPVFVDEPTVEDTISILRGLKEKYEQHHKVRVSDSALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMHVDSKPEELDEIDRRIMQLKIEREALKVETDAASKDRLQRIEKELSDLEEESAELTAKWQAEKQKLGLAADLKRQL
EEARNALAIAQRNGEFQKAGELAYGTIPQLEKQLADAESQENKGSLLEETVTPDHVAQVISRWTGIPVDRMLEGEREKLL
RMEDEIGKRVVGQGEAVQAISKAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALASFLFQDDTAMVRIDMSEFMEK
HSVSRLIGAPPGYVGYEEGGVLTEAVRRRPYQVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GAEYLVNLGENDDVETVRDDVMGVVRASFRPEFLNRVDEIILFHRLRREDMGAIVDIQMQRLQYLLSDRKITLQLEDDAR
EWLANKGYDPAYGARPLKRVIQKEVQDPLAERILLGDILDGSLVKITAGSDRLNFRPISGAFSAAEPEREDEKA
>Mature_874_residues
MNIEKYTERVRGFIQSAQTFALSSGNQQFTPEHILKVLIDDDEGLAASLVERAGGRVGDVRMGLQSALEKLPKVSGGNDQ
LYLSQPLAKVFSLAEELASKAGDSFVTVERLLTALAMEKSAKTSEILSAAGVTPTALNRVINDMRKGRTADSASAESNYD
ALKKYARDLTEDARAGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
LDMGALIAGAKYRGEFEERLKAVLSEVQTAAGQIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLEEY
RKYVEKDAALARRFQPVFVDEPTVEDTISILRGLKEKYEQHHKVRVSDSALVAAATLSNRYITDRFLPDKAIDLVDEAAS
RLRMHVDSKPEELDEIDRRIMQLKIEREALKVETDAASKDRLQRIEKELSDLEEESAELTAKWQAEKQKLGLAADLKRQL
EEARNALAIAQRNGEFQKAGELAYGTIPQLEKQLADAESQENKGSLLEETVTPDHVAQVISRWTGIPVDRMLEGEREKLL
RMEDEIGKRVVGQGEAVQAISKAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALASFLFQDDTAMVRIDMSEFMEK
HSVSRLIGAPPGYVGYEEGGVLTEAVRRRPYQVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GAEYLVNLGENDDVETVRDDVMGVVRASFRPEFLNRVDEIILFHRLRREDMGAIVDIQMQRLQYLLSDRKITLQLEDDAR
EWLANKGYDPAYGARPLKRVIQKEVQDPLAERILLGDILDGSLVKITAGSDRLNFRPISGAFSAAEPEREDEKA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=336, Percent_Identity=34.5238095238095, Blast_Score=198, Evalue=2e-50,
Organism=Escherichia coli, GI1788943, Length=854, Percent_Identity=59.2505854800937, Blast_Score=1028, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=323, Percent_Identity=45.2012383900929, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6320464, Length=703, Percent_Identity=56.1877667140825, Blast_Score=801, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=860, Percent_Identity=43.8372093023256, Blast_Score=687, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96908; Mature: 96908

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEKYTERVRGFIQSAQTFALSSGNQQFTPEHILKVLIDDDEGLAASLVERAGGRVGDV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHH
RMGLQSALEKLPKVSGGNDQLYLSQPLAKVFSLAEELASKAGDSFVTVERLLTALAMEKS
HHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
AKTSEILSAAGVTPTALNRVINDMRKGRTADSASAESNYDALKKYARDLTEDARAGKLDP
CHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
VIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCCCCCHHHH
LDMGALIAGAKYRGEFEERLKAVLSEVQTAAGQIILFIDEMHTLVGAGKTDGAMDASNLL
HHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLEEYRKYVEKDAALARRFQPVFVDEPTVEDTISILRGLKEKYEQ
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHKVRVSDSALVAAATLSNRYITDRFLPDKAIDLVDEAASRLRMHVDSKPEELDEIDRRI
HCCEEECCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MQLKIEREALKVETDAASKDRLQRIEKELSDLEEESAELTAKWQAEKQKLGLAADLKRQL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EEARNALAIAQRNGEFQKAGELAYGTIPQLEKQLADAESQENKGSLLEETVTPDHVAQVI
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHH
SRWTGIPVDRMLEGEREKLLRMEDEIGKRVVGQGEAVQAISKAVRRARAGLQDPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELTKALASFLFQDDTAMVRIDMSEFMEKHSVSRLIGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
VLTEAVRRRPYQVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
HHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GAEYLVNLGENDDVETVRDDVMGVVRASFRPEFLNRVDEIILFHRLRREDMGAIVDIQMQ
CHHHHEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RLQYLLSDRKITLQLEDDAREWLANKGYDPAYGARPLKRVIQKEVQDPLAERILLGDILD
HHHHHHCCCEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GSLVKITAGSDRLNFRPISGAFSAAEPEREDEKA
CCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIEKYTERVRGFIQSAQTFALSSGNQQFTPEHILKVLIDDDEGLAASLVERAGGRVGDV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHH
RMGLQSALEKLPKVSGGNDQLYLSQPLAKVFSLAEELASKAGDSFVTVERLLTALAMEKS
HHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
AKTSEILSAAGVTPTALNRVINDMRKGRTADSASAESNYDALKKYARDLTEDARAGKLDP
CHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
VIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCCCCCCCHHHH
LDMGALIAGAKYRGEFEERLKAVLSEVQTAAGQIILFIDEMHTLVGAGKTDGAMDASNLL
HHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHH
KPALARGELHCVGATTLEEYRKYVEKDAALARRFQPVFVDEPTVEDTISILRGLKEKYEQ
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHKVRVSDSALVAAATLSNRYITDRFLPDKAIDLVDEAASRLRMHVDSKPEELDEIDRRI
HCCEEECCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MQLKIEREALKVETDAASKDRLQRIEKELSDLEEESAELTAKWQAEKQKLGLAADLKRQL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EEARNALAIAQRNGEFQKAGELAYGTIPQLEKQLADAESQENKGSLLEETVTPDHVAQVI
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHH
SRWTGIPVDRMLEGEREKLLRMEDEIGKRVVGQGEAVQAISKAVRRARAGLQDPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELTKALASFLFQDDTAMVRIDMSEFMEKHSVSRLIGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
VLTEAVRRRPYQVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
HHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GAEYLVNLGENDDVETVRDDVMGVVRASFRPEFLNRVDEIILFHRLRREDMGAIVDIQMQ
CHHHHEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RLQYLLSDRKITLQLEDDAREWLANKGYDPAYGARPLKRVIQKEVQDPLAERILLGDILD
HHHHHHCCCEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GSLVKITAGSDRLNFRPISGAFSAAEPEREDEKA
CCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]