Click here to switch to the map view.

The map label for this gene is mtgA [H]

Identifier: 23502632

GI number: 23502632

Start: 1704662

End: 1705396

Strand: Reverse

Name: mtgA [H]

Synonym: BR1776

Alternate gene names: 23502632

Gene position: 1705396-1704662 (Counterclockwise)

Preceding gene: 23502634

Following gene: 23502631

Centisome position: 80.91

GC content: 56.87

Gene sequence:

>735_bases
GTGAAAGTGACAAAAATCATCATCAAGAGCAAGGATGGTCGCAATTATCTGGCGGACCCCGTGTGGGGAAGCCGGATTGC
CGTCGCGCTCAGGATATTGGTGGTTCTGGCGATCCTGCCGGTTTTCCTGCTCCTCGTCTATTCACTGCCCTTCGTGCGGC
CGGTTTCCACGTTGATGGTGAAGGATTATGCGCTATTGCAGGGCGTGAACCGGCAATGGGTGGATATTGAGAATATCGCG
CCGGTTCTGGTCAATTCGGTGATGATGGCGGAGGATGGCCAATTTTGCAGCCACGGTGGGGTGGACTGGCATCAGCTAGG
CCTCGTTCTGGACGATGCGGGAGACGGGGGCCCGAGCCGTGGGGCATCCACCATCACCATGCAGATGGTGAAGAACCTGT
TTTTGTGGAATGGGCGCTCCTATCTGCGCAAAGGGCTGGAATTTCCGCTGGCGTTGATAGCCGATGCCGTTCTTTCCAAA
AAGCGTATCATGGAGATTTATCTCAATATCGCCGAGTGGGGGCCGGGCATCTATGGCATTGAGGCCGCAGCCCGGCATTA
TTTCAAACGGTCGGCGGCAAAACTGACGGCAAGACAGGCCGCACTGCTGGCGGTCACGCTGCCCAATCCGGCTTTGCGTA
ACCCGGCCAAACCGACGCGCAACATGCAGCGCATTGCCCGCATCGTGGCAGGACGTGCGATGCGATCCGGACCTTATGTG
ACTTGTGTGAAATAA

Upstream 100 bases:

>100_bases
CGCTCCCCGCATTTCGCCTTGTTTCGTGCGGTGGGTTATGGAATCGGGTTCAATATTATTAAGGAATGGTTTATGTCGCT
TGGAGGGCGCGCGGCAGGCG

Downstream 100 bases:

>100_bases
ACACGCCAGAAATGCGAAAGCGGAAAAAAAGATAAGACTCCCGCTGGTCAAATGCCGCGAGAGCGTGTATAGGCACCTGA
CTTTCCGGAATTTTGTCGGG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKVTKIIIKSKDGRNYLADPVWGSRIAVALRILVVLAILPVFLLLVYSLPFVRPVSTLMVKDYALLQGVNRQWVDIENIA
PVLVNSVMMAEDGQFCSHGGVDWHQLGLVLDDAGDGGPSRGASTITMQMVKNLFLWNGRSYLRKGLEFPLALIADAVLSK
KRIMEIYLNIAEWGPGIYGIEAAARHYFKRSAAKLTARQAALLAVTLPNPALRNPAKPTRNMQRIARIVAGRAMRSGPYV
TCVK

Sequences:

>Translated_244_residues
MKVTKIIIKSKDGRNYLADPVWGSRIAVALRILVVLAILPVFLLLVYSLPFVRPVSTLMVKDYALLQGVNRQWVDIENIA
PVLVNSVMMAEDGQFCSHGGVDWHQLGLVLDDAGDGGPSRGASTITMQMVKNLFLWNGRSYLRKGLEFPLALIADAVLSK
KRIMEIYLNIAEWGPGIYGIEAAARHYFKRSAAKLTARQAALLAVTLPNPALRNPAKPTRNMQRIARIVAGRAMRSGPYV
TCVK
>Mature_244_residues
MKVTKIIIKSKDGRNYLADPVWGSRIAVALRILVVLAILPVFLLLVYSLPFVRPVSTLMVKDYALLQGVNRQWVDIENIA
PVLVNSVMMAEDGQFCSHGGVDWHQLGLVLDDAGDGGPSRGASTITMQMVKNLFLWNGRSYLRKGLEFPLALIADAVLSK
KRIMEIYLNIAEWGPGIYGIEAAARHYFKRSAAKLTARQAALLAVTLPNPALRNPAKPTRNMQRIARIVAGRAMRSGPYV
TCVK

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=198, Percent_Identity=43.4343434343434, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786343, Length=153, Percent_Identity=37.9084967320261, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082258, Length=146, Percent_Identity=35.6164383561644, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788867, Length=200, Percent_Identity=29.5, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26925; Mature: 26925

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTKIIIKSKDGRNYLADPVWGSRIAVALRILVVLAILPVFLLLVYSLPFVRPVSTLMV
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KDYALLQGVNRQWVDIENIAPVLVNSVMMAEDGQFCSHGGVDWHQLGLVLDDAGDGGPSR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCEEEECCCCCCCCC
GASTITMQMVKNLFLWNGRSYLRKGLEFPLALIADAVLSKKRIMEIYLNIAEWGPGIYGI
CHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EAAARHYFKRSAAKLTARQAALLAVTLPNPALRNPAKPTRNMQRIARIVAGRAMRSGPYV
HHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEE
TCVK
EEEC
>Mature Secondary Structure
MKVTKIIIKSKDGRNYLADPVWGSRIAVALRILVVLAILPVFLLLVYSLPFVRPVSTLMV
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KDYALLQGVNRQWVDIENIAPVLVNSVMMAEDGQFCSHGGVDWHQLGLVLDDAGDGGPSR
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCEEEECCCCCCCCC
GASTITMQMVKNLFLWNGRSYLRKGLEFPLALIADAVLSKKRIMEIYLNIAEWGPGIYGI
CHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EAAARHYFKRSAAKLTARQAALLAVTLPNPALRNPAKPTRNMQRIARIVAGRAMRSGPYV
HHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEE
TCVK
EEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]