Click here to switch to the map view.

The map label for this gene is mraW [H]

Identifier: 23502310

GI number: 23502310

Start: 1398276

End: 1399316

Strand: Reverse

Name: mraW [H]

Synonym: BR1439

Alternate gene names: 23502310

Gene position: 1399316-1398276 (Counterclockwise)

Preceding gene: 23502314

Following gene: 23502309

Centisome position: 66.39

GC content: 61.48

Gene sequence:

>1041_bases
ATGGCAAGCCTCGGCGGAGACAATTCTCAAGCCGAAGGGGCTGAAGTCCGTCACGTTCCGGTGCTGATCGCCGAAGTGAT
CGACGCCCTGAAGCCAGCGCCCGGCGCGGTGATCGTTGATGGTACCTTCGGGGCCGGGGGCTATACCCGTCGCATTCTGG
AAACGGGTGCGGATGTGATCGCGATTGACCGCGACCCTACCGCAATCGAGGCCGGGCGGGCGATGGAAAAGGAATTTCCG
GGCAGGCTCAATCTGGTCGAAAGCCGGTTTTCTGCCCTTGATGAAGCGGTTGCCCGGATGAGTGGAGCAGGAAAGAAAGT
GGACGGCGTTGTGCTCGATATCGGCGTGTCGTCGATGCAGATCGACGAAGCCGAGCGTGGCTTTTCCTTTCAGAAGGATG
GCCCGCTCGACATGCGCATGTCGAGCAGGGGGCCAAGTGCTGCCGATGCCGTCAACCGCCTCAAGACGGGCGATCTGGCG
CGCATCTTCAACTTTCTGGGCGAGGAACGTCATGCAGGGCGGATTGCGCGCATGATCGAAAAACGCCGCGCGGCGAAACC
GTTCACCCGAACGCTTGACCTGGCCAATGCTATCGAAACGCTGGTGGGCCGCAACCCCAAGGACCGCATTCATCCGGCGA
CGCGCGTGTTTCAGGCGCTGCGCGTCTATGTGAATGACGAGCTGGGCGAGCTGGCGCGCGCATTGCTTGCCGCAGAACGC
ATCCTCAAGCCGGGCGGGCGTCTGGTTGTTGTTACATTCCATTCGCTTGAAGACCGCATGGTGAAGCGCTTCTTTGCGGA
TCGCGCTGGTGGCAGCGCCGGTTCGCGGCATATGCCGGAAACGCATATGCGCCTGCCAAGCTTCACGCCTGCGGTAAAGG
GGGCTGTCGGCCCGACGCCTGAGGAAGAAGAACGAAATCCCCGCGCGCGCTCGGCAAAGCTGCGCGCAGGCATCAGGACG
GAAAATCCGCCTCTCGAAGACGATTTATCGCTATTCGGCTTGCCCAAGCTGCCTGAAACGAACGAACTGGCCCGGAGTTG
A

Upstream 100 bases:

>100_bases
GGCGGGGACCGGCTTTGGGGTAAAATATGCATAGAAACAAACGATTAAAGCGCCCCGCGCATCGGATAACGGGCTTTGCA
CCCGGGAAAGGATCAGAATG

Downstream 100 bases:

>100_bases
ACGAGTGCTGCGTACTTTCGACATCATCATGATAGCGGCGATGCTGGTGGCGGCGACCGTCACCTATACGATCAAGTATG
AGGCTGAAAAGCAGATCGCC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MASLGGDNSQAEGAEVRHVPVLIAEVIDALKPAPGAVIVDGTFGAGGYTRRILETGADVIAIDRDPTAIEAGRAMEKEFP
GRLNLVESRFSALDEAVARMSGAGKKVDGVVLDIGVSSMQIDEAERGFSFQKDGPLDMRMSSRGPSAADAVNRLKTGDLA
RIFNFLGEERHAGRIARMIEKRRAAKPFTRTLDLANAIETLVGRNPKDRIHPATRVFQALRVYVNDELGELARALLAAER
ILKPGGRLVVVTFHSLEDRMVKRFFADRAGGSAGSRHMPETHMRLPSFTPAVKGAVGPTPEEEERNPRARSAKLRAGIRT
ENPPLEDDLSLFGLPKLPETNELARS

Sequences:

>Translated_346_residues
MASLGGDNSQAEGAEVRHVPVLIAEVIDALKPAPGAVIVDGTFGAGGYTRRILETGADVIAIDRDPTAIEAGRAMEKEFP
GRLNLVESRFSALDEAVARMSGAGKKVDGVVLDIGVSSMQIDEAERGFSFQKDGPLDMRMSSRGPSAADAVNRLKTGDLA
RIFNFLGEERHAGRIARMIEKRRAAKPFTRTLDLANAIETLVGRNPKDRIHPATRVFQALRVYVNDELGELARALLAAER
ILKPGGRLVVVTFHSLEDRMVKRFFADRAGGSAGSRHMPETHMRLPSFTPAVKGAVGPTPEEEERNPRARSAKLRAGIRT
ENPPLEDDLSLFGLPKLPETNELARS
>Mature_345_residues
ASLGGDNSQAEGAEVRHVPVLIAEVIDALKPAPGAVIVDGTFGAGGYTRRILETGADVIAIDRDPTAIEAGRAMEKEFPG
RLNLVESRFSALDEAVARMSGAGKKVDGVVLDIGVSSMQIDEAERGFSFQKDGPLDMRMSSRGPSAADAVNRLKTGDLAR
IFNFLGEERHAGRIARMIEKRRAAKPFTRTLDLANAIETLVGRNPKDRIHPATRVFQALRVYVNDELGELARALLAAERI
LKPGGRLVVVTFHSLEDRMVKRFFADRAGGSAGSRHMPETHMRLPSFTPAVKGAVGPTPEEEERNPRARSAKLRAGIRTE
NPPLEDDLSLFGLPKLPETNELARS

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=39.0532544378698, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI165377202, Length=187, Percent_Identity=41.1764705882353, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1786270, Length=313, Percent_Identity=44.408945686901, Blast_Score=232, Evalue=3e-62,
Organism=Drosophila melanogaster, GI62472493, Length=329, Percent_Identity=42.5531914893617, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28571637, Length=329, Percent_Identity=42.5531914893617, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 37502; Mature: 37371

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLGGDNSQAEGAEVRHVPVLIAEVIDALKPAPGAVIVDGTFGAGGYTRRILETGADVI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCEE
AIDRDPTAIEAGRAMEKEFPGRLNLVESRFSALDEAVARMSGAGKKVDGVVLDIGVSSMQ
EECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHH
IDEAERGFSFQKDGPLDMRMSSRGPSAADAVNRLKTGDLARIFNFLGEERHAGRIARMIE
HHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHH
KRRAAKPFTRTLDLANAIETLVGRNPKDRIHPATRVFQALRVYVNDELGELARALLAAER
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKPGGRLVVVTFHSLEDRMVKRFFADRAGGSAGSRHMPETHMRLPSFTPAVKGAVGPTP
HHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHCCCCCCCC
EEEERNPRARSAKLRAGIRTENPPLEDDLSLFGLPKLPETNELARS
CHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCHHHHHCC
>Mature Secondary Structure 
ASLGGDNSQAEGAEVRHVPVLIAEVIDALKPAPGAVIVDGTFGAGGYTRRILETGADVI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCEE
AIDRDPTAIEAGRAMEKEFPGRLNLVESRFSALDEAVARMSGAGKKVDGVVLDIGVSSMQ
EECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHH
IDEAERGFSFQKDGPLDMRMSSRGPSAADAVNRLKTGDLARIFNFLGEERHAGRIARMIE
HHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHH
KRRAAKPFTRTLDLANAIETLVGRNPKDRIHPATRVFQALRVYVNDELGELARALLAAER
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKPGGRLVVVTFHSLEDRMVKRFFADRAGGSAGSRHMPETHMRLPSFTPAVKGAVGPTP
HHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHCCCCCCCC
EEEERNPRARSAKLRAGIRTENPPLEDDLSLFGLPKLPETNELARS
CHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA