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The map label for this gene is cobO [H]

Identifier: 23502181

GI number: 23502181

Start: 1263634

End: 1264242

Strand: Reverse

Name: cobO [H]

Synonym: BR1305

Alternate gene names: 23502181

Gene position: 1264242-1263634 (Counterclockwise)

Preceding gene: 23502182

Following gene: 23502180

Centisome position: 59.98

GC content: 56.65

Gene sequence:

>609_bases
ATGACCGAGGAGGAGCTGAACGCCCGCCATGCGGACAAGATGCGCAAGAAGAAAGCCGCCCGCGACAAGATACAGGCGAC
AAAGACCGAGGAAAAAGGTCTGGTGATCGTCCATACCGGCAAGGGCAAGGGCAAATCGACGGCCGGTTTCGGCATGGTTT
TCCGTGCGCTGGGCCATGGGATGAAGATTGGCGTTGTGCAGTTCGTCAAAGGGTCGTGGGATACGGGCGAACGCTGGGTT
CTGGAGAAGTTTCCCGAGCAGGTGACGATTTCCGCACTGGGCGAAGGCTTTACCTGGGAAACGCAGGATCGCGCGCGCGA
TATCGCCATGGCGCGCGGCGCCTGGGAACAGGCCAAGGCGATGATTATGGATGAAAGTTACGATATGGTGCTCTGTGACG
AGCTTAATATCGTGCTTCGCTACGACTATCTGCCCGTCGAAGAGGTGACCGAGGTGCTGAAAGCCAAGCCGGAAATGAAG
CATGTCATCATCACGGGCCGTAATGCCAAGGACGAGTTGATCGAGGCGGCGGACCTCGTGACCGAAATGGAGATGATAAA
GCATCCTTTCCGTTCCGGTGTGAAGGCGCAGAAAGGCATTGAGTTTTGA

Upstream 100 bases:

>100_bases
AATTCCGCGCGTTTCGAGCTGGAAAATTTAAGTGTGCATCTTCAAAAATTGAATCCGGAAAGGGCGATAAATGGCTGAGA
AATCGGAAAAACTTCTTTCG

Downstream 100 bases:

>100_bases
TGATGGCTAGCTGGCAATTCTGGGCATTGATGTCGGCGGTTTTTGCCGCGCTGACGGCGATCTTCGCCAAGGTGGGCATT
CAGGGCATCAATTCGGATTT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHGMKIGVVQFVKGSWDTGERWV
LEKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVTEVLKAKPEMK
HVIITGRNAKDELIEAADLVTEMEMIKHPFRSGVKAQKGIEF

Sequences:

>Translated_202_residues
MTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHGMKIGVVQFVKGSWDTGERWV
LEKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVTEVLKAKPEMK
HVIITGRNAKDELIEAADLVTEMEMIKHPFRSGVKAQKGIEF
>Mature_201_residues
TEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHGMKIGVVQFVKGSWDTGERWVL
EKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVTEVLKAKPEMKH
VIITGRNAKDELIEAADLVTEMEMIKHPFRSGVKAQKGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=194, Percent_Identity=47.9381443298969, Blast_Score=194, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22802; Mature: 22670

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCC
MKIGVVQFVKGSWDTGERWVLEKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKA
CEEHHHHHCCCCCCCCCHHHHHHCCHHEEHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH
MIMDESYDMVLCDELNIVLRYDYLPVEEVTEVLKAKPEMKHVIITGRNAKDELIEAADLV
HHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
TEMEMIKHPFRSGVKAQKGIEF
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCC
MKIGVVQFVKGSWDTGERWVLEKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKA
CEEHHHHHCCCCCCCCCHHHHHHCCHHEEHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH
MIMDESYDMVLCDELNIVLRYDYLPVEEVTEVLKAKPEMKHVIITGRNAKDELIEAADLV
HHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
TEMEMIKHPFRSGVKAQKGIEF
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]