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The map label for this gene is slt [H]

Identifier: 23501530

GI number: 23501530

Start: 635534

End: 637492

Strand: Reverse

Name: slt [H]

Synonym: BR0643

Alternate gene names: 23501530

Gene position: 637492-635534 (Counterclockwise)

Preceding gene: 23501535

Following gene: 23501528

Centisome position: 30.24

GC content: 59.57

Gene sequence:

>1959_bases
GTGACGCCGAGGCCCCGCCCCATCGCTCCTGATCCCATGGCCACGTCCGCCGTCAGCCGGACAGATAATCCGGCCGTGAT
CGGCGGAACATTGAAAAATGGCCTCGACGCGCTTAGCGCCAAGAATGTCGCAAGCGCCATCGCTTCTCGCAACAACTTGC
CGCGCGGCTCGCTCGACCGTCAGATTCTCACCTGGGCAATTGCAACCTCCGGCATGGATGGTGTTCCCAGCACAGAGATT
GCGGCCGCAGCATCCGAACTTTCAGGATGGCCCGGCATGGCCACCTTGCGCCGGAATTCAGAACGGGCGCTTTTCAAGGA
AAATCCTTCTTCTGCAACCATCATCGCCACTTTCGGCAGCACACGTCCACAGACCACGGAAGGCATGATCGCTTTGGCAC
GCGCCTATGTGGCGACAGGCAATTCCACCAAGGCGCACCAGCTTCTCTCACCTTGGTGGACCAGGAAGCGTCTTTCATCC
GACGATGAGCAGAAGATCCTGAAAGAATTTTCGGCGATTCTCACCCGCGAGGATCACCAACGCAGGCTGCTGCACTCTCT
CTATAATGGCCGCCTGCAATCGGCCCGGCTTCTTGCCGGGCCTGCGCAGGCGCAATCTCTTTATAATGCCTATGCCGCAG
TGGCGCAGAAATCACCCAACGCCGCCAGTGCAATCGCCGCCGTGGACCGTTCCTGGCAGGCCAATCCGGTCTATCAGTTT
TTAAAAATTCGCTATCTGCGCCGCGCCGAGCGTTACAACGAGGCTGCCGAGCTTCTGTTGAAAGCGCCACGGAAGGCTTC
CGTTCTTGTCGATCCCGATGCCTGGTGGGTGGAACGGCGCATCCTGTCACGCGAACTTCTCGATCTCGGAAAGCCGCAAC
TTGCCTATCGGCTTGCCGCGGCCCATGCCGCCGAAACGCCCACCATGGCGGCGGAAGCCGAATTCCACGCGGGCTGGTAT
GCGCTTCGCGCCCTGAACCAACCGAAGCTGGCAGCGCCCCATTTTGCAAAAATCACGCAAATTTCGGCGCGCCCCATCTC
CGCTTCCCGTGCCTATTACTGGCTTGGGCGGGCAGCGGAAGCTGGTTCTGGCGGCGATGCACGCGCCTATTACCGGCGGT
CGGCGCATTTCGGCACCACTTTTTATGGCCAGCTTGCGGCCGCCAAGCTGAATGAGAAGGCTCCTGAACTCGCCTATCCC
AAGCCCACGGAAGCAGAGCGTGTGCGCTTTGCAAGCCGCCCCGCCGTGCAGGCAATCAAACGGCTGGAGCAGGTCGGTTA
TGGAAACAAGGCTGCGGCTCTTTACACACAGCTTTCGCAAGAACTCGACAGTGTGGGAGAACTCGCCCTGCTCGCCGTGA
TGGCTGAGCGGAACGACAATCATTATATGGCGCTGCGCGTCGGCAAAACGGCGGCAATGCGCGGGCTCGATGTCGGCGCA
CTTTCCCATCCGCTCGGCGCAATCCCTGCAAGCGCGAATATCAAGGGTTCCGGCAAGGCGCTTGCCTATGCCATCGCGCG
GCAGGAAAGCGAATTCAATGTCAGCGCAGTTTCAAAAGCAGGCGCGCGCGGCCTGCTGCAACTTATGCCCGCCACAGCAA
AAACGGTCGCCACACGCAACGGAATGAGCTTTTCCGCGCAGAAGCTTACGGCAGATGCGGCCTATAATGCCACGCTCGGC
GCACATTTTCTCGGTGAGCAGCTGGATCGTTTCAACGGTTCCTATGTACTCACCTTCGCCGGGTATAATGCCGGGCCGCG
CCGCGCCTCCGAATGGGTGGAGAAATATGGCGACCCGCGCGGCAAATCTGTCGAACAGGTCGTGGATTGGATTGAGCGCA
TCCCCTATTCCGAAACGCGCAATTATGTGCAGCGCGTGATGGAAAATTACGAAGTCTATAAGACCCGGCTGACTGGCCGT
GCCGATATCAAGACCGATCTGGTTTATGGGCGACGCTGA

Upstream 100 bases:

>100_bases
GATGGTTTCACTTGCCCAATCGTCGCTGCCGCCTGAAATCCCCACGCCGCTTGCGCGCCCCTTCGCGCCGACTACCACCC
ATCAATCCCCAATCAGTCTG

Downstream 100 bases:

>100_bases
TAAGTAGCTTCTCCAAAGAAACCGGGGCGGTTCCAGCATAAACCGGAGCCGCCCCCACTGGTTCAGCCAGCCTGTTTTTT
TGCGCGCCGCGTTCCTGATC

Product: transglycosylase SLT domain-containing protein

Products: 1,6-Anhydrobond [C]

Alternate protein names: Peptidoglycan lytic exotransglycosylase [H]

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MTPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAIASRNNLPRGSLDRQILTWAIATSGMDGVPSTEI
AAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTEGMIALARAYVATGNSTKAHQLLSPWWTRKRLSS
DDEQKILKEFSAILTREDHQRRLLHSLYNGRLQSARLLAGPAQAQSLYNAYAAVAQKSPNAASAIAAVDRSWQANPVYQF
LKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELLDLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWY
ALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDARAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYP
KPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGELALLAVMAERNDNHYMALRVGKTAAMRGLDVGA
LSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQLMPATAKTVATRNGMSFSAQKLTADAAYNATLG
AHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQVVDWIERIPYSETRNYVQRVMENYEVYKTRLTGR
ADIKTDLVYGRR

Sequences:

>Translated_652_residues
MTPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAIASRNNLPRGSLDRQILTWAIATSGMDGVPSTEI
AAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTEGMIALARAYVATGNSTKAHQLLSPWWTRKRLSS
DDEQKILKEFSAILTREDHQRRLLHSLYNGRLQSARLLAGPAQAQSLYNAYAAVAQKSPNAASAIAAVDRSWQANPVYQF
LKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELLDLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWY
ALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDARAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYP
KPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGELALLAVMAERNDNHYMALRVGKTAAMRGLDVGA
LSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQLMPATAKTVATRNGMSFSAQKLTADAAYNATLG
AHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQVVDWIERIPYSETRNYVQRVMENYEVYKTRLTGR
ADIKTDLVYGRR
>Mature_651_residues
TPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAIASRNNLPRGSLDRQILTWAIATSGMDGVPSTEIA
AAASELSGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTEGMIALARAYVATGNSTKAHQLLSPWWTRKRLSSD
DEQKILKEFSAILTREDHQRRLLHSLYNGRLQSARLLAGPAQAQSLYNAYAAVAQKSPNAASAIAAVDRSWQANPVYQFL
KIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELLDLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWYA
LRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDARAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYPK
PTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGELALLAVMAERNDNHYMALRVGKTAAMRGLDVGAL
SHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQLMPATAKTVATRNGMSFSAQKLTADAAYNATLGA
HFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQVVDWIERIPYSETRNYVQRVMENYEVYKTRLTGRA
DIKTDLVYGRR

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=277, Percent_Identity=29.9638989169675, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011989
- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 71170; Mature: 71039

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAIASRNNLPRGSLDR
CCCCCCCCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
QILTWAIATSGMDGVPSTEIAAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGS
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCEECCCCCEEEEEEECC
TRPQTTEGMIALARAYVATGNSTKAHQLLSPWWTRKRLSSDDEQKILKEFSAILTREDHQ
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHH
RRLLHSLYNGRLQSARLLAGPAQAQSLYNAYAAVAQKSPNAASAIAAVDRSWQANPVYQF
HHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHH
LKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELLDLGKPQLAYRLAA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
AHAAETPTMAAEAEFHAGWYALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAE
HHHCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCC
AGSGGDARAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYPKPTEAERVRFASRPAVQAIK
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHH
RLEQVGYGNKAAALYTQLSQELDSVGELALLAVMAERNDNHYMALRVGKTAAMRGLDVGA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHCCCCCCH
LSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQLMPATAKTVATRN
HHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCC
GMSFSAQKLTADAAYNATLGAHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPR
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
GKSVEQVVDWIERIPYSETRNYVQRVMENYEVYKTRLTGRADIKTDLVYGRR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
TPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAIASRNNLPRGSLDR
CCCCCCCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
QILTWAIATSGMDGVPSTEIAAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGS
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCEECCCCCEEEEEEECC
TRPQTTEGMIALARAYVATGNSTKAHQLLSPWWTRKRLSSDDEQKILKEFSAILTREDHQ
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHH
RRLLHSLYNGRLQSARLLAGPAQAQSLYNAYAAVAQKSPNAASAIAAVDRSWQANPVYQF
HHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHH
LKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELLDLGKPQLAYRLAA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
AHAAETPTMAAEAEFHAGWYALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAE
HHHCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCC
AGSGGDARAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYPKPTEAERVRFASRPAVQAIK
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHH
RLEQVGYGNKAAALYTQLSQELDSVGELALLAVMAERNDNHYMALRVGKTAAMRGLDVGA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHCCCCCCH
LSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQLMPATAKTVATRN
HHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCC
GMSFSAQKLTADAAYNATLGAHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPR
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCC
GKSVEQVVDWIERIPYSETRNYVQRVMENYEVYKTRLTGRADIKTDLVYGRR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]