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The map label for this gene is 23501454

Identifier: 23501454

GI number: 23501454

Start: 560160

End: 560813

Strand: Reverse

Name: 23501454

Synonym: BR0565

Alternate gene names: NA

Gene position: 560813-560160 (Counterclockwise)

Preceding gene: 23501457

Following gene: 23501453

Centisome position: 26.61

GC content: 57.95

Gene sequence:

>654_bases
GTGTCCTACAGTTCCTATGCCTTCGATGCCTATGGCACATTGTTCGATGTCCATTCGGCGGTGCGGCGACATGCGGACAA
GGCGGGGCCGGACGGGCGGGCCCTGTCCGAATTGTGGCGCGCAAAACAACTGGAATATTCGTGGGTTCTGAGCCTGATGG
GTGCTTATAGCGATTTCTGGAAACTGACAGAAGAATCGCTCGATTATGCCCTTGCGCACTATCCTTCCGTCGATCCGGCG
CTGCGCAACGACCTTCTCGATGCCTATTGGAAACTCGATTGCTACCCGGAAGTGCCCGCGGCGCTGAAGGCCCTGAAGGA
TCGTGGCGCACGGCTTGCCATTCTATCCAACGGCTCGCCCGCCATGCTGGAGGCGGCGGTCAGGTCTGCTGCCCTCGACG
TGCTGCTCGATGATGTCATCTCGGTCGATATGGTGAAGAAATACAAGACCTCGCTTGCGGTCTATGAGCTTATTGCCGTG
CAATGGCGGCTCTACCCTTCCACCATCTCGTTCCAGTCATCAAACCGCTGGGATGTGGCGGGCGCGGTGCGTTTTGGAAT
GCGCGGCGTGTGGATCAACCGTTCCAACGAGCCGGATGAATACAAGCAGTTTCCCCCGGCCCTCATTCTGCCAAGCCTGC
ATCTTCTGGATTGA

Upstream 100 bases:

>100_bases
AATGGCGCAATTCAGCTTCAAGGCAATGAAATATTATTGAAATCCCAGCAAGATGGGGCAGATAGTCTTTTGCTGACATT
CATGCTCCACGGAGGAAACG

Downstream 100 bases:

>100_bases
ATCACAAAAATTTGAACCCGACTTTTATCGGGATACCCCTGATATCCGCCAAAATCGTGTCGCCGGGGCAACACGCGCCA
TGGAGGAGCCTGCTCGCCTC

Product: haloacid dehalogenase

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase I; DEHCI; Halocarboxylic acid halidohydrolase I; L-2-haloacid dehalogenase I [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSYSSYAFDAYGTLFDVHSAVRRHADKAGPDGRALSELWRAKQLEYSWVLSLMGAYSDFWKLTEESLDYALAHYPSVDPA
LRNDLLDAYWKLDCYPEVPAALKALKDRGARLAILSNGSPAMLEAAVRSAALDVLLDDVISVDMVKKYKTSLAVYELIAV
QWRLYPSTISFQSSNRWDVAGAVRFGMRGVWINRSNEPDEYKQFPPALILPSLHLLD

Sequences:

>Translated_217_residues
MSYSSYAFDAYGTLFDVHSAVRRHADKAGPDGRALSELWRAKQLEYSWVLSLMGAYSDFWKLTEESLDYALAHYPSVDPA
LRNDLLDAYWKLDCYPEVPAALKALKDRGARLAILSNGSPAMLEAAVRSAALDVLLDDVISVDMVKKYKTSLAVYELIAV
QWRLYPSTISFQSSNRWDVAGAVRFGMRGVWINRSNEPDEYKQFPPALILPSLHLLD
>Mature_216_residues
SYSSYAFDAYGTLFDVHSAVRRHADKAGPDGRALSELWRAKQLEYSWVLSLMGAYSDFWKLTEESLDYALAHYPSVDPAL
RNDLLDAYWKLDCYPEVPAALKALKDRGARLAILSNGSPAMLEAAVRSAALDVLLDDVISVDMVKKYKTSLAVYELIAVQ
WRLYPSTISFQSSNRWDVAGAVRFGMRGVWINRSNEPDEYKQFPPALILPSLHLLD

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 24444; Mature: 24313

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSSYAFDAYGTLFDVHSAVRRHADKAGPDGRALSELWRAKQLEYSWVLSLMGAYSDFW
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLTEESLDYALAHYPSVDPALRNDLLDAYWKLDCYPEVPAALKALKDRGARLAILSNGSP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCH
AMLEAAVRSAALDVLLDDVISVDMVKKYKTSLAVYELIAVQWRLYPSTISFQSSNRWDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCHH
GAVRFGMRGVWINRSNEPDEYKQFPPALILPSLHLLD
HHHHHCCEEEEECCCCCCHHHHHCCCHHHCCCHHCCC
>Mature Secondary Structure 
SYSSYAFDAYGTLFDVHSAVRRHADKAGPDGRALSELWRAKQLEYSWVLSLMGAYSDFW
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLTEESLDYALAHYPSVDPALRNDLLDAYWKLDCYPEVPAALKALKDRGARLAILSNGSP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCH
AMLEAAVRSAALDVLLDDVISVDMVKKYKTSLAVYELIAVQWRLYPSTISFQSSNRWDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCHH
GAVRFGMRGVWINRSNEPDEYKQFPPALILPSLHLLD
HHHHHCCEEEEECCCCCCHHHHHCCCHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1995594 [H]