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The map label for this gene is chbR [H]

Identifier: 23100852

GI number: 23100852

Start: 3532233

End: 3533039

Strand: Direct

Name: chbR [H]

Synonym: OB3397

Alternate gene names: 23100852

Gene position: 3532233-3533039 (Clockwise)

Preceding gene: 23100848

Following gene: 23100853

Centisome position: 97.29

GC content: 36.18

Gene sequence:

>807_bases
TTGAAAACAGATAAGCAACAAGCATTAATCTCTTTATATGAAAGTAAGCACAATGAAAAAGAAAAAGTGAAATCGCATGA
GCATGATACGTATCAATTGCTATATACGCTAAAAGGCACTGGTATCTGTACATTGAACCATCAAGAGTATGCAATTGCAC
AAGATAATTTTATTATTATTCCACCTGAAACGGAACACTCCATAGCTGCATCATCAAAAATGACTGTTTTGGTGCTTGAA
TTTGAAGCAGATATTTTTCACTCAGATGTGAAAATGGAGCTAATTCCCGAGGTATTTCGATCTGCGCGTGTACAAAAACT
CAGTACATTTGATAGCAGTGAGATACGGCAACTACTTCGTAAAATGCTCTATGAACAATCCTATGGAGATAATTTATGGG
AAACGGGTATCAAAATATATATGGCAGAGCTATTTTTTATCATTGCTCGTTCTTTTCACGAACCTTCGCAAACGGATATT
AATACATTACGTGTCGAACAGCTAAAACATTATATAGATACACGCTATTTTGACATAAAAAATGCAGAAGATATCGCAGA
TCGAATGGACATGAGCAAACGTTACATACAAAGTATTTTCAAAGAATACTATAATAGCACGCCGATGCAATACTTGACCG
AAGTACGACTTGGCTTAGTGAAACAGATGCTAGTCGACACCGATAAAGATATTGTTTCCATCTGTTTTGAAGTTGGTTTC
GAATCACTATCCACCTTTTACCGATTATTTAAGAACAACGTCGGTGTACCGCCTAATATGTATCGACTTACGCAGAGAGA
ACGTTAG

Upstream 100 bases:

>100_bases
TTTACAATACCAAACAAAAACAACAAAAATTAAAAATAAACAGAAAAAATGTTATACTTAAAGCAAACGCAAATAAAGAT
AATGTAAGGGGGTATGTTTC

Downstream 100 bases:

>100_bases
GGTTTTGAAAGACTATGATTCTGTTTTTTAATTGTGTTCCGAAATTGAGAATTTGTTTCCCCTTCTAATAAGACACTCTA
TGTGGTTATGTTTACACTTA

Product: hypothetical protein

Products: NA

Alternate protein names: Chb operon repressor [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKTDKQQALISLYESKHNEKEKVKSHEHDTYQLLYTLKGTGICTLNHQEYAIAQDNFIIIPPETEHSIAASSKMTVLVLE
FEADIFHSDVKMELIPEVFRSARVQKLSTFDSSEIRQLLRKMLYEQSYGDNLWETGIKIYMAELFFIIARSFHEPSQTDI
NTLRVEQLKHYIDTRYFDIKNAEDIADRMDMSKRYIQSIFKEYYNSTPMQYLTEVRLGLVKQMLVDTDKDIVSICFEVGF
ESLSTFYRLFKNNVGVPPNMYRLTQRER

Sequences:

>Translated_268_residues
MKTDKQQALISLYESKHNEKEKVKSHEHDTYQLLYTLKGTGICTLNHQEYAIAQDNFIIIPPETEHSIAASSKMTVLVLE
FEADIFHSDVKMELIPEVFRSARVQKLSTFDSSEIRQLLRKMLYEQSYGDNLWETGIKIYMAELFFIIARSFHEPSQTDI
NTLRVEQLKHYIDTRYFDIKNAEDIADRMDMSKRYIQSIFKEYYNSTPMQYLTEVRLGLVKQMLVDTDKDIVSICFEVGF
ESLSTFYRLFKNNVGVPPNMYRLTQRER
>Mature_268_residues
MKTDKQQALISLYESKHNEKEKVKSHEHDTYQLLYTLKGTGICTLNHQEYAIAQDNFIIIPPETEHSIAASSKMTVLVLE
FEADIFHSDVKMELIPEVFRSARVQKLSTFDSSEIRQLLRKMLYEQSYGDNLWETGIKIYMAELFFIIARSFHEPSQTDI
NTLRVEQLKHYIDTRYFDIKNAEDIADRMDMSKRYIQSIFKEYYNSTPMQYLTEVRLGLVKQMLVDTDKDIVSICFEVGF
ESLSTFYRLFKNNVGVPPNMYRLTQRER

Specific function: Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presen

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788030, Length=255, Percent_Identity=22.7450980392157, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790559, Length=105, Percent_Identity=35.2380952380952, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013096
- InterPro:   IPR011051
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF07883 Cupin_2; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31611; Mature: 31611

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDKQQALISLYESKHNEKEKVKSHEHDTYQLLYTLKGTGICTLNHQEYAIAQDNFIII
CCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEECCCEEEEECCCCEEEECCCEEEE
PPETEHSIAASSKMTVLVLEFEADIFHSDVKMELIPEVFRSARVQKLSTFDSSEIRQLLR
CCCCCCHHHCCCCEEEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KMLYEQSYGDNLWETGIKIYMAELFFIIARSFHEPSQTDINTLRVEQLKHYIDTRYFDIK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
NAEDIADRMDMSKRYIQSIFKEYYNSTPMQYLTEVRLGLVKQMLVDTDKDIVSICFEVGF
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ESLSTFYRLFKNNVGVPPNMYRLTQRER
HHHHHHHHHHHCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MKTDKQQALISLYESKHNEKEKVKSHEHDTYQLLYTLKGTGICTLNHQEYAIAQDNFIII
CCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEEECCCEEEEECCCCEEEECCCEEEE
PPETEHSIAASSKMTVLVLEFEADIFHSDVKMELIPEVFRSARVQKLSTFDSSEIRQLLR
CCCCCCHHHCCCCEEEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KMLYEQSYGDNLWETGIKIYMAELFFIIARSFHEPSQTDINTLRVEQLKHYIDTRYFDIK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
NAEDIADRMDMSKRYIQSIFKEYYNSTPMQYLTEVRLGLVKQMLVDTDKDIVSICFEVGF
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ESLSTFYRLFKNNVGVPPNMYRLTQRER
HHHHHHHHHHHCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 9405618 [H]