Click here to switch to the map view.

The map label for this gene is iolC [H]

Identifier: 23100657

GI number: 23100657

Start: 3332555

End: 3333568

Strand: Reverse

Name: iolC [H]

Synonym: OB3202

Alternate gene names: 23100657

Gene position: 3333568-3332555 (Counterclockwise)

Preceding gene: 23100658

Following gene: 23100656

Centisome position: 91.82

GC content: 37.67

Gene sequence:

>1014_bases
ATGACGAATAAAGTGAAGGCATTTGGAGAAGTAATGATGCGACTCCATGTACCAGGTAATAAGAAGTTAGTGCAAACGCG
TGCGTTAGATATGTCTTTTTCGGGTACAGGAGTGAATGTGCTGACGGCTCTAGGGAGATATGGCAACCAGACTAGTCTCA
TCACCACTTTACCAGATAATAATATCGGAGAAGCATCGCTATCGTATTTGCAATCATTAGGTATTGGAACGCAAGACATT
CGTCGAGATGGGGACCATATAGGCATGTTCTTTTTAGAAGATGGTTTTGATTTGCGCCCATCCGTAGTCACATACACCAA
TAGGAAAATCAGTGCCTTTCATCAATCAGTAACTTCAGACTATGAAATGGATCGCATTTTACTAGATACAGATATGATTC
ACTTTTGTGGCATTGGGTTAGCAGTCTCTGAGAATTCGAGGGATACCATTCTTTCACTTGCTAAAAAAGCAAAGGAACGT
GGAGTTTTAGTAGTATTTGATTGTAATTATCGGCAGAAACTTTGGAAAAGTAATATTCACCGTGCGAAAAATGATTATCA
GCAAATGCTGCAGCTAAGTGATGTATGTTTTATGACAGAAAAAGACGCTATGCATATATTAGGCTACGCTACGAATGAGA
TAGAACGAAAATCACAAATCAAACACCTTATACCAAAAGTAGCAAAGGAATATGGAATTCAATCAATTGCTGGTACAATA
AGGCAGAGATTACAAGATAATAAGCATGAAATCGAAGGGTTTTTATATACAAATGCTAAATTTTATTTCTCCAAACGTTA
TGAATTTCGAATTTTCGATCGTATCGGTGGAGGAGATGGATTTGCTAGTGGTATAATGCATGGATTACGACAACAGTATT
CGAAAAAAGATACTATTCAATTTGCGATGGCAGCAGGAATATTAGCACATACGACTTATGGTGATTCGCCGATTTCCTCA
GATAAAGAAGTATGGGCATTAGTAAATAATCATGATCCCGATATAGAAAGGTAG

Upstream 100 bases:

>100_bases
CCACATGTCTATTCATCTATTATCGATGGATCTACCGGTCGTACGAGACTAGAGGATGTACAGTCTATCTATCATTTTGT
GAAAAAATTAGGAGATCAGT

Downstream 100 bases:

>100_bases
ATCAACCATGAAACTGAATTTAAGGGAAGGTTCTTTATATATTCAAGTGAAAGATATCTTGAAAGAAAGAATTATTAATG
GGCGATATAAGGTCAATGAT

Product: 2-dehydro-3-deoxygluconokinase

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTNKVKAFGEVMMRLHVPGNKKLVQTRALDMSFSGTGVNVLTALGRYGNQTSLITTLPDNNIGEASLSYLQSLGIGTQDI
RRDGDHIGMFFLEDGFDLRPSVVTYTNRKISAFHQSVTSDYEMDRILLDTDMIHFCGIGLAVSENSRDTILSLAKKAKER
GVLVVFDCNYRQKLWKSNIHRAKNDYQQMLQLSDVCFMTEKDAMHILGYATNEIERKSQIKHLIPKVAKEYGIQSIAGTI
RQRLQDNKHEIEGFLYTNAKFYFSKRYEFRIFDRIGGGDGFASGIMHGLRQQYSKKDTIQFAMAAGILAHTTYGDSPISS
DKEVWALVNNHDPDIER

Sequences:

>Translated_337_residues
MTNKVKAFGEVMMRLHVPGNKKLVQTRALDMSFSGTGVNVLTALGRYGNQTSLITTLPDNNIGEASLSYLQSLGIGTQDI
RRDGDHIGMFFLEDGFDLRPSVVTYTNRKISAFHQSVTSDYEMDRILLDTDMIHFCGIGLAVSENSRDTILSLAKKAKER
GVLVVFDCNYRQKLWKSNIHRAKNDYQQMLQLSDVCFMTEKDAMHILGYATNEIERKSQIKHLIPKVAKEYGIQSIAGTI
RQRLQDNKHEIEGFLYTNAKFYFSKRYEFRIFDRIGGGDGFASGIMHGLRQQYSKKDTIQFAMAAGILAHTTYGDSPISS
DKEVWALVNNHDPDIER
>Mature_336_residues
TNKVKAFGEVMMRLHVPGNKKLVQTRALDMSFSGTGVNVLTALGRYGNQTSLITTLPDNNIGEASLSYLQSLGIGTQDIR
RDGDHIGMFFLEDGFDLRPSVVTYTNRKISAFHQSVTSDYEMDRILLDTDMIHFCGIGLAVSENSRDTILSLAKKAKERG
VLVVFDCNYRQKLWKSNIHRAKNDYQQMLQLSDVCFMTEKDAMHILGYATNEIERKSQIKHLIPKVAKEYGIQSIAGTIR
QRLQDNKHEIEGFLYTNAKFYFSKRYEFRIFDRIGGGDGFASGIMHGLRQQYSKKDTIQFAMAAGILAHTTYGDSPISSD
KEVWALVNNHDPDIER

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=296, Percent_Identity=23.9864864864865, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 38143; Mature: 38012

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKVKAFGEVMMRLHVPGNKKLVQTRALDMSFSGTGVNVLTALGRYGNQTSLITTLPDN
CCCHHHHHHHHHHHEECCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCC
NIGEASLSYLQSLGIGTQDIRRDGDHIGMFFLEDGFDLRPSVVTYTNRKISAFHQSVTSD
CCCHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCCCCEEEECCCHHHHHHHHHCCC
YEMDRILLDTDMIHFCGIGLAVSENSRDTILSLAKKAKERGVLVVFDCNYRQKLWKSNIH
CCCCEEEECCCHHHHHCCCEEECCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHH
RAKNDYQQMLQLSDVCFMTEKDAMHILGYATNEIERKSQIKHLIPKVAKEYGIQSIAGTI
HHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
RQRLQDNKHEIEGFLYTNAKFYFSKRYEFRIFDRIGGGDGFASGIMHGLRQQYSKKDTIQ
HHHHCCCHHHCCEEEEECEEEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHH
FAMAAGILAHTTYGDSPISSDKEVWALVNNHDPDIER
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TNKVKAFGEVMMRLHVPGNKKLVQTRALDMSFSGTGVNVLTALGRYGNQTSLITTLPDN
CCHHHHHHHHHHHEECCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCC
NIGEASLSYLQSLGIGTQDIRRDGDHIGMFFLEDGFDLRPSVVTYTNRKISAFHQSVTSD
CCCHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCCCCEEEECCCHHHHHHHHHCCC
YEMDRILLDTDMIHFCGIGLAVSENSRDTILSLAKKAKERGVLVVFDCNYRQKLWKSNIH
CCCCEEEECCCHHHHHCCCEEECCCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHH
RAKNDYQQMLQLSDVCFMTEKDAMHILGYATNEIERKSQIKHLIPKVAKEYGIQSIAGTI
HHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
RQRLQDNKHEIEGFLYTNAKFYFSKRYEFRIFDRIGGGDGFASGIMHGLRQQYSKKDTIQ
HHHHCCCHHHCCEEEEECEEEEEEECEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHH
FAMAAGILAHTTYGDSPISSDKEVWALVNNHDPDIER
HHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA