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The map label for this gene is yuxJ [H]

Identifier: 23100513

GI number: 23100513

Start: 3174679

End: 3175878

Strand: Direct

Name: yuxJ [H]

Synonym: OB3058

Alternate gene names: 23100513

Gene position: 3174679-3175878 (Clockwise)

Preceding gene: 23100510

Following gene: 28563948

Centisome position: 87.44

GC content: 37.5

Gene sequence:

>1200_bases
ATGTGGTTGGCAAACTTTTTTATTAGCGGAAGCATGACAATGGTTGTTCCATTTATCTCCTTATATATTGAGTCTATGGG
AGATTTTTCTGAAGGTTACGTACAAACATGGTCAGGGCTAACGTTTGCTGTTACATTTATTACAGCTTTTATCTTTTCTC
CTATATGGGGAAGAATAGGTGATCGATACGGACGGAAGAAAATCATGATCGCCTCTGCTTTCGGAATCGGCTTTTCCGTC
TTTTTAATGGGGTTTGCCGATACCGTTTGGCAATTATTTCTTTTACGCTTGTTTATGGGAATTGTAACAGGTTTTATTCC
TATGTCACAAGCTTTTATCGCAACACAGACACCAAAGGAAGTTGCAGGAAAAGTACTTGGAACGCTTCAAACAGGTACAA
TTACTGGTTCATTAATGGGACCATTACTCGGCGGAGCTTTAGCAGATGCATTCGGATATACGAGTACATTTAAATGGGTT
GCTATCACTATCTTCATCTCTGGATTGCTCGTATTATTTGGAGTGAAGGAATTAAAAATGAAGTTCTCCAATAATGAGAA
CGACACGAAAAAGTATTCTAGAAAAGAAGTATTGCAGCATATTTTACAAAAACCCGTATTATTTGTTGTTATGTTATTAT
CTGCACTTGTTCAAATTGCTCATTTTAGCATACAACCAATTCTTTCATTATTTGTGGCAGAGATTCACGGTCCAGTAAAT
CTTGCGTTTTTTGCAGGGATTGCTTTTTCGGCTGCTGGGTTAGGTAATCTTTTAATGGCAAGGCGTTGGGGAATCATCGG
TGATAACCACGGTTATGTAAAAATACTCATCATTTTGCTATTCGCTGCGGGGTTTGTGTATTTACCAGGAATATTTGTAA
CAAATATTTGGCAGCTTGTTATTTTACGATTCCTACTTGGCTTATCTATCGGAGGGATTGTTCCATTACGAATTGCATAT
ATCCGTCAAGAAGCTCCCCTGTCTATGCAAGGAGAAGTTCTTGGTTATAATACGAGCTTACGATTTTTAGGTAATATTAT
TGGACCCGCGTTAGGTGGTACAATTGCTGCTTCTTTTGGGTTTTCTGCTGTATTTATAATAACAAGTATGTTATTAATCT
TAAGTGGAATGATCATGCTTTATGTGTGGTATCGCCATGAATATGAATCAACTAGTTCACACTCCTATTCTTCGAAGTAA

Upstream 100 bases:

>100_bases
TTCGGGTTTATGTATATTTAGATTGACGAAATAAATCGGCAAGAAAGAAGGTTCGAACATCATTCATAACAATCAAGATG
TGAAGCGCAACTTAGTCATC

Downstream 100 bases:

>100_bases
GAATTATAATCGGTGTTTCGATACGTAATACGTATCGATACAGTCTCAGGATTACTTCTAGCTTTCGAAGTTAGGAAAAA
ATTACGTTTTCACACATGCT

Product: multidrug resistance protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: ORF1 [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MWLANFFISGSMTMVVPFISLYIESMGDFSEGYVQTWSGLTFAVTFITAFIFSPIWGRIGDRYGRKKIMIASAFGIGFSV
FLMGFADTVWQLFLLRLFMGIVTGFIPMSQAFIATQTPKEVAGKVLGTLQTGTITGSLMGPLLGGALADAFGYTSTFKWV
AITIFISGLLVLFGVKELKMKFSNNENDTKKYSRKEVLQHILQKPVLFVVMLLSALVQIAHFSIQPILSLFVAEIHGPVN
LAFFAGIAFSAAGLGNLLMARRWGIIGDNHGYVKILIILLFAAGFVYLPGIFVTNIWQLVILRFLLGLSIGGIVPLRIAY
IRQEAPLSMQGEVLGYNTSLRFLGNIIGPALGGTIAASFGFSAVFIITSMLLILSGMIMLYVWYRHEYESTSSHSYSSK

Sequences:

>Translated_399_residues
MWLANFFISGSMTMVVPFISLYIESMGDFSEGYVQTWSGLTFAVTFITAFIFSPIWGRIGDRYGRKKIMIASAFGIGFSV
FLMGFADTVWQLFLLRLFMGIVTGFIPMSQAFIATQTPKEVAGKVLGTLQTGTITGSLMGPLLGGALADAFGYTSTFKWV
AITIFISGLLVLFGVKELKMKFSNNENDTKKYSRKEVLQHILQKPVLFVVMLLSALVQIAHFSIQPILSLFVAEIHGPVN
LAFFAGIAFSAAGLGNLLMARRWGIIGDNHGYVKILIILLFAAGFVYLPGIFVTNIWQLVILRFLLGLSIGGIVPLRIAY
IRQEAPLSMQGEVLGYNTSLRFLGNIIGPALGGTIAASFGFSAVFIITSMLLILSGMIMLYVWYRHEYESTSSHSYSSK
>Mature_399_residues
MWLANFFISGSMTMVVPFISLYIESMGDFSEGYVQTWSGLTFAVTFITAFIFSPIWGRIGDRYGRKKIMIASAFGIGFSV
FLMGFADTVWQLFLLRLFMGIVTGFIPMSQAFIATQTPKEVAGKVLGTLQTGTITGSLMGPLLGGALADAFGYTSTFKWV
AITIFISGLLVLFGVKELKMKFSNNENDTKKYSRKEVLQHILQKPVLFVVMLLSALVQIAHFSIQPILSLFVAEIHGPVN
LAFFAGIAFSAAGLGNLLMARRWGIIGDNHGYVKILIILLFAAGFVYLPGIFVTNIWQLVILRFLLGLSIGGIVPLRIAY
IRQEAPLSMQGEVLGYNTSLRFLGNIIGPALGGTIAASFGFSAVFIITSMLLILSGMIMLYVWYRHEYESTSSHSYSSK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=384, Percent_Identity=36.9791666666667, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082404, Length=344, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161078541, Length=372, Percent_Identity=22.0430107526882, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43840; Mature: 43840

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLANFFISGSMTMVVPFISLYIESMGDFSEGYVQTWSGLTFAVTFITAFIFSPIWGRIG
CCHHHEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DRYGRKKIMIASAFGIGFSVFLMGFADTVWQLFLLRLFMGIVTGFIPMSQAFIATQTPKE
HHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VAGKVLGTLQTGTITGSLMGPLLGGALADAFGYTSTFKWVAITIFISGLLVLFGVKELKM
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KFSNNENDTKKYSRKEVLQHILQKPVLFVVMLLSALVQIAHFSIQPILSLFVAEIHGPVN
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LAFFAGIAFSAAGLGNLLMARRWGIIGDNHGYVKILIILLFAAGFVYLPGIFVTNIWQLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRFLLGLSIGGIVPLRIAYIRQEAPLSMQGEVLGYNTSLRFLGNIIGPALGGTIAASFG
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCHHHHHHHH
FSAVFIITSMLLILSGMIMLYVWYRHEYESTSSHSYSSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10568751; 7961491 [H]