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The map label for this gene is dppC [H]

Identifier: 23100424

GI number: 23100424

Start: 3078730

End: 3079683

Strand: Reverse

Name: dppC [H]

Synonym: OB2969

Alternate gene names: 23100424

Gene position: 3079683-3078730 (Counterclockwise)

Preceding gene: 23100425

Following gene: 23100423

Centisome position: 84.83

GC content: 41.61

Gene sequence:

>954_bases
ATGAGTTCAAATGAAAACAATACACATAAAACCCCTTCTGCAGTTCCTGATGAATGGTTTGCATGGAAAGGAAAAGATAC
GTTGGAAGCAGAGTCTGTTTCCAGACCTTCTCTTTCCTATTGGCAAGATGCCTGGAAAAGGCTGGTTAAAAATAAAATGG
CAATGCTCGGTTTGATATTCTTAGTGTTACTTTCAGTCATGGCAATATTTGGGCCAATGATTTCACCATATGAAGTTAAT
AAACAAGACTTGCCCAATCAGTATCAGCCACCTTCCAGTGAGCACTGGTTTGGTACAGATAGTGCTGGTAGGGATGTATT
TACACGAACATGGTATGGTGCTCGAATCTCTCTGTTTGTTGGATTAATGGCAGCACTCATCGATGTTACGGTAGGAATTA
TTTGGGGTGGTATCTCCGGATATAAAGACGGTCGCACAGATAATGTGATGATGCGTATTATTGAGATATTATACGGTTTG
CCGTATTTATTAGTTGTTATTTTACTTCTGGTGGTATTAGGACCAAGCTTAGGTACGATAATACTTGCTCTGACGATTAC
CGGCTGGGTTGGGATGGCCCGAATTGTGCGAGGACAGGTCTTACAAATTAAAAATTATGAATTTGTCCTCGCTTCACGGG
CATTTGGTACAAAGTCATCGAGAATTATCCGGCGAAATTTATTGCCAAACACGATGGGACCGATTATTGTCCAAATGACA
TTAACCGTTCCATCTGCCATTTTTGCCGAAGCTTTCCTGAGTTTTATTGGACTTGGAATCCAAGCTCCTTTTGCAAGTTG
GGGTGTGATGGCCAACGATTCATTAGGTGCGATTCTATCCGGTAACTGGTGGACGCTGTTCTTCCCGGCCTTCTTTATAT
CTTTTACGATGTTTGCGTTTAATGTACTTGGAGATGGACTTCAGGATGCATTGGATCCGAAATTAAGGAAGTAG

Upstream 100 bases:

>100_bases
TCTATAGTGCTTTTCTAATTTTTATGCTTTTTCTTGTAGATATTGCATATGGAATCCTCGATCCTCGAATAAAAATGAAT
AGTAAGGGAGGGGAAGTGTC

Downstream 100 bases:

>100_bases
GTGAACCATTTGGACAAAATACTCGAAGTGAAAGATCTTCATGTGACGTTTACAACCTATGGTGGTTCTGTCCAGGCTGT
ACGTGGAGTAAATTTTCATT

Product: dipeptide ABC transporter permease

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSSNENNTHKTPSAVPDEWFAWKGKDTLEAESVSRPSLSYWQDAWKRLVKNKMAMLGLIFLVLLSVMAIFGPMISPYEVN
KQDLPNQYQPPSSEHWFGTDSAGRDVFTRTWYGARISLFVGLMAALIDVTVGIIWGGISGYKDGRTDNVMMRIIEILYGL
PYLLVVILLLVVLGPSLGTIILALTITGWVGMARIVRGQVLQIKNYEFVLASRAFGTKSSRIIRRNLLPNTMGPIIVQMT
LTVPSAIFAEAFLSFIGLGIQAPFASWGVMANDSLGAILSGNWWTLFFPAFFISFTMFAFNVLGDGLQDALDPKLRK

Sequences:

>Translated_317_residues
MSSNENNTHKTPSAVPDEWFAWKGKDTLEAESVSRPSLSYWQDAWKRLVKNKMAMLGLIFLVLLSVMAIFGPMISPYEVN
KQDLPNQYQPPSSEHWFGTDSAGRDVFTRTWYGARISLFVGLMAALIDVTVGIIWGGISGYKDGRTDNVMMRIIEILYGL
PYLLVVILLLVVLGPSLGTIILALTITGWVGMARIVRGQVLQIKNYEFVLASRAFGTKSSRIIRRNLLPNTMGPIIVQMT
LTVPSAIFAEAFLSFIGLGIQAPFASWGVMANDSLGAILSGNWWTLFFPAFFISFTMFAFNVLGDGLQDALDPKLRK
>Mature_316_residues
SSNENNTHKTPSAVPDEWFAWKGKDTLEAESVSRPSLSYWQDAWKRLVKNKMAMLGLIFLVLLSVMAIFGPMISPYEVNK
QDLPNQYQPPSSEHWFGTDSAGRDVFTRTWYGARISLFVGLMAALIDVTVGIIWGGISGYKDGRTDNVMMRIIEILYGLP
YLLVVILLLVVLGPSLGTIILALTITGWVGMARIVRGQVLQIKNYEFVLASRAFGTKSSRIIRRNLLPNTMGPIIVQMTL
TVPSAIFAEAFLSFIGLGIQAPFASWGVMANDSLGAILSGNWWTLFFPAFFISFTMFAFNVLGDGLQDALDPKLRK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=298, Percent_Identity=43.9597315436242, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI1787054, Length=300, Percent_Identity=38, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1787760, Length=256, Percent_Identity=39.453125, Blast_Score=193, Evalue=9e-51,
Organism=Escherichia coli, GI1789964, Length=296, Percent_Identity=39.527027027027, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=35.655737704918, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1787549, Length=276, Percent_Identity=30.0724637681159, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=32.1739130434783, Blast_Score=120, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35186; Mature: 35055

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNENNTHKTPSAVPDEWFAWKGKDTLEAESVSRPSLSYWQDAWKRLVKNKMAMLGLIF
CCCCCCCCCCCCCCCCCCHHEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVLLSVMAIFGPMISPYEVNKQDLPNQYQPPSSEHWFGTDSAGRDVFTRTWYGARISLFV
HHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GLMAALIDVTVGIIWGGISGYKDGRTDNVMMRIIEILYGLPYLLVVILLLVVLGPSLGTI
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
ILALTITGWVGMARIVRGQVLQIKNYEFVLASRAFGTKSSRIIRRNLLPNTMGPIIVQMT
HHHHHHHHHHHHHHHHHCHHEEECCCEEEEEEHHCCCCHHHHHHHHCCCCCCCCEEEEEH
LTVPSAIFAEAFLSFIGLGIQAPFASWGVMANDSLGAILSGNWWTLFFPAFFISFTMFAF
HHHHHHHHHHHHHHHHHCCCCCCHHHCCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHH
NVLGDGLQDALDPKLRK
HHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SSNENNTHKTPSAVPDEWFAWKGKDTLEAESVSRPSLSYWQDAWKRLVKNKMAMLGLIF
CCCCCCCCCCCCCCCCCHHEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVLLSVMAIFGPMISPYEVNKQDLPNQYQPPSSEHWFGTDSAGRDVFTRTWYGARISLFV
HHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GLMAALIDVTVGIIWGGISGYKDGRTDNVMMRIIEILYGLPYLLVVILLLVVLGPSLGTI
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
ILALTITGWVGMARIVRGQVLQIKNYEFVLASRAFGTKSSRIIRRNLLPNTMGPIIVQMT
HHHHHHHHHHHHHHHHHCHHEEECCCEEEEEEHHCCCCHHHHHHHHCCCCCCCCEEEEEH
LTVPSAIFAEAFLSFIGLGIQAPFASWGVMANDSLGAILSGNWWTLFFPAFFISFTMFAF
HHHHHHHHHHHHHHHHHCCCCCCHHHCCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHH
NVLGDGLQDALDPKLRK
HHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377; 3145906 [H]