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The map label for this gene is tagD [H]

Identifier: 23100363

GI number: 23100363

Start: 2997095

End: 2997496

Strand: Direct

Name: tagD [H]

Synonym: OB2908

Alternate gene names: 23100363

Gene position: 2997095-2997496 (Clockwise)

Preceding gene: 23100361

Following gene: 23100364

Centisome position: 82.55

GC content: 29.85

Gene sequence:

>402_bases
TTGGAGGGGAAAAATATTACTACCGTCTTAACATATGGTACATTTGACATGTTACATATTGGACATATTAATATACTTAA
ACGAGCCAAAAGTTTAGGTGATTATTTAATAGTAGGAATTTCAACAGATGAATTCAATACATTGAAATCTAAAAAATCTT
ACTATTCATATCCAGATCGTAAACGAATTGTAGAAGCCATACGTTATGTGGATAAAGTGATTCCTGAATCCACTTGGGAA
CAAAAGTTAGAAGATATTAAGAAATATAATGTCGATTATTTTGTAATGGGAAGTGATTGGGAAGGTAAATTTGATTATTT
GAATTCGTATTGTGAAGTAATATACTTATCGAGAACAGAAGGTATATCAACTTCCAAGATAAAAGATGACTTCTCTCAGT
AA

Upstream 100 bases:

>100_bases
ATTAAATTGTCAAATTTTTATCCAAAAACAAGAAATTTTTCTATAATTATATTGTAGGTTTAGTCCATATAGTTATATAA
TAAAGAAATAAGTGTTTTAC

Downstream 100 bases:

>100_bases
ATTACCATATTAGCCAATTTCCGACAAATTACATTTGAAATGTAATTTTAAATTTACGTAAAGTTCCGTTCGTAGTACAA
TAAAATATGGTTGTCAAGAA

Product: glycerol-3-phosphate cytidylyltransferase

Products: NA

Alternate protein names: GCT; Gro-PCT; CDP-glycerol pyrophosphorylase; Teichoic acid biosynthesis protein D [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MEGKNITTVLTYGTFDMLHIGHINILKRAKSLGDYLIVGISTDEFNTLKSKKSYYSYPDRKRIVEAIRYVDKVIPESTWE
QKLEDIKKYNVDYFVMGSDWEGKFDYLNSYCEVIYLSRTEGISTSKIKDDFSQ

Sequences:

>Translated_133_residues
MEGKNITTVLTYGTFDMLHIGHINILKRAKSLGDYLIVGISTDEFNTLKSKKSYYSYPDRKRIVEAIRYVDKVIPESTWE
QKLEDIKKYNVDYFVMGSDWEGKFDYLNSYCEVIYLSRTEGISTSKIKDDFSQ
>Mature_133_residues
MEGKNITTVLTYGTFDMLHIGHINILKRAKSLGDYLIVGISTDEFNTLKSKKSYYSYPDRKRIVEAIRYVDKVIPESTWE
QKLEDIKKYNVDYFVMGSDWEGKFDYLNSYCEVIYLSRTEGISTSKIKDDFSQ

Specific function: Provides activated glycerol phosphate for teichoic acid synthesis, via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF [H]

COG id: COG0615

COG function: function code MI; Cytidylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505651, Length=131, Percent_Identity=35.8778625954198, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI296841136, Length=131, Percent_Identity=35.8778625954198, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193203447, Length=121, Percent_Identity=33.8842975206612, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509873, Length=121, Percent_Identity=33.8842975206612, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550974, Length=124, Percent_Identity=36.2903225806452, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550973, Length=124, Percent_Identity=36.2903225806452, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550975, Length=124, Percent_Identity=36.2903225806452, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR006409
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.39 [H]

Molecular weight: Translated: 15553; Mature: 15553

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGKNITTVLTYGTFDMLHIGHINILKRAKSLGDYLIVGISTDEFNTLKSKKSYYSYPDR
CCCCEEEEEEEECCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCHHHCCCCCH
KRIVEAIRYVDKVIPESTWEQKLEDIKKYNVDYFVMGSDWEGKFDYLNSYCEVIYLSRTE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHEEEEECCC
GISTSKIKDDFSQ
CCCHHHHHHHCCC
>Mature Secondary Structure
MEGKNITTVLTYGTFDMLHIGHINILKRAKSLGDYLIVGISTDEFNTLKSKKSYYSYPDR
CCCCEEEEEEEECCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCHHHCCCCCH
KRIVEAIRYVDKVIPESTWEQKLEDIKKYNVDYFVMGSDWEGKFDYLNSYCEVIYLSRTE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHEEEEECCC
GISTSKIKDDFSQ
CCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 8393871; 9384377; 9182537; 11487587; 10508782 [H]