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The map label for this gene is nagA [H]

Identifier: 23100362

GI number: 23100362

Start: 2995699

End: 2996874

Strand: Reverse

Name: nagA [H]

Synonym: OB2907

Alternate gene names: 23100362

Gene position: 2996874-2995699 (Counterclockwise)

Preceding gene: 23100365

Following gene: 23100358

Centisome position: 82.55

GC content: 40.82

Gene sequence:

>1176_bases
ATGGGGAATGATGCAGTTTGGATTAAAAAAATAAAAACAATCTATATGGAAGATAAACAAGTCATGAACGCTGGATTATT
ATTAAAAAACGGAAAAATTGATCGATTTATTTCTGCGGAAGAGCATTTTGAGCCAACAGAAGATACGGAAATAATTGATG
CAAAATACGAATGGAGTGCAATCCCAGGGTTTATTGATGGGCATATTCATGGCGGTTATGGCGTAGACGTGATGGATGCG
AAGGAGGATACATTACTCCGATTAGCAGAGAATCTTCCTGGTGAAGGTACGACAAGTTTTTTGGCTACGACAATTACCCA
ATCACCTGAAGAGATTGAAAAAGCTCTTTTGAATGTAGATTCGTTTGACAATAAACCTGGTATAGCAGAAATGGTAGGTG
TTCACCTGGAAGGACCATTTGTCGAAGTGTCGAAAGCCGGGGCACAACCGAAAGAGTATATTGCAGAACCGAATTTAGAT
CAATTTCGACATTGGCAGCATGCATCTGGAAATAGTATTCGCACCATTACAATGGCACCAGAGCATGATGTGGATGGGGA
ATTCATTGAAAGCTTGTATCATTCAGGGGTAAATGTTTCAGCTGGCCATACAGATGCTTCATTCGCTCAAATGAAAACAG
CTGTAAATCAAGGAGTTCGCCAATTAACGCATTTATGTAATGCGATGAACGGTATTCACCACCGTGATATAGGCGCGGTC
GGAGCAGCTTTTCAATTAGAAGATCTACGTGCTGAATTAATCACAGATGAAGTGCATGTGGTACCAGAGATGATGCAGTT
AATTTACGATTCCATGGGAGCAGAACGAATTATTATTATTACAGATGCGATGCGCGCAAAAGGATTAGAAGACGGAGATT
ATGAATTAGGCGGTCAACCTGTAACAGTAAAAGAGGGAAGAGCAACACTTGAAAATGGTAGTCTAGCTGGAAGTGTGCTG
CGAATGATCGATGGCGTCAAGAATATGCTAGATTTAAACGGCGTAGAAATAGAAGACATTGTCCGAATGGCTTCTGTAAA
CCCGGCTAAGCAAGTTGGCATTTTTGATCAGAAGGGAAGCATTGATGTAGGAAAGGATGCAGATATTCTCCTTGTGAATG
ATCAAATGGACATTGAATATACGATATGCCGTGGAGAAACGGCTTACCGTAAGTAA

Upstream 100 bases:

>100_bases
GGAAATATAGACAGAAATCTTTTTTGTTTACATCTTAACGTATATAATAGTGGTTAATGATATACATAATGTGAGGTAAT
GAATGGGAGTGTATTGAGTC

Downstream 100 bases:

>100_bases
TAGAGGAGTCTTGATCAAACGTTTGATTAAGGCTGTAAATAGGGGGAAGTTAATTAGAGGCTCACTGCTGAACTAACCAC
CTATTAAATTTACGATGAAG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MGNDAVWIKKIKTIYMEDKQVMNAGLLLKNGKIDRFISAEEHFEPTEDTEIIDAKYEWSAIPGFIDGHIHGGYGVDVMDA
KEDTLLRLAENLPGEGTTSFLATTITQSPEEIEKALLNVDSFDNKPGIAEMVGVHLEGPFVEVSKAGAQPKEYIAEPNLD
QFRHWQHASGNSIRTITMAPEHDVDGEFIESLYHSGVNVSAGHTDASFAQMKTAVNQGVRQLTHLCNAMNGIHHRDIGAV
GAAFQLEDLRAELITDEVHVVPEMMQLIYDSMGAERIIIITDAMRAKGLEDGDYELGGQPVTVKEGRATLENGSLAGSVL
RMIDGVKNMLDLNGVEIEDIVRMASVNPAKQVGIFDQKGSIDVGKDADILLVNDQMDIEYTICRGETAYRK

Sequences:

>Translated_391_residues
MGNDAVWIKKIKTIYMEDKQVMNAGLLLKNGKIDRFISAEEHFEPTEDTEIIDAKYEWSAIPGFIDGHIHGGYGVDVMDA
KEDTLLRLAENLPGEGTTSFLATTITQSPEEIEKALLNVDSFDNKPGIAEMVGVHLEGPFVEVSKAGAQPKEYIAEPNLD
QFRHWQHASGNSIRTITMAPEHDVDGEFIESLYHSGVNVSAGHTDASFAQMKTAVNQGVRQLTHLCNAMNGIHHRDIGAV
GAAFQLEDLRAELITDEVHVVPEMMQLIYDSMGAERIIIITDAMRAKGLEDGDYELGGQPVTVKEGRATLENGSLAGSVL
RMIDGVKNMLDLNGVEIEDIVRMASVNPAKQVGIFDQKGSIDVGKDADILLVNDQMDIEYTICRGETAYRK
>Mature_390_residues
GNDAVWIKKIKTIYMEDKQVMNAGLLLKNGKIDRFISAEEHFEPTEDTEIIDAKYEWSAIPGFIDGHIHGGYGVDVMDAK
EDTLLRLAENLPGEGTTSFLATTITQSPEEIEKALLNVDSFDNKPGIAEMVGVHLEGPFVEVSKAGAQPKEYIAEPNLDQ
FRHWQHASGNSIRTITMAPEHDVDGEFIESLYHSGVNVSAGHTDASFAQMKTAVNQGVRQLTHLCNAMNGIHHRDIGAVG
AAFQLEDLRAELITDEVHVVPEMMQLIYDSMGAERIIIITDAMRAKGLEDGDYELGGQPVTVKEGRATLENGSLAGSVLR
MIDGVKNMLDLNGVEIEDIVRMASVNPAKQVGIFDQKGSIDVGKDADILLVNDQMDIEYTICRGETAYRK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=426, Percent_Identity=28.4037558685446, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI224922791, Length=422, Percent_Identity=28.436018957346, Blast_Score=161, Evalue=8e-40,
Organism=Escherichia coli, GI1786892, Length=329, Percent_Identity=29.7872340425532, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553768, Length=343, Percent_Identity=33.2361516034985, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19920392, Length=388, Percent_Identity=32.2164948453608, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=31.4214463840399, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42940; Mature: 42809

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNDAVWIKKIKTIYMEDKQVMNAGLLLKNGKIDRFISAEEHFEPTEDTEIIDAKYEWSA
CCCCHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCEECHHHCCCCCCCCEEEECCEECCC
IPGFIDGHIHGGYGVDVMDAKEDTLLRLAENLPGEGTTSFLATTITQSPEEIEKALLNVD
CCCCCCCEEECCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCC
SFDNKPGIAEMVGVHLEGPFVEVSKAGAQPKEYIAEPNLDQFRHWQHASGNSIRTITMAP
CCCCCCCHHHHHEEECCCCEEEHHHCCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEEECC
EHDVDGEFIESLYHSGVNVSAGHTDASFAQMKTAVNQGVRQLTHLCNAMNGIHHRDIGAV
CCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
GAAFQLEDLRAELITDEVHVVPEMMQLIYDSMGAERIIIITDAMRAKGLEDGDYELGGQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCCCCCCEE
VTVKEGRATLENGSLAGSVLRMIDGVKNMLDLNGVEIEDIVRMASVNPAKQVGIFDQKGS
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHCCCCCCCCC
IDVGKDADILLVNDQMDIEYTICRGETAYRK
CCCCCCCCEEEEECCCCEEEEEECCCHHCCC
>Mature Secondary Structure 
GNDAVWIKKIKTIYMEDKQVMNAGLLLKNGKIDRFISAEEHFEPTEDTEIIDAKYEWSA
CCCHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCEECHHHCCCCCCCCEEEECCEECCC
IPGFIDGHIHGGYGVDVMDAKEDTLLRLAENLPGEGTTSFLATTITQSPEEIEKALLNVD
CCCCCCCEEECCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCC
SFDNKPGIAEMVGVHLEGPFVEVSKAGAQPKEYIAEPNLDQFRHWQHASGNSIRTITMAP
CCCCCCCHHHHHEEECCCCEEEHHHCCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEEECC
EHDVDGEFIESLYHSGVNVSAGHTDASFAQMKTAVNQGVRQLTHLCNAMNGIHHRDIGAV
CCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
GAAFQLEDLRAELITDEVHVVPEMMQLIYDSMGAERIIIITDAMRAKGLEDGDYELGGQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCCCCCCEE
VTVKEGRATLENGSLAGSVLRMIDGVKNMLDLNGVEIEDIVRMASVNPAKQVGIFDQKGS
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHCCCCCCCCC
IDVGKDADILLVNDQMDIEYTICRGETAYRK
CCCCCCCCEEEEECCCCEEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]