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The map label for this gene is lytE [H]

Identifier: 23100357

GI number: 23100357

Start: 2990504

End: 2991583

Strand: Direct

Name: lytE [H]

Synonym: OB2902

Alternate gene names: 23100357

Gene position: 2990504-2991583 (Clockwise)

Preceding gene: 23100328

Following gene: 23100359

Centisome position: 82.37

GC content: 35.46

Gene sequence:

>1080_bases
ATGGCAAATAAGAAAATCTTTTTTTCTGTGACAGCAAGTGCAGTAGTAGCATCAGCATTTTTTGCAGTAGATGAAGCAGA
AGCAGCATCGCACAAAGTACAATCTGGAGACTCTTTATGGAAGATTGCACAGCAATATGGCACATCTGTTTCAACTTTAA
AGTCTATTAATAATTTATCTACGGATGTTATTTATCCAAATCAAGTATTGAAAACAAGTAAGTCTAGTTCAGGGAATTCC
AATAACTCAAACTCTGGTAATTCCGGTTCTAGCTCAAGTAATTCAAATAACTCCACCTACACGGTTAAACGTGGAGACAC
ATTAAGCGGAATTGCTTCTAAGCACGGTATTTCATTATCTAATTTGATGAAGTGGAATAACCTATCAACTACATTAATTT
ATCCTGGTGATAAATTTGTCGTAAGTAAAAATGGTTCAAGTAATTCCGGATCAAATAACTCCGGTTCTAACTCAGGAAAT
TCAAATAGTGGCAATTCTAATTCTGGAAGCTCAAAAGTACATTCAGTTAAATCAGGTGATACATTATCCGCGCTTGCGTA
TAAGTACAATACAACTGTATCGAATTTGAAAAAATGGAATAACTTAAACTCCAGCCTTATCTATGTTGGACAGAAATTAA
AGGTTTCTTCAAGTGGAAGCAGTGGCAATAATAATAGTAATAATGGCGGTAGTGATTCTTCTAATGTAGATGTTGATTAC
AATGTAGATAAATTAATTAGCACAGCAAAAAGCTTAAACGGAACTCCTTACGTATGGGGAGGATCTACACCAAGTGGATT
TGACTGCAGTGGGTTCATCTATCACGTATATAATAAAGCAGGCAAAGACATTTCTCGTACTTCCAGCCAAGGATATTTCG
ATCGTTCCTACTATGTAAATTCACCACAAAAAGGTGATTTGGTATTCTTCAAGAATACGTATAAATCTGGTATTTCCCAC
TTAGGAATTTACATTGGCAATAATCAATTCATCCACGCAGGATCAAGCGGCGTACAAATTACTAGTCTAGATAATAGCTA
CTGGAGCAAGCACTTCGATAGCTTCAAACGTTTTTATTAA

Upstream 100 bases:

>100_bases
ATATCCTGACTACCTCAATTTACCTACCTACTAAATTCATGAGGAAGTCTACTAAAATTAAAATCCTAACATTATTAATC
TCAACTGAGGGGGACTACAA

Downstream 100 bases:

>100_bases
TATGATATGAACTAAGTGTGGTTAGGACATAACAAAAAATATTAGTCAAAAGACGAATGAAAGCTAAAATAAGCGTAAGA
AATATACGGAGACTCCTTGA

Product: peptidoglycan hydrolase

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP33; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytE; Phosphatase-associated protein papQ [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MANKKIFFSVTASAVVASAFFAVDEAEAASHKVQSGDSLWKIAQQYGTSVSTLKSINNLSTDVIYPNQVLKTSKSSSGNS
NNSNSGNSGSSSSNSNNSTYTVKRGDTLSGIASKHGISLSNLMKWNNLSTTLIYPGDKFVVSKNGSSNSGSNNSGSNSGN
SNSGNSNSGSSKVHSVKSGDTLSALAYKYNTTVSNLKKWNNLNSSLIYVGQKLKVSSSGSSGNNNSNNGGSDSSNVDVDY
NVDKLISTAKSLNGTPYVWGGSTPSGFDCSGFIYHVYNKAGKDISRTSSQGYFDRSYYVNSPQKGDLVFFKNTYKSGISH
LGIYIGNNQFIHAGSSGVQITSLDNSYWSKHFDSFKRFY

Sequences:

>Translated_359_residues
MANKKIFFSVTASAVVASAFFAVDEAEAASHKVQSGDSLWKIAQQYGTSVSTLKSINNLSTDVIYPNQVLKTSKSSSGNS
NNSNSGNSGSSSSNSNNSTYTVKRGDTLSGIASKHGISLSNLMKWNNLSTTLIYPGDKFVVSKNGSSNSGSNNSGSNSGN
SNSGNSNSGSSKVHSVKSGDTLSALAYKYNTTVSNLKKWNNLNSSLIYVGQKLKVSSSGSSGNNNSNNGGSDSSNVDVDY
NVDKLISTAKSLNGTPYVWGGSTPSGFDCSGFIYHVYNKAGKDISRTSSQGYFDRSYYVNSPQKGDLVFFKNTYKSGISH
LGIYIGNNQFIHAGSSGVQITSLDNSYWSKHFDSFKRFY
>Mature_358_residues
ANKKIFFSVTASAVVASAFFAVDEAEAASHKVQSGDSLWKIAQQYGTSVSTLKSINNLSTDVIYPNQVLKTSKSSSGNSN
NSNSGNSGSSSSNSNNSTYTVKRGDTLSGIASKHGISLSNLMKWNNLSTTLIYPGDKFVVSKNGSSNSGSNNSGSNSGNS
NSGNSNSGSSKVHSVKSGDTLSALAYKYNTTVSNLKKWNNLNSSLIYVGQKLKVSSSGSSGNNNSNNGGSDSSNVDVDYN
VDKLISTAKSLNGTPYVWGGSTPSGFDCSGFIYHVYNKAGKDISRTSSQGYFDRSYYVNSPQKGDLVFFKNTYKSGISHL
GIYIGNNQFIHAGSSGVQITSLDNSYWSKHFDSFKRFY

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=115, Percent_Identity=40.8695652173913, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786421, Length=111, Percent_Identity=36.9369369369369, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788501, Length=126, Percent_Identity=38.8888888888889, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788001, Length=112, Percent_Identity=41.9642857142857, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786405, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 38200; Mature: 38069

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKKIFFSVTASAVVASAFFAVDEAEAASHKVQSGDSLWKIAQQYGTSVSTLKSINNLS
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCC
TDVIYPNQVLKTSKSSSGNSNNSNSGNSGSSSSNSNNSTYTVKRGDTLSGIASKHGISLS
CCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCHH
NLMKWNNLSTTLIYPGDKFVVSKNGSSNSGSNNSGSNSGNSNSGNSNSGSSKVHSVKSGD
HHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
TLSALAYKYNTTVSNLKKWNNLNSSLIYVGQKLKVSSSGSSGNNNSNNGGSDSSNVDVDY
CCEEEEEEECCHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEC
NVDKLISTAKSLNGTPYVWGGSTPSGFDCSGFIYHVYNKAGKDISRTSSQGYFDRSYYVN
CHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHEEEHHHCCCCHHHCCCCCCCCCEEEEC
SPQKGDLVFFKNTYKSGISHLGIYIGNNQFIHAGSSGVQITSLDNSYWSKHFDSFKRFY
CCCCCCEEEEECHHHCCCCEEEEEECCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANKKIFFSVTASAVVASAFFAVDEAEAASHKVQSGDSLWKIAQQYGTSVSTLKSINNLS
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCC
TDVIYPNQVLKTSKSSSGNSNNSNSGNSGSSSSNSNNSTYTVKRGDTLSGIASKHGISLS
CCEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCCHH
NLMKWNNLSTTLIYPGDKFVVSKNGSSNSGSNNSGSNSGNSNSGNSNSGSSKVHSVKSGD
HHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
TLSALAYKYNTTVSNLKKWNNLNSSLIYVGQKLKVSSSGSSGNNNSNNGGSDSSNVDVDY
CCEEEEEEECCHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEC
NVDKLISTAKSLNGTPYVWGGSTPSGFDCSGFIYHVYNKAGKDISRTSSQGYFDRSYYVN
CHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHEEEHHHCCCCHHHCCCCCCCCCEEEEC
SPQKGDLVFFKNTYKSGISHLGIYIGNNQFIHAGSSGVQITSLDNSYWSKHFDSFKRFY
CCCCCCEEEEECHHHCCCCEEEEEECCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457885; 9579061; 9384377; 8045898 [H]