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The map label for this gene is des [H]

Identifier: 23100307

GI number: 23100307

Start: 2936410

End: 2937459

Strand: Reverse

Name: des [H]

Synonym: OB2852

Alternate gene names: 23100307

Gene position: 2937459-2936410 (Counterclockwise)

Preceding gene: 23100312

Following gene: 23100306

Centisome position: 80.91

GC content: 37.81

Gene sequence:

>1050_bases
ATGAGTAAACAAAAACAAGCGCAATTAAGAAAAAGTGTTTCCGCCTTTGCAAAGTCAGATAAACGGACGAGCATCATTCA
ATTAATCAATTCTATTTTGCCGTTCTTTCTATTATGGTTTTTAGCATATCAGAGTCTTTCTATATCCATTTGGTTATCAT
TAGGCGTATCAGTTATTGCAGCGGGATTTGTTGTCCGTATCTTTATCATTTTCCATGATTGTACACATATGTCATTCTTT
AAAAATGCAAAAGCAAACAGAATTGTTGGTACGATAACAGGGATTATCACGCATTTTGCTTTTGAAAAATGGAAACGGGA
TCATGCAATTCACCATGCGACAAGTAGTAATTTAGATAAACGTGGAACTGGTGACGTGTGGGTTATGACAGTGGACGAGT
ATACAGAAGCTTCCTTTTGGGGGAGACTTTCTTACAGGCTTTACCGTAATCCAATTATTATGTTTGGATTAGGTCCGGCT
TATTTATTCTTGATTTCCAACCGATTTAATCGAAAAGGTGCAAAACGTAAAGAGCGCTGGAATACATATCTCATTAATTT
CTCCATCGTAGCTATTTATGGTTTGTTGATTTGGGCTATTGGCTGGCAGGCGTTCTTGATCGTACAATTACCGATTCTGT
TTATTGCAGGAGCAGCGGGAATCTGGTTATTCTATGTGCAGCATCAGTTTGAAGATTCCTATTTTGAAAATGAAGATGAG
TGGGATTATGTAAAAGCAGCGGTTGATGGGAGTTCCTATTATAAGCTACCAAAGGCAATTGAGTGGATAACAGGGAGTAT
TGGTTATCATCATGTGCACCATCTAAGTCCAAGGGTGCCAAACTACCACTTGGAGAAAGCGCATGAGTCGACACCGCCAT
TGCACAAAGCAACAACAATCACGTTATTAACAAGCTTGCAATCACTCCGTTTTCGTTTGTATGATGAGAATAGCAAGTCA
TTTGTTTCTTTTAAGCAATTTAAGCAGATGGAGAATAAGAAAAAATTAATGCATCAATCAAAGCCAAGCAGAACAAGTTT
GCAAAAATAG

Upstream 100 bases:

>100_bases
TATGACAAATGTCATATCATTTTATGACGTTTATGACTTATGAAAGGTTTAAATGAAGTCTAAAATAACAATAATAACAA
TTTGTTAGGGGAGGAAAAGG

Downstream 100 bases:

>100_bases
CAGAATCATTATTATAGATGAATCAATTTTTTAAAATAATGTAGTTATTAATGTTCAGATTACAAGAAATTCTTGGCTTT
GATTGTAATGGAAGACGGCG

Product: fatty-acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSKQKQAQLRKSVSAFAKSDKRTSIIQLINSILPFFLLWFLAYQSLSISIWLSLGVSVIAAGFVVRIFIIFHDCTHMSFF
KNAKANRIVGTITGIITHFAFEKWKRDHAIHHATSSNLDKRGTGDVWVMTVDEYTEASFWGRLSYRLYRNPIIMFGLGPA
YLFLISNRFNRKGAKRKERWNTYLINFSIVAIYGLLIWAIGWQAFLIVQLPILFIAGAAGIWLFYVQHQFEDSYFENEDE
WDYVKAAVDGSSYYKLPKAIEWITGSIGYHHVHHLSPRVPNYHLEKAHESTPPLHKATTITLLTSLQSLRFRLYDENSKS
FVSFKQFKQMENKKKLMHQSKPSRTSLQK

Sequences:

>Translated_349_residues
MSKQKQAQLRKSVSAFAKSDKRTSIIQLINSILPFFLLWFLAYQSLSISIWLSLGVSVIAAGFVVRIFIIFHDCTHMSFF
KNAKANRIVGTITGIITHFAFEKWKRDHAIHHATSSNLDKRGTGDVWVMTVDEYTEASFWGRLSYRLYRNPIIMFGLGPA
YLFLISNRFNRKGAKRKERWNTYLINFSIVAIYGLLIWAIGWQAFLIVQLPILFIAGAAGIWLFYVQHQFEDSYFENEDE
WDYVKAAVDGSSYYKLPKAIEWITGSIGYHHVHHLSPRVPNYHLEKAHESTPPLHKATTITLLTSLQSLRFRLYDENSKS
FVSFKQFKQMENKKKLMHQSKPSRTSLQK
>Mature_348_residues
SKQKQAQLRKSVSAFAKSDKRTSIIQLINSILPFFLLWFLAYQSLSISIWLSLGVSVIAAGFVVRIFIIFHDCTHMSFFK
NAKANRIVGTITGIITHFAFEKWKRDHAIHHATSSNLDKRGTGDVWVMTVDEYTEASFWGRLSYRLYRNPIIMFGLGPAY
LFLISNRFNRKGAKRKERWNTYLINFSIVAIYGLLIWAIGWQAFLIVQLPILFIAGAAGIWLFYVQHQFEDSYFENEDEW
DYVKAAVDGSSYYKLPKAIEWITGSIGYHHVHHLSPRVPNYHLEKAHESTPPLHKATTITLLTSLQSLRFRLYDENSKSF
VSFKQFKQMENKKKLMHQSKPSRTSLQK

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 40501; Mature: 40370

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQKQAQLRKSVSAFAKSDKRTSIIQLINSILPFFLLWFLAYQSLSISIWLSLGVSVIA
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFVVRIFIIFHDCTHMSFFKNAKANRIVGTITGIITHFAFEKWKRDHAIHHATSSNLDK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGTGDVWVMTVDEYTEASFWGRLSYRLYRNPIIMFGLGPAYLFLISNRFNRKGAKRKERW
CCCCCEEEEEECCHHCHHHHHHHHHEEECCCEEEEECCHHHHHHHHCHHCCCCCHHHHHC
NTYLINFSIVAIYGLLIWAIGWQAFLIVQLPILFIAGAAGIWLFYVQHQFEDSYFENEDE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDYVKAAVDGSSYYKLPKAIEWITGSIGYHHVHHLSPRVPNYHLEKAHESTPPLHKATTI
HHHHHHEECCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHH
TLLTSLQSLRFRLYDENSKSFVSFKQFKQMENKKKLMHQSKPSRTSLQK
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SKQKQAQLRKSVSAFAKSDKRTSIIQLINSILPFFLLWFLAYQSLSISIWLSLGVSVIA
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFVVRIFIIFHDCTHMSFFKNAKANRIVGTITGIITHFAFEKWKRDHAIHHATSSNLDK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGTGDVWVMTVDEYTEASFWGRLSYRLYRNPIIMFGLGPAYLFLISNRFNRKGAKRKERW
CCCCCEEEEEECCHHCHHHHHHHHHEEECCCEEEEECCHHHHHHHHCHHCCCCCHHHHHC
NTYLINFSIVAIYGLLIWAIGWQAFLIVQLPILFIAGAAGIWLFYVQHQFEDSYFENEDE
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
WDYVKAAVDGSSYYKLPKAIEWITGSIGYHHVHHLSPRVPNYHLEKAHESTPPLHKATTI
HHHHHHEECCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHH
TLLTSLQSLRFRLYDENSKSFVSFKQFKQMENKKKLMHQSKPSRTSLQK
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]