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The map label for this gene is dapA [H]

Identifier: 23100300

GI number: 23100300

Start: 2928827

End: 2929741

Strand: Reverse

Name: dapA [H]

Synonym: OB2845

Alternate gene names: 23100300

Gene position: 2929741-2928827 (Counterclockwise)

Preceding gene: 23100301

Following gene: 23100299

Centisome position: 80.7

GC content: 38.58

Gene sequence:

>915_bases
ATGGATTACGGGGAATTTAGTAAACGATTTTCAACGATTTCGGGGATTAATATTGTTCCTTTTTTAGAAGGTACGAGAGA
AATTGACTGGAAAGGGTTGGATGATAATGTCGAGTTCCTTCTCCAAAATGGAATAGAGGTTATTGTTCCAAATGGAAATA
CTGGTGAATTTTATGCACTGACCATAGAGGAGGCAAAGCAGGTAGCAACTAGAGTAACAGAATTAGTAAACGGTCGAGCA
ACGGTTGTGGCGGGTATTGGTTATTCTGTAGATACCGCTATAGAATTAGGGAAATCTGCAATCGATTCGGGAGCAGATTG
TGTGATGATTCATCAACCAGTTCATCCCTATATTACCGATGCTGGGGCGGTAGAATACTATAGAAATATTATTGAGGCAT
TAGATGCTCCATCGATCATTTACTTTAAAGATGCTCACTTGAGTGATGATGTGATTAAAGAATTAGCACCTTTAGATAAA
TTGGTTGGAATCAAATATGCAATTAACGATATTCAACGTGTAACCCAAGTAATTCGTGCTGTACCGAAATCTAGTAATGT
TGCATTTATTTGTGGGACAGCGGAGAAATGGGCACCATTTTTCTATCATGCTGGGGCAGTAGGTTTTACTTCAGGATTGG
TCAATGTTTTTCCACAGAAATCCTTTGCGTTACTGGAAGCATTAGAAGAAGGCAATCAAGAAAAGATATGGGACGTTTGG
GAAGATGTTGTTCCATTTGAAGATCTAAGAGCCAAACATAATAATGGCAATAACGTTGTAATAATTAAAGAGGCCATGGA
ACAATTAGGTTTAAGAGCTGGAGTTACTAGGGAACCGGTAAATCCTTTATCACCAAATGATAGACTAGAGTTAGAGGAGC
TATTAAAAAGCTGGAATACGCAAGAGGTGAGGTGA

Upstream 100 bases:

>100_bases
AGAACACTATTTATCTCAAAACAAGCAGCGTAATTAGATAAAGCGTTTATTAGATAGTTTCCTGGCAAAATAATTTAAAA
GATAAAGGAGAGAAGCGAAC

Downstream 100 bases:

>100_bases
CAGCGAATGGTATTTCGAGTATTAGTCCCGCAAAAGATTGCACAAGAAGGAATTAGATTACTAGAGGAAAACGGTGCTAG
TATTGTTGTTCCACCTAGCC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDYGEFSKRFSTISGINIVPFLEGTREIDWKGLDDNVEFLLQNGIEVIVPNGNTGEFYALTIEEAKQVATRVTELVNGRA
TVVAGIGYSVDTAIELGKSAIDSGADCVMIHQPVHPYITDAGAVEYYRNIIEALDAPSIIYFKDAHLSDDVIKELAPLDK
LVGIKYAINDIQRVTQVIRAVPKSSNVAFICGTAEKWAPFFYHAGAVGFTSGLVNVFPQKSFALLEALEEGNQEKIWDVW
EDVVPFEDLRAKHNNGNNVVIIKEAMEQLGLRAGVTREPVNPLSPNDRLELEELLKSWNTQEVR

Sequences:

>Translated_304_residues
MDYGEFSKRFSTISGINIVPFLEGTREIDWKGLDDNVEFLLQNGIEVIVPNGNTGEFYALTIEEAKQVATRVTELVNGRA
TVVAGIGYSVDTAIELGKSAIDSGADCVMIHQPVHPYITDAGAVEYYRNIIEALDAPSIIYFKDAHLSDDVIKELAPLDK
LVGIKYAINDIQRVTQVIRAVPKSSNVAFICGTAEKWAPFFYHAGAVGFTSGLVNVFPQKSFALLEALEEGNQEKIWDVW
EDVVPFEDLRAKHNNGNNVVIIKEAMEQLGLRAGVTREPVNPLSPNDRLELEELLKSWNTQEVR
>Mature_304_residues
MDYGEFSKRFSTISGINIVPFLEGTREIDWKGLDDNVEFLLQNGIEVIVPNGNTGEFYALTIEEAKQVATRVTELVNGRA
TVVAGIGYSVDTAIELGKSAIDSGADCVMIHQPVHPYITDAGAVEYYRNIIEALDAPSIIYFKDAHLSDDVIKELAPLDK
LVGIKYAINDIQRVTQVIRAVPKSSNVAFICGTAEKWAPFFYHAGAVGFTSGLVNVFPQKSFALLEALEEGNQEKIWDVW
EDVVPFEDLRAKHNNGNNVVIIKEAMEQLGLRAGVTREPVNPLSPNDRLELEELLKSWNTQEVR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=291, Percent_Identity=25.4295532646048, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788823, Length=269, Percent_Identity=26.3940520446097, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082415, Length=276, Percent_Identity=25, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786463, Length=269, Percent_Identity=25.2788104089219, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789620, Length=283, Percent_Identity=24.0282685512367, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33698; Mature: 33698

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYGEFSKRFSTISGINIVPFLEGTREIDWKGLDDNVEFLLQNGIEVIVPNGNTGEFYAL
CCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEE
TIEEAKQVATRVTELVNGRATVVAGIGYSVDTAIELGKSAIDSGADCVMIHQPVHPYITD
EHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
AGAVEYYRNIIEALDAPSIIYFKDAHLSDDVIKELAPLDKLVGIKYAINDIQRVTQVIRA
CHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKSSNVAFICGTAEKWAPFFYHAGAVGFTSGLVNVFPQKSFALLEALEEGNQEKIWDVW
CCCCCCEEEEECCHHHHCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
EDVVPFEDLRAKHNNGNNVVIIKEAMEQLGLRAGVTREPVNPLSPNDRLELEELLKSWNT
HHCCCHHHHHHHCCCCCEEEEEHHHHHHCCHHCCCCCCCCCCCCCCCCCHHHHHHHCCCC
QEVR
CCCC
>Mature Secondary Structure
MDYGEFSKRFSTISGINIVPFLEGTREIDWKGLDDNVEFLLQNGIEVIVPNGNTGEFYAL
CCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEE
TIEEAKQVATRVTELVNGRATVVAGIGYSVDTAIELGKSAIDSGADCVMIHQPVHPYITD
EHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
AGAVEYYRNIIEALDAPSIIYFKDAHLSDDVIKELAPLDKLVGIKYAINDIQRVTQVIRA
CHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKSSNVAFICGTAEKWAPFFYHAGAVGFTSGLVNVFPQKSFALLEALEEGNQEKIWDVW
CCCCCCEEEEECCHHHHCHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHH
EDVVPFEDLRAKHNNGNNVVIIKEAMEQLGLRAGVTREPVNPLSPNDRLELEELLKSWNT
HHCCCHHHHHHHCCCCCEEEEEHHHHHHCCHHCCCCCCCCCCCCCCCCCHHHHHHHCCCC
QEVR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA