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The map label for this gene is kdgR [H]

Identifier: 23100275

GI number: 23100275

Start: 2899683

End: 2900456

Strand: Direct

Name: kdgR [H]

Synonym: OB2820

Alternate gene names: 23100275

Gene position: 2899683-2900456 (Clockwise)

Preceding gene: 23100264

Following gene: 28563947

Centisome position: 79.87

GC content: 32.69

Gene sequence:

>774_bases
ATGTCAAACGTTCAATCTATTGAACGTGCTTTTACAATTTTAAAGGTACTTTCAAATAATCCCGATGGTTTGAGAATAAC
TGTTTTGGCTGAAAATTCTAGCTTAACCAAAAGTACAACGCATCGAATTACTTCAACACTCGTAAATTTAGGTTATGTCC
AACAAGACCCTGAAACTGAAAAATATATGCTTGGGAATCAATTAATAAAATTAACAAGTGTAATGTTAAACAACATGGAT
GTAATTAAAGTTGCAGAACCCTACCTTGTTAATTTATCCAGAGATGTTAATGAAACAGTTCATTTATGTGTAGAAAGTAA
TGGAGAGGTACTTTATGTAGATAAAAAAGAAAAGAATCAAAACATCAGAATGTATTCTACAATCGGTAGTCGTGCCCCGC
TCTATTGTACTGCTGTTGGTAAAGTTCTACTTTCCGGTATGAATCCAGTTTATTTTGAGGAAGTTATTAATAACATGACA
TTTGAATTAAGAACAGCGCTAACCATCACCTCACAAGTGAAGCTTAGAAAAGAAATAGAGAAGGTAAAATTACAAGGATA
TGCATTAGACAATGTGGAGAATGAAGAAGGAATTCGCTGCATCGCCTCCCCTATCTACGATTACAAGGGGAATATAATCG
CAAGTTTTAGTATTTCGGGTCCAACTAATAGGGTATCTATTGATAGAGTTAATCTTGAATTAGTAGATAAAGTAAATATG
ACTTCCAAGTTAATTTCTGAGCAATTTGGATACATAAAAAAAGAAAGTATTTAA

Upstream 100 bases:

>100_bases
GTGAATATTTAACTTACAAATAAAAACTCAATTTACAAAAGATAATTTATCCTCTACTATTAAATGGAAGCGATATCTTT
AAGAAAAGGGTGAGAACAAT

Downstream 100 bases:

>100_bases
TTTCATATTGAATTGCACTTTTTTCTTATGTCATGAAAACCAAAAAGGAAGCCTGCTACAGCTTCCTTTTTTATATTGGT
CTAGGAAATTATAAAATTTT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSNVQSIERAFTILKVLSNNPDGLRITVLAENSSLTKSTTHRITSTLVNLGYVQQDPETEKYMLGNQLIKLTSVMLNNMD
VIKVAEPYLVNLSRDVNETVHLCVESNGEVLYVDKKEKNQNIRMYSTIGSRAPLYCTAVGKVLLSGMNPVYFEEVINNMT
FELRTALTITSQVKLRKEIEKVKLQGYALDNVENEEGIRCIASPIYDYKGNIIASFSISGPTNRVSIDRVNLELVDKVNM
TSKLISEQFGYIKKESI

Sequences:

>Translated_257_residues
MSNVQSIERAFTILKVLSNNPDGLRITVLAENSSLTKSTTHRITSTLVNLGYVQQDPETEKYMLGNQLIKLTSVMLNNMD
VIKVAEPYLVNLSRDVNETVHLCVESNGEVLYVDKKEKNQNIRMYSTIGSRAPLYCTAVGKVLLSGMNPVYFEEVINNMT
FELRTALTITSQVKLRKEIEKVKLQGYALDNVENEEGIRCIASPIYDYKGNIIASFSISGPTNRVSIDRVNLELVDKVNM
TSKLISEQFGYIKKESI
>Mature_256_residues
SNVQSIERAFTILKVLSNNPDGLRITVLAENSSLTKSTTHRITSTLVNLGYVQQDPETEKYMLGNQLIKLTSVMLNNMDV
IKVAEPYLVNLSRDVNETVHLCVESNGEVLYVDKKEKNQNIRMYSTIGSRAPLYCTAVGKVLLSGMNPVYFEEVINNMTF
ELRTALTITSQVKLRKEIEKVKLQGYALDNVENEEGIRCIASPIYDYKGNIIASFSISGPTNRVSIDRVNLELVDKVNMT
SKLISEQFGYIKKESI

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=249, Percent_Identity=39.3574297188755, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1786468, Length=251, Percent_Identity=32.6693227091633, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI87082359, Length=254, Percent_Identity=27.5590551181102, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1789999, Length=260, Percent_Identity=29.2307692307692, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786715, Length=227, Percent_Identity=29.9559471365639, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1788581, Length=251, Percent_Identity=26.2948207171315, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790752, Length=218, Percent_Identity=25.2293577981651, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28898; Mature: 28767

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVQSIERAFTILKVLSNNPDGLRITVLAENSSLTKSTTHRITSTLVNLGYVQQDPETE
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHH
KYMLGNQLIKLTSVMLNNMDVIKVAEPYLVNLSRDVNETVHLCVESNGEVLYVDKKEKNQ
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCC
NIRMYSTIGSRAPLYCTAVGKVLLSGMNPVYFEEVINNMTFELRTALTITSQVKLRKEIE
CEEEEEECCCCCCEEHHHHHHHHHHCCCHHHHHHHHCCCEEEEHEEEEHHHHHHHHHHHH
KVKLQGYALDNVENEEGIRCIASPIYDYKGNIIASFSISGPTNRVSIDRVNLELVDKVNM
HHHHCCEEECCCCCCCCCEEEECCHHCCCCCEEEEEEECCCCCEEEEEEECEEEHHHCCH
TSKLISEQFGYIKKESI
HHHHHHHHHCCEECCCC
>Mature Secondary Structure 
SNVQSIERAFTILKVLSNNPDGLRITVLAENSSLTKSTTHRITSTLVNLGYVQQDPETE
CCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHH
KYMLGNQLIKLTSVMLNNMDVIKVAEPYLVNLSRDVNETVHLCVESNGEVLYVDKKEKNQ
HHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCC
NIRMYSTIGSRAPLYCTAVGKVLLSGMNPVYFEEVINNMTFELRTALTITSQVKLRKEIE
CEEEEEECCCCCCEEHHHHHHHHHHCCCHHHHHHHHCCCEEEEHEEEEHHHHHHHHHHHH
KVKLQGYALDNVENEEGIRCIASPIYDYKGNIIASFSISGPTNRVSIDRVNLELVDKVNM
HHHHCCEEECCCCCCCCCEEEECCHHCCCCCEEEEEEECCCCCEEEEEEECEEEHHHCCH
TSKLISEQFGYIKKESI
HHHHHHHHHCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]