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The map label for this gene is gmuD [H]

Identifier: 23100218

GI number: 23100218

Start: 2833502

End: 2834899

Strand: Direct

Name: gmuD [H]

Synonym: OB2763

Alternate gene names: 23100218

Gene position: 2833502-2834899 (Clockwise)

Preceding gene: 23100217

Following gene: 23100219

Centisome position: 78.05

GC content: 35.91

Gene sequence:

>1398_bases
ATGACAGAACAAAACTATCAATTTCCTGCTGGATTCTGGTGGGGCAGTGCAACTTCTGCAACACAGATTGAAGGTGCAGC
AAATCAATATGGAAAAGGACAAAATATATGGGATCACTGGTATAACATACAACCTGAACGATTTTATAATCAAGTTGGTC
CAGAGCATACTTCTGACTTTTACCATCGCTATAAAGAAGACATTGCCTTAATGAAAGAATTCGGACATAATTCATTCCGT
CTTTCTATATCTTGGTCGAGGCTAATTCCAGATGGAGTAGGTGAAGTAAATGAAGAGGCTGTATCGTTCTATCATAATGT
TATTGATGAATTAATCGCCAATGATATCGAACCTTTTGTCAATCTGTTTCATTTTGATATGCCGCTCCCATTGCAAGAAA
TTGGTGGCTGGGAAAATCGTGAAGTTATAGAAATGTATCGTCAATATGCGAAAAAAGCATTCGAATTATTTGGAGATAAA
GTAAAAAAATGGTTTACATTTAACGAACCAATCGTACCAGTTGAAGGTGGATACCTATATAACTTCCATTACCCAAATGT
TGTAGATGCAAAAAGAGCAATACAAGTTGCTTACCATACCATTATAGCTCATGCAACTGCCGTTCAGACTTTTAAAGAAT
TGAATATTGAAAATGGAAAAATTGGTATTATCTTAAACTTAACACCATCTTATCCAAGAAGTGAAAACACAGCTGATCAA
AAAGCTGCGCATATCGCTGATCTATTCTTTAATCGCAGTTTCTTAGATCCTGCTGTACTAGGAGAGTACCCAGAAGATTT
AATTAACCTTTTAAAAGAACATAATCACCTTCCACAAACAGAGGATGGAGATGCAGGATTAATCAAGGAAAACACGATTG
ATATTTTAGGGGTGAATTACTATCAACCTAGAAGAGTAAAGGCAAAAGATAATTTGCCAAATCCGTACAGTCCTTTTATG
CCTGACTGGTTCTTTGATTCATATGAAATGCCAGGAAGACGCATGAATGAATATCGAGGATGGGAAATCTATGAAAAAGG
TGTCTATGATATTATGATTAATCTAAAAGAAAACTACCATAATATCGAATCATTTATTTCAGAAAATGGTATGGGTGTTC
AAGGCGAAGAACATTTTATCGAGAATGGACAAATTCAAGATGATTACCGAATCACCTTTATCAAAGATCACTTGAAATGG
CTACACCGAGCGATTGATGAGGGTTGTAATGCGAAAGGCTATCACCTTTGGACAACAATGGATAACTGGTCATGGTCAAA
CGCTTATAAAAATCGCTACGGATTCTTTTCTGTAAATATTGACACAATGGAACGAACTCCGAAGAAAAGTGCCTATTGGT
TTAAACAAATAAGTGAACAAAATGGATTTCACGCATAG

Upstream 100 bases:

>100_bases
CTTATTCATTCACAAGATCACTTAATGAATGCGATGACCATTAAAGACTTAGCAATCGAAATCATAGATATATACAGAAA
TAAGTAGTGGAGGTTTTACT

Downstream 100 bases:

>100_bases
ATATAGATAAAGAATAGATAGAAGGAGTTGTTTTTATGATAAAAAACAACTCCCTTCTCTACGTTAAGGAGGTGGATTAA
AATGGACACTAGATTACGTG

Product: beta-glucosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTEQNYQFPAGFWWGSATSATQIEGAANQYGKGQNIWDHWYNIQPERFYNQVGPEHTSDFYHRYKEDIALMKEFGHNSFR
LSISWSRLIPDGVGEVNEEAVSFYHNVIDELIANDIEPFVNLFHFDMPLPLQEIGGWENREVIEMYRQYAKKAFELFGDK
VKKWFTFNEPIVPVEGGYLYNFHYPNVVDAKRAIQVAYHTIIAHATAVQTFKELNIENGKIGIILNLTPSYPRSENTADQ
KAAHIADLFFNRSFLDPAVLGEYPEDLINLLKEHNHLPQTEDGDAGLIKENTIDILGVNYYQPRRVKAKDNLPNPYSPFM
PDWFFDSYEMPGRRMNEYRGWEIYEKGVYDIMINLKENYHNIESFISENGMGVQGEEHFIENGQIQDDYRITFIKDHLKW
LHRAIDEGCNAKGYHLWTTMDNWSWSNAYKNRYGFFSVNIDTMERTPKKSAYWFKQISEQNGFHA

Sequences:

>Translated_465_residues
MTEQNYQFPAGFWWGSATSATQIEGAANQYGKGQNIWDHWYNIQPERFYNQVGPEHTSDFYHRYKEDIALMKEFGHNSFR
LSISWSRLIPDGVGEVNEEAVSFYHNVIDELIANDIEPFVNLFHFDMPLPLQEIGGWENREVIEMYRQYAKKAFELFGDK
VKKWFTFNEPIVPVEGGYLYNFHYPNVVDAKRAIQVAYHTIIAHATAVQTFKELNIENGKIGIILNLTPSYPRSENTADQ
KAAHIADLFFNRSFLDPAVLGEYPEDLINLLKEHNHLPQTEDGDAGLIKENTIDILGVNYYQPRRVKAKDNLPNPYSPFM
PDWFFDSYEMPGRRMNEYRGWEIYEKGVYDIMINLKENYHNIESFISENGMGVQGEEHFIENGQIQDDYRITFIKDHLKW
LHRAIDEGCNAKGYHLWTTMDNWSWSNAYKNRYGFFSVNIDTMERTPKKSAYWFKQISEQNGFHA
>Mature_464_residues
TEQNYQFPAGFWWGSATSATQIEGAANQYGKGQNIWDHWYNIQPERFYNQVGPEHTSDFYHRYKEDIALMKEFGHNSFRL
SISWSRLIPDGVGEVNEEAVSFYHNVIDELIANDIEPFVNLFHFDMPLPLQEIGGWENREVIEMYRQYAKKAFELFGDKV
KKWFTFNEPIVPVEGGYLYNFHYPNVVDAKRAIQVAYHTIIAHATAVQTFKELNIENGKIGIILNLTPSYPRSENTADQK
AAHIADLFFNRSFLDPAVLGEYPEDLINLLKEHNHLPQTEDGDAGLIKENTIDILGVNYYQPRRVKAKDNLPNPYSPFMP
DWFFDSYEMPGRRMNEYRGWEIYEKGVYDIMINLKENYHNIESFISENGMGVQGEEHFIENGQIQDDYRITFIKDHLKWL
HRAIDEGCNAKGYHLWTTMDNWSWSNAYKNRYGFFSVNIDTMERTPKKSAYWFKQISEQNGFHA

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=483, Percent_Identity=31.6770186335404, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI32481206, Length=482, Percent_Identity=30.0829875518672, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI13273313, Length=485, Percent_Identity=31.1340206185567, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI28376633, Length=477, Percent_Identity=29.1404612159329, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI24497614, Length=481, Percent_Identity=28.4823284823285, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=41.8367346938776, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI2367174, Length=498, Percent_Identity=33.5341365461847, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789070, Length=485, Percent_Identity=34.639175257732, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI2367270, Length=484, Percent_Identity=31.8181818181818, Blast_Score=204, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17552856, Length=477, Percent_Identity=33.5429769392034, Blast_Score=238, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17539390, Length=469, Percent_Identity=33.6886993603412, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI21356577, Length=483, Percent_Identity=30.2277432712215, Blast_Score=230, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54531; Mature: 54400

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQNYQFPAGFWWGSATSATQIEGAANQYGKGQNIWDHWYNIQPERFYNQVGPEHTSDF
CCCCCCCCCCCEECCCCCCCHHCCCCHHHCCCCCCHHHHHCCCCHHHHHHHCCCCHHHHH
YHRYKEDIALMKEFGHNSFRLSISWSRLIPDGVGEVNEEAVSFYHNVIDELIANDIEPFV
HHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFHFDMPLPLQEIGGWENREVIEMYRQYAKKAFELFGDKVKKWFTFNEPIVPVEGGYLY
HHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEE
NFHYPNVVDAKRAIQVAYHTIIAHATAVQTFKELNIENGKIGIILNLTPSYPRSENTADQ
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHH
KAAHIADLFFNRSFLDPAVLGEYPEDLINLLKEHNHLPQTEDGDAGLIKENTIDILGVNY
HHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCEEEEECCC
YQPRRVKAKDNLPNPYSPFMPDWFFDSYEMPGRRMNEYRGWEIYEKGVYDIMINLKENYH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHCCEEEEEEECHHHHH
NIESFISENGMGVQGEEHFIENGQIQDDYRITFIKDHLKWLHRAIDEGCNAKGYHLWTTM
HHHHHHHCCCCCCCCCHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEC
DNWSWSNAYKNRYGFFSVNIDTMERTPKKSAYWFKQISEQNGFHA
CCCCCHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TEQNYQFPAGFWWGSATSATQIEGAANQYGKGQNIWDHWYNIQPERFYNQVGPEHTSDF
CCCCCCCCCCEECCCCCCCHHCCCCHHHCCCCCCHHHHHCCCCHHHHHHHCCCCHHHHH
YHRYKEDIALMKEFGHNSFRLSISWSRLIPDGVGEVNEEAVSFYHNVIDELIANDIEPFV
HHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFHFDMPLPLQEIGGWENREVIEMYRQYAKKAFELFGDKVKKWFTFNEPIVPVEGGYLY
HHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEE
NFHYPNVVDAKRAIQVAYHTIIAHATAVQTFKELNIENGKIGIILNLTPSYPRSENTADQ
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHH
KAAHIADLFFNRSFLDPAVLGEYPEDLINLLKEHNHLPQTEDGDAGLIKENTIDILGVNY
HHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCEEEEECCC
YQPRRVKAKDNLPNPYSPFMPDWFFDSYEMPGRRMNEYRGWEIYEKGVYDIMINLKENYH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHCCEEEEEEECHHHHH
NIESFISENGMGVQGEEHFIENGQIQDDYRITFIKDHLKWLHRAIDEGCNAKGYHLWTTM
HHHHHHHCCCCCCCCCHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEEC
DNWSWSNAYKNRYGFFSVNIDTMERTPKKSAYWFKQISEQNGFHA
CCCCCHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]