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The map label for this gene is endR [H]

Identifier: 23100160

GI number: 23100160

Start: 2774568

End: 2775569

Strand: Reverse

Name: endR [H]

Synonym: OB2705

Alternate gene names: 23100160

Gene position: 2775569-2774568 (Counterclockwise)

Preceding gene: 23100161

Following gene: 23100159

Centisome position: 76.45

GC content: 36.23

Gene sequence:

>1002_bases
ATGACAAAAAGAATCACAATCTCAGATGTTGCGATACATGCAGGCGTTTCAAAAAGCACAGTATCACAGTATTTGAACGG
ACGTTATGATTATATGGGACAGAAAACAAAAGAAAAAATTCAGTCCGCAATCAAAGAGTTAAAGTATAGTCCCAACATGG
TGGCCAGAAGTTTGAAACAAAAATCCTCGACTACCATTGGGGTTATTGTGGCAAATATTCTTCATGTATTTTCCACACAG
GTCATCCGAGCAATAGAAGATTTCTGCCATGAGAAAGGATTTCATGTCATTGTATGTAATGCAGACGACAATCCTGATAA
AGAGAAAACCTATATTGATATGCTTCGGGCAAAACAAGTAGACGGAATCATTGCTTTTCCAACCGGTGACAATGTTGCGC
TTTATCAAGGTCTTTTAGAGGAACAATATCCACTCGTATTTATGGATAGATTGGTAGATGGATTAGATATACCTACTGTA
TTACTCGATAACGATAAAGCTGCAACACTAGCAGTCGATTTACTAAAAGATTATCAACGACCAGCCATCGTAACTCCACC
TTTAAAAGAAAATTTGACACCAAGAATGGAAAGATTAATTGGTTTTAAAAATGAACTAGCTAAACATGGGGTATCATTGC
CTGATGAATATATTGCTTGTGGTGAAATTAGTGAAATTCAAAAAAAGCTGACGGAGCTTTTTCAGTTAACTAAAGCCCCT
GATGCCATTTTTGCGATAAATGATCGAGTTTTACACGAAGTATTAACATTTATGAATCATCAACATATCCGAATTCCAGA
AGATGTAGCATTAGTAAATGTTGATGATGTCTCGTTTGCAGAATTTTATCAGCCAGCATTAACAACAATTTCACAGCCAG
CTTTTGAAATGGGAAAGAAAGCAGCTGAACTATTATTTACACAAATCAAAAATCCACAAGATAGAAGTACAATGGAAACC
TTCCGTTTCGAACCAATGGTGAATCGGAGAAAATCGTGTTGA

Upstream 100 bases:

>100_bases
CATCCAAAAATTAGTATTGTAAAACGGTTACATTTATTTTATACTGTTACTAAATCGATTTACTAAACCGTTTTAGTTAT
AGAGATAGAAGGGGTATATT

Downstream 100 bases:

>100_bases
ACAGAAAGGAAAGATAAGGATGATGAAACAAAAAGTAAATACTATCGCTAAAGAAATTCAGGAAGTACTTGGACAAGTTA
ATGAAGCTGAACTAATTGAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTKRITISDVAIHAGVSKSTVSQYLNGRYDYMGQKTKEKIQSAIKELKYSPNMVARSLKQKSSTTIGVIVANILHVFSTQ
VIRAIEDFCHEKGFHVIVCNADDNPDKEKTYIDMLRAKQVDGIIAFPTGDNVALYQGLLEEQYPLVFMDRLVDGLDIPTV
LLDNDKAATLAVDLLKDYQRPAIVTPPLKENLTPRMERLIGFKNELAKHGVSLPDEYIACGEISEIQKKLTELFQLTKAP
DAIFAINDRVLHEVLTFMNHQHIRIPEDVALVNVDDVSFAEFYQPALTTISQPAFEMGKKAAELLFTQIKNPQDRSTMET
FRFEPMVNRRKSC

Sequences:

>Translated_333_residues
MTKRITISDVAIHAGVSKSTVSQYLNGRYDYMGQKTKEKIQSAIKELKYSPNMVARSLKQKSSTTIGVIVANILHVFSTQ
VIRAIEDFCHEKGFHVIVCNADDNPDKEKTYIDMLRAKQVDGIIAFPTGDNVALYQGLLEEQYPLVFMDRLVDGLDIPTV
LLDNDKAATLAVDLLKDYQRPAIVTPPLKENLTPRMERLIGFKNELAKHGVSLPDEYIACGEISEIQKKLTELFQLTKAP
DAIFAINDRVLHEVLTFMNHQHIRIPEDVALVNVDDVSFAEFYQPALTTISQPAFEMGKKAAELLFTQIKNPQDRSTMET
FRFEPMVNRRKSC
>Mature_332_residues
TKRITISDVAIHAGVSKSTVSQYLNGRYDYMGQKTKEKIQSAIKELKYSPNMVARSLKQKSSTTIGVIVANILHVFSTQV
IRAIEDFCHEKGFHVIVCNADDNPDKEKTYIDMLRAKQVDGIIAFPTGDNVALYQGLLEEQYPLVFMDRLVDGLDIPTVL
LDNDKAATLAVDLLKDYQRPAIVTPPLKENLTPRMERLIGFKNELAKHGVSLPDEYIACGEISEIQKKLTELFQLTKAPD
AIFAINDRVLHEVLTFMNHQHIRIPEDVALVNVDDVSFAEFYQPALTTISQPAFEMGKKAAELLFTQIKNPQDRSTMETF
RFEPMVNRRKSC

Specific function: Putative repressor of the endoglucanase operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=31.629392971246, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790194, Length=340, Percent_Identity=31.1764705882353, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=29.7297297297297, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789068, Length=299, Percent_Identity=27.4247491638796, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788474, Length=333, Percent_Identity=27.3273273273273, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789202, Length=330, Percent_Identity=27.2727272727273, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=28.4829721362229, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786540, Length=309, Percent_Identity=27.1844660194175, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786268, Length=313, Percent_Identity=23.3226837060703, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=24.4372990353698, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787906, Length=334, Percent_Identity=26.9461077844311, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790689, Length=319, Percent_Identity=23.1974921630094, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=23.8993710691824, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37637; Mature: 37506

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRITISDVAIHAGVSKSTVSQYLNGRYDYMGQKTKEKIQSAIKELKYSPNMVARSLKQ
CCCEEEEHHHHHHCCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
KSSTTIGVIVANILHVFSTQVIRAIEDFCHEKGFHVIVCNADDNPDKEKTYIDMLRAKQV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
DGIIAFPTGDNVALYQGLLEEQYPLVFMDRLVDGLDIPTVLLDNDKAATLAVDLLKDYQR
CCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCC
PAIVTPPLKENLTPRMERLIGFKNELAKHGVSLPDEYIACGEISEIQKKLTELFQLTKAP
CCEECCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCC
DAIFAINDRVLHEVLTFMNHQHIRIPEDVALVNVDDVSFAEFYQPALTTISQPAFEMGKK
CCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHH
AAELLFTQIKNPQDRSTMETFRFEPMVNRRKSC
HHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure 
TKRITISDVAIHAGVSKSTVSQYLNGRYDYMGQKTKEKIQSAIKELKYSPNMVARSLKQ
CCEEEEHHHHHHCCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
KSSTTIGVIVANILHVFSTQVIRAIEDFCHEKGFHVIVCNADDNPDKEKTYIDMLRAKQV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
DGIIAFPTGDNVALYQGLLEEQYPLVFMDRLVDGLDIPTVLLDNDKAATLAVDLLKDYQR
CCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCC
PAIVTPPLKENLTPRMERLIGFKNELAKHGVSLPDEYIACGEISEIQKKLTELFQLTKAP
CCEECCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCC
DAIFAINDRVLHEVLTFMNHQHIRIPEDVALVNVDDVSFAEFYQPALTTISQPAFEMGKK
CCEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHH
AAELLFTQIKNPQDRSTMETFRFEPMVNRRKSC
HHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2307659; 1639817 [H]