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The map label for this gene is katB [H]

Identifier: 23100114

GI number: 23100114

Start: 2726078

End: 2728141

Strand: Direct

Name: katB [H]

Synonym: OB2659

Alternate gene names: 23100114

Gene position: 2726078-2728141 (Clockwise)

Preceding gene: 23100113

Following gene: 23100115

Centisome position: 75.09

GC content: 37.84

Gene sequence:

>2064_bases
ATGTCAGATCAAGATAATCAACAAGAAAAACGAAAACAAGATGACAATAAGAAAATCGATCAATTAAAGAAATTCTATCG
GGATAATACTGACAAGATAATGACTACAGATGAAGGGGTAAAGATATCCAATGATGAGAATACGTTAAGTGCAGGAGACA
GAGGTCCTCAATTATTAGAAGATTTTATGTATCGTGAAAAACTGGCTCACTTCGATCGAGAACGTATCCCTGAACGAAAC
GTTCACGCACGGGGCTATGGTGCACATGGAGTATTTGAATGTTATGAATCTCAATCAGATTTAACGAAGGCACATTTCTT
ACAAAAAGCTGGGCAACAAACACCTGTATTTGTCCGATTCTCACAAGTAGCCGGTTCAAAAGGAGCCAATGAAACACTAC
GTGACGTTCGGGGTTTTGCTACAAAATTTTATACGAATGAGGGAAATTTTGATTTAGTTGGAAATAATATTCCTATATTT
TTCATTCAAGATGGTATTAAGTTTCCAGACTTAATTCACGCACTGAAACCTGAACCGAACAATGAAATCCCTCAAGGACA
AACAGCGCATGATACATTCTGGGATTTTATCGGTAGTAATGAAGAATCGGCAGCTATGATGATGTGGATTATGTCAGATC
GGACCATCCCTAGAAGTTTCCGTACTATACAAGGATTCGGAGTACATACATTTCGGCTTGTTAATGCGGAAGGTAAATCC
GTCTTTTGTAAATTTCATTGGCGGCCTGTTCTAGGGATACATTCATTAATTTGGAATGAAGCGCAAAAAATTGGCGGTGC
TGATCCTGACTTTCACCGAAGAGACCTTTGGGAAAATATTGAACAAGGATTTTATCCAGAATATGAGCTAGGAGTTCAGG
TCATCGAGGAAGGGCAAGAATTTGATTTTGATTTCGATATACTAGATGCAACAAAGCTCTGGCCAGAAGAAGAAGTACCA
TTACAAATGATTGGAAAAATGACTTTAAATAAAAACGTAGAGAATGTTTTTGCTGAGACTGAACAAGTCGCACTACACCC
AGGCAACATTGTACCAGGTATTGATTTCACGAATGATCCTCTACTACAAGGAAGGCTATTCTCCTATACGGATACGCAAA
TTTATCGAGTTGGTACTAACTTCAAACAACTTCCTATTAATCGTCCCGTATGCCCTTTTCACAATAATCATCGCGATGGA
TCTCAACGTTATATTATTGATAAGGGCCAAGTAGCCTACCATCAGAATTATTTAGCTGGTAATACTCCATACACCGTACC
TGGTTCTCAAGGTGGTTTTGTTACGTACCCATCTTTAGTAGAAGGATTAAAAGTACGAAAAACTGCGCCTAGTTTTCTCG
ATCACTTCTCACAAGCAAGACTATTTTGGAACAGTATGACAGATGTTGAACAAAGTCATATACTTCAAGCATTTAGTTTT
GAATTAGGTAAAGTTAATGTTCCAGAGGTACGCCAACGTGTTGTAAATCTTATCGGTCATATAAGCCGACCGCTCGCTAC
TGCAGTAGCAGAACAAGTTGGTGTGGAACCACCAGATAAGAGCATAAAACAATCAGATGTCACTAAATCCTCCCCTACTT
TAAGTTTAATGAATACAAAATTCCTTCCTAATACATTAAAAGTTGCTATTATTGTTGGTAATGGATATGGTGGCAACGCT
TTAGAATCATTATTAGAATCTTTAAAGGAAGTCGAACTTAAACCATATATAATAAGCGAGCGCTTAGGAGAAATAACTGC
AGATAATGGTGATACCTTAAATGTAGATGCTACCTTCTTAACAACTTCACCAGTTCTGTACGATGGGTTACTTGTTGTTG
GTGGAGATCATATCAATGATCAGTTTGCTTATGAAGCTGGCAACTTTATTACTGAGCAATTTAACCATTATAAACCAATT
GGAGGCATGGAAGAAGGTGCTACTTTAATTCAACAGTTAGGAATTGCTAATCGACCAGGAGTGTTCATAAGTCAATCAGG
CAGCAGACAATTCACTAGACAATTTATAGACGGAATGGCAAAACAACGATTTTGGGATAGATAA

Upstream 100 bases:

>100_bases
AGATTTTTCTTACTTAGAAGTCATCTCTTAACTCTGTTATGAATACACTCTTAATGATGTTTTGCATAATCTCTAAGCTT
TATTAGGAGGGGTAATAAAT

Downstream 100 bases:

>100_bases
ATAAGATTAGAATGCTACCACAGTAATTCATGCTGTGGTTTTTTTGTGTTTAAGATGATCCAAAGCATGTAAAATGTCCG
TTATCTATTTAAACATTTTA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MSDQDNQQEKRKQDDNKKIDQLKKFYRDNTDKIMTTDEGVKISNDENTLSAGDRGPQLLEDFMYREKLAHFDRERIPERN
VHARGYGAHGVFECYESQSDLTKAHFLQKAGQQTPVFVRFSQVAGSKGANETLRDVRGFATKFYTNEGNFDLVGNNIPIF
FIQDGIKFPDLIHALKPEPNNEIPQGQTAHDTFWDFIGSNEESAAMMMWIMSDRTIPRSFRTIQGFGVHTFRLVNAEGKS
VFCKFHWRPVLGIHSLIWNEAQKIGGADPDFHRRDLWENIEQGFYPEYELGVQVIEEGQEFDFDFDILDATKLWPEEEVP
LQMIGKMTLNKNVENVFAETEQVALHPGNIVPGIDFTNDPLLQGRLFSYTDTQIYRVGTNFKQLPINRPVCPFHNNHRDG
SQRYIIDKGQVAYHQNYLAGNTPYTVPGSQGGFVTYPSLVEGLKVRKTAPSFLDHFSQARLFWNSMTDVEQSHILQAFSF
ELGKVNVPEVRQRVVNLIGHISRPLATAVAEQVGVEPPDKSIKQSDVTKSSPTLSLMNTKFLPNTLKVAIIVGNGYGGNA
LESLLESLKEVELKPYIISERLGEITADNGDTLNVDATFLTTSPVLYDGLLVVGGDHINDQFAYEAGNFITEQFNHYKPI
GGMEEGATLIQQLGIANRPGVFISQSGSRQFTRQFIDGMAKQRFWDR

Sequences:

>Translated_687_residues
MSDQDNQQEKRKQDDNKKIDQLKKFYRDNTDKIMTTDEGVKISNDENTLSAGDRGPQLLEDFMYREKLAHFDRERIPERN
VHARGYGAHGVFECYESQSDLTKAHFLQKAGQQTPVFVRFSQVAGSKGANETLRDVRGFATKFYTNEGNFDLVGNNIPIF
FIQDGIKFPDLIHALKPEPNNEIPQGQTAHDTFWDFIGSNEESAAMMMWIMSDRTIPRSFRTIQGFGVHTFRLVNAEGKS
VFCKFHWRPVLGIHSLIWNEAQKIGGADPDFHRRDLWENIEQGFYPEYELGVQVIEEGQEFDFDFDILDATKLWPEEEVP
LQMIGKMTLNKNVENVFAETEQVALHPGNIVPGIDFTNDPLLQGRLFSYTDTQIYRVGTNFKQLPINRPVCPFHNNHRDG
SQRYIIDKGQVAYHQNYLAGNTPYTVPGSQGGFVTYPSLVEGLKVRKTAPSFLDHFSQARLFWNSMTDVEQSHILQAFSF
ELGKVNVPEVRQRVVNLIGHISRPLATAVAEQVGVEPPDKSIKQSDVTKSSPTLSLMNTKFLPNTLKVAIIVGNGYGGNA
LESLLESLKEVELKPYIISERLGEITADNGDTLNVDATFLTTSPVLYDGLLVVGGDHINDQFAYEAGNFITEQFNHYKPI
GGMEEGATLIQQLGIANRPGVFISQSGSRQFTRQFIDGMAKQRFWDR
>Mature_686_residues
SDQDNQQEKRKQDDNKKIDQLKKFYRDNTDKIMTTDEGVKISNDENTLSAGDRGPQLLEDFMYREKLAHFDRERIPERNV
HARGYGAHGVFECYESQSDLTKAHFLQKAGQQTPVFVRFSQVAGSKGANETLRDVRGFATKFYTNEGNFDLVGNNIPIFF
IQDGIKFPDLIHALKPEPNNEIPQGQTAHDTFWDFIGSNEESAAMMMWIMSDRTIPRSFRTIQGFGVHTFRLVNAEGKSV
FCKFHWRPVLGIHSLIWNEAQKIGGADPDFHRRDLWENIEQGFYPEYELGVQVIEEGQEFDFDFDILDATKLWPEEEVPL
QMIGKMTLNKNVENVFAETEQVALHPGNIVPGIDFTNDPLLQGRLFSYTDTQIYRVGTNFKQLPINRPVCPFHNNHRDGS
QRYIIDKGQVAYHQNYLAGNTPYTVPGSQGGFVTYPSLVEGLKVRKTAPSFLDHFSQARLFWNSMTDVEQSHILQAFSFE
LGKVNVPEVRQRVVNLIGHISRPLATAVAEQVGVEPPDKSIKQSDVTKSSPTLSLMNTKFLPNTLKVAIIVGNGYGGNAL
ESLLESLKEVELKPYIISERLGEITADNGDTLNVDATFLTTSPVLYDGLLVVGGDHINDQFAYEAGNFITEQFNHYKPIG
GMEEGATLIQQLGIANRPGVFISQSGSRQFTRQFIDGMAKQRFWDR

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=452, Percent_Identity=40.7079646017699, Blast_Score=341, Evalue=1e-93,
Organism=Escherichia coli, GI48994891, Length=686, Percent_Identity=50.7288629737609, Blast_Score=684, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25151141, Length=506, Percent_Identity=40.9090909090909, Blast_Score=377, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI25147792, Length=510, Percent_Identity=40.1960784313725, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71998444, Length=478, Percent_Identity=40.7949790794979, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320462, Length=491, Percent_Identity=35.8452138492872, Blast_Score=312, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6321525, Length=343, Percent_Identity=42.5655976676385, Blast_Score=289, Evalue=8e-79,
Organism=Drosophila melanogaster, GI17981717, Length=440, Percent_Identity=39.0909090909091, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI19920968, Length=466, Percent_Identity=35.8369098712446, Blast_Score=314, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 77757; Mature: 77626

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQDNQQEKRKQDDNKKIDQLKKFYRDNTDKIMTTDEGVKISNDENTLSAGDRGPQLLE
CCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCCCCCHHHHH
DFMYREKLAHFDRERIPERNVHARGYGAHGVFECYESQSDLTKAHFLQKAGQQTPVFVRF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEE
SQVAGSKGANETLRDVRGFATKFYTNEGNFDLVGNNIPIFFIQDGIKFPDLIHALKPEPN
HHHCCCCCCHHHHHHHHHHHHHEEECCCCEEEECCCCEEEEEECCCCCHHHHHHHCCCCC
NEIPQGQTAHDTFWDFIGSNEESAAMMMWIMSDRTIPRSFRTIQGFGVHTFRLVNAEGKS
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEEEECCCCE
VFCKFHWRPVLGIHSLIWNEAQKIGGADPDFHRRDLWENIEQGFYPEYELGVQVIEEGQE
EEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
FDFDFDILDATKLWPEEEVPLQMIGKMTLNKNVENVFAETEQVALHPGNIVPGIDFTNDP
CCCCEEEECHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCC
LLQGRLFSYTDTQIYRVGTNFKQLPINRPVCPFHNNHRDGSQRYIIDKGQVAYHQNYLAG
CCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCEECC
NTPYTVPGSQGGFVTYPSLVEGLKVRKTAPSFLDHFSQARLFWNSMTDVEQSHILQAFSF
CCCEECCCCCCCEEECHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGKVNVPEVRQRVVNLIGHISRPLATAVAEQVGVEPPDKSIKQSDVTKSSPTLSLMNTK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEEEECC
FLPNTLKVAIIVGNGYGGNALESLLESLKEVELKPYIISERLGEITADNGDTLNVDATFL
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCEEEEEEEEE
TTSPVLYDGLLVVGGDHINDQFAYEAGNFITEQFNHYKPIGGMEEGATLIQQLGIANRPG
ECCCHHHCCEEEECCCCCCCHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
VFISQSGSRQFTRQFIDGMAKQRFWDR
EEEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDQDNQQEKRKQDDNKKIDQLKKFYRDNTDKIMTTDEGVKISNDENTLSAGDRGPQLLE
CCCCCHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCCCCCHHHHH
DFMYREKLAHFDRERIPERNVHARGYGAHGVFECYESQSDLTKAHFLQKAGQQTPVFVRF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEE
SQVAGSKGANETLRDVRGFATKFYTNEGNFDLVGNNIPIFFIQDGIKFPDLIHALKPEPN
HHHCCCCCCHHHHHHHHHHHHHEEECCCCEEEECCCCEEEEEECCCCCHHHHHHHCCCCC
NEIPQGQTAHDTFWDFIGSNEESAAMMMWIMSDRTIPRSFRTIQGFGVHTFRLVNAEGKS
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEEEECCCCE
VFCKFHWRPVLGIHSLIWNEAQKIGGADPDFHRRDLWENIEQGFYPEYELGVQVIEEGQE
EEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
FDFDFDILDATKLWPEEEVPLQMIGKMTLNKNVENVFAETEQVALHPGNIVPGIDFTNDP
CCCCEEEECHHHCCCCCCCCHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCC
LLQGRLFSYTDTQIYRVGTNFKQLPINRPVCPFHNNHRDGSQRYIIDKGQVAYHQNYLAG
CCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCEECC
NTPYTVPGSQGGFVTYPSLVEGLKVRKTAPSFLDHFSQARLFWNSMTDVEQSHILQAFSF
CCCEECCCCCCCEEECHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGKVNVPEVRQRVVNLIGHISRPLATAVAEQVGVEPPDKSIKQSDVTKSSPTLSLMNTK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEEEECC
FLPNTLKVAIIVGNGYGGNALESLLESLKEVELKPYIISERLGEITADNGDTLNVDATFL
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCEEEEEEEEE
TTSPVLYDGLLVVGGDHINDQFAYEAGNFITEQFNHYKPIGGMEEGATLIQQLGIANRPG
ECCCHHHCCEEEECCCCCCCHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
VFISQSGSRQFTRQFIDGMAKQRFWDR
EEEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA