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The map label for this gene is trxB [C]

Identifier: 23099806

GI number: 23099806

Start: 2404424

End: 2405410

Strand: Direct

Name: trxB [C]

Synonym: OB2351

Alternate gene names: 23099806

Gene position: 2404424-2405410 (Clockwise)

Preceding gene: 23099802

Following gene: 23099811

Centisome position: 66.23

GC content: 36.88

Gene sequence:

>987_bases
ATGGATAGCAAAGTATTTGATGTAACTATTATCGGAGCAGGGCCAACTGGTTTATTCACTGCTTTCTATGGTGGAATGCG
AGAGGCGAGTGTTAAAATTATTGAAAGCCTTCCTCATATTGGTGGACAGCTAACAGCCCTATATCCAGAAAAATATATAT
ATGACATTGCTGGTTTTCCTAAAGTACATGCTCAAGAATTAATTGACCGCCTTGAAGAACAGGCAAAATTCTTTGATCCG
GAAATTGTTCTTGGACAAGCAATTGATAAAGTAGAACGATTAGAAGATGAGACAATCCGATTAACCTCTAATACTGGAGA
AGTTCATTTAACGAAAACAATAATCATAACAGCAGGAAATGGAGCGTTCCAACCTAGACGCTTAAATATCGGCAACAGTG
AAGCGTTTGAAGGCAAGAACCTTCATTACTACGTAAGAGATATGAATCAATATAAGGGTAAGCGAGTGGTATTATTAGGT
GGAGGCGATTCTGCTGTTGATTGGGCATTGATGTTAGAAAAGATCGCTGCAAAAGTGACACTTGTACATCGACGGGATCA
ATTTCGTGCGCATGAGCACAGCGTCAATCAACTGAAAGAATCCTCCGTAGAAATTCTAACTCCTTATGCACCTATTAATG
TTGAAGCATCCGATAAAATTGAAAAAATTCAACTTCAAGAGGTAAAAGGTGAAAAAATTATTGACGTAGAAGTGGACGAT
ATTATTTGTAATTATGGATTTATATCAAGCCTTGGTCCAATTAAGGATTGGGGATTAGAGATAGAGAAAAATAGTATCGT
TGTAAACTCTAAAATGGAAACTAATATTCCAGGAGTATATGCCGCTGGAGATGTCTGCACATATGATGGGAAAGTAAAAT
TAATAGCAACAGGTTTTGGTGAAGGACCAACAGCTATAAATAATGCGAAAAACTATATTGATCCTAAGGCAAGAATACAA
CCAAAACATTCAACTGCTATGTTTTAA

Upstream 100 bases:

>100_bases
TCTTAACTACTATTCTTCAGTGCGCAAAAATACCAACATAATTCAGTTTATGATACCATTGAAATGGTTATAAATTGTTT
ATATAGAAAAGAGGGGACAT

Downstream 100 bases:

>100_bases
ATTTGAATTAGCTTAGCTAGAAAAATGCATGGAATCCCTATTCCATGCGTTTTTCTATTTAAAGGGATTCTCCTGCACTT
CTAACCATTCACTAATAGTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: FNR 2; Fd-NADP+ reductase 2

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MDSKVFDVTIIGAGPTGLFTAFYGGMREASVKIIESLPHIGGQLTALYPEKYIYDIAGFPKVHAQELIDRLEEQAKFFDP
EIVLGQAIDKVERLEDETIRLTSNTGEVHLTKTIIITAGNGAFQPRRLNIGNSEAFEGKNLHYYVRDMNQYKGKRVVLLG
GGDSAVDWALMLEKIAAKVTLVHRRDQFRAHEHSVNQLKESSVEILTPYAPINVEASDKIEKIQLQEVKGEKIIDVEVDD
IICNYGFISSLGPIKDWGLEIEKNSIVVNSKMETNIPGVYAAGDVCTYDGKVKLIATGFGEGPTAINNAKNYIDPKARIQ
PKHSTAMF

Sequences:

>Translated_328_residues
MDSKVFDVTIIGAGPTGLFTAFYGGMREASVKIIESLPHIGGQLTALYPEKYIYDIAGFPKVHAQELIDRLEEQAKFFDP
EIVLGQAIDKVERLEDETIRLTSNTGEVHLTKTIIITAGNGAFQPRRLNIGNSEAFEGKNLHYYVRDMNQYKGKRVVLLG
GGDSAVDWALMLEKIAAKVTLVHRRDQFRAHEHSVNQLKESSVEILTPYAPINVEASDKIEKIQLQEVKGEKIIDVEVDD
IICNYGFISSLGPIKDWGLEIEKNSIVVNSKMETNIPGVYAAGDVCTYDGKVKLIATGFGEGPTAINNAKNYIDPKARIQ
PKHSTAMF
>Mature_328_residues
MDSKVFDVTIIGAGPTGLFTAFYGGMREASVKIIESLPHIGGQLTALYPEKYIYDIAGFPKVHAQELIDRLEEQAKFFDP
EIVLGQAIDKVERLEDETIRLTSNTGEVHLTKTIIITAGNGAFQPRRLNIGNSEAFEGKNLHYYVRDMNQYKGKRVVLLG
GGDSAVDWALMLEKIAAKVTLVHRRDQFRAHEHSVNQLKESSVEILTPYAPINVEASDKIEKIQLQEVKGEKIIDVEVDD
IICNYGFISSLGPIKDWGLEIEKNSIVVNSKMETNIPGVYAAGDVCTYDGKVKLIATGFGEGPTAINNAKNYIDPKARIQ
PKHSTAMF

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family

Homologues:

Organism=Escherichia coli, GI1787114, Length=325, Percent_Identity=29.8461538461538, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081763, Length=286, Percent_Identity=27.972027972028, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321898, Length=324, Percent_Identity=27.4691358024691, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=27.9503105590062, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FENR2_OCEIH (Q8ENX4)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693272.1
- HSSP:   P0A9P4
- ProteinModelPortal:   Q8ENX4
- SMR:   Q8ENX4
- GeneID:   1015862
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2351
- NMPDR:   fig|221109.1.peg.2348
- HOGENOM:   HBG669726
- OMA:   FQVFELG
- BioCyc:   OIHE221109:OB2351-MONOMER
- HAMAP:   MF_01685
- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103
- PRINTS:   PR00368
- PRINTS:   PR00469

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 36327; Mature: 36327

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: BINDING 16-16 BINDING 35-35 BINDING 43-43 BINDING 48-48 BINDING 88-88 BINDING 123-123 BINDING 284-284 BINDING 325-325

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKVFDVTIIGAGPTGLFTAFYGGMREASVKIIESLPHIGGQLTALYPEKYIYDIAGFP
CCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHEEECCCCC
KVHAQELIDRLEEQAKFFDPEIVLGQAIDKVERLEDETIRLTSNTGEVHLTKTIIITAGN
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEECCC
GAFQPRRLNIGNSEAFEGKNLHYYVRDMNQYKGKRVVLLGGGDSAVDWALMLEKIAAKVT
CCCCCEEECCCCCCCCCCCCEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHEE
LVHRRDQFRAHEHSVNQLKESSVEILTPYAPINVEASDKIEKIQLQEVKGEKIIDVEVDD
EEECHHHHHHHHHHHHHHHHCCCEEECCCCCEECCCCCCHHEEEHEECCCCEEEEEEHHH
IICNYGFISSLGPIKDWGLEIEKNSIVVNSKMETNIPGVYAAGDVCTYDGKVKLIATGFG
EEECCCHHCCCCCCHHCCEEEECCEEEEECCCCCCCCCEEECCCEEEECCEEEEEEECCC
EGPTAINNAKNYIDPKARIQPKHSTAMF
CCCCCCCCCHHHCCCCCEECCCHHCCCC
>Mature Secondary Structure
MDSKVFDVTIIGAGPTGLFTAFYGGMREASVKIIESLPHIGGQLTALYPEKYIYDIAGFP
CCCEEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHEEECCCCC
KVHAQELIDRLEEQAKFFDPEIVLGQAIDKVERLEDETIRLTSNTGEVHLTKTIIITAGN
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEECCC
GAFQPRRLNIGNSEAFEGKNLHYYVRDMNQYKGKRVVLLGGGDSAVDWALMLEKIAAKVT
CCCCCEEECCCCCCCCCCCCEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHEE
LVHRRDQFRAHEHSVNQLKESSVEILTPYAPINVEASDKIEKIQLQEVKGEKIIDVEVDD
EEECHHHHHHHHHHHHHHHHCCCEEECCCCCEECCCCCCHHEEEHEECCCCEEEEEEHHH
IICNYGFISSLGPIKDWGLEIEKNSIVVNSKMETNIPGVYAAGDVCTYDGKVKLIATGFG
EEECCCHHCCCCCCHHCCEEEECCEEEEECCCCCCCCCEEECCCEEEECCEEEEEEECCC
EGPTAINNAKNYIDPKARIQPKHSTAMF
CCCCCCCCCHHHCCCCCEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376