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The map label for this gene is sstT [H]

Identifier: 23099758

GI number: 23099758

Start: 2348248

End: 2349426

Strand: Direct

Name: sstT [H]

Synonym: OB2303

Alternate gene names: 23099758

Gene position: 2348248-2349426 (Clockwise)

Preceding gene: 23099757

Following gene: 23099761

Centisome position: 64.68

GC content: 35.37

Gene sequence:

>1179_bases
ATGAAACAATTTGGACTACTTATCCGAATCATCCTAGCTATAGTTCTTGGTATAGCTTTCGGAACATTTGCCAATGAATG
GCTTGTACGATTATTTGCTACTTTTAATGACATTTTTGGTGGCTTTTTAACTTTCATTATTCCCCTTATTATCATTGGGT
TTATTGCACCAGGTATAGGTTATATGGGGAAAGGGGCAGGAAAACTTCTCAGCATAACAGCACTTATGGCTTACATTTCT
ACAATAATTGCAGGAATTGTAGCGTTTCTATCTGCTAAGGCACTATATCCTAGTATTTTAAGTGGACACAGTTTAAAAAT
GTTTGACGATCCAAGCAGTGCTTTAGAAACTGGCTTCTTATCCTTTGAACTTACTCCACCTTTAGAAGTCGTGACTGCAC
TTATATTAGCCTTCGTACTAGGTATTGGAGCTGCAGCAATTAAAAGTGACTCGTTGCTAAACGTAATGACTGATTTTAGG
TCTATCATTGAATTAGTTATACAAAAAGTTATTATTCCATTACTCCCAATTCATATTTTTGGAATCTTTACAAATATGAC
TTATGCAGGTCAAGTAGCTTCCATATTAAGTGTATTTGCAGTTGTTTTTGCGATGATTATTGTATTACATATCATATACT
TGATAATTCAATATACGATTGCTGGAACATTAAGTCGACAAAATCCATTTAGTATGCTCAAAAAAATGATACCGGCATAT
TTTACAGCTTTAGGTACCCAATCTTCTGCTGCCACCATTCCGGTAACATTACAGCATACGAAAAAATTACATGTAAAAGG
AAATGTTGCTGATTTTACTGTACCCCTATTAGCAAACATACATTTATCAGGGAGTACCATTACGATAACTAGCTGTGCAT
TAGCTGTAATGTTTTTACAAGGATCTGTTGCTACAATTGGTTCGGTATTGCCATTTTTACTTGTATTAGGAGTAACAATG
ATTGCTGCACCTGGCGTTCCTGGCGGCGCTGTAATGGCTGCTATAGGATTATTAGATACTATGTTAGGTTTCGGACCTAC
AATGGTTTCATTAATGATCGCTTTATATCTTGCACAAGATAGTTTAGGAACAGCTTGTAATGTAACAGGCGACGGAGCAA
TTACAAGTATCGCAGATTCAATAAATAATAAGTGGAAAATAACAAATGATGATGCTTAA

Upstream 100 bases:

>100_bases
CTCCTCTTTTTCCTTTTTTATACACTAGCATATAGAAATAATTATGTGTATAATTGTTAGAATAATTACATCATCATTGA
ATTAAGGAGAGAGAACTATC

Downstream 100 bases:

>100_bases
TTTTCACTAAAATATTTTACTAAAAACAGCCTTTTCCGACTTGGAAAAGGCTGTTTTTATATGGTCTAAGATAATGATTA
AGTTAAAAAGTCTCTAGAGT

Product: sodium:dicarboxylate symporter

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKQFGLLIRIILAIVLGIAFGTFANEWLVRLFATFNDIFGGFLTFIIPLIIIGFIAPGIGYMGKGAGKLLSITALMAYIS
TIIAGIVAFLSAKALYPSILSGHSLKMFDDPSSALETGFLSFELTPPLEVVTALILAFVLGIGAAAIKSDSLLNVMTDFR
SIIELVIQKVIIPLLPIHIFGIFTNMTYAGQVASILSVFAVVFAMIIVLHIIYLIIQYTIAGTLSRQNPFSMLKKMIPAY
FTALGTQSSAATIPVTLQHTKKLHVKGNVADFTVPLLANIHLSGSTITITSCALAVMFLQGSVATIGSVLPFLLVLGVTM
IAAPGVPGGAVMAAIGLLDTMLGFGPTMVSLMIALYLAQDSLGTACNVTGDGAITSIADSINNKWKITNDDA

Sequences:

>Translated_392_residues
MKQFGLLIRIILAIVLGIAFGTFANEWLVRLFATFNDIFGGFLTFIIPLIIIGFIAPGIGYMGKGAGKLLSITALMAYIS
TIIAGIVAFLSAKALYPSILSGHSLKMFDDPSSALETGFLSFELTPPLEVVTALILAFVLGIGAAAIKSDSLLNVMTDFR
SIIELVIQKVIIPLLPIHIFGIFTNMTYAGQVASILSVFAVVFAMIIVLHIIYLIIQYTIAGTLSRQNPFSMLKKMIPAY
FTALGTQSSAATIPVTLQHTKKLHVKGNVADFTVPLLANIHLSGSTITITSCALAVMFLQGSVATIGSVLPFLLVLGVTM
IAAPGVPGGAVMAAIGLLDTMLGFGPTMVSLMIALYLAQDSLGTACNVTGDGAITSIADSINNKWKITNDDA
>Mature_392_residues
MKQFGLLIRIILAIVLGIAFGTFANEWLVRLFATFNDIFGGFLTFIIPLIIIGFIAPGIGYMGKGAGKLLSITALMAYIS
TIIAGIVAFLSAKALYPSILSGHSLKMFDDPSSALETGFLSFELTPPLEVVTALILAFVLGIGAAAIKSDSLLNVMTDFR
SIIELVIQKVIIPLLPIHIFGIFTNMTYAGQVASILSVFAVVFAMIIVLHIIYLIIQYTIAGTLSRQNPFSMLKKMIPAY
FTALGTQSSAATIPVTLQHTKKLHVKGNVADFTVPLLANIHLSGSTITITSCALAVMFLQGSVATIGSVLPFLLVLGVTM
IAAPGVPGGAVMAAIGLLDTMLGFGPTMVSLMIALYLAQDSLGTACNVTGDGAITSIADSINNKWKITNDDA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI40254478, Length=280, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789473, Length=247, Percent_Identity=25.1012145748988, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983106, Length=273, Percent_Identity=27.4725274725275, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=273, Percent_Identity=27.4725274725275, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537407, Length=180, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 41380; Mature: 41380

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEECCCCCCHHHHHHHHCCCCEEECCCCC
>Mature Secondary Structure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CCCCEECCCCCCHHHHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]